Page 2
INSTRUCTION MANUAL 16-CHANNEL EXTRACELLULAR AMPLIFIER MODEL 3500 Each 16-Channel Extracellular Amplifier is delivered complete with: Sixteen 40” Input Cables 10’ USB Cable Rack Mount Hardware Version 6.0 March 2020 A-M Systems, PO Box 850 Carlsborg, WA 98324 U.S.A. 360-683-8300 800-426-1306 FAX: 360-683-3525 http://www.a-msystems.com...
Page 3
The Warning symbol calls attention and should not be construed as a type. to a procedure or practice, which, if commitment by A-M Systems. not correctly performed could Changes may have been made to Supply Voltage result in injury. Do not proceed...
1. General Description The Model 3500 contains 16 low noise, high gain full-featured extracellular amplifiers, or channels, designed for amplifying microvolt-level input signals. All parameters can be controlled via the unit’s touch screen LCD display on the front panel or via a USB link to a personal computer running a supplied Windows ®...
Chapters 3 and 4 describe the individual screens available on the touch-screen LCD interface. When you receive your Model 3500, confirm that everything in the packing list is included. Make sure there are no obvious signs of internal damage, such as rattling. Pick up the amplifier and tilt in gently from side to side, and listen for anything that might be loose.
Channel Signal Input This black 3-pin connector is the signal input connector for the Model 3500. Pin 1 (upper left) is the “-” lead, pin 2 (bottom left) is the “+” lead, and pin 3 (middle right) is the grounded shield (This can be a non-grounded driven shield if desired.
Page 8
Windows operating system compatible control program to ® control the Model 3500 by attaching it to an available USB port on the computer using the USB cable supplied with the instrument. Common Reference Connector Input to this BNC can serve as a common reference for any or all Figure 9.
Page 9
The Model 3500 should be delivered with the appropriate mains power voltage set, at either 100-120 volts or 220-240 volts. A red slide switch located on the back panel just above the power input determines this setting.
The touch-screen LCD should illuminate and the A-M Systems logo should be displayed briefly as the on-board software loads. After the initial software loads, the Calibrate Screen Process will begin. By touching the indicated targets, the software responsible for tracking user input will determine the user’s local pressure...
Page 11
ON implements the filter. OFF removes the filter. The NOTCH filter can be tuned for the AC line frequency in the country where the Model 3500 is being used by accessing the NOTCH FILTER PAGE via the MAIN MENU (See Chapter 4).
At this point, the unit is defined and functional on all channels. Further details on all instrument functions are described in the next chapter. A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525...
Additional details on each of these screen options follow. Figure 14. Main Menu Screen A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525 E-mail: sales@a-msystems.com * Website: http://www.a-msystems.com...
Load Screen LOAD screen displays a list of five memory locations that are stored within the Model 3500 and are saved even after AC power to the unit is shut off. These memory locations store the critical parameters of all 16-channels in a single file. A memory location is selected by highlighting the parameter set name (or program) name.
MAIN MENU, without writing the current parameter values in any memory location. SHIFT will toggle the screen from capital letters to lower case letters. Figure 16. Save Screen A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525 E-mail: sales@a-msystems.com * Website: http://www.a-msystems.com...
CANCEL terminates the process and makes no change to the current startup program selection. Figure 17. Set Startup Screen A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525 E-mail: sales@a-msystems.com * Website: http://www.a-msystems.com...
MAIN MENU. CANCEL does not store the new name, and the unit returns to the MAIN MENU. Figure 18. Instrument Name Screen A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525 E-mail: sales@a-msystems.com * Website: http://www.a-msystems.com...
DONE returns the unit to the last displayed channel screen (CHANNEL EDIT, 8-CHANNEL, or 16-CHANNEL VIEW). Figure 19. Reference Screen A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525 E-mail: sales@a-msystems.com * Website: http://www.a-msystems.com...
DONE returns the unit to the last displayed channel screen (CHANNEL EDIT, 8-CHANNEL VIEW, or 16-CHANNEL VIEW). Figure 20. Notch Filter Screen A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525 E-mail: sales@a-msystems.com * Website: http://www.a-msystems.com...
Figure 21. Stimulation Input Screen The Model 3500 has two separate stimulation signal buses (STIMULATION INPUT BNC 1 and STIMULATION INPUT BNC 2) that correspond to two groups of channels. Channels 1 through 8 can be connected to STIMULATION INPUT BNC 1. Channels 9 through 16 can be connected to STIMULATION INPUT BNC 2.
The REVERSE LCD button will reverse the color of the screen from dark letters on a light background, to light letters on a back background, and back again. Figure 22. Contrast Screen A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525 E-mail: sales@a-msystems.com * Website: http://www.a-msystems.com...
Version Screen The VERSION screen displays the latest version numbers of the software and hardware the Model 3500 currently uses. This diagnostic tool should be used before contacting A-M Systems for service. A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525 E-mail: sales@a-msystems.com * Website: http://www.a-msystems.com...
If more settings are available then can be displayed in a list, an up or down arrow might be displayed which will shift the list accordingly if pressed. A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525...
SELECT LIST , and the values of channel 4 will be highlighted in the parameter list. 8-Channel View Screen Pressing 8 at the top of any screen will display the 8-CHANNEL VIEW screen. A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525...
Pass Filter, and Gain settings) of all 16 channels. Pressing the arrow in the lower right-hand corner will switch the display to the other parameters (Notch, Common Reference, and Mode). A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525...
MULTICHANNEL SELECT LIST. Output Monitors and Calibration Signal Screen For user convenience, the Model 3500 has Figure 30. 16-Channel View Screen Two two channel output monitors (BNC connectors A and B) available on the front panel.
Page 29
Figure 31. Monitor and Calibration Signal Screen A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525 E-mail: sales@a-msystems.com * Website: http://www.a-msystems.com...
5. PC Control Software The Model 3500 can be controlled by Windows compatible software that is available for download at www.a-msystems.com. The downloadable control software runs on Windows 10, 7, and, ® Windows XP. The section that follows covers installation procedures for Windows 10. If you ®...
Page 31
Extract the files to a new folder: The Model 3500 control software requires the Microsoft® .NET Framework version 1.1 or later to function. Once extracted, double click to run the “dotnetfx.exe” file. A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525 E-mail: sales@a-msystems.com * Website: http://www.a-msystems.com...
Page 32
An additional dialog box to begin .NET installation. Select “I agree” to proceed. After .Net is installed, a dialog box will appear. Click “OK” to close. A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525...
Page 33
Return to the installation software folder and double click on “Setup.exe” to install the Model 3500 Control Software. The Model 3500 control software installation wizard will ask for permission to install: A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525 E-mail: sales@a-msystems.com * Website: http://www.a-msystems.com...
Page 34
A dialog box suggesting the file location will open. A question asks for who should be able to use the pc control software. Select “Everyone” and click “Next” A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525...
Page 35
Confirm that you want to install the software by clicking “Next.” Once installation is complete, a final dialog box will be displayed: Press “Close” to exit. A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525...
Using the Control Software After the program has been installed, you can run it from the Start Menu by selecting Programs -> A-M Systems -> Amplifier Control Panel Figure 32. PC Software If your program loaded successfully, after a brief display of our company logo, the program window shown in Figure 32 should appear.
Page 37
If the Model 3500 is turned on and attached to the computer when the control software is executed, then the instrument name and serial number should appear in the list located in the upper left corner of the main window under the heading INSTRUMENTS/FILES. If it is not listed, or if it is connected to the computer after the control software is started, select Refresh from the Instruments menu (or press F5) to refresh the list of available instruments.
Page 38
STIM 2 BNC connector, or the rear panel STIM 1 BNC connector. When the Model 3500 is under TTL control, the MODE settings in the control software will be ignored and the instrument will respond according to the TTL signal provided. All of the other settings will remain under the control of the computer software.
6. External TTL Control The provided EXTERNAL TTL CONTROL on the Model 3500 rear panel enables the user to control the mode of any channel remotely. In order for the unit to respond to TTL inputs, pin 19, the unit’s TTL ENABLE LINE, needs to be brought high by applying a voltage greater than 3 volts.
Page 40
Blank Enable Channel 1 Stimulation Enable Channel 1 Master Blank Enable Ground Link Stimulation Buses Vcc (5V) TTL Control Enable A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525 E-mail: sales@a-msystems.com * Website: http://www.a-msystems.com...
Page 41
TTL inputs. A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525...
50Hz or 60Hz (User Selected) Rejection: >30dB Calibration Signal Frequency 1kHz sine wave, Amplitude 1, 10, 100 or 1000mVp-p A-M Systems PO BOX 850, Carlsborg, WA 98324 USA Telephone: 800-426-1306 * 360-683-8300 * FAX: 360-683-3525 E-mail: sales@a-msystems.com * Website: http://www.a-msystems.com...
What are the obligations of A-M Systems under this warranty? During the warranty period, A-M Systems agrees to repair or replace, at its sole option, without charge to the Purchaser, any defective component part of the hardware. To obtain warranty service, the Purchaser must return the hardware to A-M Systems or an authorized A-M Systems distributor in an adequate shipping container.
Page 44
What are the limits of liability for A-M Systems under this warranty? A-M Systems shall not be liable for loss of data, lost profits or savings, or any special, incidental, consequential, indirect or other similar damages, whether arising from breach of contract, negligence, or other legal action, even if the company or its agent has been advised of the possibility of such damages, or for any claim brought against you by another party.
Page 45
A-M Systems, 3500 Manual DRW-5027905 Rev 6 Approved: Revision History Date Description 6/30/06 Initial Document Release 11/2/06 Swapped pins 14 and 16 on the ganged output pin description. 4/28/10 DCR 201200 Warranty information and company info 1/18/17 DCR 201985, 201996, 202287. Update computer installation.