WARRANTY INFORMATION This manual is a guide for the use of the Bead Ruptor 4 Bead Mill Homogenizing System and accessories. Data herein has been verified and validated. It is believed adequate for the intended use of the instrument. If the instrument or procedures are used for purposes over and above the capabilities specified herein, confirmation of the validity and suitability should be obtained, otherwise Omni International does not guarantee results and assumes no obligation or liability.
Do not attempt to modify any part of the Bead Ruptor 4. If you experience problems with or have questions about your Bead Ruptor 4, contact your authorized dealer or call Omni at 1-800-776-4431 or 770-421-0058.
2.1 UNPACKING THE Bead Ruptor 4 CAUTION: DO NOT lift the Bead Ruptor 4 by holding the lid. It must be lifted by gripping the sides of the unit and holding it from the bottom. 1. Remove the unit from the packaging and set it on its side.
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Plug the Bead Ruptor 4 into the power supply using the supplied power cord. In the event of a malfunction or breakdown, grounding provides a path of least resistance for electric current to reduce the risk of electric shock.
SECTION 2 — UNPACKING THE BEAD RUPTOR 4 2.3 COMPONENTS Prior to operation, please remove all parts from the shipping container and inspect for damaged or missing parts. If any parts are found to be damaged or missing, please contact Omni International at 800.776.4431. DESCRIPTION QUANTITY...
SECTION 3 — BEAD RUPTOR SAMPLE TUBES 3.1 TUBES & TUBE CARRIAGES 4 x 1.5 mL microtubes 1.5 mL Tube Volume and Tissue Size: Minimum: 20 µL, 1 mg Maximum: 1 mL, 1 g 4 x 2 mL or 0.5 mL screw cap tubes (included with BR 12) 2 mL Tube Volume and Tissue Size: Minimum: 300 µL, 1 mg Maximum: 1.8 mL, 1 g...
Polypropylene microtube; 1.5 mL 1000 19-661-1000 RNase, DNase free It is Strongly recommended that only Omni Tubes be used with the Bead Ruptor 4. Other tubes might not be capa- ble of withstanding the forces generated by the Bead Ruptor 4.
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19-650 tube with caps. RNase & DNase free. It is Strongly recommended that only Omni Tubes be used with the Bead Ruptor 4. Other tubes might not be capa- ble of withstanding the forces generated by the Bead Ruptor 4.
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Bead Mix It is strongly recommended that Omni 7 mL Tubes be used in conjunction with the Bead Ruptor 4. Our tests have shown that Omni Tubes are the only tubes available that are capable of withstanding the forces generated by the Bead Ruptor.
SECTION 3 — BEAD RUPTOR SAMPLE TUBES 3.3 IMPORTANT SAMPLE TUBE INFORMATION Dry, fresh or frozen samples can be homogenized with or without buffer using the Bead Ruptor 4 and Bead Ruptor sample tubes. In the event of tube leakage or tube breakage, Omni recommends the following solutions: •...
SECTION 4 — BEAD RUPTOR OPERATION 4.1 LOADING SAMPLE TUBES Users can simultaneously homogenize 1 to 4 samples per run. The user may load tubes in any position for processing. IDENTIFICATION OF PARTS: NOTE: 1.5ml & 2ml tubes use the same Tube Holder. 2 mL Tubes 2 mL Tube Holder 1.
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SECTION 4 — BEAD RUPTOR OPERATION 4.1 LOADING SAMPLE TUBES (cont.) LOADING THE 7 mL ADAPTOR. 7 mL Tubes...
4.3 START UP OF THE EQUIPMENT Turn the Bead Ruptor 4 on by pressing the ON/OFF switch located on the rear panel near the AC power input. A Menu displays the programming mode. Programming mode displays the last program run before power was removed.
Homogenization settings cannot be changed once the run is in progress • The Bead Ruptor 4 is designed for non-stop use and does not require a cool down period between runs. The user can pause or stop a run by pressing the “STOP” button at any time.
SECTION 6 — MAINTENANCE 6.1 CLEANING THE Bead Ruptor 4 The houseing of the unit can be cleaned with a sponge or damp cloth moistened with water or alcohol. WARNING: For safety purposes and to prevent any damage of the unit, the recommendations listed below should be strictly followed: •...
SECTION 7 — TROUBLESHOOTING DO NOT attempt to service the Bead Ruptor 4 in a manner other than those discussed in this manual. For any issue that is unsuccessfully corrected using this guide, please contact your authorized dealer or call Omni International at: 800.776.4431.
SECTION 7 — TROUBLESHOOTING 7.3 CHANGING THE TUBE HOLDER 1. Ensure the unit is powered down and unplugged. (Figure 1) 2. Use the supplied 3 mm allen wrench to loosen the central screw (shown in arrow in figure 2) securing the tube holder to the pivot shaft (figure 2).
SECTION 7 — TROUBLESHOOTING 7.4 CHANGING THE NECK GASKET In the event of damage the neck gasket can be removed and replaced. REQUIRED TOOLS: • 3mm allen wrench • BR 4 neck gasket (P/N 25-130-60) • BR 4 neck gasket restriction ring (P/N 00-725-36) 1.
SECTION 8 — TRANSPORT, STORAGE & SERVICE 8.1 TRANSPORTING THE Bead Ruptor 4 The Bead Ruptor 4 must be shipped in its original packaging. Before transporting the equipment, it is necessary to: 1. Remove all tubes, cover the unit in its plastic bag.
SECTION 8 — TRANSPORT, STORAGE & SERVICE PLEASE NOTE: The Bead Ruptor 4 MUST be shipped in its original packaging. Failure to do so can result in serious damage to the unit and will void all warranties. 8.2 STORAGE The unit can be used in a cold room, but it must be stored in a dry area at a temperature ranging from 0°C/32°F to 50°C/122°F...
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