Epson IP-100 Setup And Direct Printing Manual page 21

5. Place the cartridges gently into their holders with the labels
face-up. The color ink cartridge, which is larger, goes on the
right and the black goes on the left. Do not press down on the
cartridges.
Note:
Install both ink cartridges. If either of the cartridges is not installed,
the printer will not work.
6. Press the ink cartridge clamps down until they lock in place.
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1-6
Setting Up Your Printer
Caution:
Once you install the ink cartridges, do not open their clamps
again until you replace the ink cartridges. Otherwise, the
cartridges may become unusable.