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Summary of Contents for illumina DRAGEN v4
- Page 1 Illumina DRAGEN Server v4 Site Prep and Installation Guide ILLUMINA PROPRIETARY Document #200015717 v03 January 2023 For Research Use Only. Not for use in diagnostic procedures.
- Page 2 Illumina DRAGEN Server v4 Installation Guide This document and its contents are proprietary to Illumina, Inc. and its affiliates ("Illumina"), and are intended solely for the contractual use of its customer in connection with the use of the product(s) described herein and for no other purpose.
- Page 3 Illumina DRAGEN Server v4 Installation Guide Revision History Document Date Description of Change 200015717 v03 January 2023 Removed the requirement for a mouse during installation Updated 10 GB SFP+ port interface name Added the following information: • Steps to activate the DRAGEN software license •...
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Page 4: Table Of Contents
Illumina DRAGEN Server v4 Installation Guide Table of Contents Revision History Overview Site Preparation Delivery and Setup Facility Requirements Electrical Requirements Environmental Considerations Safety & Compliance Safety Considerations and Markings Compliance and Regulatory Markings Set Up the DRAGEN Server Mount the Server... -
Page 5: Overview
Illumina DRAGEN Server v4 Installation Guide Overview This resource provides instructions for setting up the Illumina® DRAGEN Server™ , including preparing your site for installation and operation. The CentOS Project will discontinue support of CentOS 7 on June 30, 2024. As a result, support for CentOS 7 on the DRAGEN Servers will end. -
Page 6: Site Preparation
Illumina DRAGEN Server v4 Installation Guide Site Preparation This section provides specifications and guidelines for preparing your site for installation and operation of the DRAGEN Server. • Laboratory space requirements • Electrical requirements • Environmental considerations Delivery and Setup The DRAGEN Server is unpacked and installed by the customer. The space must be ready before delivery. -
Page 7: Facility Requirements
Illumina DRAGEN Server v4 Installation Guide Facility Requirements Use the specifications and requirements provided in this section to set up your lab space. Equipment Dimensions Measurement Dimension Height 8.8 cm (3.46 in) Width 43.8 cm (17.24 in) Depth 76.0 cm (29.924 in) Weight 23 kg (50.7 lb) -
Page 8: Environmental Considerations
Illumina DRAGEN Server v4 Installation Guide For 100–240 Volts AC, your facility must be wired with a minimum 15 amp grounded line with proper voltage. An electrical ground is required. If the voltage fluctuates more than 10%, a power line regulator is required. - Page 9 Illumina recommends using a user- supplied uninterruptible power supply (UPS). Illumina is not responsible for data loss caused by interrupted power, regardless of whether the DRAGEN Server is connected to a UPS. Standard generator- backed power is often not uninterruptible, so a brief power outage occurs before power resumes.
- Page 10 Illumina DRAGEN Server v4 Installation Guide North America APC Japan APC Model # International APC Model # SMT3000RMJ2U Specification Model # SMT3000RM2U SMT3000RMI2U Maximum Output 2700 W 2880 VA 2400 W 2400 VA 2700 W 3000 Capacity Input Voltage 120 VAC...
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Page 11: Safety & Compliance
Illumina DRAGEN Server v4 Installation Guide Safety & Compliance This section provides important safety information pertaining to the installation and operation of the DRAGEN Server. This section includes product compliance and regulatory statements. Read this section before performing any procedures on the server. -
Page 12: Set Up The Dragen Server
Illumina DRAGEN Server v4 Installation Guide Set Up the DRAGEN Server This section provides information on installing the DRAGEN Server. Before beginning, make sure that you have all the components and your facility meets the requirements. The following components are not included with the DRAGEN Server and are required to set up the server: •... - Page 13 Illumina DRAGEN Server v4 Installation Guide Align the key slots to the T studs on the sides of the server, and then slide the mounting bracket back to lock into place. Repeat to attach the mounting bracket on the other side.
- Page 14 Illumina DRAGEN Server v4 Installation Guide Align the rail assembly into the desired front server rack brackets, and then flip the lock mechanism forward to lock the rail assembly into place. Repeat for the other rail. Install the Server in the Rack Two people are recommended for moving the server.
- Page 15 Illumina DRAGEN Server v4 Installation Guide Document #200015717 v03 For Research Use Only. Not for use in diagnostic procedures.
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Page 16: Server Ports
Illumina DRAGEN Server v4 Installation Guide Server Ports The following figure indicates the port location on the rear of the server for each cable required when installing the Illumina DRAGEN Server. A. VGA port (monitor) B. 1 GB Ethernet port with interface name enp5s0 (BMC) C. -
Page 17: Shut Down The Server
Illumina DRAGEN Server v4 Installation Guide The DRAGEN Server performs an additional boot cycle when first turned on. The boot cycle unlocks the drive. Allow the DRAGEN Server to perform the boot cycle without user input. Shut Down the Server You can shut down the DRAGEN Server directly from the command line. -
Page 18: Configure Settings
User Behavior on page 14 for more information on appropriate use. Antivirus Software Illumina does not recommend running any virus scanners on the DRAGEN Server. Virus scanners often impact the performance of High- Performance Computing (HPC) systems. Restricted Ports and Authentication Outbound Connections lus.edicogenome.com port 80... -
Page 19: Network Considerations
Use the Network Manager Text User Interface (NMTUI) to configure the IP address, gateway, DNS server, and additional options for your connection. Log in as root using the default password: Hello@Illumina!. The system prompts users to reset the password upon first login. - Page 20 Illumina DRAGEN Server v4 Installation Guide Select Edit a connection. Navigate to the active connection, and then select Edit. Select Show next to IPv4 Configuration or IPv6 Configuration. Select Automatic to choose one of the following IP configurations: • To remove the IP configuration, select Disabled.
- Page 21 Log in as root user using the root password provided in the DRAGEN Server welcome email. If you have not received your sign in credentials, contact Illumina Customer Service. If signing in for the first time, reset your password.
- Page 22 Restarts the network manager service. Allow Root Log in by SSH To access the Illumina DRAGEN Server remotely, you must enable root log in by SSH connections. By default, root log in attempts from SSH connections are blocked. Log in as root.
- Page 23 Illumina DRAGEN Server v4 Installation Guide Restart sshd as follows. systemctl restart sshd Document #200015717 v03 For Research Use Only. Not for use in diagnostic procedures.
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Page 24: Activate The Dragen Software License
Illumina DRAGEN Server v4 Installation Guide Activate the DRAGEN Software License The Illumina DRAGEN Server ships with temporary short- term software licenses. The license activation process differs depending on whether the server is connected to the internet or is offline. Root/sudo access is required to run the commands below. -
Page 25: Running The System Check
Confirm that the license has been updated. Enter: /opt/edico/bin/dragen_lic Running the System Check After turning on the server, make sure that your Illumina DRAGEN Server is functioning properly by running the following self- test script: /opt/edico/self_test/self_test.sh The self- test script performs the following actions: •... - Page 26 If the output BAM file does not match the expected results, the last line of the previous text displays the following text: SELF TEST RESULT : FAIL If you receive a FAIL result after running the test script immediately after turning on your Illumina DRAGEN Server, contact Illumina Technical Support. Document #200015717 v03...
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Page 27: Verify And Install The Dragen Software
If prompted to switch to a new hardware version, enter y. If the hardware upgrade process is interrupted, perform the software install steps again. If the DRAGEN software is not functional after the second install attempt, contact Illumina Technical Support. - Page 28 Document #200015717 v03 Illumina 5200 Illumina Way San Diego, California 92122 U.S.A. +1.800.809.ILMN (4566) +1.858.202.4566 (outside North America) techsupport@illumina.com www.illumina.com For Research Use Only. Not for use in diagnostic procedures. © 2023 Illumina, Inc. All rights reserved.
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