If electronic or other form without prior written consent of Epredia. this symbol appears on the instrument, All information contained in this manual is proprietary and always refer to the operator guide.
Chapter 1 – Introduction Chapter 2 – Operating Instructions Initial turn-On ..........11 Installing the Cool-Cut on the Rotary Microtomes HM 310, HM 315, HM 325 and HM 340 E ..11 Installing the Cool-Cut on the Rotary Microtome HM 335 E ............. 12 Installing the Cool-Cut on the Rotary Microtomes HM 355, HM 355 S and HM 360 ....
Safety Information Introduction Related to the potential hazards of the specimens to be processed personal Epredia instruments are designed for convenient and protection measures shall be considered: reliable service; however, improper use or handling • protection gloves by a user may damage the instrument or cause a hazard to health.
Warranty Statement chemicals in the instrument, do so at their own risk. Epredia are proud of their quality, reliability and of our after-sales service. We continuously strive to improve • All chemicals recommended by Epredia our service to our customers.
Chapter 1 – Introduction IVDR Intended Purpose The Epredia Cool-Cut is an in vitro diagnostic device intended to be used alongside the rotary microtomes. It is designed to cool samples for taking precision sections of tissue specimens including the sectioning of paraffin embedded...
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Power requirements: 100-240 V / 0.6 A +/-10%/50...60 Hz 7.5V DC/3.3A Pollution degree: Protection Class Power Supply Class II Device Cool-Cut Class III Overvoltage category: Acoustic pressure: 20 dB(A) Dimensions: 180 x 60 x 95 mm (long x wide x deep)
Initial turn-On placed on the hand wheel (fig. 4.6) by using a small screwdriver. The Cool-Cut can be adapted to all current rotary • Remove the hand wheel handle (fig. 4.5) using microtomes from Epredia. the attached Allen key (size 5).
Otherwise, there is the conventional specimen clamps". danger to get injured. • Now fit the Cool-Cut to the orienting adapter The Cool-Cut is heavier than a on the microtome using the clamping lever on specimen clamp without cooling the microtome.
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(fig 2.6) into the socket of the Cool-Cuts (fig. 2.7). Fig 5 • The specimen clamp of the Cool-Cut is now being cooled down. Now insert the hand wheel handle together with the respective distance ring (fig. 5.2) into the •...
• If the specimen clamp is still installed, remove • Now fit the Cool-Cut to the orienting adapter it. For this, loosen the clamping lever and on the microtome using the clamping lever on remove the clamp from the microtome.
• If the specimen clamp is still installed, remove 2.7). it. For this, loosen the clamping lever and • The specimen clamp of the Cool-Cut is now remove the clamp from the microtome. being cooled down. • Now fit the Cool-Cut to the orienting adapter •...
Fig 7 Sectioning of Specimens Especially at high ambient temperatures, the lower specimen temperature generated by the Cool-Cut has very positive effects on the sectioning results. The active cooling of a paraffin specimen clamped in the specimen clamp allows thin sections of excellent quality without re-cooling the specimen.
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Changing to Conventional Specimen Clamps As an average, the Cool-Cut is 400 g heavier than a conventional specimen clamp. The counterweight increases the weight on the hand wheel accordingly. Resulting in a smooth run of the rotary microtome during the sectioning process with the Cool-Cut.
Standard Equipment The Cool-Cut is supplied with the following accessories: Cool-Cut complete with standard specimen Cool-Cut complete with universal cassette clamp clamp (cat. no. 771120) (cat. no. 771110) • 2 screws • 2 screws • 1 distance ring • 1 distance ring •...
Peltier element. The cooling plate on the rear side of the specimen clamp warms up during operation with the Cool-Cut. In its upper area, a fan is place for eliminating the heat Cool-Cut Operator Guide Issue 18...
Cool-Cut, or the socket or the cable might be damaged. How to Proceed in Error Cases Note In case of an error, the Cool-Cut must only be checked or repaired by trained skilled service personnel. Note In case components or assemblies must be replaced, only original spare parts must be used.
Do not use Acetone! The user must care for a clean and safe condition of the instrument To clean the specimen clamp of the Cool-Cut when returning it to an appropriate from paraffin, use a cloth soaked with solvent. service provider.
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• Industrial users should contact their suppliers and observe the conditions of the contract. This product must not be disposed of together with other commercial waste. • Please contact your supplier!! Cool-Cut Operator Guide Issue 18...
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Installing the Cool-Cut on the Rotary Microtomes HM 355, HM 355 S and HM 360 ....14 How to avoid malfunctions ......20 Orienting the Cool-Cut on a Rotary Microtome ..17 How to Proceed in Error Cases ....... 20...
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Revision Control for this Document Date Revision number Changes made February 2022 IVDR compliance requirements added, including this revision record table.
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