4
Using the Module
Solvent Information
Fluorinated polymers (PTFE, PFA, FEP, FFKM, PVDF)
Fluorinated polymers like PTFE (polytetrafluorethylene), PFA
(perfluoroalkoxy) and FEP (fluorinated ethylene propylene) are inert to
almost all common acids, bases, and solvents. FFKM is perfluorinated rubber,
which is also resistant to most chemicals. As an elastomer, it may swell in
some organic solvents like halogenated hydrocarbons.
TFE/PDD copolymer tubings, which are used in all Agilent degassers except
1322A, are not compatible with fluorinated solvents like Freon, Fluorinert, or
Vertrel. They have limited life time in the presence of Hexafluoroisopropanol
(HFIP). To ensure the longest possible life with HFIP, it is best to dedicate a
particular chamber to this solvent, not to switch solvents, and not to let dry
out the chamber. For optimizing the life of the pressure sensor, do not leave
HFIP in the chamber when the unit is off.
The tubing of the leak sensor is made of PVDF (polyvinylidene fluoride), which
is incompatible to the solvent DMF (dimethyl formamide).
Sapphire, Ruby and Al
O
-based ceramics
2
3
Sapphire, ruby and ceramics based on aluminum oxide Al
O
are inert to
2
3
almost all common acids, bases and solvents. There are no documented
incompatibilities for HPLC applications.
MS Flow Modulator User Manual
39