H&O Equipments CryoPen B+ User Manual page 15

This can cause blisters and pain to patients.
Condensation of humidity in the air on the frozen field of the lesion during operation may in some cases create
an ice field on top of the lesion. This 'igloo of ice' will hinder the effective working of the liquid phase of the
cryogen (at -89°C/-128 °F) and should be removed with the applicator tip.
After thawing, the tissue turns reddish and has the aspect of a zone of inflammation due to interstitial bleeding.
The learning curve for utilizing the CryoPen is short. CryoPen provides the possibility
to have full control in the application of freezing power. Start practicing on the regular lesions and treat
the more delicate ones after having acquired some experience.
Duration/Depth of the treatment
Hold the tip of the applicator as close as possible to the lesion. In all literature, the rapid drop of temperature
(thermal shock) is described as a essential criterion. However, always relate to the part of the body where
the operation is applied. In some parts, skin is thinner which requires more caution. A typical freeze on viral
infections may last from 5 to 10 seconds for a small flat wart, and up to 45 seconds for a full thickness plantar
wart. For general purposes most lesions take about 2 to 30 seconds. The duration of the treatment time will
depend on the surface area and the thickness of the tissue being treated. Thickness must be estimated based
on clinical experience. After the first freezing cycle the tissue should be allowed to thaw for about 30 seconds
followed by a second freeze. Note that the tissue will freeze faster than during the first freezing cycle.
This 'freeze-thaw-freeze' technique offers the best opportunity for success. You up visit is recommended after
2 to 4 weeks to confirm that all pathological tissue has disappeared or that a follow-up treatment is necessary.
15