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Instruction Manual
Alfa Laval Pharma-line S
5300-0001
ESE02599-EN3
2016-07
Original manual
www.sks-online.com
www.sks-webshop.com

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Summary of Contents for Alfa Laval Pharma-line S 1

  • Page 1 Instruction Manual Alfa Laval Pharma-line S 5300-0001 ESE02599-EN3 2016-07 Original manual www.sks-online.com www.sks-webshop.com...
  • Page 2 www.sks-online.com www.sks-webshop.com...
  • Page 3: Table Of Contents

    4.3. Disassembly for inspection or cleaning ............4.4. Locating leaks ..................4.5. Cleaning the heat exchanger ..............4.6. Gasket replacement ................5. Technical data ..................5.1. Technical data ..................6. Spare Parts ..................... 6.1. Alfa Laval Pharma-line S ................. www.sks-online.com www.sks-webshop.com...
  • Page 4: Description

    - At the end of use, the equipment should be recycled according to relevant, local regulations. Besides the equipment itself, any hazardous residues from the process liquid must be considered and dealt with in a proper manner. When in doubt, or in the absence of local regulations, please contact your local Alfa Laval sales company. www.sks-online.com...
  • Page 5: Application

    1.3 Application The Alfa Laval Pharma-line S is a high quality, double tube sheet shell & tube heat exchanger designed for the pharmaceutical and biotechnology industries. The Pharma-line S is used in pharmaceutical water systems: Water For Injection (WFI), Purified Water (PW), and for heating or cooling of pharmaceutical products.
  • Page 6: Design

    1 Description 1.4 Design The Pharma-line S is in hygienic design in line with ASME BPE, USP and cGMP requirements. The Pharma-line S has no dead-legs and is fully drainable on the product side. All product wetted parts in the Pharma-line S are mechanically polished to Ra <0.5 µm or electropolished to Ra >0.4 µm.
  • Page 7 1 Description Working principles In the Pharma-line S, the risk of mixing between the product and the heating or cooling (service) medium is eliminated as a result of the double tube sheet design. The product flows in the tubes while the service medium flows in a cross flow around the tubes, inside the shell.
  • Page 8: Installation

    2 Installation The Alfa Laval Pharma-line S can be installed either horizontally or vertically, on the floor, on the wall or in the ceiling. The flexible legs on Pharma-line S facilitate easy installation, either it is horizontally or vertically. For easy installation, lifting lugs are fastened to the unit with screws. Before lifting, make sure the lifting lugs are properly secured.
  • Page 9: Levelling

    2 Installation 2.4 Levelling The heat exchanger must be set so that pipe connections can be made without forcing them. However, small forces may be unavoidable. Acceptable forces are as follows: - acceptable forces in all directions on the tube side are max 50 N - acceptable forces in all directions on the shell side are max 100 N 2.5 Cleanliness provisions Connector protectors...
  • Page 10: Fitting And Piping

    2 Installation 2.7 Fitting and piping Bypass valves It may be desirable for the user to provide valves and bypasses in the piping system to enable inspection and repairs. Test connections It may be desirable for the user to install a thermometer well and pressure gauge connections close to the exchanger. Vents and drains It may be desirable for the user to install vent and/or drain valves close to the heat exchanger.
  • Page 11: Operation

    3 Operation 3.1 Design and operating conditions The heat exchanger must not be operated under conditions, which exceed those specified on the name plate. Warning! Failure to operate the heat exchanger within the design pressure and temperature specified on the name plate may result in damage to the heat exchanger and potential injury to adjacent personnel.
  • Page 12: Shut-Down Operation

    3 Operation 3.2.3 Shut-down operation The heat exchanger must be shut down in a manner that minimises different expansions between shell and tubes. If the system will be shut down for a shorter period, make sure the unit is filled up with water completely and no air is available in the system.
  • Page 13: Maintenance

    4 Maintenance 4.1 Inspection At regular intervals and as frequently as experience indicates, an examination should be made of the interior and exterior condition of the unit. Failure to keep all tubes clean may result in decreased performance of the heat exchanger. 4.2 Indication of fouling Heat exchangers subject to fouling or scaling should be cleaned periodically.
  • Page 14: Technical Data

    Standard units, measurements (approximate) [mm] Nozzle size Shell OD Nozzles size Type (mm) Flange Tube Pharma-line S 1 [mm] Pharma-line S 1 - 0.1 1” DN50 1150 1” DN50 1150 Pharma-line S 1 - 0.3 Pharma-line S 1 - 0.4 1”...
  • Page 15 5 Technical data Nozzle schedule Facing Item Service Standard and dimension Tube inlet NAC plate for Tri-clamp Suitable for ASME BPE Tube outlet NAC plate for Tri-clamp Suitable for ASME BPE Shell inlet Weld neck flange DIN2635/EN1092-1 Shell outlet Weld neck flange DIN2635/EN1092-1 www.sks-online.com www.sks-webshop.com...
  • Page 16: Spare Parts

    Gaskets and plate flanges are available as a spare part for Pharma-line S. Replacement gaskets should be purchased in the material originally provided with your heat exchanger. When ordering replacement gaskets or plate flange, please refer to the item No. in the spare part list for Pharma-line S. 6.1 Alfa Laval Pharma-line S 5300-0012 www.sks-online.com...
  • Page 17 6 Spare Parts Gaskets and plate flanges are available as a spare part for Pharma-line S. Replacement gaskets should be purchased in the material originally provided with your heat exchanger. When ordering replacement gaskets or plate flange, please refer to the item No.
  • Page 18 © Alfa Laval Corporate AB This document and its contents is owned by Alfa Laval Corporate AB and protected by laws governing intellectual property and thereto related rights. It is the responsibility of the user of this document to comply with all applicable intellectual property laws. Without limiting any rights related to this document, no part of this document may be copied, reproduced or transmitted in any form or by any means (electronic, mechanical, photocopying, recording, or otherwise), or for any purpose, without the expressed permission of Alfa Laval Corporate AB.

This manual is also suitable for:

Pharma-line s 2Pharma-line s 3

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