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UGO BASILE - I
E C T UNIT
5 7 8 0 0
Cat.
1
GENERAL
The ECT Apparatus is specially designed for neurochemical and neuropharmacological
research. It is particularly useful for:-
a)
general screening of potentially neurotropic substances
b)
evaluating the depressant or stimulating action of drugs on the CNS
c)
endocrinological investigations on the relationship between the nervous sys-
tem and the hypophysis.
A constant current output is used which ensures reproducible results and accurate de-
termination of the EC threshold while also pinpointing any variation in the threshold
brought about by drugs having specific action on the cortex and subcortical regions.
The shock parameters have been selected after consulting the most recent literature, in
order to determinate the range of requirements likely to be needed when operating with
mice and rats.
The solid state circuit supplies from 1 to 299 rectangular pulses per second, .1 to .9 ms in
width, for duration variable from .1 to 9.9 seconds. Shock current can be accurately pre-
set on a scale of 1-99 mA.
The actual intensity of the shock depends on the current which runs through the subject's
body. The instrument automatically adjusts the current to the value preset by the opera-
tor, irrespective of the animal's skin resistance and skin/electrode interface conditions.
Accordingly, the intensity of the current running through each animal in any given ex-
perimental group is identical.
The standard auricular electrodes supplied allow a single operator to deliver shock to a
number of animals in a short time. The special output circuit enables any type of elec-
trode to be used, e.g., corneal or temporal electrodes, which can be provided on request.
1.1
Instrument description
The instrument consist of:-
1)
a constant current Pulse Generator 57800-001, which comprises:-
a pulse train generator
a power amplifier
TALY
Page 1
57800 Instruction Manual (Rev. 1)
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