Table of Contents
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You have just purchased one of the finest Laminar Flow Biosafety Cabinets available. With proper care, maintenance
(certification), and laboratory procedure, this cabinet will give you years of product and personnel protection from particulate
Labgard ES Energy Saver Class II,
Type B1 Laminar Flow
Biosafety Cabinet
Models
NU-427-400/600
Bench/Console
Operation & Maintenance Manual
NU-427-400/600 Series BR
Revision 2 September 2020
Manufactured By:
Nuaire, Inc.
2100 Fernbrook Lane
Plymouth, MN 55447
Toll-Free: 1-800-328-3352
In Minnesota: (763)-553-1270
Fax: (763)-553-0459
Page 1 of 100
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Table of Contents
Related Manuals for NuAire Labgard NU-427-600
Summarization of Contents
General Information
Biosafety Cabinet Description
Provides a detailed overview of the Labgard ES Model NU-427 Laminar Flow Biosafety Cabinet.
Installation and Setup
Cabinet Location Guidelines
Recommendations for selecting an optimal and safe location for the biosafety cabinet installation.
Cabinet Set-Up Procedures
Step-by-step instructions for setting up the biosafety cabinet, including base stand and leveling.
Base Stand Assembly Instructions
Guidance on assembling the base stand for the biosafety cabinet according to provided drawings.
Leveling Procedure
Instructions on how to properly level the biosafety cabinet using its adjustable leg levelers.
Operating the NU-427 Biosafety Cabinet
Biosafety Cabinet Control System
Explanation of the Biosafety Cabinet Control (BSCC) system and its functions.
Control System Overview
Introduction to the BSCC system's features, user interface, and basic operations.
Standby Mode Operation
How the biosafety cabinet operates and displays information when in standby mode.
Run Mode Operation
Procedures and display information for operating the biosafety cabinet in run mode.
Calibration and Service
Calibration/Service Menu Navigation
How to access and navigate the Calibration/Service menu for system adjustments.
Cabinet and Motor Type Configuration
Setting the cabinet type and motor type within the control system for accurate operation.
Airflow Calibration Procedure
Step-by-step process for calibrating the downflow and inflow airflow measurements.
Downflow Airflow Calibration Process
Detailed steps for calibrating the downflow airflow sensor and blower duty cycle.
HEPA Filter Integrity and Airflow Testing
HEPA Filter Leak Test Procedures
Methods for testing the integrity and seal of HEPA filters.
Airflow Smoke Pattern Testing
Using smoke to visualize airflow patterns within the cabinet for containment assessment.
Site Installation and System Diagnostics
Site Installation Assessment Tests
Tests to verify proper installation and alarm activation for safety and operation.
Pharmacy Application Cleanliness Test
Testing for air cleanliness classification required for pharmacy applications per USP797.
Diagnostics and Troubleshooting
Using diagnostic menus to test system components like blowers, sensors, and I/O.
Main Control Board and Sensor Maintenance
Main Control Board Replacement
Steps for replacing the main control board assembly.
Digital Airflow Sensor Description
Description and replacement procedures for the digital airflow sensors.
Error Message Troubleshooting Guide
A guide to identifying and resolving common error messages displayed by the cabinet.
Service Menu and Optional Features
Blower Options and Manual Control
Options for controlling the blower, including manual mode and lockout features.
Certification Date Management
Setting and updating the cabinet certification date and managing re-certification reminders.
Interlock Features Configuration
Enabling or disabling interlock features that link component operations for safety.
Airflow Sensor Performance Verification
Run Mode Sensor Performance Check
Verifying airflow sensor performance by observing changes during normal operation.
Optional Equipment and System Requirements
Ultraviolet (UV) Light System
Information on the optional UV light system, including its purpose, operation, and safety.
UV Light Operation and Safety
How to operate the UV light system and the necessary safety precautions.
UV Light Precautionary Measures
Important safety precautions to take when using the ultraviolet light system.
Electrical and Environmental Requirements
Electrical Power Requirements
Details on voltage, frequency, phase, and amperage requirements for the cabinet.
Operational Performance Conditions
Environmental conditions such as temperature and humidity for optimal cabinet performance.
Chemical Exposure and Material Compatibility
Information on chemical exposure limits and material compatibility for cleaning agents.
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