Agilent Technologies 1200 Infinity Series User Manual page 7

1
What is the HDR-DAD Solution?
30x wider linear UV-range – Quantification of widely different concentrations in a single run
This is achieved by Agilent's Max-Light flow cells. Optofluidic waveguides in
these flow cells facilitate total internal reflection for superior light
transmission. This significantly reduces the detector noise regardless of the
length of the flow path.
The HDR-DAD solution combines two Agilent Diode Array Detectors
(possible combinations: G4212A/B x G4212A/B or G7117A/B x G7117A/B);
one is fitted with a 3.7 mm path length flow cell, while the other has a longer
60 mm path length flow cell. The signal from the longer path length cell
quantifies the low concentrations and the signal from the shorter path length
cell is used for the high concentrations. Special algorithms correct the
different retention times and compute these signals to one HDR signal.
Compared with an earlier generation Agilent diode array detector, the HDR
signal covers a 30 times higher linear dynamic range.
Achieve up to 30-fold greater UV-sensitivity
The Agilent HDR-DAD solution extends the upper linearity level nearly
three-fold – from 2 to typically 6 absorbance units – which allows you to inject
three-fold more sample and simultaneously benefit from 10-fold lower
detector noise. This solution gives you up to 30-fold greater sensitivity for
simultaneous analysis and quantification of main compounds and impurities.
You gain more confidence in automated peak integration and achieve greater
area precision for trace-level components.
HDR-DAD Solution 7