How It Works - Tivic Health ClearUP User Manual

How It Works

ClearUP works in several ways
• Safe microcurrent is emitted from the tip of the
unit to sinus nerve fibers under the skin.
• Electrical stimulation of nerves reduces feelings
of sinus pain for up to 6 hours according to our
clinical study.
• Published research has shown that electrical
stimulation can also shrink swollen tissue;
swelling is often a key cause of nasal and
sinus symptoms.
Note: ClearUP must be self-administered and cannot be applied to
another person. This is due to the electrical circuit design. The hand
holding the device completes the electrical path
1. Goldsobel, Alan B., Niveditha Prabhakar, and Blake T. Gurfein.
"Prospective trial examining safety and efficacy of microcurrent
stimulation for the treatment of sinus pain and congestion."
Bioelectronic Medicine 5.1 (2019): 1-9.
2. Mandel, Yossi, et al. "Vasoconstriction by electrical stimulation:
new approach to control of non-compressible hemorrhage."
Scientific reports 3 (2013).
3. Franco, O. S., et al. "Effects of different frequencies of
transcutaneous electrical nerve stimulation on venous vascular
reactivity." Brazilian Journal of Medical and Biological Research
47.5 (2014): 411-418.
4. Malm, L. "Stimulation of sympathetic nerve fibres to the nose in
cats." Acta oto-laryngologica 75.2-6 (1973): 519-526.
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Nerve
Pathways