Related Manuals for BioCare Medical ARC
Summary of Contents for BioCare Medical ARC
- Page 1 Antigen Retrieval Chamber (ARC) Manual - Research Use Only (RUO) Digital programmable pressure system for heat-induced epitope retrieval...
- Page 2 Biocare Medical Technical Support: 800-799-9499 Option 3 Customer Service: 800-799-9499 Fax: 925-603-8080 Corporate Office: 60 Berry Drive Pacheco CA 94553 www.biocare.net...
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Page 3: Table Of Contents
Quick Instruction Guides ......................................... 19 Instrument Operation ........................................ 19 Software Reports ........................................19 Additional Consumables ........................................20 ARC Flash Drive with Reporting Software ................................. 21 Summary of Consumables ....................................... 21 Symbol Glossary ..........................................22 Warning Symbol Glossary ........................................ 22 Software Errors ..........................................23... -
Page 4: Overview
121°C. The ARC is suitable for deparaffinization with the appropriate reagents. WARNING: Do not use the ARC for any other purpose than stated in this manual. Failure to adhere to these guidelines may result in damage to the instrument or personal injury. -
Page 5: Transportation
Storage environment is 10-50°C (50-122°F), 10-80% non-condensing relative humidity. Do not stack. Protect from moisture. Not to exceed one year (12 months) in storage. Handling The ARC may be safely handled, installed, and operated by one person capable of lifting 25 pounds (11.3 kg). Lift by the handles only. Do not move until unit is completely cooled. Environmental Conditions... -
Page 6: Service
Reagents must always be used according to the manufacturer’s instructions and good laboratory practices. Always wear gloves, eye protection and a protective lab coat when handling any chemical solution used on the ARC. Obtain the SDS from the manufacturer for each chemical constituent. Do not use any flammable chemicals on or in the ARC. -
Page 7: Parts & Features
Parts & Features 1. System Lid 9. USB Port 2. Sealing Gasket 10. Base 3. Rubber Grommet 11. ON/OFF Power Switch 4. Water Chamber 12. Power Cord Socket 5. Upper Ring 13. Pressure Limit Valve 6. Handle 14. Canister Basket 7. -
Page 8: Important Safeguards
3. Never attempt to open lid while the unit is greater than or equal to 95C. Do not open the ARC until the unit has cooled to below 95C and all internal pressure has been released. If lid is difficult to rotate, this indicates that the chamber is still pressurized. -
Page 9: Before First Use
Thoroughly clean the lid and the metal water chamber. 1. Place the ARC on a clean, flat surface where you intend to use it. Position the unit with easy access to the plug for emergency disconnect action in case of malfunction. - Page 10 Warning do not plug the unit into the Japanese style outlets , or any outlet that’s not labeled with a 115V ± 10% rating. 5. Ensure the ARC is on the Home Screen, which will display: Current temperature of the unit...
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Page 11: Instructions For Use
Once the ARC is appropriately set up, antigen retrieval can begin. 1. If not already plugged in, plug the power cord first into the ARC and then into the appropriate wall outlet or transformer (refer to Initial Set-Up 4b) Turn ON / OFF switch to the ON position (|). -
Page 12: Control Panel Programming
Wait for the Home Screen to be displayed iii. Select the Start a Custom Protocol button Note: Altitude affects the maximum allowed protocol temperature. The ARC calculates the highest temperature allowed to accurately controlled operation at any operating altitude. - Page 13 b. After a Run i. Wait for the ongoing run to complete and for the Run Complete screen to be displayed ii. Select the Save Protocol button iii. Observe that the Overwrite Saved Protocol screen is displayed iv. Select the desired Page with the Up/Down arrow buttons v.
- Page 14 Once everything has been checked, select the Start Run button to begin the protocol. Note: Before starting a run, the temperature of the ARC should be at least 3°C lower than the desired set point. 4. The unit will now show the run screen during the protocol progress. During a run, the screen conveys several pieces of information: a.
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Page 15: Program Completion
3. Press the Home button to continue. 4. The ARC will then show a Liquid Too Warm screen. This screen shows the current temperature of the water chamber. a. This screen will remain until the water chamber temperature reaches 80°C. A new run cannot be started while this screen is displayed. -
Page 16: Preheating Function
Preheating Function The ARC can preheat retrieval solutions when a Custom Protocol with a hold temperature min. 5°C below the boiling point is selected. The preheat functionality temporarily pauses the unit when the target (hold) temperature is reached, allowing the user to add deparaffinized slides to retrieval buffers that have already been warmed to the target temperature. -
Page 17: Reporting Software
USB Flash Drive The ARC has the ability to record and export run data to a USB drive. The data includes run ID, run date, start time, protocol temperature, protocol hold duration, and pressure. The run ID is an automatically assigned sequential number for each run performed on an ARC unit. - Page 18 1. Click on the Summary Report by Instrument button. 2. In the “Serial” option window, select the serial number of the desired ARC from the drop-down list. Alternatively, leave the Serial option set to “All” to generate a Summary List of all uploaded ARC run files.
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Page 19: Maintenance
3. Remove the condensation collector and empty of any accumulated water. 4. Leave lid unlocked. 5. Do not leave liquids in the ARC when not in use. 6. Wash the metal slide canisters in soap and water. Thoroughly rinse the metal slide canisters with DI water. Do not use bleach. -
Page 20: Troubleshooting Guide
Troubleshooting Guide Symptom Possible Reasons Solutions Lid does not lock The sealing ring is not properly installed Reinstall the ring The pressure is too high Wait until the pressure drops Cannot open the lid after a run Residue on the sealing ring Clean the sealing ring The sealing ring is worn out Replace using the sealing gasket kit... -
Page 21: Quick Instruction Guides
11. Once the unit is cool, remove metal water chamber and properly dispose of water. Dry outside completely before placing in unit and close the lid. Please Note: Before starting a run, the temperature of the ARC should be at least 3°C lower than the desired set point. Software Reports Transfer USB flash drive from ARC to PC. -
Page 22: Additional Consumables
ARC Standard Canister The ARC is supplied with 3 s tanda rd s lid e metal slide canisters. Metal canisters allow for ideal heat transfer and are the recommended container for holding slides in the ARC when processing standard width slides. Do not use plastic or glass slide holders. -
Page 23: Arc Flash Drive With Reporting Software
Steam Monitor Strips The heat and pressure sensitive steam strip allows the end-user to monitor both pressure and heat inside the ARC. The best temperature for a Steam Monitor strip to show quality control is above the boiling point of water. It is at this temperature and relative pressure that a dark brown to black color is achieved. -
Page 24: Symbol Glossary
Consult instructions for use Requires recycling as electrical waste Power USB connector Power socket Warning Symbol Glossary Hot Surface Biohazard Caution, consult accompanying documents Electrical Shock Hazard Pinch/Crush Hazard Please contact Biocare Medical Technical Support if any problems arise: 800-799-9499 Option 3. -
Page 25: Software Errors
Software Errors Error Description Incorrect checksum Pressure valve error Ambient pressure error Temperature is above the safety limit Temperature is out of range Temperature is out of range during the hold phase Heater temperature exceeds limit during ramp Heating too quickly (thermal mass too low) 300 to 302 Error writing to USB Serial number error (unassigned) - Page 26 800.799.9499 60 Berry Drive Pacheco CA 94553 904-012RUO-112823...
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