Genfine Purifier 32 User Manual
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GENFINE
Purifier 32
User Manual V2.2
GENFINE Biotech (Changzhou) Co., Ltd.

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Summary of Contents for Genfine Purifier 32

  • Page 1 GENFINE Purifier 32 User Manual V2.2 GENFINE Biotech (Changzhou) Co., Ltd.
  • Page 2: Table Of Contents

    目录 Chapter 1 Product Introduction......................1 1.1 Product Name........................1 Automatic nucleic acid extractor....................1 1.2 Model.............................1 Purifier 32............................1 1.3 Intended Use..........................1 1.4 Working Principle........................1 Chapter 2 Function Introduction...................... 1 2.1 Main Components......................... 1 2.2 Magnetic Bead Processing Principle..................3 Chapter 3 Installation and Packaging....................5 3.1 Delivery Check........................5...
  • Page 3 7.7 More information........................ 21 7.8 Safety and User Guide......................21 Chapter 8 Manufacturer and Medical Device Information............23 Chapter 9 Order Information......................24 9.1 Purifier 32 configuration.....................24 9.2 List of accessories and consumables.................. 24 9.3 List of kits..........................24 Appendix A Certificate of Decontamination................. 26...
  • Page 4: Chapter 1 Product Introduction

    The patented technology of the Purifier 32 system is based on the use of magnetic rods and microwell plates with disposable and specially designed magnetic tip combs. The instrument may work without any distribution or suction parts or devices.
  • Page 5 See Figure 2-2 for the rear view of Purifier 32. Figure 2-2. Purifier 32 Rear View Purifier 32 (Figure 2-1) has 2 microwell plate positions. The magnetic tip combs match the microwell plate. During each step, the microwell plate remains stationary and the only component that moves is the magnetic head with magnetic tip comb and magnetic rod.
  • Page 6: Magnetic Bead Processing Principle

    disposable plastic magnetic tip comb. 2.2 Magnetic Bead Processing Principle Figure 2-3. Magnetic Bead Processing Principle Sketch Map 2.2.1 Magnetic bead processing Magnetic bead processing can be divided into four separate steps: Bind magnetic beads  Release magnetic beads  Rinse magnetic beads ...
  • Page 7 Figure 2-4 Concentration Process in Magnetic Bead Processing 2.2.6 USB Port There is a USB port on the front panel for updating the software of the touch screen and motherboard. 2.2.7 Consumables See "Accessory and Consumables List" for details and ordering information about Purifier 32's plastic consumables, such as deep-well plates, magnetic tip comb, HEPA filters and UV lights.
  • Page 8: Chapter 3 Installation And Packaging

    3.2 Environment Requirement When installing Purifier 32, avoid placing it in the places where there is a lot of dust, vibration, strong magnetic field, direct sunlight or ultraviolet radiation, airflow, high humidity or high temperature fluctuation.
  • Page 9: Installation Settings

    on the back of the instrument (Figure 2-2);  Do not smoke or eat or drink while using this device;  Clean hands thoroughly after handling the buffer solution;  Follow regular laboratory procedures for handling samples that may be dangerous; ...
  • Page 10 Figure 3-2.Schematic Diagram After Removing the Set Screw of Magnetic Rod Holder 3.4.2 Installation of 96-well plate The circular bottom of the 96-well plate with square hole and circular bottom just fits with the concave clamping position of the heating tank; the heating tank is located under the 2/6 and 8/12 vertical row holes of the 96-well plate.
  • Page 11: Power Connection

    3-4. Effect Diagram after Installation of 96-Well Plate and Magnetic Tip Comb 3.5 Power Connection Connect the power connector: Warning Make sure that the power switch on the rear panel (Figure 2-2) is in the "O" position. Never connect an ungrounded power outlet. Do not use any power cord other than the one provided by the manufacturer.
  • Page 12 3-5. Inside schematic diagram of packaging box Page 9 of 27...
  • Page 13: Chapter 4 Instructions For Use

    Chapter 4 Instructions for Use 4.1 Starting Before turning on Purifier 32, make sure that the voltage on the label which is on the left bottom of the back panel (Figure 2-2) matches the local voltage. Warning Never operate the instrument on an ungrounded electrical outlet.
  • Page 14 Users can select any file in the table, for example by clicking the "DNA" button to enter the list of programs. Click the program you want to run, and click "Select" to enter the program details interface. The program detail interface displays the step number, board position number, item name, time, volume, temperature and other parameters.
  • Page 15 4.2.3 New Program Creation Click "New Program" on the main interface to create a new programs according to the customer’s requirements. Enter the program name and select the program type. Click “Back” to return to the main screen. Click "Next" to enter the program editing interface. Click "Add"...
  • Page 16 according to the volume filled in. Click , to return to the program details. After setting, click "Next" to enter the parameter setting interface. The heating temperature and time are selected according to the requirements of the experiment. The temperature setting range is 0-99 ° C, and the temperature can be switched. The entry position of the deep-well plate is the position where the magnetic tip comb enter the deep-well plates for mixing;...
  • Page 17: Shutting Down

    1. Press the power switch (Figure 2-2) on the rear panel of the instrument to the OFF position to turn off Purifier 32. It is recommended to turn off the instrument at night and on weekends. 2. Wipe the surface of the platform and adjacent instrument with a soft cloth or paper towel with distilled water, mild detergent (SDS, sodium lauryl sulfate) or soap solution.
  • Page 18: Chapter 5 Care And Maintenance

    If necessary, clean the outer surface of the instrument and the plate with clean low-pressure compressed air, or a cloth dampened with water or a mild detergent. Although Purifier 32 is made of high-quality materials, you must remove the spilled salt solution, chemical solvent, acid or alkaline solution from the surface immediately to prevent damage to the instrument.
  • Page 19: Waste Disposal

    Warning The product has a strong permanent magnet. This product should not be used by people wearing pacemakers or metal prostheses. Prosthetic devices such as pacemakers or prostheses may be affected or damaged by close contact with strong magnetic fields. 5.4 Waste disposal Follow the specific regulations of laboratories and the country for handling biological waste.
  • Page 20: Packaging For Repair

    5.9 Disposal of the instrument If Purifier 32 must be discarded, please follow the specific regulations of the laboratory and the country for the treatment of biological waste. The disposal of the instrument is carried out in accordance with the laws and regulations of the local authorities on the recycle of electronic equipment and waste.
  • Page 21 decontamination procedures. Page 18 of 27...
  • Page 22: Chapter 6 Technical Parameters

    Chapter 6 Technical Parameters 6.1 General Parameters As part of our continuous product development plan, the manufacturer reserves the right to change any parameters without prior notice. General parameters are shown in Table 6-1. Table 6-1 General parameters General parameters Overall size - Device 405 mm (width) x350 mm (length) x465 mm...
  • Page 23: Safety Parameters

    31 ℃ and the humidity drops linearly to 50% at 40℃. AC power fluctuation Not more than ±10% of the marked voltage 6.4 Compliance Purifier 32 meets the following compliance YY 0505-2005/IEC 60601-1-2:2001 GB 4793.1-2007/IEC 61010-2:2001 Page 20 of 27...
  • Page 24: Chapter 7 Other Information

    This instruction is for end-users, such as scientific researchers and laboratory technicians; it provides basic information about the 32-channel automatic nucleic acid extraction and purification instrument (referred to as Purifier 32), including the installation and operation of the instrument. 7.7 More information For the latest information on products and services, please visit our website: http://www.genfine.com/.
  • Page 25 (Figure 2-1).  Do not force the microplate onto the plate.  Purifier 32 meets the Medical electrical equipment - Part 1-2: General requirements for safety. Please comply with appropriate laboratory safety precautions, such as wearing protective clothing and certified laboratory safety procedures.
  • Page 26: Chapter 8 Manufacturer And Medical Device Information

    Chapter 8 Manufacturer and Medical Device Information Manufacturer: GENFINE BIOTECH (CHANGZHOU) CO., LTD Production record certificate No.: SCSYJXSCB 20180017 Medical device production record number: SCXB 20190274 Manufacturer Address: 4th Floor, Block E4, No. 9, Changyang Road, West Taihu Science and Technology Industrial Park, Changzhou City, Jiangsu Province...
  • Page 27: Chapter 9 Order Information

    Purifier 32 (English) Purifier 32-03 Purifier 32 (Custom) 9.2 List of accessories and consumables Table 9-2 List of accessories and consumables used with Purifier 32. Table 9-2 Item number of accessories and consumables Inventory name New Item No. JF 8 magnetic tip comb...
  • Page 28 Table 9-3 Product information of nucleic acid purification magnetic beads New Item Product name FineMag Blood Spot Genomic DNA Kit M101 FineQuick Blood Genomic DNA Kit M103 FineMag Plasma Circulating DNA Maxi Kit M107 FineMag Universal Genomic DNA Kit M202 FineMag Plant Genomic DNA Kit M302 FineMag Swab Genomic DNA Kit...
  • Page 29: Appendix A Certificate Of Decontamination

    Appendix A Certificate of Decontamination Name:______________________________________________________ Address:______________________________________________________ Telephone / Fax:_________________________________________________ Device:__________________ No.: __________________________ A) I confirm that the returned items are not contaminated with liquid, toxic, carcinogenic or radioactive substances or any other harmful substances. B) I confirm that the returned items have been decontaminated and can be processed without affecting the health of the personnel.
  • Page 30: Appendix B System Log

    Appendix B System Log Device name and number User Date Note Page 27 of 27...
  • Page 31 GENFINE Biotech (Changzhou) Co., Ltd. www.genfine.com marketing@genfine.com Page 28 of 31...

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