PreOmics BeatBox User Manual
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PreOmics BeatBox User Manual

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Document Information
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UBJECT
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:
RODUCT
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OCUMENT
YPE
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OCUMENT
AME
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OCUMENT
UMBER
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EVISION
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OMPANY
Document Change Control
Adaptations and updates of the present document are a consequence of technical improvements
and amendments of the BeatBox. Any changes within this document are to be controlled.
Document revisions
R
D
EVISION
OCUMENT
01
UM-BB-1001-01
02
UM-BB-1001-02
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UM-BB-1001-03
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UM-BB-1001-04
UM-BB-1001-04
D
ESCRIPTION
BeatBox
User Manual
BeatBox User Manual
UM-BB-1001
04
2022-08-04
PreOmics GmbH
F
N
ILE
AME
R
EASON FOR CHANGE
First Release
Added Information: PSU
(Power Supply Unit)
Type; Operating
Conditions
Information added for
BeatBox Tissue Kit 24x;
URL of BeatBox user
manual added;
B
VALID FROM
Y
NoKa
2022-03-01
NoKa
2022-03-04
NoKa
2022-07-19
NoKa
2022-08-04

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Summary of Contents for PreOmics BeatBox

  • Page 1 2022-08-04 PreOmics GmbH OMPANY Document Change Control Adaptations and updates of the present document are a consequence of technical improvements and amendments of the BeatBox. Any changes within this document are to be controlled. Document revisions VALID FROM EVISION OCUMENT...
  • Page 2 User Manual BeatBox by PreOmics UM-BB-1001-04...

  • Page 3: Table Of Contents

    Table of content Warning and Information symbols ....................4 Introduction ..........................5 About this manual ....................... 5 Intended use of the BeatBox ................... 5 Requirements for BeatBox users ..................6 Copyright protection ......................6 General Safety Instructions ...................... 7 Proper use ..........................7 Electrical safety ........................
  • Page 4 Mechanical data and hardware features ..............32 Declaration of Conformity ....................32 Waste Electrical and Electronic Equipment (WEEE) ..........32 FCC Declaration ........................ 33 Liability Clause ........................34 Appendix B – BeatBox Instrument - Scope of delivery ............ 35 Version history .......................... 36 UM-BB-1001-04...

  • Page 5: Warning And Information Symbols

    Warning and Information symbols Before using the BeatBox, it is essential that you read this user manual carefully and pay attention to the safety information. The instructions and safety information in the user manual must be followed to ensure safe operation of the instrument and to maintain the instrument in a safe condition.

  • Page 6: Introduction

    About this manual This manual describes the features and safe operation of the BeatBox instrument. It is an integral part of the BeatBox delivery. Before using the BeatBox, it is essential that you read this user manual carefully and pay attention to the safety information.

  • Page 7: Requirements For Beatbox Users

    Trained and authorized by only PreOmics. 1.4 Copyright protection This manual may not be used or reproduced in any way without the express written consent of PreOmics GmbH. Copyright © 2022 PreOmics PreOmics GmbH, Am Klopferspitz 19, D-82152 Planegg/Martinsried GmbH. All rights resereved.

  • Page 8: General Safety Instructions

    Avoid spilling water or chemicals onto the BeatBox. Damage caused by water or chemical spillage will void your warranty. In case of emergency, power OFF the BeatBox at the power switch located at the back of the instrument and unplug the power cord from the power outlet.
  • Page 9 PreOmics kits only. Use of other reagents and substances may lead to fire or explosion. If hazardous material is spilled on or inside the BeatBox, the user is responsible for carrying out appropriate decontamination according with the safety datasheets of the hazardous materials used.

  • Page 10: Electrical Safety

    To check the recommended supply voltage, refer to the specifications indicated in the type plate of the instrument. To ensure satisfactory and safe operation of the BeatBox, follow these guidelines: Do not adjust or replace internal parts of the instrument.

  • Page 11: Environment

    2.3 Environment 2.3.1 Operating conditions DANGER Explosive atmosphere [D3] The BeatBox is not designed for use in an explosive atmosphere. CAUTION Damage to the instrument [C6] Direct sunlight may bleach parts of the instrument and cause damage to plastic parts.

  • Page 12: Chemicals

    † documents. WARNING Toxic fumes [W10] Do not use bleach to clean or disinfect the BeatBox. Bleach in contact with salts from the buffers can produce toxic fumes. WARNING Toxic fumes [W11] Do not use bleach to disinfect used labware. Bleach in contact with salts from the buffers used can produce toxic fumes.

  • Page 13: Waste Disposal

    Refer to your local safety regulations for proper disposal procedures. 2.7 Mechanical hazards The garage of the BeatBox must remain closed during operation of the instrument. Only lift the garage when instructed to do so by the instruction for use.

  • Page 14: Maintenance Safety

    Clean spillage on the instrument surfaces immediately after the run. CAUTION Damage to the instrument [C10] Do not use spray bottles containing alcohol or disinfectant to clean surfaces of the BeatBox. Spray bottles should be used only to clean items that have been removed from the instrument. UM-BB-1001-04...

  • Page 15: Symbols On The Beatbox

    2.10 Symbols on the BeatBox Symbol Location Description Type plate on the back of the Device classified under FCC part instrument. 15 follows requirements specified by Federal Communications Commission. Type plate on the back of the CE marking to indicate instrument.

  • Page 16: Beatbox Overview

    The user selects a predefined setting on the touchscreen and loads labware, including samples and reagents, into the BeatBox garage. The user then closes the instrument by putting the garage into the BeatBox and starts the protocol, which provides all necessary commands for tissue homogenization. A BeatBox run could vary from 30 seconds to 10 minutes.

  • Page 17: Beat Box Rear View

    3.2 Beat Box Rear View Cooling air outlet Power inlet LAN port (for service only) ON/OFF switch D-Sub socket (for service only) CAUTION Damage to the instrument [C11] Do not close the cooling air inlet or outlet with an obstacle as it will distort the instrument heat management.

  • Page 18: Beatbox Garage

    3.3 BeatBox garage The BeatBox garage houses the sample plate and the corresponding adapter. For further details please refer to the corresponding kit manual and the BeatBox Quick Start manual. Note: The garage must be inserted into the BeatBox before a BeatBox run can be started.

  • Page 19: Beatbox Tube And Plate Adapter

    BeatBox Accessory Box). The Tube Adapter is required for the BeatBox Tissue Kit 24x and the Plate Adapter for the Beat Box Tissue Kit 96x. For more details, please refer to the corresponding protocols and quick-start manuals of the kits.

  • Page 20: Safety Opening Tool

    The garage can be opened with the pair of unlock tools. This security feature is for taking samples out of the garage in case the garage could not be opened via the touch screen. Note: If the tools are used to open the garage during a processing run the BeatBox stops immediately and the samples may be destroyed.

  • Page 21: Site Requirements

    Ensure that the workbench is dry, clean and vibration-proof and has additional space for accessories. Ensure that the BeatBox is positioned so that it is easy to access the power connector and the power switch at the back of the instrument at all times, and that it is easy to power the instrument OFF and disconnect it.

  • Page 22: Unpacking The Beatbox

    PreOmics Technical Service. 2. Open the transportation box. It contains two boxes: The utilities box and the BeatBox box. 3. When lifting the BeatBox out of the box, slide your fingers under both sides of the unit and keep your back straight.
  • Page 23 Make sure that the BeatBox switch is in OFF position ON/OFF – switch: OFF Connect the coaxial low voltage connector to the BeatBox DC power inlet DC power inlet (Male) BeatBox ON/OFF – switch: OFF...
  • Page 24 After the BeatBox has been switched on the following boot screen is displayed for about 20 seconds: Boot screen after switching the BeatBox on After the boot process is finished the GUI of the BeatBox appears: BeatBox graphical user interface (GUI)

  • Page 25: Operating Procedures

    4 Operating Procedures This section describes how to operate the BeatBox. Important: The BeatBox is designated for use with PreOmics Kits developed for the BeatBox only. Use of other types of kits or chemistries will void your warranty. CAUTION Damage to the instrument...
  • Page 26 When the garage locks are open the garage can be taken out of the BeatBox and the plate adapter and sample plate can be placed into the garage. For further information on how to prepare the sample plate or tubes, please refer to the manual of your PreOmics kit (BeatBox Tissue Kit 96x or 24x format).
  • Page 27 10 minutes You can interrupt a BeatBox run by pressing the STOP icon. The processing time is reset to the default value of 10 minutes. There is no option to just pause the run. Once the BeatBox run is finished remove the garage and follow the kit protocol accordingly (BeatBox Tissue Kit 96x or 24x format).
  • Page 28 Servicing of the BeatBox must only be performed by a PreOmics Service specialist. If the garage is opened with the unlock tool or any other tool while the BeatBox is running, the BeatBox stops immediately with the following warning screen: Press the OK button to acknowledge the error message.

  • Page 29: Beatbox Software

    Some of the solvents used with the instrument are volatile. Use the instrument only with adequate ventilation according to the applicable Safety Data Sheets (SDS), OSHA or ACGIH documents. † 4.1 BeatBox software The BeatBox software uses open-source software. The corresponding licenses can be found at https://www.preomics.com/beatbox-software-license-files. UM-BB-1001-04...

  • Page 30: Troubleshooting

    5 Troubleshooting 5.1 PreOmics Technical Services Please do not hesitate to contact PreOmics support in case unexpected errors occur. Phone: +49-89-2314163-0 E-Mail: beatboxsupport@preomics.com UM-BB-1001-04...

  • Page 31: Glossary

    Power Switch A button located at the back of the BeatBox in the bottom-left corner. It allows the user to switch the BeatBox on and off; inner position (I) pressed is ON and outer position (O) pressed is OFF. External Power Supply Unit.

  • Page 32: Appendix A - Technical Data

    7 Appendix A – Technical data Operating conditions External Power supply Input 100–240 V AC, 50/60 Hz. Output: 24VDC BeatBox 24VDC; Power: 50W; Overvoltage category Max. current 1.3 A at 100 VAC Operating 18 to 28ºC (64.4 to 82.4ºF) temperature Operating humidity 15–75% (noncondensing)

  • Page 33: Mechanical Data And Hardware Features

    7.5 Declaration of Conformity Name and address of the legal manufacturer: An up-to-date declaration of conformity can be requested from PreOmics. 7.6 Waste Electrical and Electronic Equipment (WEEE) This section provides information about disposal of waste electrical and electronic equipment by users.

  • Page 34: Fcc Declaration

    To prevent fires, tape battery terminals and/or place lithium-ion batteries in separate plastic bags. Recycling can be provided by PreOmics upon request at additional cost. In the European Union, in accordance with the specific WEEE recycling requirements and where a replacement product is being supplied by PreOmics, free recycling of its WEEE-marked electronic equipment is provided.

  • Page 35: Liability Clause

    7.8 Liability Clause PreOmics shall be released from all obligations under its warranty in the event repairs or modifications are made by persons other than its own personnel, except in cases where the Company has given its written consent to perform such repairs or modifications.

  • Page 36: Appendix B - Beatbox Instrument - Scope Of Delivery

    8 Appendix B – BeatBox Instrument - Scope of delivery Product Content Quantity BeatBox BeatBox Instrument (1-year warranty on parts and labor) Accessory Box BeatBox Roller Rod Magnet Gyuto Bead Collection Rack Plate Adapter for BeatBox Tissue Kit 96x Tube Adapter for BeatBox...

  • Page 37: Version History

    First release BeatBox User Manual 2022-03-04 PSU (Power Supply Unit) Type Operating conditions BeatBox User Manual 2022-07-19 Information added for BeatBox Tissue Kit 24x; URL of BeatBox user manual added; BeatBox User Manual 2022-08-04 URL of BeatBox user manual added; UM-BB-1001-04...

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