Edimax BR-6424n User Manual page 117

When you finished with the settings in this page, you can click 'Apply'
button to save changes you made in this page, or you can click 'Cancel'
to discard changes. After you click 'Apply' button, you'll see the
following messages:
Please click 'Apply' to save changes you made and restart the broadband
router, this requires about 30 seconds and the broadband router will stop
responding (this is normal and is not malfunction). You can reconnect to
this broadband router and continue on other settings later.