Principle Of Operation - Agilent Technologies 1260 Infinity User Manual

1 Introduction

Principle of Operation

Principle of Operation
There are three steps in the operation of the detector:
1 nebulization of the eluent,
2 evaporation of the solvent and
3 detection of the compound(s) of interest
Figure 2
Nebulization involves the conversion of the eluent into a fine mist. The mist is
passed through an evaporator to vaporize solvent. In the detector unit, the
mist is irradiated by a light source and scattered light is measured by a
photomultiplier (PM). The degree of light scattering is related to the
concentration of the compound of interest in the sample. A cross sectional
view of the system is presented in
12
NEBULIZATION
Schematic Diagram of an Evaporative Light Scattering Detector
(Figure
EVAPORATION
Figure 3.
Agilent 1260 Infinity ELSD User Manual
2).
DETECTION