Gateway E-4620 Reference Manual page 50

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CHAPTER 4: Upgrading Your Computer
If you are removing a 5.25-inch component, pull down
on the 5.25-inch bay's release latch to the Unlock
position, then slide the component forward and out of
the bay.
If you are only replacing a 5.25-inch component, note
any jumper settings on the old drive and set the jumper
on the new drive to be the same, then go to Step 12.
- OR -
If you are replacing a 3.5-inch component, lift the
5.25-inch component bay out of the chassis.
Push up on the release latch on the 3.5-inch component
bay to move it to the Unlock position, then slide the
component forward and out of the bay.
Note any jumper settings on the old drive and set the
jumper on the new drive to be the same.