3DHISTECH TMA Grand Master 2.6 User Manual
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3DHISTECH TMA Grand Master 2.6 User Manual

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TMA Grand Master
2.6
User's Guide
December 9, 2016
GM26-UG-EN Rev1
Rev. 1

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Summary of Contents for 3DHISTECH TMA Grand Master 2.6

  • Page 1 TMA Grand Master User’s Guide December 9, 2016 GM26-UG-EN Rev1 Rev. 1...

  • Page 2: Table Of Contents

    TMA Grand Master 2.6 – User’s Guide Contents Disclaimer............................4 Declaration Of Conformity......................6 Character Formats and Symbols....................7 Terms and abbreviations......................8 1 Intended Use..........................9 1.1 Main Features of TMA Grand Master....................9 1.2 New Features............................10 2 TMA Grand Master Hardware....................11 2.1 TMA Grand Master Main Unit......................11 2.2 Cabling..............................12...
  • Page 3 TMA Grand Master 2.6 – User’s Guide 5.3 Inserting Recipient Blocks........................43 5.4 Inserting Donor Blocks.........................46 5.5 Launching the transfer process......................48 5.6 Slide overlay............................55 5.7 Import data............................62 5.8 Restore medical information database....................64 5.9 Exporting donor block data........................65 5.9.1 Export................................65 5.9.2 Search................................70 5.10 Batch removal of blocks........................72...

  • Page 4: Disclaimer

    IP are the sole properties of the 3DHISTECH Ltd. 3DHISTECH Ltd. is not liable for damage of whatever nature (including, but not limited to, general or specific damage, indirect damage, consequential damage or incidental damage, including the...
  • Page 5 Third-Party Disclaimer (LibTIFF – TIFF Library and Utilities) 3DHISTECH Ltd. is not liable for damage of whatever nature (including, but not limited to, general or specific damage, indirect damage, consequential damage or incidental damage, including damage resulting from lost profits, interruption of business, loss of business information, pecuniary loss or similar damage) that stems from or is associated with the incorporated part of this Product that is made by Silicon Graphics Inc.

  • Page 6: Declaration Of Conformity

    Declaration Of Conformity Declaration Of Conformity 3DHISTECH Ltd. declares that the product TMA Grand Master is designed and produced with consideration of specified requirements according to the IEC 61326-2-6:2005 standard, and conforms to the directives and other standards listed below: IEC 61010-1:2001 (ed.

  • Page 7: Character Formats And Symbols

    TMA Grand Master 2.6 – User’s Guide Character Formats and Symbols Character Formats and Symbols Example Abbreviation or term that is explained in the section Terms and Abbreviations. Example Words or characters that appear on the screen. These include field names, screen titles, pushbuttons and menu names, paths or options.

  • Page 8: Terms And Abbreviations

    TMA Grand Master 2.6 – User’s Guide Terms and abbreviations Terms and abbreviations Digital slide / Slide Slide digitized with a scanner microscope, for example Pannoramic SCAN. Consists of an MRXS file and a folder with the same name as the MRXS file.

  • Page 9: Intended Use

    TMA Grand Master 2.6 – User’s Guide 1 Intended Use 1 Intended Use TMA Grand Master is a software-controlled electronic laboratory device that automates the creation of tissue microarrays (TMAs) and also the process of PCR sampling. The creation of TMA blocks (by taking tissue core samples from donor blocks and inserting them into recipient blocks) and the insertion of extracted tissue cores into PCR tubes is controlled by using a graphical user interface.

  • Page 10: New Features

    TMA Grand Master 2.6 – User’s Guide 1 Intended Use 1.2 New Features Windows 10 compatibility • New GUI and themes • Redesigned settings menu • Redesigned about window • Faster and more effective barcode reading • Advanced search option for CaseCenter users •...

  • Page 11: Tma Grand Master Hardware

    TMA Grand Master 2.6 – User’s Guide 2 TMA Grand Master Hardware 2 TMA Grand Master Hardware Hardware: TMA Grand Master main unit • Control computer with a monitor, a mouse and a keyboard • USB cables between the main unit and the control computer •...

  • Page 12: Cabling

    TMA Grand Master 2.6 – User’s Guide 2 TMA Grand Master Hardware Back View Figure 2 – TMA Grand Master back view 1. Terminal point for the power supply cord 2. Main power supply switch 3. Fuse compartment 4. USB ports to connect with the computer.

  • Page 13: Delivery

    TMA Grand Master 2.6 – User’s Guide 2 TMA Grand Master Hardware Warning! Only connect external devices that are safety extra low voltage rated to the TMA Grand Master instrument to avoid the risk of electrical shock. 2.3 Delivery Package 1 TMA Grand Master main unit (packed in a mandatory polyethylene container in a •...

  • Page 14: Installing And Configuring Tma Grand Master Hardware

    Warning! Only qualified personnel may install TMA Grand Master and perform the initial start-up procedure. 3DHISTECH Service technicians install and configure TMA Grand Master and hand it over to you in operating condition. 2.5 Transporting the TMA Grand Master Main Unit...
  • Page 15 TMA Grand Master 2.6 – User’s Guide 2 TMA Grand Master Hardware 3. Lift the main unit by its recessed transporting handles that can be found both sides of the bottom plate, underneath the side-plates of the main unit. Figure 4 – Transporting handle 4.

  • Page 16: Installation Of Tma Control Software

    500 GB – for saving the TMA database, and for storing digital slides 3.2 TMA Control Software Installation Important! 3DHISTECH service technicians perform the installation and configuration of the TMA Control software. The following installation procedure is for information purposes only – follow the below steps only if you need to re-install the software, or upgrade to a newer software version.
  • Page 17 TMA Grand Master 2.6 – User’s Guide 3 Installation of TMA Control Software 1. Launch the TMAControl_2.6_RTM_x64.exe file that you received on a 3DHISTECH Installation Disc or downloaded in a compressed file. 2. Follow the instructions in the installation wizard.
  • Page 18 TMA Grand Master 2.6 – User’s Guide 3 Installation of TMA Control Software 4. The installer notifies you if it cannot find the prerequisites. Click Install to start the installation of missing prerequisites. 5. Click Next to continue with the installation of the TMA Control software application.
  • Page 19 TMA Grand Master 2.6 – User’s Guide 3 Installation of TMA Control Software 6. Select the type of license – browse for the license file or select HASP dongle. 7. Choose the installation folder for the TMA Control software application. Click Browse for locating a different folder than the default one, then click Next to continue.
  • Page 20 TMA Grand Master 2.6 – User’s Guide 3 Installation of TMA Control Software 8. Choose the Start menu folder. 9. After completing the installation of TMA Control, click Finish to close the wizard. Important! After the installation, RW access right to database and configuration file must be granted for Admin and Standard users.

  • Page 21: Operating The Main Unit

    TMA Grand Master 2.6 – User’s Guide 4 Operating the Main Unit 4 Operating the Main Unit 4.1 Switching the Main Unit On or Off Turning the Power On 1. Switch on the TMA Grand Master (first, the main switch on the back panel – see Figure 2 (2), then the one in the front –...
  • Page 22 TMA Grand Master 2.6 – User’s Guide 4 Operating the Main Unit Warning! You receive a warning message after starting the software, if not having a valid license for running the application. A separate license is necessary to activate the PCR function of the TMA Control software.
  • Page 23 TMA Grand Master 2.6 – User’s Guide 4 Operating the Main Unit To load an existing project, the following window is displayed after clicking Load, in which you can select the desired project to be loaded, and narrow project list by activating Date Range and/or Diameter filters.

  • Page 24: Main User Interface

    TMA Grand Master 2.6 – User’s Guide 4 Operating the Main Unit 4.3 Main User Interface This version of TMA Control offers two different views of recipient and donor block panels. Based on the loading and processing method of blocks the normal view includes thumbnails of all recipient tray positions, and as for donor blocks the selected tray is displayed in its full capacity.

  • Page 25: Main Toolbar

    TMA Grand Master 2.6 – User’s Guide 4 Operating the Main Unit If you want to load a recipient block into the unit, click at the Unused Block(s) panel header. As for donor blocks, first click the button, then if there is a free slot on the actual tray, the door can be opened (otherwise wait until the closest tray with a free slot on it is rotated to loading position) and the block can be inserted.
  • Page 26 TMA Grand Master 2.6 – User’s Guide 4 Operating the Main Unit - Settings window contains the settings for some important features in TMA Control, including Overlay, Restore Medical Information Database, Depths, Images, Layout, Barcode, and Theme. See section 5.11 Settings for more information.
  • Page 27 NOTE: Before opening the videos, make sure to copy video files to <C:\Program Files\3DHISTECH\TMA Control\Videos> folder from the installation disk. This folder may be hidden, and thus requires authentication. Links – Company and product web page links are displayed here.

  • Page 28: Inserting And Removing Blocks

    TMA Grand Master 2.6 – User’s Guide 4 Operating the Main Unit 4.4 Inserting and Removing Blocks 4.4.1 Block preparation Warning! If the paraffin swells through the bottom or the sides of the plastic cassette, cut off the excess paraffin before inserting the block into the main unit.

  • Page 29: Cleaning Block And Pcr Cassette Preparation

    TMA Grand Master 2.6 – User’s Guide 4 Operating the Main Unit 4.4.2 Cleaning block and PCR cassette preparation Important! Before inserting a PCR cassette into its slot, ensure that the cover plate and tubes are uncontaminated. One PCR cassette can be inserted into its slot before the first position on each donor tray.

  • Page 30: Inserting A Block Into The Main Unit

    TMA Grand Master 2.6 – User’s Guide 4 Operating the Main Unit Important! Before starting a larger project it is advised to calculate the number of cores that will be inserted to PCR tubes, so placing a sufficient number of cleaning blocks accordingly.
  • Page 31 TMA Grand Master 2.6 – User’s Guide 4 Operating the Main Unit 2. For the recipient blocks (1) click the button next to the image of the specific block pairs. Depending on the donor block tray that you want to rotate to inserting position, click the tray ID: A –...

  • Page 32: Removing A Block From The Main Unit

    TMA Grand Master 2.6 – User’s Guide 4 Operating the Main Unit 4.4.4 Removing a block from the main unit 1. Recipient block positions are displayed in a double-column on the left side of the screen. Donor block tray positions are identified by six buttons (A-F). The Change Blocks buttons are responsible for rotation of the donor block holder cylinder.
  • Page 33 TMA Grand Master 2.6 – User’s Guide 4 Operating the Main Unit 3. Open the tool exchanger compartment door. Figure 7 – Tool compartment 4. Loosen the drill chuck locking lever (marked with red) that fixes the drill chuck in position and remove the drill chuck by lifting it upwards.
  • Page 34 TMA Grand Master 2.6 – User’s Guide 4 Operating the Main Unit 5. Hold the front cog wheel firmly and loosen the rear cog wheel (marked with red) and turn it anticlockwise about two turns (360-720 degrees), then remove the drill bit from the drill chuck.
  • Page 35 TMA Grand Master 2.6 – User’s Guide 4 Operating the Main Unit 10. Pull out the piston, then hold the front cog wheel firmly and unscrew the rear cog wheel (marked with red) by turning it anticlockwise about two turns (360-720 degrees), and now you are able to remove the puncher.

  • Page 36: Using Tma Grand Master

    TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master 5 Using TMA Grand Master This TMA Grand Master device is designed to create TMA blocks and make it available for you to place extracted cores into PCR tubes at the same time, within the same process. With the operating software you may set processes for creating TMA blocks or PCR sampling exclusively or both.

  • Page 37: Before You Start

    TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master 5.1.1 Before You Start Warning! Do not use paraffin blocks which dimension values are higher than specified (24mm (W) x 37mm (H) x 10mm (D)), otherwise the drilling and punching heads may be damaged.
  • Page 38 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master New layout (TMA block array) can be created or edited in the Layout Editor window. Already existing layout can be selected from the Select Layout drop-down list. When you create a new pattern, you define the block layout. Type the name of your new layout into the Name textbox (maximum length is 20 characters).
  • Page 39 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master Figure 12 – Layout pattern If you activate the Use Sectors function, the layout can be divided into several sectors. Mark • an area within the array with the mouse by drawing a border around the group of insertion positions.
  • Page 40 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master The filling of sectors will be processed uniquely during TMA block creation, one sector is • completed at a time, then the device processes the upcoming sector you have created.
  • Page 41 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master It is also available to use dividing rows and columns in the block by leaving active spots • between the sectors that can be filled up with Agarose or other tissue (for example, liver) that differs in color from the core tissue.

  • Page 42: Modifying A Recipient Block Layout

    TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master Important! The table below shows the maximum number of holes can be drilled into a paraffin block depending on hole sizes: Paraffin Block Size (mm) Hole Sizes (mm) Max.

  • Page 43: Deleting A Recipient Block Layout

    TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master 5.2.3 Deleting a recipient block layout If you wish to delete the layout for the selected block, click next to the block image Open either the Layout Editor window.
  • Page 44 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master 4. Select a layout for the recipient block: a) Click the image of the recipient block for which you want to add a layout: b) Select a pre-defined layout from the Select Layout drop-down list in the Layout Editor window, then click Use this layout.
  • Page 45 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master Important! If loading a PCR cassette in the tray, make sure to insert the necessary amount of cleaning blocks into recipient block positions. 5. The recipient block barcode is automatically identified, but if not recognized properly, the following message appears: Click Yes, and the Barcode window is opened in which you can modify settings.

  • Page 46: Inserting Donor Blocks

    TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master 5.4 Inserting Donor Blocks 1. Insert donor blocks into the first tray, positions A1-10. For more information see section 4.4.3 Inserting a block into the main unit. Warning!
  • Page 47 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master If you have already logged in to CaseCenter, after accepting the donor ID, click the software automatically searches for the corresponding slide stored on the server. Furthermore, if other locations have been defined in the Settings window for overlay images, more images can be found with an identical ID.

  • Page 48: Launching The Transfer Process

    TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master 5. After the barcodes of donor or recipient blocks are identified, they are automatically displayed both in the Recipient Block ID and Donor Block ID fields. If barcode reading had not been previously set, the Barcode panel of Settings window appears in which you can specify the barcode type and set it as default for the entire project.
  • Page 49 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master NOTE: The first tube position must always be on the left bottom of the cassette, and the cover plate tab faces to the left side of the device. After you have activated the PCR function by clicking the PCR button, make sure to insert cleaning blocks (or mark a sufficient amount of recipient block as cleaning blocks).
  • Page 50 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master NOTE: Image Editor function is inactive if a block is marked as cleaning block. If there is no such button visible on the block image, go to Settings/Images panel, then activate Image Editor function.
  • Page 51 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master Important! Each donor position has its adherent PCR position (for example, A6–PCR6) and because of the maximum number of PCR markers allowed to place on a donor block is four, each PCR tube can contain up to four cores of the corresponding donor block.
  • Page 52 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master NOTE: You can interrupt the punching process anytime by clicking the Stop button. The stop function (represented by the Stop button in the application window) can be called by pressing a relevant hotkey that is the Pause key by default.
  • Page 53 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master When you place the cursor over the location of an extracted core, the spot on the recipient block is marked by the center point of the blue crosshair.
  • Page 54 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master If you remove a donor block to which cores are selected to be transferred, the software displays a message to warn you to place the block back to its position.

  • Page 55: Slide Overlay

    TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master 7. If TMA Grand Master has finished the creation of TMA blocks and samples have been transferred into PCR tubes, do the following: Exit the TMA Control application by clicking Exit.
  • Page 56 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master If a note has been added to a marker in CaseViewer, the note and the color of the marker will be displayed in the Excel sheet in a separate column when exporting block data.
  • Page 57 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master If the software cannot find a slide or image at the defined locations, the Browse Overlay Slide window is opened in which paths of slide and/or jpg images can be set in the text boxes for automatic overlay.
  • Page 58 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master 5. In CaseCenter, browse for the slide in the folder tree, then left click on the slide to import it. NOTE: Make sure that Open slides in Application option is selected in CaseCenter.
  • Page 59 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master 9. In the appearing Manual Overlay window, imported slide image is displayed at the left and as overlaid on the donor image at the right, accordingly, additional functions such as Opacity, Zoom, Rotate, and Flip are available for you in the extended panel to set the proper orientation.
  • Page 60 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master You can also modify the transparency level of the JPG image layer by moving the • Opacity slider, allowing you to set how much the slide image should obscure the donor block image.
  • Page 61 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master NOTE: As marker colors and their names will be displayed in the relating cells of the Annotation color column on the export sheet, to omit the usage of those colors that can...

  • Page 62: Import Data

    TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master 5.7 Import data To import donor block-related data, do the following: 1. Click Import at the main menu bar of the application window. 2. Click Browse in the Import window to search for the data file to be imported. If the ID of the donor block loaded into the device exists in the imported database, the data set of the specific donor block can be appended to the database.
  • Page 63 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master 3. The content of the MedicalInfos data sheet can be modified with the Merge or the Replace function. The imported data are stored in the MedicalInfos data sheet that can be selected as a record when exporting.

  • Page 64: Restore Medical Information Database

    TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master In this case, the already existing data is archived and can be accessed after clicking Settings. Click Restore in the Settings window to restore the original data set (see 5.11 Settings for more information).

  • Page 65: Exporting Donor Block Data

    TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master 5.9 Exporting donor block data 5.9.1 Export If you have finished the transfer process from donor to recipient block(s), you can export block-data to a spreadsheet file (separate worksheets will be created within the file for each block).
  • Page 66 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master Schemes can be defined based on database-driven project handling by creating a scheme or selecting one from the Scheme drop-down list. If you want to create a new scheme, first click then you can custom-define a record set from the SQL database of the related project.
  • Page 67 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master 3. Set database name, path, and type. To export data to a new file (will be generated by the application), browse for the folder by clicking Browse at the Database Name, Path, and Type section, type in a file name, and finally, select the desired file format (ODS/XLS/XLSX/CSV).
  • Page 68 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master The second sheet contains recipient block-related data table where the core IDs are shown according to their positions in the layout. The third sheet contains recipient block-related data table where the Donor Block IDs are shown according to their positions in the layout.
  • Page 69 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master In mixed mode, the application creates a separate file for PCR-related data. The file name is extended with the PCR suffix. The worksheet includes Donor ID and image with the relevant number of PCR sample.

  • Page 70: Search

    TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master 5.9.2 Search The Custom Export window includes a Search panel through which TMA data stored in the database can be filtered, and you can search for Date, Project name, Recipient Block Name, Donor Block Name, Diameter and Medical Information data.
  • Page 71 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master NOTE: When selecting the Donor name, PCR donor heights are not listed if the data are created with a previous software version (older than v2.6) If Block info button is active, and Diameter filter option is added, results are listed according to Recipient name in the first column.

  • Page 72: Batch Removal Of Blocks

    TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master NOTE: If an additional filter is added, the previously set filter setting will be inactive and cannot be modified. 5.10 Batch removal of blocks When you close a project, the software offers you the option “Batch out” through which it is available for you to remove all the blocks (donor and recipient) from the device in one session.

  • Page 73: Settings

    TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master 5.11 Settings The Settings window contains four panels on which function-related options can be activated and further settings can be modified. Overlay Slide image locations can be set for the Overlay function, both in local and CaseCenter folders.
  • Page 74 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master Restore Medical Info Database On the Restore Medical Info Database panel select the database that you want to restore, then click Restore. The database then will be used as the basis for your project data.
  • Page 75 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master Warning! If the tissue specimen sticks to the base plate of the cassette so that the puncher cannot take out the core entirely or properly, you may specify a negative value at the Punching depth (μm) field.
  • Page 76 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master Layout Layout numbering direction and row/column labeling settings are presented in this panel. Labeling display • Activate the Show row and column labeling on layout option to display labels in layout editor and on the recipient block image.
  • Page 77 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master Labeling direction (increasing/decreasing)can be set for rows and columns separately by clicking Labeling position • Select one of the positioning modes Align to block edges or Align to core position.
  • Page 78 TMA Grand Master 2.6 – User’s Guide 5 Using TMA Grand Master NOTE: VintaSoft occasionally cannot read Data Matrix barcodes. Once the Matrox option is selected, set the type (2D, 1D, 1D CDV) and the subtype of the specific group from the drop-down list.

  • Page 79: Maintenance Of Tma Grand Master

    TMA Grand Master 2.6 – User’s Guide 6 Maintenance of TMA Grand Master 6 Maintenance of TMA Grand Master Follow the maintenance and cleaning tasks discussed in this section to ensure the fail-safe operation of the TMA Grand Master device.

  • Page 80: Opening The Service Compartment Door

    TMA Grand Master 2.6 – User’s Guide 6 Maintenance of TMA Grand Master 6.2.1 Opening the Service Compartment Door Service compartment might be cleaned in order to remove dust or objects dropped in. To remove the door of the service compartment do the following: 1.

  • Page 81: Replacing Fuses Of The Main Power Switch

    TMA Grand Master 2.6 – User’s Guide 6 Maintenance of TMA Grand Master 6.3 Replacing fuses of the main power switch 1. Switch off the main power supply and disconnect the power cable. 2. The fuse compartment is located next to the main power supply switch at the back side of the TMA Grand Master.

  • Page 82: Contaminated Tray Or Touch Sensor Surface

    TMA Grand Master 2.6 – User’s Guide 6 Maintenance of TMA Grand Master 5. Replace fuses, put the insert back into its mounting, and push it inwards until you hear a snap, so the lever locks. Figure 17 – Replacing the fuses Important! Use T3.15A/250V fuses only.
  • Page 83 TMA Grand Master 2.6 – User’s Guide 6 Maintenance of TMA Grand Master After performing the above actions, and you have closed the door, the touch sensor must be • cleansed as well. According to the instructions in the following message, by using a dry and clean cloth, gently rub the bottom surface of the touch sensor (sensor is marked with red in Figure 18).

  • Page 84: Troubleshooting Tma Grand Master

    TMA Grand Master 2.6 – User’s Guide 7 Troubleshooting TMA Grand Master 7 Troubleshooting TMA Grand Master 7.1 Hardware-related issues TMA Grand Master Does Not Work at All What to do: Contact 3DHISTECH support. Error During Initialization (Maintenance issue) Cause: The surface of the tray between the positions F9 and F10 or the touch sensor is contaminated.

  • Page 85: Software-Related Issues

    TMA Grand Master 2.6 – User’s Guide 7 Troubleshooting TMA Grand Master 7.2 Software-related issues Windows 7 Update If Windows 7 Update is launched during working with TMA Grand Master, make sure not to restart Windows 7 after the update process is finished. Follow the below steps to avoid the automatic reboot...
  • Page 86 HDD is inaccessible/not writable The System Administrator must ensure accessibility by the control software to some folders on the computer. For instance, write access must be granted to: C:\ProgramData\3DHISTECH\TMAControl folder, its sub-folders/files, and in addition, enable the software to modify registry logs.
  • Page 87 TMA Grand Master 2.6 – User’s Guide 7 Troubleshooting TMA Grand Master Block image and label area not visible Cause: Problem with preview camera – COM driver registry entry is missing Solution: Restart GTMA software application. If the problem still persists, try to reinstall it.

  • Page 88: Cassette And Block Dimensions

    24 mm (H) x 37 mm (W) x 7.5 mm (D) • NOTE: If using the 3DHISTECH block moulder, the thickness (depth) of the block is 13.5 mm. The smaller size (7.5 mm in depth) means the paraffin thickness from the upper edge of the •...

  • Page 89: Technical Description Of The Hardware

    TMA Grand Master 2.6 – User’s Guide 9 Technical Description of the Hardware 9 Technical Description of the Hardware 9.1 Physical Dimensions and Weight Name of the Unit Dimensions in mm* Weight in kg* (Width x Depth x Height) TMA Grand Master main unit 807×505×444...

  • Page 90: Objective And Cameras

    TMA Grand Master 2.6 – User’s Guide 9 Technical Description of the Hardware 9.3 Objective and Cameras Component Description Objective 16 mm focal length Camera type VR Magic Camera resolution 3,14 Million Pixel 9.4 Ambient Conditions Condition Suitable Range Shipment (packed) Ambient temperature -40°C to +70°C...

  • Page 91: Operating Data

    TMA Grand Master 2.6 – User’s Guide 9 Technical Description of the Hardware 9.5 Operating Data Category of operating environment closed room facilities Electrical protection class Internal protection degree IP 20 Electrical safety in compliance with EN 61010-1 (IEC 61010-1) and taking CSA &...

  • Page 92: Index

    TMA Grand Master 2.6 – User’s Guide Index Index Barcode............................46, 47 Block............................48, 54 Donor block......8, 9, 14, 31, 32, 36, 45, 47, 49, 50, 51, 52, 53, 59, 60, 64, 68, 70, 81, 83 Drill................9, 13, 31, 32, 33, 34, 36, 37, 38, 42, 78, 86, 87 Excel............................14, 68...

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