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THE INSTRUMENT IN SAFE CONDITIONS. SERVICE AND ADJUSTMENTS SHOULD BE CARRIED OUT BY QUALIFIED PERSON- NEL, AUTHORIZED BY UGO BASILE ORGANIZATION. ANY ADJUSTMENT, MAINTENANCE AND REPAIR OF THE OPENED INSTRUMENT UN- DER VOLTAGE SHOULD BE AVOIDED AS MUCH AS POSSIBLE AND, WHEN INEVITA- BLE, SHOULD BE CARRIED OUT BY A SKILLED PERSON WHO IS AWARE OF THE HAZARD INVOLVED.
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Cat. No. 58500 for Rats Cat. No. 58600 for Mice Cat. No. 58550 for Rats & Mice General The BP RECORDER 58500 combines three main systems pressure generation-pressure monitoring system a pulse amplifier and a thermal-array analog & digital recording unit...
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CHECK-LIST UGO BASILE S.R.L. CAT: 58500 BP Recorder for Rat BIOLOGICAL RESEARCH CAT: 58600 BP Recorder for Mouse APPARATUS CAT: 58700 BP Recorder for Dog CLIENTE / CUSTOMER______________________________________________ No. Ordine / Order No. ____________________ Data / Date____/_____/______ √ UB code CAT.No.
UGO BASILE - I Page i TALY 47105 Instruction Manual (Rev. 2) C O N T E N T S INTRODUCTION INSTRUMENT DESCRIPTION RESSURE ENERATOR YSTEM OMMAND VERVIEW HART ECORDER UFFS ULSE RANSDUCERS NIMAL ESTRAINERS PTIONAL NIMAL EATER CANNER DATA ACQUISITION INSTALLATION &...
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UGO BASILE - I Page ii TALY 47105 Instruction Manual (Rev. 2) UTOMATIC EASUREMENT ANUAL EASUREMENT TARTING THE RESSURE EASUREMENT CALIBRATION DATA PRINT-OUT AND OUTPUT TO THE PC OW TO ET THE UTPUT NSTRUMENT DDRESS AND OW TO ET A...
(stepless) pres- sure build-up iii) an analog and digital recording of all the phases of the experiment The 58500 combines together three main systems:- pressure generation-pressure monitoring system pulse amplifier thermal-array analog & digital recording unit...
UGO BASILE - I Page 2 TALY Series 58000 Instruction Manual (Rev.1) INSTRUMENT DESCRIPTION Figure 1 “Pressure Generator” Pressure Generator System A geared motor (1), via a crank-link-gudgeon (2, 3, 4) causes the forward and reverse motion of a piston (5) into a stationary cylinder (6), see Figure 1 “Pressure Generator”.
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UGO BASILE - I Page 3 TALY Series 58000 Instruction Manual (Rev.1) The piston motion reverses and the decompression phase begins. The systolic pressure is indicated, this time, by the return of the pulse trace. The pulse rate of the animal is automatically assessed in real time by a pulse rate counter which picks the signal from the pulse transducer.
UGO BASILE - I Page 4 TALY Series 58000 Instruction Manual (Rev.1) Figure 3 “Sample of a Graph” Note the port (14) on the side of the cylinder which enables the pressure run to start at room pressure. The blow-out valve allows the operator to depressurize the system and to interrupt and abort the trial at any time, whereupon the trial is brought to an end.
UGO BASILE - I Page 5 TALY Series 58000 Instruction Manual (Rev.1) In fact, the recorder status and functions are set-up automatically and visualized via the display. The dedicated keys (DECOMPRESSION, which releases the pneumatic system and causes the piston to speed back to its starting point, when depressurization is neces- sary, see paragraph 2.4-Tail Cuffs).
UGO BASILE - I Page 6 TALY Series 58000 Instruction Manual (Rev.1) Tail Cuffs The rat and mouse tail cuffs, available in different diameters (see 13.2-Available Tail Cuffs) are of simple and straightfor- O-RING ward design: they combine a sturdy short...
UGO BASILE - I Page 7 TALY Series 58000 Instruction Manual (Rev.1) Animal Restrainers Convenient animal restrainers are provided with the standard package. Our models are particularly suitable, see Figure 7 “Rat Holder”, being purposefully designed for this task, as they feature:- a conical “muzzle”...
9-pin D-type connector to the PC serial port (RS232) see para- graph 9-DATA PRINT-OUT AND OUTPUT TO THE PC. Serial communication between 58500 BP Recorder and an IBM (or compatible) PC is controlled by Ugo Basile Win-DAS Software Cat. 52010 supplied as optional. See 13.5-Optional.
UGO BASILE - I Page 9 TALY Series 58000 Instruction Manual (Rev.1) Dispose of packaging properly, according to existing and ap- plicable waste management rules and regulations. Notes on the Instruction Manual The BP Recorder Instruction Manual included in accessory package is necessary for the correct installation and operation of the instrument.
UGO BASILE - I Page 10 TALY Series 58000 Instruction Manual (Rev.1) 4.3.2 Fuse Holder & Voltage Selector The fuse holder comprises two fuses, one on the live, and the other on the neutral. For operation at 230-240 Volts, we recommend 315 mA timed “slow blow” fuses (type T315). Use 630 mA fuses (type T630) for operation at 115 Volts.
(i.e. 10°C / +40°C, 95% relative humidity, non-condensing). Do not spray any liquid on the connectors. UGO BASILE DOES NOT ACCEPT ANY RESPONSIBILITY FOR PROB- LEMS OR HARM CAUSED TO THINGS OR PERSONS ARISING FROM: ♦ INCORRECT ELECTRICAL SUPPLY.
UGO BASILE - I Page 12 TALY Series 58000 Instruction Manual (Rev.1) As alternative, it is suggested to prewarm at lower temperature, say, 26-27°C which, after all, is not worse than a hot Summer day, and then apply local heating.
UGO BASILE - I Page 13 TALY Series 58000 Instruction Manual (Rev.1) Switching On Switch on the instrument. Momentarily, the display will read “V01” (firmware version 01) according to the following pic- ture: The top line (now 000) indicates the actual pressure in the tail cuff.
UGO BASILE - I Page 14 TALY Series 58000 Instruction Manual (Rev.1) WARNING: it is advisable to insert a small cylinder (a fountain pen has the appropriate diame- ter) into the cuff, to prevent a possible burst of of the membrane when the pressure builds up during dry-run test..
UGO BASILE - I Page 15 TALY Series 58000 Instruction Manual (Rev.1) UP/DOWN the pressure measurements are taken during the compression phase (UP) and the decom- pression (DOWN) phase; DIA/SYS the instrument is set to record both diastolic & diastolic pressure;...
UGO BASILE - I Page 16 TALY Series 58000 Instruction Manual (Rev.1) In fact, the respiration, the struggling and any other possible noise are linked to the size of the animal. As a rule of thumb, larger the animal, lower the frequency of the artifacts.
UGO BASILE - I Page 17 TALY Series 58000 Instruction Manual (Rev.1) At this point, select among automatic (F1 AUT) or manual (F2 MAN) measurement. Automatic Measurement The instrument takes about three seconds to check the pulse amplitude, see the picture on the right.
UGO BASILE - I Page 18 TALY Series 58000 Instruction Manual (Rev.1) Act on the arrows keys F1 ( ↑ ) or F2 ( ↓ ) to ob- tain a signal within the display limits. To obtain an optimal reading,...
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UGO BASILE - I Page 19 TALY Series 58000 Instruction Manual (Rev.1) When the pressure has descended to 50 mm Hg, the chart motion stops whilst the piston contin- ues its run until its travel end. At this point the cylinder comes in connection with the room air via a side port.
M1 which means animal No. 1, male, F3 which means animal No. 3, female, etc. CALIBRATION To calibrate means to compare the pressure reading of 58500 with the data supplied by a precision mercury pressure gauge (or any other certified pressure standard) capable to...
UGO BASILE - I Page 21 TALY Series 58000 Instruction Manual (Rev.1) It is advisable to calibrate the instrument at monthly intervals, in particular when it works daily. Connect the pneumatic outlet (the outlet to which you connect the cuff) to the standard pressure gauge.
UGO BASILE - I Page 22 TALY Series 58000 Instruction Manual (Rev.1) To print the graph and the digital data on the Chart Recorder, from the main menu press F2 (FNC) key, followed by the F1 (OUT) key. Press the F1 (PAT) key again; a display like the one shown here will appear.
UGO BASILE - I Page 23 TALY Series 58000 Instruction Manual (Rev.1) How to Set a Customized Experimental Configuration From the main menu, press the F2 (FNC) key, followed by the F1 (OUT) key. Depress the key F2 (FTR) again; the display shows:-...
UGO BASILE - I Page 24 TALY Series 58000 Instruction Manual (Rev.1) IMPORTANT: When a fresh experimental session begins, the sequence number can commence from the last number reached at the end of the previous trial, otherwise, a fresh number can be entered, following the instructions outlined above, for example starting from 01.
UGO BASILE - I Page 26 TALY Series 58000 Instruction Manual (Rev.1) Before selecting the output, the operator will be asked if he/she is interested to tag each datum with the related Date & time, by answering (YES) (F3 key) or (NO ) (F4) to the ques- tion “WITH DATE &...
UGO BASILE - I Page 27 TALY Series 58000 Instruction Manual (Rev.1) The operator is now required to answer (YES) (F3 key) or (NO) (F4 key) to the question: “are you sure?”. This confirmation has been added to avoid the accidental loss of all stored data.
Leave this software level, saving the selected display contrast, by pressing the F4 (ESC) key. MAINTENANCE While any service of the instrument is to be carried out by Ugo Basile personnel or by qualified personnel, authorized by UGO BASILE organization, this section of the instruction manuals de- scribes normal maintenance procedures which can be carried out at the customer’s facilities.
UGO BASILE - I Page 29 TALY Series 58000 Instruction Manual (Rev.1) 12.1 Electrical To inspect and/or replace the fuses, disconnect the mains cable first! Insert a minia- ture screwdriver in the slot indentation, see paragraph 4.3-Fuse Holder & Voltage Selec- tor, and snap out the slide which houses the fuses.
UGO BASILE - I Page 30 TALY Series 58000 Instruction Manual (Rev.1) Figure 11 “Paper Roll” 12.4 Long Inactivity The instrument does not require any particular maintenance after long inactivity, except cleaning. Check the consistency of rubber membranes and O-rings and replace them, if necessary. Re- member that both should be stored away from daylight which in the long run degrades their con- sistency.
UGO BASILE - I Page 31 TALY Series 58000 Instruction Manual (Rev.1) Before sending any instrument to our factory for repair, we recommend you to get in touch with our service department (mentioning the serial number of your instrument) to obtain a return authorization number (R.A.N.) and shipping instructions.
UGO BASILE - I Page 32 TALY Series 58000 Instruction Manual (Rev.1) 13.2 Available Tail Cuffs 58000-606 Tail Cuff for Mouse, diam. 6 mm 58000-609 Tail Cuff for Rat, diam. 9 mm 58000-613 Tail Cuff for Rat, diam. 13 mm 58000-620 Tail Cuff for Dog, diam.
UGO BASILE - I Page 33 TALY Series 58000 Instruction Manual (Rev.1) 58000-845 Rat Heater, complete with 5 rat holders of selectable I.D. 58000-850 Rat Scanner, complete with 5 rat holders of selectable I.D. NOTE Pressure cuffs & pulse pick-ups are not included and are to be purchased separately 13.6...
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UGO BASILE - I Wiring Diagram TALY Series 58000 Instruction Manual (Rev.1) WIRING DIAGRAMS 58000-001ES01 (sh 1 of 4) Wiring Diagram 58000-001ES01 (sh 2 of 4) Wiring Diagram 58000-001ES01 (sh 3 of 4) Wiring Diagram 58000-001ES01 (sh 4 of 4)
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We hereby declare that Instrument. BLOOD PRESSURE RECORDER RAT/MOUSE Catalog number 58500 – 58600 - 58550 is manufactured in compliance with the following European Union Directives and relevant harmonized standards 2006/42/CE on machinery 2014/35/UE relating to electrical equipment designed for use within certain voltage limits ...
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