Buchi Lyovapor L-300 Operation Manual
  1. Manuals
  2. Brands
  3. Buchi Manuals
  4. Laboratory Equipment
  5. Lyovapor L-300
  6. Operation manual
Buchi Lyovapor L-300 Operation Manual

Buchi Lyovapor L-300 Operation Manual

Hide thumbs Also See for Lyovapor L-300:
Table of Contents

Advertisement

Quick Links

TM
Lyovapor
L-300
Operation Manual

Advertisement

Table of Contents
loading

Related Manuals for Buchi Lyovapor L-300

Summary of Contents for Buchi Lyovapor L-300

  • Page 1 Lyovapor L-300 Operation Manual...
  • Page 2 CH-9230 Flawil 1 E-Mail: quality@buchi.com BUCHI reserves the right to make changes to the manual as deemed necessary in the light of experi- ence, especially with respect to structure, illustrations and technical details. This manual is copyrighted. Information from it may neither be reproduced, distributed, or used for com- petitive purposes, nor made available to third parties.

  • Page 3: Table Of Contents

    BÜCHI Labortechnik AG Contents Table of contents About this document...................... 7 Warning notices in this document...................... 7 Symbols ...............................  7 1.2.1 Warning symbols ........................ 7 1.2.2 Mandatory directive symbols .................... 8 1.2.3 Other symbols..........................  8 Available languages.......................... 8 Trademarks............................ 8 Connected devices .......................... 8 Safety............................ 9 Proper use ............................
  • Page 4 Contents BÜCHI Labortechnik AG Installation.......................... 21 Installation site ...........................  21 Putting the instrument in operation .................... 22 5.2.1 Preparing the instrument...................... 22 5.2.2 Establishing electrical connections .................. 22 5.2.3 Fitting the fresh water connections .................. 23 5.2.4 Fitting the drain tubes ...................... 24 5.2.5 Connecting the coolant ......................
  • Page 5 Connecting the instrument to the LAN.................... 77 Requirements for local network settings....................  77 Assigning a dynamic IP address...................... 77 Enabling the control panel on the BUCHI Cloud................ 77 Downloading the BUCHI Monitor app.................... 77 Layout of BUCHI Monitor app...................... 78 Connecting the instrument and app using a QR code ...............
  • Page 6 Contents BÜCHI Labortechnik AG Cleaning and servicing ..................... 83 Regular maintenance work ........................  83 Performing a vacuum test........................ 84 Performing a leak test........................ 84 Help with faults ........................ 87 10.1 Troubleshooting .......................... 87 10.2 Faults, possible causes and remedies.................... 87 Taking out of service and disposal..................  88 11.1 Disposal .............................

  • Page 7: About This Document

    BÜCHI Labortechnik AG Customer Service. Contact details for your local agents can be found on the back cover of these operating instructions or on the In- ternet at http://www.buchi.com. Warning notices in this document Warning notices warn you of dangers that can occur when handling the device. There are four danger levels, each identifiable by the signal word used.

  • Page 8: Mandatory Directive Symbols

    These operating instructions were originally produced in German and have been translated into several other languages. The translations are available on the en- closed CD or can be obtained as a PDF file via http://www.buchi.com. Trademarks Product names and registered or unregistered trademarks that are used in this in- struction manual are used only for identification and remain the property of the owner in each case.

  • Page 9: Safety

    BÜCHI Labortechnik AG Safety | 2 Safety Proper use The Lyovapor™ L-300 is used for freeze-drying solid materials in ampoules, vials, trays, round-neck or wide-neck flasks and is exclusively intended for that purpose. The Lyovapor™ L-300 can be used in laboratories for the following tasks: —...

  • Page 10: Location Of Warning Signs On The Product

    — Safety-related incidents that occur while using the device should be reported to the manufacturer (quality@buchi.com). BUCHI service technicians Service technicians authorized by BUCHI have attended special training courses and are authorized by BÜCHI Labortechnik AG to carry out special servicing and repair measures.

  • Page 11: Faults During Operation

    Technical modifications to the device or accessories should only be carried out with the prior written approval of BÜCHI Labortechnik AG and only by authorized BUCHI technicians. BUCHI accepts no liability whatsoever for damage arising as a result of unauthorized modifications. Operation Manual Lyovapor...

  • Page 12: Product Description

    3 | Product description BÜCHI Labortechnik AG Product description Description of function The Lyovapor™ is a freeze-dryer in which frozen samples can be gently dried. The basis of freeze-drying is sublimation. Sublimation refers to the process whereby a substance transforms directly from the solid to the gaseous state. The physical process of sublimation can be explained using the solvent water as an example.

  • Page 13: Secondary-Drying Phase

    BÜCHI Labortechnik AG Product description | 3 Controlling the heat transfer prevents the following critical temperatures for amor- phous and crystalline materials being reached: — the glass transition temperature T ' of the frozen sample. — the collapse temperature T —...

  • Page 14: Configuration

    3 | Product description BÜCHI Labortechnik AG Configuration 3.2.1 Front View Fig. 2: Front view 1 Connections for heatable shelves 2 Intermediate valve (Lyovapor™ L-300 Pro only) 3 Ice condenser 4 Optional mounting position for control panel 5 Ventilation slots 6 Castors 7 Castor brake 8 On/Off master switch 9 Control panel...

  • Page 15: Rear View

    BÜCHI Labortechnik AG Product description | 3 3.2.2 Rear view Fig. 3: Rear view 1 Power isolating switch 2 Type plate/Refrigerant specifications 3 Connections for pressure sensors 4 Side connections (option) 5 Connection for fresh water 6 Connection for condensate drain hose I 7 Connection for condensate drain 8 Ventilation slots...

  • Page 16: Control Panel

    3 | Product description BÜCHI Labortechnik AG 3.2.3 Side connections Fig. 4: Side connections 1 Connection for pressure sensor 2 Connection for pressure sensor (option) (option) 3 Automatic stoppering connection 4 Connection for fresh water sensor 5 Connection for receiving vessel sen- 6 Connection for external pressure sen- sors (option)

  • Page 17: Pro Control Panel

    Fig. 6: Pro control panel 1 Touch-screen display 2 Navigation control Type plate The type plate identifies the instrument. The type plate is located at the rear of the in- strument. Buchi Labortechnik AG 9230 Flawil / Switzerland Type: L-xxx 10xxxxxxxx Volt: xxx-xxx VAC Frequ.:...

  • Page 18: Specifications Supplied

    3 | Product description BÜCHI Labortechnik AG Type: L-xxx xxHz Cooling System Refrigerant: Rxxx Filling: xxx g Global Warming Potential (GWP): xx tCO Fig. 8: Refrigerant details 1 Instrument name 2 Refrigerant details 3 Filling capacity 4 Global warming potential Specifications supplied NOTE The scope of delivery depends of the configuration of the purchase order.

  • Page 19: Ambient Conditions

    BÜCHI Labortechnik AG Product description | 3 Specification L-300 for 50Hz L-300 for 60Hz Overvoltage category Protection rating IP20 IP20 Pollution degree Inlet water temperature 15 - 20 °C 15 - 20 °C Inert gas pressure max. 2 bar max. 2 bar Water pressure 2 - 5/6 bar 2 - 5/6 bar...

  • Page 20: Transport And Storage

    4 | Transport and storage BÜCHI Labortechnik AG Transport and storage Transport IMPORTANT Risk of breakage due to incorrect transportation Make sure that the instrument is fully dismantled. Pack every instrument components properly to prevent breakage. Use the original packaging whenever possible. Avoid sharp movements during transit.

  • Page 21: Installation

    BÜCHI Labortechnik AG Installation | 5 Installation Installation site The installation site must meet the following requirements: DANGER Risk of explosion from flammable gas-and-air mixtures The potential consequences are death or extremely serious injury. Do not damage the refrigerant circuit piping. Store and operate the instrument in a room with a volume of at least 16.6 m that an ignitable gas-and-air mixture cannot develop.

  • Page 22: Putting The Instrument In Operation

    5 | Installation BÜCHI Labortechnik AG Fig. 9: Castor brake NOTE Make sure that the power supply can be disconnected at any time in an emergency. NOTE Depending on the ambient conditions, condensation may form on any cold surface on the unit. Putting the instrument in operation IMPORTANT Instrument damaged if restarted too early...

  • Page 23: Fitting The Fresh Water Connections

    BÜCHI Labortechnik AG Installation | 5 3. Be equipped with suitable fuses and electrical safety features. 4. Be equipped with a proper earthing. Make sure that all connected devices are earthed. Make sure that the power plug is freely accessible at all times. Insert the power plug into the power socket.

  • Page 24: Fitting The Drain Tubes

    5 | Installation BÜCHI Labortechnik AG Fit the inlet tube (4) onto the connection marked Fresh Water (5). Fix the inlet tube in place with a hose clip. 5.2.4 Fitting the drain tubes CAUTION Risk of scalding by hot water Make sure the condensate drain hose is not loose.

  • Page 25: Connecting The Coolant

    BÜCHI Labortechnik AG Installation | 5 5.2.5 Connecting the coolant Fig. 12: Connecting the coolant 1 Coolant inlet connection 2 Coolant outlet connection 3 Drain tube 4 Inlet tube Precondition: R The coolant connection complies with the specified parameters. See Chapter 3.6 "Technical data", page 18 Make sure that the instrument is not connected to the power supply.
  • Page 26 5 | Installation BÜCHI Labortechnik AG Fig. 13: Fitting the pressure sensors 1 Cartridge pressure sensor 2 Cartridge pressure sensor 3 Clamp, ISO-KF 16 4 Clamp, ISO-KF 16 5 Seal, ISO-KF 16 6 Connection for pressure sensor 7 Seal, ISO-KF 16 8 Connection for pressure sensor 9 Connection 10 Connection...

  • Page 27: Commissioning The Vacuum Pump

    BÜCHI Labortechnik AG Installation | 5 Commissioning the vacuum pump The vacuum pump evacuates the top-mount drying rack during the freeze-drying process. NOTE To increase the service life of the vacuum pump, operate the vacuum pump with an open gas ballast valve. NOTE Prepare the vacuum pump according to the manufacturer's instructions.

  • Page 28: Fitting The Acrylic Drying Chamber

    5 | Installation BÜCHI Labortechnik AG Fig. 15: Fitting the 300 mm dia. O-ring 1 Groove above ice condenser 2 O-ring, dia. 300 mm Make sure that the groove above the ice condenser (1) is clean, free of dust and not scratched. Check the 300 mm dia. O-ring (2) for damage and grease it with vacuum grease. Place the 300 mm dia.

  • Page 29: Fitting The Manifold Acrylic Drying Chamber

    BÜCHI Labortechnik AG Installation | 5 Fig. 16: Fitting the acrylic drying chamber 1 Cover 2 O-ring, dia. 300 mm 3 Cylinder 4 Intermediate plate 5 Ice condenser 6 Rack Precondition: R The 300 mm O-ring is fitted in the groove above the ice condenser. Remove all parts of the drying chamber from the packaging and check for dam- age.

  • Page 30: Fitting The Stopper Acrylic Drying Chamber

    5 | Installation BÜCHI Labortechnik AG Fig. 17: Fitting the manifold acrylic drying chamber 1 Cover 2 O-ring, dia. 300 mm 3 Cylinder 4 Intermediate plate 5 Ice condenser 6 Rack Precondition: R The 300 mm O-ring is fitted in the groove above the ice condenser. Remove all parts of the drying chamber from the packaging and check for dam- age.
  • Page 31 BÜCHI Labortechnik AG Installation | 5 Fig. 18: Fitting the stopper acrylic drying chamber 1 Hand wheel 2 Cover 3 O-ring, dia. 300 mm 4 Cylinder 5 Springs 6 Ice condenser 7 Intermediate plate 8 Rack 9 Hook Precondition: R The 300 mm O-ring is fitted in the groove above the ice condenser. Remove all parts of the drying chamber from the packaging and check for dam- age.

  • Page 32: Fitting Heatable Shelves

    5 | Installation BÜCHI Labortechnik AG 5.4.5 Fitting heatable shelves Shelves can be fitted in the drying chambers. The shelves allow the freeze-drying of samples in vials or as loose samples. The shelves slide into a rack inside the drying chamber.
  • Page 33 BÜCHI Labortechnik AG Installation | 5 Sliding the shelves into the rack Fig. 20: Heatable shelf in rack 1 Rack 2 Slot for shelf 3 Temperature sensor (option) 4 Stop 5 Connections for shelves 6 Electrical connector for heatable shelf 7 Heatable shelf 8 Lug Precondition: R The rack is mounted on top of the ice condenser.
  • Page 34 5 | Installation BÜCHI Labortechnik AG Plugging in the heatable shelf connector Fig. 21: Plugging in heatable shelf 1 Electrical connector for heatable shelf 2 Connections for shelves 3 Ring Precondition: R The shelf is slotted into the rack. Push the electrical connector (1) onto one of the shelf connections (2) while simul- taneously twisting the ring (3) anti-clockwise.

  • Page 35: Fitting The Non-Heatable Shelf

    BÜCHI Labortechnik AG Installation | 5 Temperature sensor connector 6 5 4 Fig. 23: Temperature sensor connector 1 Heatable shelf 2 Connection for temperature sensor 3 Marking on temperature sensor con- 4 Marking on temperature sensor con- nection nector 5 Ring 6 Temperature sensor connector 7 Temperature sensor Plugging in the temperature sensor connector:...
  • Page 36 5 | Installation BÜCHI Labortechnik AG Fig. 24: Non-heatable shelf 1 Non-heatable shelf Sliding the shelves into the rack Fig. 25: Non-heatable shelf in rack 1 Rack 2 Slot for shelf 3 Stop 4 Connections for shelves 5 Non-heatable shelf 6 Lug Precondition: R The rack is mounted on top of the ice condenser.

  • Page 37: Assembling The Manifold Drying Rack

    BÜCHI Labortechnik AG Installation | 5 Slide the shelf (5) into a slot (2) in the rack (1). Make sure that the shelf (5) is secured by the lug (6). Fit the cylinder and the lid. 5.4.7 Assembling the manifold drying rack The instrument can be completed with a manifold drying rack.
  • Page 38 5 | Installation BÜCHI Labortechnik AG Fig. 27: Fitting manifold valves 1 Connection on the top-mount drying 2 Manifold valve rack Remove manifold valve (2) from the packaging. Fit manifold valve (2) onto the connection on the top-mount drying rack (1). Manifold valve settings The lever on a manifold valve can be set to the following positions: Fig. 28: Manifold valve...
  • Page 39 BÜCHI Labortechnik AG Installation | 5 Fig. 29: Evacuation adaptor 1 Manifold valve 2 Lever 3 Evacuation adaptor 4 Tube clip 5 Vacuum tubing Precondition: R The manifold valve is closed. Fit the evacuation adaptor (3) onto the lever (2). Fit the vacuum tube (5) onto the evacuation adaptor (3). Fix the vacuum tube with the tube clip (4).

  • Page 40: Gas Connections (Option)

    5 | Installation BÜCHI Labortechnik AG Gas connections (option) 5.5.1 Fitting an air filter (option) Fig. 30: Fitting an air filter 1 Air filter 2 Tube clip 3 Tubing 4 Tube clip 5 Gas connection for pressure regulat- 6 Gas connection for venting valve ing valve 7 Tube clip 8 Tubing...

  • Page 41: Connecting Inert Gas (Option)

    BÜCHI Labortechnik AG Installation | 5 5.5.2 Connecting inert gas (option) Fig. 31: Connecting inert gas 1 Inert gas tube 2 Tube clip 3 Gas connection for pressure regulat- 4 Gas connection for venting valve ing valve 5 Tube clip 6 Inert gas tube Connecting the inert gas to the pressure regulating valve Switch the On/Off master switch to Off.

  • Page 42: Operating The Control Panel

    6 | Operating the control panel BÜCHI Labortechnik AG Operating the control panel This section describes the operation of the instrument using the control panel. CAUTION Risk of injury from glass splinters Sharp objects can damage the display. Keep sharp objects away from the display. Layout of the control panel Fig. 32: Layout of the control panel Description...

  • Page 43: Menu Bar

    BÜCHI Labortechnik AG Operating the control panel | 6 General function buttons Symbol Description Meaning [Back] The display reverts to the previous view. [Cancel] Cancels an operation. [Add to favourites] Adds the selected item to the [Favourites] menu. [Remove from Removes the selected item from the favourites] [Favourites] menu.

  • Page 44: Start Menu

    6 | Operating the control panel BÜCHI Labortechnik AG Menu Meaning Submenu/Action symbol [Configuration] menu — Process settings — Settings — Servicing — Service — System information — Notifications [Messages] menu — Logbook 6.3.1 Start menu On the [Start] menu, parameters can be set manually. Changing parameters Select a parameter by turning the navigation control.
  • Page 45 Option Explanation [Mobile connec- View The control panel shows a password tion password] for entry in the BUCHI Monitor app. [Mobile connec- View The control unit shows a QR code tion QR code] for reading by the BUCHI Monitor app.
  • Page 46 [Vacuum test] Perform vacuum test See Chapter 9.2 "Performing a vac- uum test", page 84 Submenu Service The submenu [Service] is for BUCHI service technicians only. Action Option Explanation [Refrigerant cir- View The following information on the re-...
  • Page 47 BÜCHI Labortechnik AG Operating the control panel | 6 Action Option Explanation [Vacuum sys- View The following information on the vac- tem] uum system is available: — Pump hours of duty — Pump oil hours of duty — Pressure in ice condenser 1 —...
  • Page 48 6 | Operating the control panel BÜCHI Labortechnik AG Submenu System Information The submenu [System information] contains details of the connected components and information on network connection diagnosis. Action Option Explanation [Control panel] View The following information on the control panel is available: —...

  • Page 49: Status Bar

    The current parameters of the freeze-drying process are being re-established. Symbols on the status bar Symbol Status The instrument is connected to the BUCHI Cloud. The instrument is defrosting. The instrument is starting up. The instrument is in energy-saving mode. Operation Manual Lyovapor...

  • Page 50: Carrying Out Freeze-Drying

    6 | Operating the control panel BÜCHI Labortechnik AG Symbol Status Before the freeze-drying process: Load the top-mount drying rack with a frozen sample. After the freeze-drying process: Remove the dried sample from the top-mount drying rack. The vacuum pump is being brought up to operat- ing temperature.

  • Page 51: Editing Parameters While The Process Is Running

    BÜCHI Labortechnik AG Operating the control panel | 6 Fit a top-mount drying rack. See Chapter 5.4 "Assembling the drying attachments", page 27. Load the top-mount drying rack with frozen preparations. Navigate to the [Start] menu via the navigation path. Enter the required settings for the process parameters. Tap the function [Start] on the function bar.
  • Page 52 6 | Operating the control panel BÜCHI Labortechnik AG Tap the function [Shut down] on the function bar. The instrument is shutting down. The status bar shows the remaining time and the status Shutting down. After the instrument has shut down, the status bar shows the remaining time and the status Defrosting.

  • Page 53: Operating Pro Control Panel

    BÜCHI Labortechnik AG Operating Pro control panel | 7 Operating Pro control panel This section describes the operation of the instrument using the Pro control panel. CAUTION Risk of injury from glass splinters Sharp objects can damage the display. Keep sharp objects away from the display. Layout of Pro control panel Fig. 33: Layout of Pro control panel Description...
  • Page 54 7 | Operating Pro control panel BÜCHI Labortechnik AG Symbol Description Meaning [Cancel] Cancels an operation. [Add to favourites] Adds the selected item to the [Favourites] menu. [Remove from Removes the selected item from the favourites] [Favourites] menu. [Confirm] Confirms an entry. [Edit] Allows the selected item to be edited.

  • Page 55: Menu Bar

    BÜCHI Labortechnik AG Operating Pro control panel | 7 Menu bar The menus are represented by symbols on the menu bar. Navigation through the menus is by the input controls. The following menus are available: Menu Meaning Submenu/Action symbol — Process control parameters Start menu —...

  • Page 56: Method Menu

    Option Explanation [Mobile connec- View The control panel shows a password tion password] for entry in the BUCHI Monitor app. [Mobile connec- View The control unit shows a QR code tion QR code] for reading by the BUCHI Monitor app.
  • Page 57 Display illumination level in %: 0 - ness] [Network] Enter value The following parameters can be edited: Device name/MAC address/DHCP/ System IP address/Subnet mask/ Gateway/DNS server/BUCHI Cloud/ Server IP address [Delete app con- Confirmation question Resets external connections to the nection] instrument. Submenu End point determination...
  • Page 58 Action Option Explanation [Vacuum test] Perform vacuum test See Chapter 9.2 "Performing a vac- uum test", page 84 Submenu Service The submenu [Service] is for BUCHI service technicians only. Action Option Explanation [Refrigerant cir- View The following information on the re- cuit] frigerant circuit is available: —...
  • Page 59 BÜCHI Labortechnik AG Operating Pro control panel | 7 Action Option Explanation [Ice condenser] View The following information on the ice condenser is available: — Steam generator valve — Defrost valve, ice condenser 1 — Defrost valve, ice condenser 2 —...

  • Page 60: Messages Menu

    7 | Operating Pro control panel BÜCHI Labortechnik AG Action Option Explanation [Instrument] View The following information on the L-300 is available: — Serial number — Firmware version — Hours of duty — Status — PCB Temperature — 48V power supply —...
  • Page 61 The instrument is in the course of a freeze-drying process using a method. The instrument is starting up. The instrument is in the course of a manual freeze-drying process. The instrument is connected to the BUCHI Cloud. Operation Manual Lyovapor L-300 61/96...

  • Page 62: Editing A Method

    7 | Operating Pro control panel BÜCHI Labortechnik AG Symbol Status Sample protection is active. Reason: the pressure is outside the pressure lim- its. Sample protection is active. Reason: the temperature is outside the safe tem- perature range. Sample protection is active. Reason: the pressure is outside the pressure lim- its.

  • Page 63: Setting The Sample Collapse Temperature

    BÜCHI Labortechnik AG Operating Pro control panel | 7 Tap the function [Save] on the function bar. The new name is saved. The dialog box closes. 7.5.3 Setting the sample collapse temperature Navigation path ➔ Method Navigate to the [Method] menu via the navigation path. Tap the name of the method that you wish to edit.

  • Page 64: Setting The Steps Of A Method

    7 | Operating Pro control panel BÜCHI Labortechnik AG Tap the function [Save] on the function bar. The setting is saved. The dialog box closes. 7.5.6 Setting the steps of a method The Pro control panel can save up to 30 steps for each method. NOTE The settings for the action Steps affect a single step in each case.

  • Page 65: Setting The Phases Of A Method

    BÜCHI Labortechnik AG Operating Pro control panel | 7 Tap the function [Save] on the function bar. The setting is changed. Adding a step Use the function [Right] or [Left] on the function bar to navigate to the position at which you wish to add a step after the position.
  • Page 66 7 | Operating Pro control panel BÜCHI Labortechnik AG Phase Setting Option Meaning [Primary [Pressure None/Sample None: no action is carried out. drying] action] protection/ Sample protection: if the pressure is Message too high, heating of the shelves is paused. Message: if the pressure is too high, the control panel displays a mes- sage.

  • Page 67: Deleting A Method

    BÜCHI Labortechnik AG Operating Pro control panel | 7 Phase Setting Option Meaning [Stopper- [Pressure Regulated/Min- Regulated: the settings for pressure ing] range] imum and pressure limits are applied. Minimum: the lowest possible vac- uum pressure is applied. [Pressure] Enter value Sets a target value for the regulated pressure.
  • Page 68 7 | Operating Pro control panel BÜCHI Labortechnik AG Navigation path ➔ Method Precondition: R A capacitive pressure sensor (Inficon Porter CDG020D) is connected. R A Pirani pressure sensor (Inficon PSG55x) is connected. Place the alternative pressure sensor in the drying chamber. Navigate to the [Method] menu via the navigation path.

  • Page 69: Temperature Difference Test

    BÜCHI Labortechnik AG Operating Pro control panel | 7 7.7.2 Temperature difference test NOTE The temperature test is successfully completed if all drying shelves are below the threshold. The samples on a drying shelf have different drying times. Take account of the differ- ent drying times in the [Duration] setting.

  • Page 70: Pressure Rise Test

    7 | Operating Pro control panel BÜCHI Labortechnik AG Setting Option Explanation [Continue] Yes/No Yes: the method switches to the next phase. No: the phase is ended when the set levels are reached. [Message] Yes/No The control panel shows or does not show a message as soon as the temperature difference test is passed.

  • Page 71: Performing Freeze-Drying Using A Method [Pro Control Panel]

    BÜCHI Labortechnik AG Operating Pro control panel | 7 Setting Option Explanation [Start condi- Time/Pressure difference test/ Time: The pressure rise test is tion] Temp difference test/Both carried out when the specified time has elapsed. Pressure difference test: The pressure rise test is only carried out if a pressure difference test is passed.

  • Page 72: Starting Freeze-Drying

    7 | Operating Pro control panel BÜCHI Labortechnik AG Navigate to the [Method] menu via the navigation path. Tap the function [Method] on the function bar. Tap the method that you wish to use. Tap the function [Activate] on the function bar. The status bar shows the method activated.

  • Page 73: Changing Parameters While The Process Is Running

    BÜCHI Labortechnik AG Operating Pro control panel | 7 7.8.4 Changing parameters while the process is running NOTE The method parameters can be adjusted while the freeze-drying process is in progress. See Chapter 7.5 "Editing a method", page 62. 7.8.5 Ending freeze-drying Navigation path ➔...

  • Page 74: Starting Freeze-Drying

    7 | Operating Pro control panel BÜCHI Labortechnik AG Tap the function [Start conditioning] on the function bar. The temperature in the ice condenser cools down to operating temperature. The vacuum pump is being brought up to operating temperature. After completion of the conditioning phase, the status bar shows the status Un- load / Load.

  • Page 75: End Point Definition

    BÜCHI Labortechnik AG Operating Pro control panel | 7 7.9.4 End point definition To determine the end point of the freeze-drying process, a pressure rise test can be carried out manually while freeze-drying is in progress. Navigation path ➔ Configuration ➔ End point determination ➔ Pressure rise test Precondition: R The process has been started.

  • Page 76: Mobile Connection

    Notifications keep the user informed of the status of the instrument. Similar to the display on the control panel, the BUCHI Monitor app shows the current settings and actual readings. Depending on the control unit, the BUCHI Monitor app shows either the alphanumeric data only or the data and progression graph (control panel Pro) process.

  • Page 77: Connecting The Instrument To The Lan

    The following port has to be enabled in the firewall on the internet gateway: — Port 443 (HTTPS) open for TCP In order to use the BUCHI Cloud a DNS server must be configured on the inter- face unit. NOTE If there is no DNS server available, the BUCHI Cloud connection must be configured by entering the IP address.

  • Page 78: Layout Of Buchi Monitor App

    R The BUCHI Monitor app is installed. Switch on the instrument. 8.9.1 Generating a QR code To connect the BUCHI Monitor app to the instrument, generate a QR code on the in- strument control panel. Navigation path ➔ Configuration ➔ Settings ➔ Mobile connection QR code Navigate to the action [Mobile connection QR code] via the navigation path.

  • Page 79: Scanning The Qr Code

    R The control panel shows the instrument's QR code. Start the BUCHI Monitor app on the mobile device. Tap the symbol [List]. The display shows a list of instruments that are connected to the BUCHI Monitor app. Tap the [(+)] sign in the top left corner.

  • Page 80: Connecting The Instrument And App Using A Password

    R The BUCHI Monitor app is installed. Switch on the instrument. 8.10.1 Generating a password To connect the BUCHI Monitor app to the instrument, generate a password on the in- strument control panel. Navigation path ➔ Configuration ➔ Settings ➔ Mobile connection password Navigate to the action [Mobile connection password] via the navigation path.

  • Page 81: Removing The Instrument From The App

    Removing the instrument from the app Start the BUCHI Monitor app on the mobile device. Tap the symbol [List]. The display shows a list of instruments that are connected to the BUCHI Monitor app. Tap the instrument that you wish to remove.

  • Page 82: Remotely Retrieving Process Data

    Tap [OK] to save the settings. 5 The display shows the [Settings] screen. 8.13 Remotely retrieving process data The data for the process currently running can be retrieved on the BUCHI Monitor app. Precondition: R The BUCHI Monitor app is connected to the instrument.

  • Page 83: Cleaning And Servicing

    Users may only carry out the servicing and cleaning operations described in this sec- tion. Any servicing and repair work which involves opening up the casing may only be car- ried out by BUCHI service technicians. Regular maintenance work Component...

  • Page 84: Performing A Vacuum Test

    9 | Cleaning and servicing BÜCHI Labortechnik AG Component Action Frequency View Wipe down the display with a damp Monthly cloth. Performing a vacuum test The vacuum test checks the performance capacity of the vacuum system. Time max. 10min quired: Navigation path ➜...
  • Page 85 BÜCHI Labortechnik AG Cleaning and servicing | 9 Time 45 min quired: NOTE The leak test can be aborted by tapping [Stop] on the function bar. Navigation path ➜ Configuration ➜ Servicing ➜ Leak test Precondition: R Conditioning of the instrument has been completed. R A top-mount drying rack is fitted.
  • Page 86 9 | Cleaning and servicing BÜCHI Labortechnik AG Possible cause Action 300 mm dia. O-rings dirty Wipe down the 300 mm O-rings with a damp cloth. 300 mm dia. O-rings damaged Inspect 300 mm O-rings and replace as necessary. KF clamps not closed Close the KF clamps. KF seals dirty Wipe down the KF seals with a damp cloth.

  • Page 87: Help With Faults

    BÜCHI Labortechnik AG Help with faults | 10 Help with faults 10.1 Troubleshooting Problem Possible cause Action Compressor fails to No power supply to compres- Check the power supply start or switches off and switch on the device. Compressor overheated Allow the compressor to cool down.

  • Page 88: Taking Out Of Service And Disposal

    Dispose of the appliance properly, if necessary using a professional disposal ser- vice. When disposing of equipment observe the local regulations and statutory require- ments regarding waste disposal. 11.2 Returning the instrument Before returning the instrument, contact the BÜCHI Labortechnik AG Service Depart- ment. https://www.buchi.com/contact 88/96 Operation Manual Lyovapor L-300...

  • Page 89: Appendix

    Appendix 12.1 Spare parts and accessories Use only genuine BUCHI consumables and spare parts in order to ensure correct, safe and reliable operation of the system. NOTE Any modifications of spare parts or assemblies are only allowed with the prior written permission of BUCHI.
  • Page 90 12 | Appendix BÜCHI Labortechnik AG Description Order no. Image Rack, for 6 shelves, complete 11065103 Non-heatable shelf, stainless steel 11065115 Heatable shelf, aluminum coated, with 11064095 connection cable Sample tray, stainless steal, D 220 mm 11061439 Ferrule, Ø 218 mm 11065816 Drying rack manifold, stainless steal, 11063664...

  • Page 91: Valve And Sensor Accessories

    BÜCHI Labortechnik AG Appendix | 12 Description Order no. Image Baseplate, stainless steel, for manifold 11064953 rack Baseplate, PMMA, for manifold rack 11065733 Manifold valve, comp, natural ruber, with 11062300 SJ 29/32 Suction nipple 11065819 12.1.2 Valve and sensor accessories Description Order no.

  • Page 92: Further Accessories

    12 | Appendix BÜCHI Labortechnik AG Description Order no. Image PT1000 sample temperature sensor 11064031 Level sensor capacitive, for water tank 11065245 12.1.3 Further accessories Description Order no. Image Canister 20l 11066068 Air filter 11057925 12.1.4 Spare parts Description Order no. Image User interface 11063580...
  • Page 93 BÜCHI Labortechnik AG Appendix | 12 Description Order no. Image Vacuum hose, KF 25, L 1000 mm 11066031 Vacuum clamp KF 16 11064939 Vacuum clamp KF 25 11063662 Vacuum clamp, stainless steal, KF 40 11063663 Sealing, FKM, KF 16, center ring 11063455 Sealing, FKM, KF 25, center ring 11063457...
  • Page 94 12 | Appendix BÜCHI Labortechnik AG Description Order no. Image Vacuum flange adapter, stainless steel, 11064870 KF 16 to KF 25 Blind flange, stainless steel, KF 16 11064902 Blind flange, stainless steal, KF 25 11063660 94/96 Operation Manual Lyovapor L-300...
  • Page 96 T +55 19 3849 1201 F +66 2 862 08 54 F +971 4 313 2861 F +55 19 3849 2907 bacc@buchi.com middleeast@buchi.com latinoamerica@buchi.com www.buchi.com/th-th www.buchi.com www.buchi.com/es-es We are represented by more than 100 distribution partners worldwide. Find your local representative at: www.buchi.com...

Table of Contents