PRESONUS StudioLive 16.0.2 Owner's Manual page 12

2.1 Level Setting Procedure
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13. Press the Select button on Channel 1 and raise the Channel 1
fader until it reaches "U" (unity gain).
14. Bring up the Main fader until you can comfortably listen to
your microphone through your speakers.
15. With Channel 1 selected, you can use the Fat
Channel to add dynamics processing and EQ.