Roche Cobas C 311 Manual
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Roche Cobas C 311 Manual

Roche Cobas C 311 Manual

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Host Interface Manual
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Mbelu
January 30, 2025

comment lancer un échantillon sur Cobas C311Mamy

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1 comments:
Mr. Anderson
February 10, 2025

To run a sample on the Roche Cobas C 311 analyzer, follow these steps:

1. Prepare the System
- Check the system overview screen for any alerts.
- Ensure reagent inventory is sufficient.
- Perform necessary maintenance and calibration.

2. Load the Sample
- Place the sample in the appropriate position (Routine or STAT).
- Ensure the sample has a valid order in the workflow.

3. Start the Analysis
- Select the sample for processing.
- The system will pipette and analyze the sample automatically.

4. Monitor the Process
- Observe the system for any sampling stop or errors.
- If a sampling stop occurs, verify the sample order and reposition if needed.

5. Review Results
- Check the result records for completion.
- Data is transmitted to the host if configured.

Following these steps ensures smooth operation and accurate results.

This answer is automatically generated

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john lumu
March 11, 2025

why the names cobas c311 and cobas e411

0
2 comments:
Mr. Anderson
March 11, 2025

The Roche Cobas C 311 is a chemistry analyzer used for routine and specialized clinical chemistry testing, providing reliable diagnostic results for healthcare professionals. The Cobas E 411, on the other hand, is not described in detail in the provided context, but based on its naming convention, it is likely an immunoassay analyzer rather than a clinical chemistry analyzer. The key difference is that the Cobas C 311 focuses on chemistry assays, while the Cobas E 411 is likely used for immunoassay testing.

This answer is automatically generated

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JOHN LUMU
March 20, 2025

@Mr. Anderson

0
Bulegyeya Aniziyo
April 2, 2025

how to run qcs

0
1 comments:
Mr. Anderson
April 2, 2025

To run quality control (QC) samples on the Roche Cobas C 311:

1. Use the system screen to program QC for all reagents on board, including any standby packs.
2. Print the QC load list, which shows what QC materials are needed and where to load them.
3. Ensure reagents are loaded and the system is ready.
4. Run the automated maintenance using a daily pipe, which can include QC-related tasks.
5. If applicable, include wash steps for drugs of abuse tests.

These steps help ensure QC samples are processed correctly.

This answer is automatically generated

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Summary of Contents for Roche Cobas C 311

  • Page 1 311 analyzer Host Interface Manual New Mode...
  • Page 2 In no case shall Roche Diagnostics be liable for incidental or consequential damages. The contents of this manual, including all graphics and photographs, are the property of Roche Diagnostics.
  • Page 3 Roche/Hitachi cobas c 311 analyzer trademarks of Roche. All other trademarks are the property of their respective owners. Roche Diagnostics May 2011 Host Interface Manual – Version 1.3...
  • Page 4 Roche/Hitachi cobas c 311 analyzer Table of contents Revision history Table of contents Overview Part Specification of interface Part Specification of communication Host communication setting Communication cable Communication text Part Communication text ASTM communication protocol Part Communication data structure Frame structure...
  • Page 5 Overview...
  • Page 6 This document describes communication procedure related to communication method that enables intercommunication between Laboratory Host System, hereinafter referred to as HOST, and cobas c 311 analyzer. Specification and software described herein comply with the following ASTM communication protocol: (HOST communication ASTM...
  • Page 7 Specification of interface Specification of communication .......... B-2 Host communication setting ..........B-3 Communication cable............B-9...
  • Page 8 Roche/Hitachi cobas c 311 analyzer Specification of interface Specification of Communication Specification of Interface Communication between cobas c 311 analyzer and HOST is based on RS-232C connection. Specification of Communication Specification of serial interface is shown as follows: Table B-1 Specification of Serial Interface...
  • Page 9 Roche/Hitachi cobas c 311 analyzer Specification of interface Host Communication Setting Host Communication Setting Select “Yes/No” at “Host Communication” on Start Conditions screen. Select condition of HOST communication on [Utility]- [System]-[Host Communication Setting] window. The setting is only changeable when “Host Communication” is off.
  • Page 10 Roche/Hitachi cobas c 311 analyzer Specification of interface Host Communication Setting Roche Diagnostics May 2011 Host Interface Manual – Version 1.3...
  • Page 11 Roche/Hitachi cobas c 311 analyzer Specification of interface Host Communication Setting Roche Diagnostics May 2011 Host Interface Manual – Version 1.3...
  • Page 12 Roche/Hitachi cobas c 311 analyzer Specification of interface Host Communication Setting Transfer parameters are shown in Table B-3. Table B-3 Transfer Parameters List Parameter Option Communication Setting RS232C Setting Speed 19200/9600/4800 Select speed. Parity Select Parity. 7bit, EVEN,2Stopbit/ 7bit, ODD,2Stopbit/...
  • Page 13 Roche/Hitachi cobas c 311 analyzer Specification of interface Host Communication Setting Parameter Option Ignore host orders for samples check box On/Off If this funciton is enable, when orders are sent from Host, with already existing 1st results orders for tests with already existing 1st run results are ignored and not measured again.
  • Page 14 ‘***...’ Note Because Host protocol and text field is same as cobas6000, Rack ID field is used in cobas c 311 analyzer communication text. The only currently known use for this function is with a Sample Handling System that ‘manufactures’ sample aliquots for the analyzer.
  • Page 15 Workplace/Data Review screen. Communication Cable Connect RS-232C communication cable to the connector at the cobas c 311 analyzer. The connector is D-SUB9. Fig. B-1 shows connector and communication cable. Fig. B-2 shows connection diagram. Roche Diagnostics May 2011 Host Interface Manual –...
  • Page 16 Roche/Hitachi cobas c 311 analyzer Specification of interface Communication Cable Connector for External Communication Fig. B-1 Connector Host Cable for Hitachi Analyzer Analyzer Fig. B-2 Connection Diagram Roche Diagnostics May 2011 Host Interface Manual – Version 1.3 B-10...
  • Page 17 Communication text Communication text ............C-2...
  • Page 18 Roche/Hitachi cobas c 311 analyzer Communication Text Communication Text Table C-1 shows the communication text of the cobas c 311 analyzer. Table C-1 List of Communication Text cobas type Text Direction Real Time Batch Upload Inquiry for Order cobas c 311->HOST...
  • Page 19 ASTM communication protocol Communication data structure ..........D-2 Frame structure..............D-3 Definition of communication protocol ........D-4...
  • Page 20 Roche/Hitachi cobas c 311 analyzer ASTM communication protocol Communication data structure ASTM Communication Protocol cobas c 311 analyzer employs ASTM communication protocol. Communication data structure ASTM communication protocol consists of three layered data structure such as message, record, and frame. In the application layer, data is communicated by message.
  • Page 21 Roche/Hitachi cobas c 311 analyzer ASTM communication protocol Frame Structure Frame Structure Frame structure is shown below. - Middle frame when a frame is divided into more than one. [STX] text [ETB] [CR] [LF] - When the last frame or a frame is single frame.
  • Page 22 Response is generated after the information is sent. Response is not generated simultaneously with communication. Unlike the other communication protocols, it does not have master-slave relation. Both cobas c 311 analyzer and HOST enable to initialize the communication. When establishing send system and receive system, or when...
  • Page 23 These characters are normally sent by using ASCII code 15hex [NAK] when the receiver is busy. The sender waits for a certain length of time, e.g., cobas c 311 analyzer waits for 10 seconds, and tries to establish with the other [ENQ]. The cobas c 311 analyzer repeats this cycle until the number of retries after error reaches six.
  • Page 24 - HOST sends [ACK] or [EOT]. cobas c 311 analyzer sends the next record. cobas c 311 analyzer has data that is to be communicated. cobas c 311 analyzer continues to send records. (It is started with Establish phase.)
  • Page 25 The line is deemed to be neutral status. - HOST sends [EOT]. The cobas c 311 analyzer is turned into idle status. Only completely received frame is deemed to be effective. Termination Phase Both sender and receiver change their status into idle in Termination phase.
  • Page 26 Record structure Syntax ................. E-2 Message header record ............E-7 Message termination record ..........E-8 Request information record..........E-9 Patient information record ..........E-11 Test order record............... E-12 Comment record that follows the order record (used for patient demographic data) ..........E-14 Result record..............
  • Page 27 Roche/Hitachi cobas c 311 analyzer Record structure Syntax Record Structure Syntax Syntax used in message (records) communicated by cobas c 311 analyzer is shown below. Table E-1 Message Syntax Message Syntax Communication Text Real/Batch cobas Type Comment or Special Instructions...
  • Page 28 Roche/Hitachi cobas c 311 analyzer Record structure Syntax Communication sequences (message flow) of communication message by application layer are shown below. (1) Order for Test Request : real-time cobas c 311 analyzer [HOST] Inquiry for the Requested Tests -> (TSREQ^REAL) Order for Test Request <-...
  • Page 29 Roche/Hitachi cobas c 311 analyzer Record structure Syntax ASTM syntax is shown below. (a) Terminating character of record: Indicates completion of record. ASCII CR character (0Dhex) is required. (b) Field separator character = vertical bar ‘ | ’: Separates adjacent fields in record. Also separates the first record ID, the character appeared at the top of record, and the next field.
  • Page 30 Roche/Hitachi cobas c 311 analyzer Record structure Syntax Escape sequences other than the above are skipped and handled as null value. Roche Diagnostics May 2011 Host Interface Manual – Version 1.3...
  • Page 31 Roche/Hitachi cobas c 311 analyzer Record structure Syntax The table below describes attributes of each field in each record shown in chapter 5. Name of Attributes Description Order (No.) Sequence of the field. Sequence of the fields in record. Name of Field (Field) Name of relevant field.
  • Page 32 ‘ABUPL’: Absorbance report ‘RSREQ’: Inquiry for the result <Mode of message> Type: ST Max: 5 ‘REAL’: communication in real time. ‘BATCH’: communication based on request from cobas c 311/HOST. ‘REPLY’: reply to the request. Processing ID ‘P’ fixed. Version No.
  • Page 33 Roche/Hitachi cobas c 311 analyzer Record structure Message Termination Record Message Termination Record cobas type (Upload, Download) L | 1 |N [ C R ] (1) (2) (3) Comments Field Field Type cobas Type Record Type ID ‘L’ fixed. Sequence Number Indicates sequence No.
  • Page 34 <SampleID> Type: ST Max: 22 indicates Sample No. (Sample ID.) <SequenceNo> Type: NM Max: 5 indicates cobas c 311 analyzer internal sequence No. The range is 1-60000 < Rack IDNo> Type: ST Max: 5 indicates carrier No. (Disk/Rack.) At the c311 analyzer, Rack ID contains two kinds of information:...
  • Page 35 Roche/Hitachi cobas c 311 analyzer Record structure Request Information Record Request Information Indicates the objective of the record. Setting is as follows: Status Codes ‘O’: Order query (to Host) ‘A’: Cancel the last request (to Host) ‘F’: The final result...
  • Page 36 Roche/Hitachi cobas c 311 analyzer Record structure Patient Information Record Patient Information Record cobas type (Upload, Download) P|1||||||20070921|M||||||35^Y [ C R ] (1) (2) (3) (4) (5) Comments Field Field Type cobas Type Record Type ID ‘P’ fixed. Sequence Number Indicates sequence No.
  • Page 37 <SampleType>^<ContainerType> <SequenceNo> Type: NM Max: 5 indicates cobas c 311 analyzer. internal sequence No. Confirmation number when samples are numbered in sequence in order of input. In case of QC material, ‘Control Number * 1000+ Sequence No. sample’ is used.
  • Page 38 Indicates order. Repeats up to 100. Setting is as follows: ^^^<ApplicationCode>^<Dilution>\… Repeat \ (delimiter) for multiple test selection. <ApplicationCode> Type: NM Max: 5 indicates cobas c 311 analyzer Host Test No. <Dilution> Type: ST or MN Max: 3 indicates automatic dilution factor. None: not diluted.
  • Page 39 Roche/Hitachi cobas c 311 analyzer Record structure Comment Record, that follows the order record (used for patient demographic data) Comment Record, that follows the order record (used for patient demographic data) cobas type (Upload, Download) C | 1 | I | ······························^HSP1·····················^····················^···············^··········|G...
  • Page 40 Indicates order. ^^^<ApplicationCode>/<Dilution>/<pre-dilution>/… <ApplicationCode> Type: NM Max: 5 indicates cobas c 311 analyzer Host Test No. The analyzer identifies the test with 3-digit numbers. Specify these 3-digit numbers. The range of application code is expanded to 5-digit. Photometrics: 1-910, ISEs: Na=989, K=990, Cl=991...
  • Page 41 ISE11 ISE Test Calculate Test or Not measured test Note: cobas Type transmits calculated tests. Qualitative result format for cobas c 311 analyzer tests can be activated on the Utility/Application/Range screen. Table E-2 Qualitative Analysis Transmission Data Analytical Result Range Transmission Data Analytical Result =<...
  • Page 42 Roche/Hitachi cobas c 311 analyzer Record structure Comment record, that follows the result record (result data flag) Comment record, that follows the result record (result data flag) cobas type (Upload) C | 1 | I | 1 6 | l...
  • Page 43 Roche/Hitachi cobas c 311 analyzer Record structure Photometric Calibration Result Record Photometric Calibration Result Record cobas type (Upload) An example in case that Chemistry Test Calibration Results Detail mode is disabled. M|1|PCR|BMSERV|^^^714|P1|||2782^2805^2839^2860^^\6119^6577^6134^6592^^|[ C R ] (1)(2)(3) (4) (6) (7)(8) (9) An example in case that Chemistry Test Calibration Results Detail mode is enabled.
  • Page 44 Roche/Hitachi cobas c 311 analyzer Record structure Photometric Calibration Result Record (12) Expired Flag Expired Flag 0:Calibration performed with “Not Expired Bottle” 1:Calibration performed with “Expired Bottle” This data is sent to the host only when an option of “Chemistry Test Calibration Result Detail”...
  • Page 45 Roche/Hitachi cobas c 311 analyzer Record structure ISE Calibration Result Record ISE Calibration Result Record cobas type (Upload) M|1|ICR|adm···|ISE11||||^^^^^^^|^^^^^^^|^^^^^^^|-32.4^-35.1^-28.1 (1)(2)(3) (4) (5)(6)(7)(8)(9) (10) (11) (12) ^-32.2^56.0^134.2^135.2^-0. 7|-34.9^-46.3^-25.8^-33.7^55.7^4.8^5 (13) .04^-0.06|121.4^125.8^118.4^121.9^-42.0^102.0^99.5^-3.7 [ C R ] (14) Comments Field Field Type cobas Type Record Type ID Use ‘M’.
  • Page 46 Roche/Hitachi cobas c 311 analyzer Record structure Photometric Absorbance Data Record Photometric Absorbance Data Record cobas type (Upload) M|1|ABS|P1|1||10|50|0\1497\1499\1499|13140\12828\12760\12699 (1)(2)(3)(4) (5) (6) (7) \12646\12605\12571\12545\12526\12504\12495\12481\12474\12472\124 65\12463\12459\12454\12453\12449\12448\12442\12594\12986\12993 \12992\12987\12987\12980\12982\12975\12973\12974\12970\12972\129 70\12969\12969\12965\12970\12966\12970\12971\12974\12972\12977\1 2976\12982 [ C R ] Comments Field Field Type cobas Type Record Type ID Use ‘M’.
  • Page 47 Roche/Hitachi cobas c 311 analyzer Record structure List of result data flags List of result data flags Table E-3 Data Alarm List Alarm Alarm Result Photo- Printer Screen Host code Data metry no alarm ADC abnormal ADC.E ADC.E Cell blank abnormal >Cuvet...
  • Page 48 Roche/Hitachi cobas c 311 analyzer Record structure List of result data flags [Result Data] In case a column of “Result Data” is blank, result is output as value. In case a column of “Result Data” is “SPACE”, result is output as space.
  • Page 49 Communication trace Test selection information in real time ........ F-2 Real time test results............F-3 Batch test selection information .......... F-4...
  • Page 50 Sequence No communicated from cobas c 311 analyzer may not be sequential number depending on cobas c 311 analyzer status. As they are different from on-line sample No. (work sheet operation), Sequence No is not allowed to be on-lined for key information.
  • Page 51 Communication trace Real Time Test Results Real Time Test Results (1) When the result value is within normal range. cobas c 311 analyzer sends test result of sample ID=000004, sequence No.=40, and Position=5. H|\^&|||cobas c 311^1|||||host|RSUPL^REAL|P|1 [CR] [ C R ]...
  • Page 52 Roche/Hitachi cobas c 311 analyzer Communication trace Batch Test Selection Information (4) When it is a control sample. H|\^&|||cobas c 311^1|||||host|RSUPL^REAL|P|1 [CR] [ C R ] O|1| 17222200 |10096^30085^0 85^^QC ^SC |^^^672^|||||||Q||||1 |||||||20051220104418|||F C |1 |I | ^ ^ [ C R ] ^^|G R |1 | ^ ^ ^1 0 / | 1 .2 6 |u l U /m L ||L | | F | |a d m i n | | | P1...
  • Page 53 Appendix Instrument Alarms ...............G-2 ASCII Table.................G-9...
  • Page 54 Roche/Hitachi cobas c 311 analyzer Appendix A - Instrument Alarms Instrument Alarm List Appendix A - Instrument Alarms Instrument Alarm List Alarm Type Alarm No Alarm Message Alarm Description Alarm Remedy Abnormal Receiving Text Abnormal Text has been received from Host.
  • Page 55 Roche/Hitachi cobas c 311 analyzer Appendix A - Instrument Alarms Instrument Alarm List Alarm Type Alarm No Alarm Message Alarm Description Alarm Remedy Abnormal TS from Host Received request for serum index test is Check the host computer. Is it ON? wrong.
  • Page 56 Roche/Hitachi cobas c 311 analyzer Appendix A - Instrument Alarms Instrument Alarm List Alarm Type Alarm No Alarm Message Alarm Description Alarm Remedy Abnormal Automatic Received comment even though the mode was Check the host computer. Is it ON? Rerun TS from Host set for no transmission of comments.
  • Page 57 Roche/Hitachi cobas c 311 analyzer Appendix A - Instrument Alarms Instrument Alarm List Alarm Type Alarm No Alarm Message Alarm Description Alarm Remedy Host Communication When the analyzer has received <ACK> or Check the host computer. Is it ON? Error <NAK>...
  • Page 58 Roche/Hitachi cobas c 311 analyzer Appendix A - Instrument Alarms Instrument Alarm List Alarm Type Alarm No Alarm Message Alarm Description Alarm Remedy Host Communication No valid Record. Check the host computer. Is it ON? Error Verify Host Communication on Start Conditions.
  • Page 59 Roche/Hitachi cobas c 311 analyzer Appendix A - Instrument Alarms Instrument Alarm List Alarm Type Alarm No Alarm Message Alarm Description Alarm Remedy Host Receiving Text Error Request Information Status Code is not Please check Request Information Status. effective value.
  • Page 60 Roche/Hitachi cobas c 311 analyzer Appendix A - Instrument Alarms Instrument Alarm List Alarm Type Alarm No Alarm Message Alarm Description Alarm Remedy Host Receiving Text Error Application Code is outside the range. Please check Application Code. Host Receiving Text Error Sample Volume is outside the range.
  • Page 61 Roche/Hitachi cobas c 311 analyzer Appendix B: ASCII Table Control Characters Appendix B: ASCII Table Control Characters Binary Dec Hex abbreviation Description 0000 0000 0 Null character 0000 0001 1 Start of Header 0000 0010 2 Start of Text 0000 0011 3...
  • Page 62 Roche/Hitachi cobas c 311 analyzer Appendix B: ASCII Table Printable Characters Printable Characters Binary Char Binary Char Binary Char 0010 0000 blank 0100 0000 0110 0000 0010 0001 0100 0001 0110 0001 0010 0010 " 0100 0010 0110 0010 0010 0011...

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