Epson ActionTower 3000 Computer User Manual page 84

2. Remove the four screws (two on each side) securing the drive
to the drive bay. Then slide the drive out through the front
of the bay.
3. If you are not installing an externally accessible drive in the
open drive bay, you need to install a drive slot cover for
that bay. Push the slot cover into the open bay until the tabs
on the cover click into place.
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Installing and Removing Drives