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Agilent NanoDis
Quick Start Guide
This guide covers the following modules: Agilent NanoDis System (G7937AA)
Additional Equipment Required (Not Supplied)
Agilent Technologies does not supply Cross Flow Filters. For further information and recommended suppliers,
contact the Dissolution team (dissolution.hotline@agilent.com).
Damage of equipment by overpressure
C AU T I O N
A closed top horizontal filter connection during experimentation can cause potentially
damaging pressure build-up in the filter and the system.
Leave open the top horizontal connection of the filter during experimentation.
Installation of Peristaltic Pump Tubing and Cassettes
To install the peristaltic pump tubing and cassettes, complete the following steps:
Remove the cassettes by pressing the barbed part of the cassette and pushing it upwards.
1
Using the peristaltic pump tubing, attach the tubing adapters and fasten them into the cassettes. Ensure that the
2
tubing clips are embedded correctly, see
3
Ensure that the pressure control lever is fully open. Re-insert the cassette into the Peristaltic Pump and secure
them by re-attaching the side support bar, see
Adjust the pressure control lever so that sufficient pressure is applied to the peristaltic pump tubing to allow free
4
flow of the media. A flow rate of 40 corresponds to an approx. flow rate of 6.0 mL/min
Figure 1
Peristaltic Pump Cassette
NanoDis Quick Start Guide
Figure 1
on page 1.
Figure 2
on page 1.
Figure 2
Installing Cassettes

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Summary of Contents for Agilent Technologies NanoDis

  • Page 1 Quick Start Guide This guide covers the following modules: Agilent NanoDis System (G7937AA) Additional Equipment Required (Not Supplied) Agilent Technologies does not supply Cross Flow Filters. For further information and recommended suppliers, contact the Dissolution team (dissolution.hotline@agilent.com). Damage of equipment by overpressure...
  • Page 2 NanoDis Quick Start Guide NanoDis System Tubing Guide The following Figure 3 on page 2 shows the components of the NanoDis System and provides information about the required tubings. Agilent 708-DS Agilent 850-DS Hollow-Fiber Dissolution Apparatus Dissolution Sampling Station Filters...
  • Page 3 NanoDis Quick Start Guide Example 1: = 4.0 mL (programmed in system) PrimeLoss = 3.0 mL Filter = 3.5 mL PrimeTubing = 3.0 mL — (4.0 mL — 3.5 mL) SampleMax = 2.5 mL SampleMax Calculation of Filter Outer Volume...
  • Page 4 Replace the vessel media and rinse media for this method. Technical Support and Further Information For technical support, contact dissolution.hotline@agilent.com. Visit the Agilent Technologies website for useful information, support, and current developments about the products and technology: https://www.agilent.com/en/product/dissolution-testing/dissolution-apparatus/nanodis-system www.agilent.com ...