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Harvard Apparatus VentElite 55-7040 User Manual

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User's Manual
VentElite
55-7040
Publication 5420-009 REV-1.0

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Summary of Contents for Harvard Apparatus VentElite 55-7040

  • Page 1 User’s Manual VentElite 55-7040 Publication 5420-009 REV-1.0...

  • Page 2: Table Of Contents

    Table of Contents SUBJECT PAGE # Warranty & Repair Information Manual Description Warranty General Safety Information Technical Specifications Introduction Installation Initial Setup Location Requirements Typical Operation Ventilator Connections Operation Getting Started Mode Selection Volume Mode Pressure Mode Setting the Respiration Rate Setting the Tidal Volume Setting the Peak Inspiratory Pressure (PIP) I:E Ratio...

  • Page 3: Warranty & Repair Information

    Harvard Apparatus warranties this instrument for a period of two years from date of purchase. At its option, Harvard Apparatus will repair or replace the unit if it is found to be defective as to workmanship or materials. This warranty does not extend to damage resulting from misuse, neglect or abuse, normal wear and tear, or accident.

  • Page 4: General Safety Information

    General Safety Summary Please read the following safety precautions to ensure proper use of your VentElite. If the equipment is used in a manner not specified, the protection provided by the equipment may be impaired. To Prevent Hazard or Injury Use Proper Power Supply The unit is supplied with an approved power supply and line cord.
  • Page 5 General Safety Summary Place Product in Proper Environment Review the operating manual for guidelines for proper operating environments. Observe All Warning Labels on Product Read all labels on product to ensure proper usage. CAUTION Protective Refer to Manual Ground Terminal CAUTION: FOR RESEARCH USE ONLY.

  • Page 6: Technical Specifications

    Technical Specifications Suggested Weight Range 10 g to 1 kg Species Mouse to Guinea Pig Port Sizes To Animal and Source 3.6-3.8 mm (0.14-0.15 in) From Animal and Exhaust 4.0 mm (0.16 in) Control Modes Volume or Pressure Tidal Volume Range 50 µl to 5 ml Tidal Volume Accuracy 0.1 µl...
  • Page 7 Method of Operation Continuous Classification Class I Pollution Degree Installation Category Supplier Name Harvard Apparatus Supplier Address 84 October Hill Road, Holliston, MA 01746 Regulator Certifications CE, ETL (UL, CSA), WEEE, & EU RoHS Safety Declarations ANSI/UL 61010-1; CAN/CSA C22.2. No. 61010-1;...

  • Page 8: Introduction

    Introduction Theory of Operation The VentElite was designed for animal research applications and is intended for use on subjects ranging in size from mice to guinea pigs. The design goal of this ventilator was to maintain versatility and ease of use while fostering safe and physiologically accurate mechanical ventilation conditions.
  • Page 9 Features Volume Control Mode The VentElite delivers a known volume of gas to the subject on each inspiration stroke. Respiration frequency and I:E ratio determine the amount of time for inspiration and expiration phases. Pressure Control The ventilator delivers gas to the subject until the user- Mode defined pressure limit is reached.

  • Page 10: Installation

    Installation Front and Back of the VentElite Initial Setup 1. Remove unit from the box 2. Remove foam-packing inserts from both ends of the ventilator 3. Locate and carefully remove the power supply and line cord from the shipping material 4.

  • Page 11: Typical Operation

    Installation Typical Operation The VentElite is designed to respirate small animals with a body mass ranging from 10 g to 1 Kg. It can operate at respiration rates of 10 to 300 breaths per minute (bpm) and can deliver tidal volumes of 50 µl to 5 ml. The VentElite is designed for use in a typical laboratory, operating room, or any other well-ventilated, nonexplosive environment.
  • Page 12 Installation Airway Tubing Connections Source Flow of gas used by VentElite for inspiration. Connect to the source of inspiration gas or leave disconnected to use room air for ventilation. To Animal Flow of gas from ventilator to the animal. From Animal Flow of expired gas from animal to ventilator.

  • Page 13: Operation

    Operation GETTING STARTED 1. Turn VentElite on and wait for the valve assembly to return to the home position Mode Selection Volume Mode 1. From the Settings Screen enter the Mode Selection Screen by selecting the Mode button 2. Select Volume Mode 3.

  • Page 14: Pressure Mode

    Operation Pressure Mode 1. From the Settings Screen enter the Mode Selection Screen by selecting the Mode button 2. Select Pressure Mode 3. Accept the changes made by pressing the and return to the main screen OR Cancel the changes made by pressing the and go back to the main screen Setting the Respiration Rate 1.

  • Page 15: Setting The Tidal Volume

    Operation Setting the Tidal Volume (Volume Mode only) 1. Set the tidal volume by selecting the Tidal Volume button in the top right corner of the display screen 2. Use the Unit Selection button under the selected volume box to toggle between µl and ml 3.

  • Page 16: Setting The Peak Inspiratory Pressure (Pip)

    Operation Setting the Peak Inspiratory Pressure (PIP) 1. Set the peak inspiratory pressure (PIP) by selecting the PIP button on the right side of the display screen (second button from the top) 2. Use the keypad, or up and down arrows, to enter the desired PIP from 1 to 50 cmH 3.

  • Page 17: Sigh Breath

    Operation I:E Ratio (continued) 2. Use the keypad, or up and down arrows, to enter the desired I:E ratio from 20:80 to 80:20 3. Accept the changes made by pressing the and return to the main screen OR Cancel the changes made by pressing the and go back to the main screen Note: Depending on the respiration rate, the acceptable I:E range may differ Sigh Breath...

  • Page 18: Inspiratory/Expiratory Hold

    Operation Inspiratory/Expiratory Hold 1. Set the Inspiratory Hold by selecting the Insp. Hold button located on the bottom of the display screen 2. Use the keypad, or up and down arrows, to enter the desired Inspiratory Hold time from 0 to 60 seconds 3.

  • Page 19: Positive End-Expiratory Pressure (Peep)

    Operation Positive End-Expiratory Pressure (PEEP) 1. To set a PEEP select the PEEP button on the right side of the display screen 2. Use the keypad, or up and down arrows, to enter the desired PEEP from 0 to 10 cmH 3.
  • Page 20 Operation Audible Alarms The VentElite has several Audible Alarms that the user can choose to mute should they wish. These alarms are: • Over Pressure: Indicates the PIP is greater than the pressure readback by more than 10% • Under Pressure: Indicates that the pressure readback at end of inhalation is 80% less than the set PIP •...

  • Page 21: Backlight

    Operation Backlight 1. In the Settings screen, select Backlight 2. Select the desired % Backlight. For example, if you select 80%, the brightness of the display will be 80% of the maximum 3. Accept the changes made by pressing the and return to the main screen OR Cancel the changes made by pressing the and go back to the main screen...

  • Page 22: Audible Alarms

    Operation Upgrade Software 1. Install the VentElite USB driver and bootloader driver on your computer (see appendix B for details). Both drivers are located on the CD that was provided with your unit 2. Upload the latest software version to your desktop (the format is filename.srec) 3.

  • Page 23: Mode

    Operation Mode 1. In the Settings screen, select Mode 2. Select the desired mode, Pressure or Volume. A green ring will appear around the button, indicating the mode has been selected 3. Accept the changes made by pressing the and return to the main screen OR Cancel the changes made by pressing the and go back to the main screen Y-Axis Scale...

  • Page 24: Running The Ventelite

    Operation Running the VentElite Once the desired parameters have been entered, the appropriate tubing has been connected, and the subject is in place; hit Start button. The VentElite status will be displayed as “Ramping” as the ventilator starts running. While ramping, the Settings button will be inactive.

  • Page 25: Troubleshooting Guide

    Troubleshooting Guide Unit will not power On Ensure that power supply and cord are securely plugged into unit and outlet. Ensure that outlet is live. Under Pressure Check for leak in tubing. Check for leak in the intubation or tracheotomy. Over Pressure Check for blockage or kink in tubing.

  • Page 26: Appendix B: Using Pressurized And/Or Anesthetic Gas

    Appendix B: Using Pressurized and/or Anesthetic Gases The VentElite was designed to operate utilizing gas sources of atmospheric pressure. When pressurized, constant flow devices are used with the VentElite (such as regulators, flowmeters, and house gas supplies) measures must be taken to ensure no damage is done to the unit. We recommend the use of our connection kit when using a high pressure gas source with the VentElite, or any of our ventilators.

  • Page 27: Appendix D: Error Codes

    Appendix D: Error Codes The VentElite error conditions are categorized into 4 groups: PIP errors, PEEP errors, Volume (Vt) errors, and System errors. Error codes are displayed as a group of five characters (0-9 or A-F), where the second character contains the System status, the third is the Vt status, the fourth is the PEEP status and the fifth is the PIP status.
  • Page 28 Appendix D: Error Codes Error R/Y Error Code (Text) Audible Meaning Group Alarm Type Pressure exceeds average xxxx3 Over Pressure pressure by more than 20% (Increasing average PIP) Pressure exceeds average xxxx4 Over Pressure pressure by more than 10% (Increasing average PIP) but less than 20% Pressure exceeds PIP set point xxxx5 (Over pressure)

  • Page 29: Appendix E: Driver Installation

    Appendix E: Driver Installation Before connecting the VentElite to a computer via USB, the unit should be put into Upgrade Software Mode. To do this, enter the settings screen by pressing the Settings button on the display. Enter the Software Update Mode by pressing the Upgrade Software button, then press Update Application, and the Accept button.
  • Page 30 Appendix E: Driver Installation 3. Select Browse my computer for driver software 4. Click Browse and navigate to the VentElite drivers folder located on the CD supplied with the ventilator. Make sure the “Include Subfolders” box is checked and then click next Publication 5420-009 REV1.0...
  • Page 31 Appendix E: Driver Installation 5. If a warning message regarding the driver publisher is displayed, choose Install this driver software anyway 6. Click Close after the software has been successfully installed 7. Repeat steps 2-6 for the second Flash Update Application listed Publication 5420-009 REV1.0...
  • Page 32 E-mail cma@microdialysis E-mail support@hbiosci.com www.microdialysis.com www.harvardapparatus.com Spain Canada Panlab S.L.U. Harvard Apparatus, Canada C/ Energia, 112 08940 Cornellà (Barcelona), Spain 6010 Vanden Abeele Street Saint Laurent, Quebec, H4S 1R9 Phone +46 8 470 10 00 Phone (514) 335-0792 +46 8 470 10 50...

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