The "Detector Gas Low" warning (Code 5) on the Biodex ATOMLAB 500 indicates that the grams of argon have dropped more than 5% from the initial factory value. This warning is correctable, but the system does not perform automatic correction. To address this issue, the detector should be serviced.

This answer is automatically generated

Summary of Contents for biodex ATOMLAB 500

Page 1 ATOMLAB 500 DOSE CALIBRATOR OPERATION AND SERVICE MANUAL 086-330 FN: 10-096 Rev G 3/16...
Page 2 Atomlab 500 Dose Calibrator This manual contains operating procedures for the following Biodex product: #086-330 Atomlab 500 Dose Calibrator ATOMLAB 500 DOSE CALIBRATOR...
Page 3: Table Of Contents
- Large Transition During Initialization- Select Detector ............ 34 - Select Detector ......................34 - Select Isotope ....................... 35 - Determining Dial Value Adjustments ................Atomlab 500 Utilities ..........................39 - System Configuration ...................... 40 - Detector Locations ......................41 - Serial Number ....................... 42 - Facility ..........................
Page 4 - Moly Transfer ......................... 116 - Draw Patient Dose From Inventory ................. 117 - Inventory Kit List ......................118 - Tec-Control Paper Chromatography ................120 - Future Dose Calculation ....................122 - Volume Dose Calculation ....................125 ATOMLAB 500 DOSE CALIBRATOR...
Page 5 G. Serial Communications Interface ..................219 H. Conformance To Standards ..................... 227 Determining Dial Values ....................231 Quality Assurance Testing of Atomlab Calibrators ............235 K. Tec-Control Formulas ...................... 243 L. Replacement Parts ......................245 M. Schematics ........................247 Biodex Medical Systems, Inc. © 2016...
Page 6: Definition Of Symbols
“On” Power “OFF” Power Earth (ground) Alternating Current Fuse USB Connector/Cable Waste in Electrical Equipment Date of Manufacture Type B Applied Part CE Mark CE Mark for products with EC Certificate Certified for Safety by ETL Intertek ATOMLAB 500 DOSE CALIBRATOR...
Page 7: Before Proceeding
Atomlab 500 Dose Calibrator both properly and safely. Specific Cautions • Allow only qualified, trained personnel to operate or service the Atomlab 500. • If the equipment is used in a manner other than specified in this operation manual, the protection provided by the equipment may be impaired and results could be compromised.
Page 8 • Sauf lorsque en utilisant le Bouclier de Moly, Bien le Paquebot et le Cincle doivent être utilisés pour tous Atomlab 500 Dose mesures de Calibrator. • Le Bouclier de Moly est utilisé avec le bouclier en métal fourni pour le placement Nécessaire dans la dose détecteur de calibrator.
Page 9 On-site installation and training is optional. The operation manual includes assembly and operating instructions. An applications training webinar is available on the internet at no charge; application questions can be directed to our service department during business hours. Biodex Medical Systems, Inc. © 2016...
Page 10: Product Certifications And Classifications
ICC 60601-2 EMC Standard. NOTE: Circuit diagrams for this product are provided in the Schematics section at the back of this manual. Authorized European Community Representative: Emergo Europe Molenstraat 15 2513 BH, The Hague The Netherlands ATOMLAB 500 DOSE CALIBRATOR...
Page 11: Important Safety Information
For cleaning and maintenance instructions, refer to Table of Contents. CAUTION: Operation for: 100-240 VAC, 50/60 Hz. ATTENTION: Opération pour: 100-240 VAC, 50/60 Hz. WARNING: Only use approved power supplies. AVERTISSEMENT: Utilisez Seulement des alimentations électriques approuvées. Biodex Medical Systems, Inc. © 2016...
Page 12 Ne placez pas le produit dans une position où le bouchon n'est pas facilement accessible. CAUTION: The product is intended to remain in one location during operation. ATTENTION: Le produit est voulu rester dans un emplacement pendant l'opération. ATOMLAB 500 DOSE CALIBRATOR...
Page 13: Unpacking Instructions
If any damage is noted, do not unpack the contents. Notify the carrier immediately so that a claim can be made if necessary, and contact your Biodex Medical Systems Sales Representative. If there is no visible damage, remove the cartons and place them on a table or to the side.
Page 14: Warranty
CONSEQUENTIAL OR INDIRECT DAMAGES INCLUDING LOSS OF USE, SALES, PROFITS OR BUSINESS INTERRUPTION. B. This warranty does not apply if the product, as determined by BIODEX MEDICAL SYSTEMS, INC., is defective due to abuse, misuse, modification or service performed by other than a BIODEX MEDICAL SYSTEMS, INC.
Page 15 2. Check the instruction manual and operations procedure. 3. Check the instruction manual troubleshooting Guide. If you still think you have a service problem, call BIODEX MEDICAL SYSTEMS, INC., Service Department at (800) 224-6339. Keep Yourself And The Phone Next To The Equipment.
Page 16 ATOMLAB 500 DOSE CALIBRATOR...
Page 17: Introduction
Additionally, there are advanced, but easy-to-use programs for Nuclear Pharmacy, radiochemistry and radiochromatography. Figure 1.1. The Atomlab 500 features large, easy to read icons, prompts and values on a touch-screen display. Biodex Medical Systems, Inc. © 2016...
Page 18: Description
The detector has electronics and the calibration built into it (the calibrator is built into the detector.) Therefore, you can connect any Atomlab 500 display to a detector and have a calibrated system. Detector Well Liner Placed within the well is a plastic liner to protect the detector from contamination in the event of the source leaking during measurement.
Page 19: Rear Panel
Institute of Standards & Technology. The Display Unit The Atomlab 500 Dose Calibrator display unit consists of function keys and an LCD display that allows you to make activity measurements. A built-in microprocessor executes commands input via the touch panel and computes activity values from detector data.
Page 20: Display Units
GBq indicated, the activity is 2,360,000,000 becquerels. Routine Isotopes The routine radioisotope (isotope selection) keys for the Atomlab 500 include: Tc-99m, TI-201, I-123, I-131, Cs-137, Co-57, Xe-133, Ga-67, In-111, F-18, Y-90s, and Ba-133. The Co-57, Ba-133 and Cs-137 buttons are primarily used for accuracy and constancy tests.
Page 21: Installation
Choose a location for your dose calibrator which is not frequently used by other personnel — one where the table on which it lies will not be bumped. In general, make sure your work area is clean, dry, and dust free. Biodex Medical Systems, Inc. © 2016...
Page 22: Power Requirements
Temperature: 10 to 30°C Humidity: 0 to 90% rh, non-condensing For optimum performance, the Atomlab 500 Dose Calibrator should be operated in a normal laboratory environment where the temperature and humidity are maintained for normal human comfort and the ambient radiation level is low and constant.
Page 23: Cable Connections
Serial Port (Aux Computer) Figure 2.1. The Atomlab 500 cable connections (on back of unit.) Chamber Display Label Printer Printer Figure 2.2. The Atomlab 500 Display connected to a detector, label printer and printer. Biodex Medical Systems, Inc. © 2016...
Page 24 5. Insert the free end of the detector cable into the mating display port (there are two RJ-12 ports on the detector). 6. If you would like to connect a computer to the Atomlab 500, attach a null modem RS-232 Cable (or USB/RS-232 converter cable) with a DB9 connector to the computer serial port and then attach the opposite end of the cable to the appropriate port on the display.
Page 25: Power Up
Power Up And System Test (See Figure 2.3.) Figure 2.3. The Atomlab 500 System Test screen. Connect the power cable to the back of the display unit and then plug the power supply into a wall socket. Toggle the power switch, located on back of the display, to the “ON” (I) position. The green power on led on the display will light and the system automatically performs a background count and system-test as part of the power-up process.
Page 26: Save The Packing Material
Once the system check is completed, touch <Print> to generate a printout of the system test results and/or touch <Home> to advance to the Atomlab 500 Home screen. Save The Packing Material Now that you have set up your Atomlab dose calibrator, and everything is intact and functioning properly, take a few moments to repack the packing material.
Page 27: Dose Calibrator Operation
(See Figure 3.1 and 3.2.) Figure 3.1. The Atomlab 500 Home screen. Figure 3.2. When a Wipe Test Counter is attached, the Atomlab 500 system displays the Home page icon for both the detector and well counter. Biodex Medical Systems, Inc. © 2016...
Page 28: The Dose Calibrator Program
Easy to read and intuitive to use, the Atomlab 500 touch screen display prompts users to Advance effortlessly and logically though the Dose Calibrator (Chapter 3), Utilities (Chapter 4), Nuclear Pharmacy (Chapter 5), and Dose Calibrator Quality Assurance (Chapter 6) programs.
Page 29: Counting An Isotope
1. Touch the appropriate <Isotope> key. This tells the detector which dial value to use in the calculations. 2. Place the isotope in the detector. The activity level is immediately displayed. 3. Touch <Print Labels> to print out an activity label, or <Home> to return to the System Home screen. Biodex Medical Systems, Inc. © 2016...
Page 30 Figure 3.4 . The Dose Calibrator screen with List 2 Button isotopes displayed. ATOMLAB 500 DOSE CALIBRATOR...
Page 31: Changing The Selected Isotope
The Routine Isotopes List, which displays up to 19 routine isotopes, is accessed by touching <Select Isotope>. Scroll down the Routine Isotope List to access the Custom Isotopes List and full Alphabetical Isotopes List. Biodex Medical Systems, Inc. © 2016...
Page 32: Isotope Response Time
Isotope Response Time The Atomlab 500 normally settles within three seconds as long as the minimum threshold level is exceeded. When you first lower the source into the well, the activity value quickly jumps to the final value. For a few seconds the value may fluctuate, but then the value settles down to a small variation.
Page 33 4. When the countdown is completed, the system always returns to the screen from which <Zero Background> was selected. NOTE: If there has been no change in activity within the detector for more than 100 seconds, the system will quickly zero the background when <Zero Background> is selected. Biodex Medical Systems, Inc. © 2016...
Page 34: Large Transition During Initialization- Select Detector
The <Select Detector> icon allows the user to choose a different detector when more than one detector is connected to the system. The Atomlab 500 can accommodate up to seven dose calibrator detectors (or six dose calibrator detectors and one wipe detector).
Page 35: Select Isotope
3. Touch the desired isotope to highlight your selection. 4. Touch <Enter> to select the desired isotope and return to the Measure screen with the new isotope selected, or touch <Cancel> to return to the Measure screen without making a new selection. Biodex Medical Systems, Inc. © 2016...
Page 36: Determining Dial Value Adjustments
NOTE: Write down the dial value you have determined before exiting this screen as the dial value will not be saved. ATOMLAB 500 DOSE CALIBRATOR...
Page 37 NOTE: The dial value adjustment is not stored when you exit the Dial Value Adjustment screen. You must go to Utilities to change and save a dial value. Biodex Medical Systems, Inc. © 2016...
Page 38 ATOMLAB 500 DOSE CALIBRATOR...
Page 39: Atomlab 500 Utilities
Selecting <Utilities> from the Home screen allows access to the Utilities menu. Touch the appropriate screen icon to choose the desired function. Utilities Menu Options Include: • System Configuration • Dose Calibrator Configuration • System Maintenance Biodex Medical Systems, Inc. © 2016...
Page 40: System Configuration
The System Configuration options allow the user to enter or customize various system-wide Parameters. Any changes made to the configuration settings are permanently saved when exiting the Configuration screen. Touch <System Configuration> on the Utilities menu to access the System Configuration screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 41: Detector Locations
(See Figure 4.3.) Figure 4.3. The detector locations screen. The Atomlab 500 display automatically senses every detector connected and can tell what type it is. Detectors are listed numerically with detector # 1 being the lowest ID number. <Detector Locations> allows the user to specifically label the location of any connected detector.
Page 42: Serial Number
2. Enter your password and touch <Enter>. The Serial Numbers screen is displayed with a listing of all serial numbers recorded for the system. 3. Touch <◄> to return to the System Configuration screen. NOTE: Serial numbers can only be viewed on this screen. You cannot change the serial number. ATOMLAB 500 DOSE CALIBRATOR...
Page 43: Facility
4. Use the <▼> at the top right of the screen to move to each line of the address. You can add the phone number if desired as part of the address. NOTE: There are a maximum of 4 lines to the address. You can enter your phone number as part of the address. Biodex Medical Systems, Inc. © 2016...
Page 44: Date/Time
Touch the desired country to select. Not all countries are listed. Select a country with the same time format you require. 5. Touch <Enter> to return to System Configuration screen with the new time/date, or <Cancel> to exit without updating the date/time entry. ATOMLAB 500 DOSE CALIBRATOR...
Page 45: Activity Units
The system volume can be from 1 (lowest) to 10 (loudest) touch the desired value on the tone scale to set. • Touch <Home> to return to the Home screen. • Touch <Back> to return to the Utilities screen. • Touch <Measure> to return to the <Count> screen. Biodex Medical Systems, Inc. © 2016...
Page 46: Printer Settings
5. Enter the IP address and touch <Done>. The IP address entered should now be displayed next to the network IP button. 6. Touch <OK> to select the displayed IP address and return to the System Configuration screen, or <Cancel> to return to System Configuration screen without changing printer setting. ATOMLAB 500 DOSE CALIBRATOR...
Page 47: Staff Members
Figure 4.8. The Staff Members List screen. The Staff Members List allows a specific staff member to be associated with any Atomlab 500 QA test. Staff are listed in the order entered. New staff may be added to the list and staff members may also be removed.
Page 48: Web Server Settings
1. At the Staff Members List, touch <Print>. The Staff Members List will print to the currently selected printer. Web Server Settings (See Figure 4.9.) NOTE: For JSON programming interface only. Select <Web Server Settings> from the System Configuration screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 49: Dose Calibration Configuration
To access the Dose Calibrator Configuration screen: 1. Select <Utilities> from the Home screen. The Utilities screen is now displayed. 2. Select <Dose Calibrator Configuration> from the Utilities menu. The Dose Calibrator Configuration screen is now displayed. Biodex Medical Systems, Inc. © 2016...
Page 50: Isotope List
Isotope List (See Figures 4.11 and 4.12.) Figure 4.11. The Isotope List screen. Figure 4.12. The Select Current Isotope screen with Routine List displayed. ATOMLAB 500 DOSE CALIBRATOR...
Page 51 This option can be used to select an isotope that is not displayed on the Measure screen List 1 or List 2. A full Alphabetical list of Isotopes, the Routine Isotopes List, and Custom Isotopes with which the Atomlab 500 is designed to work, is provided on the Select Current Isotope screen.
Page 52: Setup Routine Isotopes
6. Touch <Insert> to place the isotope where desired. 7. Touch <Enter> to save the updated Routine Isotope List, or <Cancel> to return to the Setup Routine Isotopes screen without making changes. ATOMLAB 500 DOSE CALIBRATOR...
Page 53 1. From the Isotope List screen, touch <Setup Routine Isotopes>. The Setup Routine Isotopes screen is displayed. 2. Touch <Restore Factory settings> and touch <Yes> to revert to the factory defaults, or <No> to return to the Setup Routine Isotopes screen without making changes. Biodex Medical Systems, Inc. © 2016...
Page 54: Setup Button Isotopes
4. Touch <Enter> to save the updated Isotope Buttons, or <Cancel> to return to the Setup Routine Isotopes screen without making changes. 5. If desired, touch <Restore Factory Settings> and touch <Yes> to revert to the factory defaults, or <No> to return to the Setup Button Isotopes screen without making changes. ATOMLAB 500 DOSE CALIBRATOR...
Page 55: Add Isotope
Press <No> to keep the changes, followed by <Enter> on the Setup Routine Isotope screen. Press <Yes> if you do not want to make the changes and the system returns to the Isotope List screen. Biodex Medical Systems, Inc. © 2016...
Page 56: Remove Isotope
Touch <Yes> to remove the isotope or <Cancel> to not remove the isotope and return to the Isotope List screen. NOTE: Only new isotopes added to the system by the user can be removed. ATOMLAB 500 DOSE CALIBRATOR...
Page 57: Change Dial Value
8. Touch <Change Dial Value> to display the dial setting entry screen and enter the new value. 9. Touch <Enter> to record the new dial value and return to the Change Dial Values screen with the new dial value now highlighted. Biodex Medical Systems, Inc. © 2016...
Page 58: Set Acceptance Variance
NOTE: After restoring factory dial values, scroll the Isotope List and verify that no new dial values are listed. Set Acceptance Variance (See Figure 4.18.) Figure 4.18. The Set Acceptance Variance screen. Set acceptance variance is used to program allowable variances for each of the Individual QA tests. ATOMLAB 500 DOSE CALIBRATOR...
Page 59: Sealed Source Setup
Dose Calibrator Configuration screen. Sealed Sources Setup (See Figures 4.19 - 4.21.) Figure 4.19. The Sealed Source List. Note that Cs-137 is marked as the default (>>) in this example. Biodex Medical Systems, Inc. © 2016...
Page 60 <Enter> to return to the Sealed Source Setup screen. The Calibration Date is now displayed. 5. Touch <Enter Source ID>. The source ID keypad is now displayed. Key in the source ID and touch <Enter> to return to the Sealed Source Setup screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 61 To Print A List Of Sealed Sources: 1. At the Sealed Sources List screen, touch <Print>. The entire Technologist List will print to the currently selected printer. 2. Touch <Back> to return to the Sealed Source List. Biodex Medical Systems, Inc. © 2016...
Page 62 Figure 4.21. A Sealed Source List print out. ATOMLAB 500 DOSE CALIBRATOR...
Page 63: Set Background Counting Time
Adjusting The Background Counting Time: 1. At the Home screen, select <Utilities>. 2. On the Utilities screen, select <Dose Calibrator Configuration>. 3. On the Dose Calibrator Configuration screen, select <Set Background Time>. Figure 4.22. Dose Calibrator Configuration screen. Biodex Medical Systems, Inc. © 2016...
Page 64 20 µCi of Tc-99m, increasing background count time to 100 seconds will improve accuracy. 6. Select <Enter> to return to the Dose Calibration Configuration screen. The background counting time is now changed. Select <Home> to return to the Home screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 65: Label Printing Preferences
These labels feature the radiation warning symbol and the word caution printed in the left corner. The 2 up label can be replaced with a 1 up label (not supplied by Biodex). The small strip label can be used to label syringes, syringe shields, etc. Both the large and small label styles print different information depending on the function from which you are printing.
Page 66: Setup Isotope And Kit List
It is important to input the correct formula selection for the type of kit and strips to be used. Certain kits use one strip, others use two strips. Each strip is cut and the two sections are counted separately. Different formulas are used depending on the kit selected. ATOMLAB 500 DOSE CALIBRATOR...
Page 67 You must select a kit type before you can save the kit. You can select N/A if there is no formula available. NOTE: See Appendix K for a listing of kit types and formulas programed into the system. Biodex Medical Systems, Inc. © 2016...
Page 68 To Print The Setup Inventory Isotopes and Kits List: 1. To print the Setup Inventory Isotopes and Kits list at any time, touch <Print List>. The complete list is printed. Figure 4.27. An Inventory Isotope and Kit Lists printout. ATOMLAB 500 DOSE CALIBRATOR...
Page 69: Low Activity Resolution
To Toggle Between The One- And Two Decimal Settings: 1. At the Dose Calibrator Configuration screen, touch the Volume Decimal Digits value displayed and then select either 1 or 2. 2. Touch anywhere on the screen display to enter your selection. Biodex Medical Systems, Inc. © 2016...
Page 70: System Maintenance
• System Test • Detector Status • Detector Management • Source Detection Threshold • Touch Screen Calibration • Updating The System Firmware To access the System Maintenance screen, from the Dose Calibrator Utilities screen, touch <System Maintenance>. ATOMLAB 500 DOSE CALIBRATOR...
Page 71: Data Management
7. Touch the date segment to change and use <▲> or <▼> to scroll to the date desired. 8. Touch <Enter> to confirm the new date and return to the QA Data Export screen. Biodex Medical Systems, Inc. © 2016...
Page 72 Touch <No> to return to the QA Data Management screen without importing data. 7. At the Import Successfully Completed screen, touch <OK> to return to the Summary View of Stored QA Data screen. Figure 4-30. The summary view of All Stored QA Data. ATOMLAB 500 DOSE CALIBRATOR...
Page 73 Figure 4.31. The QA Data Export screen. Figure 4.32. The QA Data Import screen. Biodex Medical Systems, Inc. © 2016...
Page 74 8. Touch <QA Dataset> to view the dataset options. Choose from “All” datasets, or continue touch- ing <QA Dataset> to scroll through the list of individual datasets. 9. Touch <Delete Now> to delete the selected dataset and return to the summary view of stored QA Data screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 75: Usb System Backup
This function allows the export of all Atomlab files and data to a thumb drive, providing a means of backing-up the system when needed or desired. To Backup The Atomlab 500 QA Data: 1. Insert a thumb drive into one of the USB ports on the back panel of the display.
Page 76: Usb System Restore
They system will prompt you to confirm before proceeding with this function. This function allows the user to restore all Atomlab 500 files from a thumb drive backup. NOTE: Restoring the data will overwrite all current stored data, settings, event log and firmware information.
Page 77: Event Logger
Figure 4.36. The Event Log screen with all events listed for the past 30 days. This shows all events recorded in the dose calibrator for use in determining problems encountered with the system. If needed, this function will be explained by a Biodex Service Representative. Biodex Medical Systems, Inc. © 2016...
Page 78: System Test
• If a printed System Test Report is required, touch <Print> to print the System Test screen following the test. • Touch <Home> to return to the System Home page. • Touch <Back> to return to the System Maintenance screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 79: To Change Id
Touch <Home> to return to the System Home page. NOTE: Each detector connected must have a different ID number. You cannot have two detectors with the same ID. ID numbers available are 2, 4, 6, 8, 10, 12 and 14. Biodex uses I.D. #14 for a wipe detector.
Page 80: Detector Management
2. Enter your password and touch <Enter>. The Detector Management screen is displayed with detector I.D. numbers, detector types, serial numbers and detector locations. The <Remove From Selection List> button toggles with an <Add to Selections List> button on the Detector Management screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 81: Source Detection Threshold
2. Touch <Source Detection Threshold>. The Source Detection Threshold screen is displayed. At this screen you can choose to have the source detection threshold set automatically when a Zero Background is performed, or set the threshold manually. Biodex Medical Systems, Inc. © 2016...
Page 82: Touch Screen Calibration
1. From the Utilities menu, touch <System Maintenance>. The System Maintenance screen is displayed. 2. Touch <Touch Screen Calibration>. The <Enter Password> window is displayed. Enter your password and touch <Enter>. The Calibrating Touch screen message is displayed. ATOMLAB 500 DOSE CALIBRATOR...
Page 83: Updating The System Firmware
Updating The System Firmware Figure 4.42. The Firmware Update Available screen. The Atomlab 500 system is easy to update should new firmware be required. To Update The Atomlab 500 Firmware: 1. At the Home screen or Measure screen, place the new firmware thumb drive into one of the USB ports on the back of the display.
Page 84 3. If you choose to update the firmware now, touch <Yes> to begin the upload. 4. The upload will complete after several seconds, and the system will then automatically reboot. Remove the thumb drive only after the system reboots and begins to initialize background. ATOMLAB 500 DOSE CALIBRATOR...
Page 85: Nuclear Pharmacy
The Enter Isotope into Inventory procedure has a function that includes the Moly Assay procedure when putting Tc-99m into inventory. When entering an isotope other than Tc-99m the Moly Assay selection is not provided. Biodex Medical Systems, Inc. © 2016...
Page 86: Moly Assay (Moly Breakthru)
<Enter>. The Moly Assay Background Counting screen will be displayed with the new background counting time. 5. Make sure there is no source in the detector. Place the empty Moly Shield into the detector and touch <Zero Background>. ATOMLAB 500 DOSE CALIBRATOR...
Page 87 11. Remove the Tc-99m vial or syringe from the Moly Shield and place a vial or syringe into the detector. 12. Touch <Record Reading> to record the Tc-99m activity. The Moly Assay Results screen is now displayed giving the Moly concentration of µCi Mo/mCi Tc-99m. Biodex Medical Systems, Inc. © 2016...
Page 88 13. Touch <Back> to return to the Nuclear Pharmacy screen or <Measure> to advance to the Measure screen. Figure 5.7. The Moly Assay Tc-99m Record Activity screen with Moly Assay activity displayed. Figure 5.8 The Moly Assay Results screen showing activities and Moly concentration. ATOMLAB 500 DOSE CALIBRATOR...
Page 89: Half Life Verification
NOTE: The dose calibrator does not store the Half Life calculation. You can print the results. NOTE: It is up to the user to decide if this variance is acceptable or if there are too many contaminants in the isotope to use it. Figure 5.9. The Nuclear Pharmacy screen. Biodex Medical Systems, Inc. © 2016...
Page 90 6. Select <Set Test Parameters> to display the Half Life Verification parameters. 7. Select either <2> or <3> for the number of readings. If the number is already highlighted, you do not need to select it. ATOMLAB 500 DOSE CALIBRATOR...
Page 91 NOTE: If you select <End Recording>, the Half Life Verification APP will end and use the elapsed time for the calculation. If the counting time is not long enough, it could affect the results. It is recommended to have the count complete the preset time. Biodex Medical Systems, Inc. © 2016...
Page 92 Select <Print> to print your results. If you select <Back>, a message will be displayed that if you proceed your data will be lost. Select <No> not to exit; select <Yes> to exit and lose the test data. ATOMLAB 500 DOSE CALIBRATOR...
Page 93 Figure 5.15. Three Reading Half Life Verification Results. 16. If you desire to start another Half Life Verification, you must select <Set Test Parameters> and review the parameters and then select <Enter>. At this point you can start another test. Biodex Medical Systems, Inc. © 2016...
Page 94 18. After the APP ends you can print the report for the half life verification. Select <Print> and the three reading print reports. NOTE: The system does not store the half-life calculation. You must print the results. ATOMLAB 500 DOSE CALIBRATOR...
Page 96 Half Life = 1.759 hr Variance Formula Half Life Variance = calculated Half Life – isotope Half Life Isotope Half Life Example for F-18: Half Life Variance = 1.76 – 1.83 1.83 Half Life Variance = 3.8% lower ATOMLAB 500 DOSE CALIBRATOR...
Page 97: Enter Isotope Into Inventory
6. Look at the current sample activity reading, displayed in red. This is the current background reading. If it is too high, touch <Zero Background> and then zero the background reading if necessary. Touch <Back> to return to the Enter Kit # Data screen. Biodex Medical Systems, Inc. © 2016...
Page 98 Figure 5.19. The Select Inventory and Isotope Kit screen. Figure 5.20. Enter Kit # and Data screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 99 NOTE: Press <Print Label> if a label is desired. To save, touch <Save Data>. Press <OK> to confirm and return to the Nuclear Pharmacy screen. Figure 5.21. Kit labels without Moly. Biodex Medical Systems, Inc. © 2016...
Page 100: Enter Tc-99M Into Inventory With Moly
6. Press <Yes> to perform the Moly Assay. The Moly Assay reading screen is now displayed. NOTE: If you press <No>, you cannot perform a Moly Assay test. Figure 5.22. The Enter Kit # Data screen for Tc-99m. ATOMLAB 500 DOSE CALIBRATOR...
Page 101 9. Make sure there is no source in the detector. Place the empty Moly Shield into the detector and touch <Zero Background>. 10. Select <Zero Background> to begin a background count lasting up to 100 seconds. Biodex Medical Systems, Inc. © 2016...
Page 102 Touch <Print Label> if a label is desired or <Skip Printing> if you do not want to print a label. After printing or skipping the label, the system returns to the Nuclear Pharmacy screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 103 Figure 5.25. The Moly Assay reading screen counting Tc-99m. Figure 5.26. The Moly Assay reading screen showing the Tc-99m and Moly Assay activity along with the concentration of Moly. Biodex Medical Systems, Inc. © 2016...
Page 104 Figure 5.27. Kit labels with Moly. ATOMLAB 500 DOSE CALIBRATOR...
Page 105: Enter Tc-99M Into Inventory Without Moly
8. When the background time reaches zero, the system returns to the previous screen. 9. The <Record Reading> button should now begin to flash. Place the vial or syringe of Tc-99m into the detector and touch <Record Reading>. NOTE: Touch <Print Label> if a label is desired. Biodex Medical Systems, Inc. © 2016...
Page 106 Touch <Print Label> if a label is desired or <Skip Printing> if you do not want to print a label. After printing or skipping the label, the system returns to the Nuclear Pharmacy screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 108: Kit Preparation
Moly concentration information if there was Moly information in the original kit. 3. Touch Select Inventory Kit>. The Select Inventory Kit screen is displayed. Highlight the kit type desired. If necessary, use <▲> or <▼> to scroll to the appropriate kit type you are making. ATOMLAB 500 DOSE CALIBRATOR...
Page 109 <Back> to return to the Kit # Preparation screen to create a new kit. 12. To draw a patient dose from this kit, select <Draw Patient Dose>. You can now draw a dose from the kit just created as described in the following section. Biodex Medical Systems, Inc. © 2016...
Page 110 Figure 5.33. The Kit # Preparation screen. Figure 5.34. The Kit # Data screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 112: Draw Patient Dose
4. Select <Dose Administration Time> to access the Dose Administration Time screen. This screen displays the required dose activity, the current dose required to be drawn now to administer the desired dose, and the volume to draw for your required dose. ATOMLAB 500 DOSE CALIBRATOR...
Page 113 Figure 5.37. The Dose Administration Time screen for future dose. Figure 5.38. The Draw Patient Dose screen with information displayed. Biodex Medical Systems, Inc. © 2016...
Page 114 Select <Back> to return to the Kit # Data screen (where you can print a new label for the kit). you can now select <Back> to return to the Kit number preparation screen. 12. Select <Back> to return to the Nuclear Pharmacy screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 116: Moly Transfer
The original kit must have a Moly reading in order for later kits or doses to have Moly readings associate with them. ATOMLAB 500 DOSE CALIBRATOR...
Page 117: Draw Patient Dose From Inventory
2. Highlight the sample from which to draw, then touch <Enter> to select the sample. The draw patient dose screen is displayed. 3. Proceed as previously explained for draw patient dose when creating a kit. Biodex Medical Systems, Inc. © 2016...
Page 118: Inventory Kit List
Touch <OK> to confirm deletion, or <Cancel> to cancel the deletion and return to the Inventory Kit List without deleting. 5. Touch <Cancel> to exit the Inventory Kit List and return to Nuclear Pharmacy screen without updating the sample list. ATOMLAB 500 DOSE CALIBRATOR...
Page 119 7. If you exit the inventory sample screen after deleting samples from inventory, the system returns directly to the Nuclear Pharmacy screen with those samples deleted from inventory. Figure 5.43. The Inventory Kit List printout. Biodex Medical Systems, Inc. © 2016...
Page 120: Tec-Control Paper Chromatography
Tec-Control Paper Chromatography (See Figures 5.44 - 5.47). Figure 5.44. The Tec-Control Paper Chromatography screen. Figure 5.45. The Tec-Control Paper Chromatography screen with completed calculations displayed. ATOMLAB 500 DOSE CALIBRATOR...
Page 121 9. Touch <Perform Calculations>. Depending on the kit used, the activity for the strip sections counted are displayed along with the appropriate calculated percentages for: • % free Tc-99m Pertechnetate • % Hydrolyzed Reduced Tc-99m • % Bound Radiopharmaceutical Biodex Medical Systems, Inc. © 2016...
Page 122: Future Dose Calculation
(See Figures 5.46 - 5.47.) Figure 5.46. The Future Dose Calculation screen. The Atomlab 500 allows quick and easy calculation of future doses by entering the dose ordered and the administration time. If they have a dose concentration of the vial they will be drawing from, the program also calculates the volume to draw.
Page 123 7. If there is a printer attached, you can touch <Print Labels> to print the Future Dose labels showing Dose Ordered, activity required and measured activity. NOTE: If drawing additional doses, enter the administration time and Dose Ordered for another dose and the system calculates the requirements for that dose. Biodex Medical Systems, Inc. © 2016...
Page 124 Figure 5.47. A Future Dose Calculated Current Activity label. ATOMLAB 500 DOSE CALIBRATOR...
Page 125: Volume Dose Calculation
You must enter both hours and minutes. Touch <OK> to return to the Volume Dose Calculation screen. NOTE: The current dose “Activity Required” now to administer at a future time is displayed. Biodex Medical Systems, Inc. © 2016...
Page 126 15. Touch <Print Labels> to generate a label if a label printer is connected. NOTE: If drawing additional doses, enter the administration time and dose ordered for another dose and the system calculates the requirements for that dose. Figure 5.49. The Dose Concentration Information screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 127 Figure 5.50. Future dose labels showing Dose Ordered, volume to draw and measured activity. Biodex Medical Systems, Inc. © 2016...
Page 128 ATOMLAB 500 DOSE CALIBRATOR...
Page 129: Dose Calibrator Quality Assurance
• Daily Constancy Test • Expanded Constancy Test • Geometry Test • Accuracy Test • View Constancy Data • View Expanded Constancy Data • View Geometry Data • View Accuracy Data • Linearity Testing Biodex Medical Systems, Inc. © 2016...
Page 130: Daily Constancy Test
The Atomlab 500 allows entry of the sealed sources into inventory and decay-corrects these sources for time. These sources are used for the testing of the dose calibrator chambers.
Page 131 • Touch <Back> to return to the Daily Constancy screen just counted. Touch <Back> again to return to the QA Dose Calibrator screen. • <Save Data> is inactive at this point because the data has already been saved. Biodex Medical Systems, Inc. © 2016...
Page 132: Expanded Constancy Test
Figure 6.3. The Save Daily Constancy screen. Expanded Constancy Test (See Figure 6.4 and 6.5. Figure 6.4. The Expanded Constancy Test screen, also known as “channel check.” ATOMLAB 500 DOSE CALIBRATOR...
Page 133 Each detector must be checked individually. The Atomlab 500 allows entry of the sealed sources into inventory and decay-corrects these sources for time. These sources are used for the testing of the dose calibrator detectors.
Page 134 • Touch <View Data> to view the data on the Expanded Constancy Test data screen. • <Save Data> is inactive because the data has already been saved. • Touch <Back> to return to the Daily Constancy screen just counted. Touch <Back> again to return to the QA Dose Calibrator screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 135: Geometry Test
Atomlab Dose Calibrators have been tested for volume dependence in Beta measurements which are expected to be worst case and the results were 0.13%/ml. (Reference: Accurate Dose Calibrator Activity Measurement of Y-90 Ibritumomab Tiuxetan,” J. A. Siegel Et Al, J Nucl Med, 2004, 45:450-454.) Biodex Medical Systems, Inc. © 2016...
Page 136 Figure 6.6. The Geometry Test screen. Figure 6.7. The Geometry Set Test Parameters screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 137 8. Touch <Enter> when all parameters are set to return to the Geometry Test screen. 9. Touch <Zero Background> to zero the background reading, if necessary. The Background live reading is displayed next to the first volume. Biodex Medical Systems, Inc. © 2016...
Page 138 <View Data> to go to the Geometry Test data screen. 18. If you select <View Data> you can see the Geometry Test just performed, or any Geometry test previously completed. If a printout is desired, touch <Print> to print the Geometry Test Data screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 139: Accuracy Test
Figure 6.9. A complete Save Geometry Test data screen. Accuracy Test (See Figure 6.10 - 6.12.) Figure 6.10. The Accuracy Test screen. Biodex Medical Systems, Inc. © 2016...
Page 140 4. Place the sealed source in the dipper and position it in the dose calibrator detector. When the reading stabilizes, press <Record Reading>. 5. Remove the source from the dose calibrator. Insert the source into the detector again. Press <Record Reading> after the reading has stabilized. ATOMLAB 500 DOSE CALIBRATOR...
Page 141 14. If you select <View Data> you can see the Accuracy Test just performed, or any Accuracy Test previously completed. If a printout is desired, touch <Print> to print the Accuracy Test data screen. Biodex Medical Systems, Inc. © 2016...
Page 142 Staff Member Figure 6.12. A printed Accuracy Test data Report. ATOMLAB 500 DOSE CALIBRATOR...
Page 143: View Constancy Data
View Constancy Data (See Figures 6.13 - 6.15.) Figure 6.13. The Daily Constancy Test data screen. Figure 6.14. The Constancy Activity Plots screen. Biodex Medical Systems, Inc. © 2016...
Page 144 4. If desired, touch <Select Detector> to select and view the constancy tests if multiple detec- tors are connected. 5. If desired, touch <Select Sealed Source> if a different sealed source is desired. 6. Touch <Back> to return to the Daily Constancy Test data screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 146: View Expanded Constancy Data
2. Touch to highlight the data to delete. Touch <Delete Data>. The Delete Data Confirmation screen is displayed. Touch <OK> to delete and return to the Expanded Constancy Test data screen. Touch <Cancel> to return to the Expanded Constancy Test data screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 147 It only prints the plot for the constancy source and the data for that source. Figures 6.17. The Expanded Constancy Test data printout. Biodex Medical Systems, Inc. © 2016...
Page 148: View Geometry Data
2. Use <Earlier Date> or <Later Date> to scroll to the test to delete. 3. Touch <Delete Data>. The delete data confirmation screen is displayed. Touch <OK> to delete and return to the Geometry Test data screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 150: View Accuracy Data
2. Use <Earlier Date> or <Later Date> to scroll to the test to delete. 3. Touch <Delete Data>. The Delete Data Confirmation screen is displayed. Touch <OK> to delete and return to the Accuracy Test data screen, or touch <Cancel> to return to the Accuracy Test data screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 152: Linearity Testing
Compare the readings to the calculated activities. You can change from 30 hours to another time point and perform your normalized calculation from that time point. The Atomlab 500 automated linearity test uses 30 hours as the default method.
Page 153 • Calicheck Test data To Access The Linearity Testing menu: 1. From the QA Dose Calibrator screen touch <Linearity Testing>. The Linearity Testing screen is now displayed. 2. Touch to select the desired function. Biodex Medical Systems, Inc. © 2016...
Page 154: Automated Decay Test
Automated Decay Test (See Figures 6.23 - 6.31) Figure 6.23. The Automated Decay Test screen. Figure 6.24. The Automated Decay Test Set Parameters screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 155 You can set this number between 10 and 50 µCi. 7. Touch <Enter> to return to the Automated Decay Test set reading interval screen. Biodex Medical Systems, Inc. © 2016...
Page 156 Figure 6.25. The Automated Decay Setup Options screen. Figure 6.26. Automated Decay Test Set Intervals screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 157 NOTE: You can pause the test, remove the source from the chamber, and perform a <Zero Background> if desired. It is important to Zero Background at low activity if the room background level changes. Figure 6.27. Automated Decay Test screen. Biodex Medical Systems, Inc. © 2016...
Page 158 NOTE: If the time for the reading has passed, the system will take a reading and record the time once you have resumed the test. It does not skip a reading that was not taken at the correct time. ATOMLAB 500 DOSE CALIBRATOR...
Page 159 Figure 6.29. The Save Automated Decay Test screen. Figure 6.30. The Automated Decay Test Data screen. Biodex Medical Systems, Inc. © 2016...
Page 160: Linearity Automated Decay Test
2. The Automated Linearity Test will end automatically when the activity reading falls below 10 µCi’s. 3. If you choose a normalized reading that occurs after the 10 µCi reading, the system will automatically select the middle reading as the normalized value. ATOMLAB 500 DOSE CALIBRATOR...
Page 161 • Taking measurements every 2 hours would require 48 readings to decay below 10 µCi, which will exceed the maximum number of 24 readings for the Atomlab 500. • To record readings every 2 hours using Tc-99m, you could begin a test, take 24 readings and then start a second linearity test and record a second set of readings.
Page 162 Figure 6.31. An Automated Decay Test Data Report. ATOMLAB 500 DOSE CALIBRATOR...
Page 163: Semi-Automated Manual Decay Test
Semi-Automated Manual Decay Test (See Figures 6.32 - 6.39.) Figure 6.32. The Semi-Automated Decay Test screen. Figure 6.33. The Semi-Automated Decay Test Parameters screen. Biodex Medical Systems, Inc. © 2016...
Page 164 <Zero Background> to perform a Zero Background reading at this point. 9. Place the Tc-99m, or another short half-life isotope, into the dipper and then place the dipper with the source into the detector to perform the linearity test. ATOMLAB 500 DOSE CALIBRATOR...
Page 165 Figure 6.34. The Semi-Automated Decay Setup Options screen. Figure 6.35. The Semi-Automated Decay Test screen using averaging method. Biodex Medical Systems, Inc. © 2016...
Page 166 <Measure> to return to standard DOSE CALIBRATOR OPERATION. NOTE: When in the manual portion of the test you can press <Measure> to go to the Measure screen to use the system as a Dose Calibrator. ATOMLAB 500 DOSE CALIBRATOR...
Page 167 NOTE: You can also select the normalized reading while the Semi-Automated Decay Test is underway. If you have not selected a normalized reading before selecting <End Test>, the system automatically displays the Select Normalized Reading screen from which you can select which reading to use as normalized. Biodex Medical Systems, Inc. © 2016...
Page 168 Figure 6.38. The Semi-Automated Decay Test data screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 169 Figure 6.39. The Semi-Automated Decay Test Averaging Method Data printout. Biodex Medical Systems, Inc. © 2016...
Page 170: Manual Decay Test
Manual Decay Test (See Figures 6.40 - 6.44.) Figure 6.40. The Manual Decay Test screen. Figure 6.41. The Manual Decay Test View Data screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 171 5. Touch <Enter> to return to the Manual Decay Test screen with the new variance calculation method selected, or <Cancel> to return to the Manual Decay Test screen without selecting a new calculation method. Biodex Medical Systems, Inc. © 2016...
Page 172 Measure screen. Touch <Return to Manual Decay Test> to go back to the manual decay test. 6. Touch <End Test> to end the test and advance to the Normalized Reading screen. Figure 6.43. The Manual Decay Test screen with Test Ended message and data displayed ATOMLAB 500 DOSE CALIBRATOR...
Page 173 <End Test>, the system automatically displays the Select Normalized Reading screen from which you can select which reading to use as normalized. Figure 6.44. The Decay Test data - Manual printout. Biodex Medical Systems, Inc. © 2016...
Page 174: Decay Test Data
Decay Test Data (See Figures 6.45 - 6.46.) Figure 6.45. The Decay Test data screen. Figure 6.46. The Manual Decay Test screen with Linearity Decay Plot. ATOMLAB 500 DOSE CALIBRATOR...
Page 175 5. Touch <Back> to return to the decay Test data screen. 6. Touch <Earlier Date> and <Later Date> to plot the other linearity tests stored in memory. 7. Touch <Print> to print the linearity plot display. Biodex Medical Systems, Inc. © 2016...
Page 176: Lineator Initial Test
The first time the Lineator is used with this dose calibrator, initial factors for the Lineator function must be set and the Atomlab 500 must be calibrated for the specific Lineator package using the initial procedure described below. The Atomlab 500 will store the initial factors and print them in the initial factor column of the results table.
Page 177 11. Touch <Save Data> to save the data. • Touch <Back> twice to return to the Linearity Testing screen. • Touch <Measure> to advance to the Measure screen. • Touch <View Data> to view the linearity tests stored in the system. Biodex Medical Systems, Inc. © 2016...
Page 178: Lineator Test
55 mCi you must select this range. • Touch <Zero Background> to zero the background reading if necessary. NOTE: The starting activity used for the Linearity Test should be a similar activity to the Initial Linearity Test. ATOMLAB 500 DOSE CALIBRATOR...
Page 179 • Touch <View Data> to view the linearity tests stored in the system. NOTE: The Lineator Test must be performed in less than six minutes or the test must be redone because of decay. See the Lineator instructions. Figure 6.49. The Save Lineator Test data screen. Biodex Medical Systems, Inc. © 2016...
Page 180: View Lineator Data
3. Touch <Delete Data> to delete the test shown on the screen. The Delete Data Confirmation screen is displayed. Touch <OK> to delete and return to the Lineator Test data screen. 4. Touch <Cancel> to return to the Lineator Test data screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 182: Calicheck Initial Test
The first time the Calicheck is used with Atomlab 500, calibrator factors for the Calicheck function must be set and the Atomlab 500 must be calibrated for the specific Calicheck package using the initial procedure described below. The Atomlab 500 will store the initial factors and print them in the factor column of the results table.
Page 183 • Touch <Back> twice to return to the Linearity Testing screen. • Touch <Measure> to advance to the Measure screen. • Touch <View Data> to view the Calicheck linearity tests stored in the system. • Touch <Print> to print the initial Calicheck Test data. Biodex Medical Systems, Inc. © 2016...
Page 184 Figure 6.53. A Save Calicheck Initial Data printout. ATOMLAB 500 DOSE CALIBRATOR...
Page 185: Calicheck Test
4. Once the reading has stabilized, touch <Record Reading>. The reading for the Black Tube only is recorded and the line for the Black and Red Tube is now displayed as a live reading. Biodex Medical Systems, Inc. © 2016...
Page 186 • Touch <Measure> to advance to the Measure screen. • Touch <View Data> to view the linearity tests stored in the system. • Touch <Print> to print the Calicheck linearity test report shown on the screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 188: Calicheck Test Data
3. Touch <Delete Data> to delete the test shown on the screen. The Delete Data Confirmation screen is displayed. Touch <OK> to delete and return to the Calicheck Test data screen. 4. Touch <Cancel> to return to the Calicheck Test Data screen. ATOMLAB 500 DOSE CALIBRATOR...
Page 189: Glossary
Decay Chart A chart projecting how the activity of a source will decay over a period of time at specified time intervals. Detector Unit An Atomlab component housing the ionization chamber detector and the electrometer. Biodex Medical Systems, Inc. © 2016...
Page 190 A sleeve shield package to perform linearity tests on dose calibrators. Moly Breakthrough Shield Used in the Moly Breakthrough Test to shield the radiation of the Tc-99m in an eluent so that the activity of the Mo-99 can be measured. ATOMLAB 500 DOSE CALIBRATOR...
Page 191 Comparison of the calculated and actual activity values constitutes the test of linearity. Traceability Refers to using sources for calibrating a dose calibrator whose activities can be traced to the National Institute of Standards & Technology. Biodex Medical Systems, Inc. © 2016...
Page 192 ATOMLAB 500 DOSE CALIBRATOR...
Page 193: Troubleshooting Procedures
Should you encounter any of the problems discussed in the following sections, immediately perform the accompanying steps to ascertain whether your dose calibrator requires servicing. If you conclude that it does, contact the Biodex Customer Service Department at 1-800-224-6339 for further instructions.
Page 194 If the display continues to fluctuate, and you have verified it is not because of a high calibration value, consult Biodex customer service department. Display Fluctuations For High Calibration Values For some isotopes which require a high calibration value, you may observe fluctuations of ±0.5 µCi or more.
Page 195: Display Diagnostics For 400/500 Series
Atomlab Display Diagnostics For 400/500 Series Overview The nine button black & white Atomlab 400 and color touch screen Atomlab 500 for the new generation of Atomlab products have built-in boot-up self-diagnostics, along with real-time monitoring of the detector statuses. The detectors themselves have real-time self tests, the results of which are reported back to the display approximately once per second.
Page 196 Warnings are errors flagged by the self tests, but not considered permanent or serious enough to not use the reported activity measurements. Failures (FAIL) are considered serious enough to not use the detector for any activity measurements. The detector will automatically be taken offline by the system, no longer selectable. ATOMLAB 500 DOSE CALIBRATOR...
Page 197 This error code should be only temporary, for the time a very high reading is being measured. If this occurs without an explainable cause, the detector may be faulty and should be serviced. Biodex Medical Systems, Inc. © 2016...
Page 198 ATOMLAB 500 DOSE CALIBRATOR...
Page 199: Specifications
APPENDIX C: Atomlab 500 Dose Calibrator Specifications Overview This Appendix provides the physical and operating specifications of your Atomlab 500 Dose Calibrator. Measurement Range For Tc-99m, 0.01 µCi to 100 curies, auto-ranging or 25 curies of F-18. Display Ranges Units are user selectable: 00.00-1999...
Page 200 The unit displays readings in µCi, mCi, Ci, MBq or GBq. dials can be reset for new calibration values. The Mo-99 key is calibrated for Mo-99 assay in a shielded vial of Tc-99m. The Atomlab 500 provides a 30-second countdown. Alphabetical List 24 Routine isotopes...
Page 201 Temperature: 10 to 30°C Humidity: 0 to 90% rh, non-condensing For optimum performance, the Atomlab 500 should be operated in a normal laboratory environment where the temperature and humidity are maintained for normal human comfort and the ambient radiation level is low and constant.
Page 202 Electrical Equipment, Laboratory Use; Part 1, General Requirements for Safety conforms to UL 60601-1, CAN/CSA C22.2 No: 601-1-M90, IEC 60601-1, IEC 60601-1-4 and IEC 60601-1-2. Authorized European Community Representative: Emergo Europe Molenstraat 15 2513 BH, The Hague The Netherlands ATOMLAB 500 DOSE CALIBRATOR...
Page 203: Decay Calculations
8. Elapsed t = 53 min x 1 hr = 0.8833 hr 60 min A = 43 mCi x 2 (-0.8833/6.007) A = 43 mCi x 2 (-0.147045) A = 43 mCi x 0.903 A = 38.83 mCi Biodex Medical Systems, Inc. © 2016...
Page 204 8. Elapsed t = 53 min x 1 hr = 0.8833 hr 60 min 9. Replace equation with following: A = A A = 43 mCi / 2 (0.8833/6.007) A = 43 mCi / 2 (0.1470451) A = 43 mCi / 1.1072992 A = 38.83 mCi ATOMLAB 500 DOSE CALIBRATOR...
Page 205 (5) = 0.03125. 6. From the Decay Factor Chart, the .41 row and the .000 column, (.410) = .75262. 7. A (N) x X (R) = 43 mCi x (0.03125) x (.75262) = 1.01 mCi. Biodex Medical Systems, Inc. © 2016...
Page 206 ATOMLAB 500 DOSE CALIBRATOR...
Page 208 ATOMLAB 500 DOSE CALIBRATOR...
Page 210 R from 0.001 to 0.999. For the above example (5) = 0.03125 (0.410) = 0.75262 = X A = [X (N) x X (R)] A = [0.03125 x 0.75262] 43 mCi = 1.01 mCi ATOMLAB 500 DOSE CALIBRATOR...
Page 212 ATOMLAB 500 DOSE CALIBRATOR...
Page 214 ATOMLAB 500 DOSE CALIBRATOR...
Page 216 Dial Settings For Y-90 The typical Atomlab 500 Dose Calibrator dial setting for Y-90 activity in a 10 cc plastic syringe is 350. This value can be used as a starting point for initial measurements. However, it is recommended that the dial setting used for clinical measurements be determined from the first dose of Zevalin received from the radiopharmacy, as outlined below.
Page 217: Calibration And Traceability
Calibration then takes place with the Co-60 working standard. The calibration value is stored in a special memory chip on the detector circuit board. Calibration is then verified by measuring the activity of all the working standards, including Co-60, Cs-137, Ba-133, and Co-57. Biodex Medical Systems, Inc. © 2016...
Page 218 ATOMLAB 500 DOSE CALIBRATOR...
Page 219: Serial Communications Interface
Appendix G: Atomlab 500 And 500Plus Serial Communications Interface The Atomlab 500 has the ability to be controlled and monitored, with limitations, via the DB-9 RS-232 serial port. Connection Details: Cable: RS-232 female/female null modem, for connection to a standard PC COM Port Port Settings: 19.2 KBAUD, no parity, 1 stop...
Page 220 (sections 1 and 2, or 3 and 4) or 4 readings (sections 1 to 4) being reported. Following is an example of what is returned: Chromatography Total Records: 1 Chamber: 4633919 Date 12/16/2015 9:50 AM Isotope: Tc-99m Kit Number: Kit Name: Exametazime Section Count: 2 Section1: 320. uCi Section2: 323. uCi ATOMLAB 500 DOSE CALIBRATOR...
Page 221 If there are multiple detectors connected, an additional field is added - the detector number. Here is an example of the returned data for an Atomlab 500Plus: 8 359.4 260.2 21.3 7.4 1 14 1188.0 1188.0 52 2 Biodex Medical Systems, Inc. © 2016...
Page 222 Sets the screen password override (1=Override, 0=entry required). If no parameter is given, the current state of the password override is displayed. QADATA Displays a summary of stored QA Data Records. For each QA data type, the allocated space and used space is shown. ATOMLAB 500 DOSE CALIBRATOR...
Page 223 0 Records For the Wipe Test Data, a line will be added immediately after the location line for the Location Type: Type,”Location Type” where ”Location Type” can be Restricted, Unrestricted, Sealed Source, Package Biodex Medical Systems, Inc. © 2016...
Page 224 <Measure> (1=Set On, 0=Turn OFF). If no parameter is given, a detailed state of the current connected detectors is displayed. Displays the Atomlab Display Unit's firmware versions as follows: UDM Vers: 1.22 10/12/2010 Windows CE 6.0 Based System ATOMLAB 500 DOSE CALIBRATOR...
Page 225 Au-198 Sr-87m Au-199 Y-88 TI-201 ---------- Hg-203 Sr-89 Pb-203 Zr/Y-89m Bi-213 Y-90s Y-90v Nb-95 Ra-223 Mo-99 Ac-225 Tc-99m Rt-211 Cd-109 Bi-212/TI-208 In-111 PB-212 In-113m Sn-117m I-122 P-32s (syringe) I-123 Sm-153v (vial) Sm-153s (syringe) 03/18/16 Biodex Medical Systems, Inc. © 2016...
Page 226 ATOMLAB 500 DOSE CALIBRATOR...
Page 227: Conformance To Standards
EN 60601-1-2 when used with the AL 500. Cable description Part no. Cable length Power Input Wall Pack Biodex # C13116 NEMA Cord Set Biodex # C11789 10ft Table 1.2. AL 500 cables. Biodex Medical Systems, Inc. © 2016...
Page 228: Declaration Of Conformity
Declaration Of Conformity Emissions Immunity ATOMLAB 500 DOSE CALIBRATOR...
Page 230 Recommended Separation Distances ATOMLAB 500 DOSE CALIBRATOR...
Page 232 NIST ampoule configuration noted above. All Atomlab Dose Calibrators are calibrated with NIST traceable Co-60, Ba-133, Co-57, and Cs-137 sources. Each dose calibrator is certified to measure the correct activity of the calibration sources to within the specified accuracy. ATOMLAB 500 DOSE CALIBRATOR...
Page 233 Co-60 isotope key. Remember to decay correct the source’s activity for time elapsed since source activity calibration. Biodex Medical Systems, Inc. © 2016...
Page 234 The dial value should only be determined with a calibrated isotope source of known accuracy. Biodex supplies dial values for many isotopes. Many of these dial values are calculated using a Monte Carlo simulation corrected by actual measurements. If a source is available which has calibrated accuracy better than the uncertainty listed in the table in Appendix E, then this source can be used to modify the dial value for an existing isotope.
Page 235: Quality Assurance Testing Of Atomlab Calibrators
1 Press the Zero Background (Bkgnd) activity is less than 200 µCi. investigate potential sources of button. When the display zeroes, error (patients in the area, exposed *Manufactured by Sun Nuclear Corporation, Melbourne, FL; distributed by Biodex Medical Systems. Biodex Medical Systems, Inc. © 2016...
Page 236 “CDV”, determined by the USER with when the isotope has a significant the following procedure. portion of low energy photons in its emission spectrum. where PSA = Plastic Syringe Activity. ATOMLAB 500 DOSE CALIBRATOR...
Page 237 NOTE: You can perform the Sleeve Test procedure first and immediately where T = 6.007 h. Record the val- The Atomlab 500 automated linear- perform a traditional Linearity test. This ues. See linearity form, Figure 1. ity test uses 30 hours as the default...
Page 238 ______ ______ ______ ______ ______ ______ ______ ______ ______ ______ ______ ______ ______ ______ ______ ______ ______ Avg: ______ Accept if 0.95 < Avg / M <1.05 Figure 1. Sample dose calibrator linearity data collection form. ATOMLAB 500 DOSE CALIBRATOR...
Page 239 2. See “Accurate Dose Calibrator Activity Mea- for a 10 ml glass vial, draw 1.0 ml of surement of Y-90 Ibritumomab Tiuxetan,” J. A. Siegel et al, J Nucl Med, 2004, 45:450-454. Tc-99m solution (between 1 and 10 January, 2016 Biodex Medical Systems, Inc. © 2016...
Page 240 January, 2016 ATOMLAB 500 DOSE CALIBRATOR...
Page 242 (DV). The user If repair or replacement is required, follows: can adjust the DV for a particular need. contact Biodex Medical Systems for Remove the plastic dipper and liner Each isotope button should be checked instructions periodically to verify it is set to the from the well chamber.
Page 243: Tec-Control Formulas
Diphoshonate (DSMA) (HMDP) (Glucoheptonate) ) (Pyrophosphate APPENDIX K: Tec-Control Formulas Biodex Medical Systems, Inc. © 2016...
Page 244 (NET CTS SECTION 5) + (NET CTS SECTION 6) % LIPOPHILIC EXAMETAZINE COMPLEX (NET CTS SECTION 1) (NET CTS SECTION 1) X 100 (NET CTS SECTION 1)+ (NET CTS SECTION 3) + (NET CTS SECTION 2) (NET CTS SECTION 4) ATOMLAB 500 DOSE CALIBRATOR...
Page 245: Replacement Parts
APPENDIX L: Atomlab 500 Dose Calibrator Replacement Parts Atomlab 500 Dose Calibrator Replacement Parts C13116 POWER SUPPLY C11789 CORD SET C10547 THREE LOBE KNOB 083-330-E102 UNIVERSAL MEMBRANE SWITCH C13020 ON/OFF SWITCH 950-400-E803 SINGLE BOARD COMPUTER 950-385-E850 PCB, PC-104 DISPLAY...
Page 246 ATOMLAB 500 DOSE CALIBRATOR...
Page 248 ATOMLAB 500 DOSE CALIBRATOR...

biodex ATOMLAB 500 Operation And Service Manual

1 Introduction

2 Installation

3 Dose Calibrator Operation

4 Atomlab 500 Utilities

5 Nuclear Pharmacy

6 Dose Calibrator Quality Assurance

7 Glossary

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