User Manuals: Astrea Evolve Bioseparation Columns

Manuals and User Guides for Astrea Evolve Bioseparation Columns. We have 2 Astrea Evolve Bioseparation Columns manuals available for free PDF download: Technical User Manual, User Manual

Astrea Evolve Technical User Manual (40 pages)

Process Columns (200 & 250mm diameter columns)

Brand: Astrea | Category: Industrial Equipment | Size: 1 MB

Table of Contents
3
Table of Figures
5
Column Hardware
6
Mechanical Description
6
Design Features
6
Technical Data
7
Weights and Dimensions
7
Pressure Drop
8
Figure 1 Pressure Drop Evolve™ 200 MM Process Column
8
Figure 2 Pressure Drop Evolve™ 250 MM Process Column
8
Material Conformity
9
Materials of Construction - Process-Wetted Parts
9
Materials of Construction - Non Process-Wetted Parts
9
Chemical Compatibility
10
Safety Guidelines
12
Safety Considerations
12
Pressure Equipment Directive (PED)
12
Over-Pressurization
12
Handling
12
Chemical Compatibility
12
Column Installation and Operation
13
Column Installation
13
Installation of Bed Supports
13
Installation of Fixed Bed Support
13
Figure 3 Diagram Showing the Location of the Fixed Bed Support
13
Installation of Height Adjustable Feet
14
Levelling the Evolve™ Process Columns
14
Figure 4 Photograph Showing the Installation of the Fixed Bed Support
14
Installation of Adjuster Bed Support
15
Figure 5 Height Adjustable Feet
15
Figure 6 Diagram Showing the Location of the Adjuster Bed Support
15
Setting the Bed Height
16
Figure 7 Photograph Showing the Location of the Adjuster Bed Support
16
Column Operation
17
Hydrostatic Leak Test
17
Column Packing (Constant Flow Rate Method)
18
Figure 8 Schematic of the Column with Part Identification
20
Unpacking
21
Cleaning
21
Storage
21
Maintenance
22
Routine Maintenance Procedures and General Guidelines
22
Disassembly of Evolve™ Process Columns
23
Adjuster Assembly
23
Figure 9 Adjuster Assembly for Evolve
23
Fixed Assembly
24
Figure 10 Fixed Assembly for Evolve
24
Figure 11 Position of the Support Blocks before the Fixing Bolts
24
Tube Assembly
25
Reassembly of Evolve™ Process Columns
25
Fixed Assembly
25
Figure 12 Diagram Showing the Location of the Fixed Bed Support
25
Figure 13 Photograph Showing the Installation of the Fixed Bed Support
25
Adjuster Assembly
26
Figure 14 Position of Fixed End Support Blocks to Enable Relocation
26
Figure 15 Diagram Showing the Location of the Adjuster Bed Support
26
Figure 16 Photograph Showing the Final Location of the Adjuster Bed Support
27
Figure 17 Photograph Showing the Alignment of Markings on Flow Tube and
27
Troubleshooting
29
Leakage from Adjuster Seal
29
Leakage from Fixed Bed Support Seal
29
Leakage from Inlet or Outlet
29
Excessive Column Back Pressure
29
Media Leakage
30
Ready to Use
31
Kits Supplied with Column
31
Tool Kit
31
Connection Kit
31
Spares Kit
32
Spare Parts, Kits & Accessories
33
Column Refresh Kit
33
Wetted Flow Path Kit
34
Bed Support Kit
34
Elastomer Seal Kit
35
Adjuster Cell Kit
35
Torque Wrench Kit
36
Fixed Cell Kit
36
Fluid Connection Kit (200 & 250 MM Diameter Columns)
36
Flexible Hose (200 & 250 MM Diameter Columns)
36
Adjustable Foot Kit
37
Chromatography Performance
38
Figure 18 Description of Column Efficiency Calculations
38

Astrea Evolve User Manual (19 pages)

350mm Column Instructions for Replacing the Wetted Flowpath using the Column Refresh Kit

Brand: Astrea | Category: Industrial Equipment | Size: 1 MB

Table of Contents
2
Replacing the Wetted Flowpath
3
General Guidelines
4
STAGE 1 - Refresh the Adjuster Assembly
6
Step 1-Disassembly of Adjuster Assembly
6
Step 2-Reassembly and Refresh the Adjuster Assembly
8
STAGE 2 - Refresh the Tube Unit Assembly
10
Step 1-Disassembly of the Tube Unit
10
Step 2-Reassembly and Refresh the Tube Unit
12
STAGE 3 - Refresh the Fixed End Assembly
13
Step 1-Disassembly of the Fixed End Assembly
13
Step 2-Reassembly and Refresh of the Fixed Assembly
14
STAGE 4 - Column Reassembly and Preparation for Use
15
Step 1 - Assemble Tube Unit Onto the Column Base and Bottom Flowcell
16
Preparing for Column Use
18
Step 1 - Hydrostatic Leak Test
18
Step 2 - Levelling the 350Mm Columns
18

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User Manuals: Astrea Evolve Bioseparation Columns

Astrea Evolve Technical User Manual (40 pages)

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