Hologic ThinPrep 5000 Instruction Manual page 10

Table 8: Independent Pathologist Results by Site, LSIL and More Severe Lesions
Cases
Site
Positive by
Independent
Pathologist
S1
S2
S3
H1 116
H2 115
H3 126
For LSIL and more severe lesions, the diagnostic comparison statistically favored the
ThinPrep method at three sites and was statistically equivalent at three sites.
Table 9: Independent Pathologist Results by Site,
Cases
Site
Positive by
Independent
Pathologist
S1
101
S2
109
S3
170
H1
H2 171
204
H3
For ASCUS/AGUS and more severe lesions, the diagnostic comparison statistically favored
the ThinPrep method at two sites and was statistically equivalent at four sites.
ThinPrep
Positive
50 33
65 48
77 54
102
86
120
ASCUS/AGUS and More Severe Lesions
®
ThinPrep
Positive
92 72
85
95
155
143
190
Conventional
p-Value
Positive
25 0.170
33 0.042
33 <0.001
81 <0.001
90 0.876
112 0.170
Conventional
p-Value
Positive
68 0.900
59 0.005
65 <0.001
143 0.237
154 0.330
191 1.000
MAN-04008-001 Rev. 001
Method
Favored
Neither
ThinPrep
ThinPrep
ThinPrep
Neither
Neither
Method
Favored
Neither
ThinPrep
ThinPrep
Neither
Neither
Neither
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