Emerson Rosemount OCX8800 Instruction Manual page 285

Instruction Manual
IM-106-880C, OI
EPIDEMIOLOGY
At this time there are no known published reports demonstrating negative health outcomes of
workers exposed to refractory ceramic fiber (RCF). Epidemiologic investigations of RCF
production workers are ongoing.
1. There is no evidence of any fibrotic lung disease (interstitial fibrosis) whatsoever on x-ray.
2. There is no evidence of any lung disease among those employees exposed to RCF that had never
smoked.
3. A statistical "trend" was observed in the exposed population between the duration of exposure to RCF
and a decrease in some measures of pulmonary function. These observations are clinically
insignificant. In other words, if these observations were made on an individual employee, the results
would be interpreted as being within the normal range.
4. Pleural plaques (thickening along the chest wall) have been observed in a small number of employees
who had a long duration of employment. There are several occupational and non-occupational causes
for pleural plaque. It should be noted that plaques are not "pre-cancer" nor are they associated with
any measurable effect on lung function.
TOXICOLOGY
A number of studies on the health effects of inhalation exposure of rats and hamsters are
available. Rats were exposed to RCF in a series of life-time nose-only inhalation studies. The
animals were exposed to 30, 16, 9, and 3 mg/m3, which corresponds with approximately 200,
150, 75, and 25 fibers/cc.
Animals exposed to 30 and 16 mg/m3 were observed to have developed a pleural and
parenchymal fibroses; animals exposed to 9 mg/m3 had developed a mild parenchymal fibrosis;
animals exposed to the lowest dose were found to have the response typically observed any
time a material is inhaled into the deep lung. While a statistically significant increase in lung
tumors was observed following exposure to the highest dose, there was no excess lung cancers
at the other doses. Two rats exposed to 30 mg/m3 and one rat exposed to 9 mg/m3 developed
masotheliomas.
The International Agency for Research on Cancer (IARC) reviewed the carcinogenicity data on
man-made vitreous fibers (including ceramic fiber, glasswool, rockwool, and slagwool) in 1987.
IARC classified ceramic fiber, fibrous glasswool and mineral wool (rockwool and slagwool) as
possible human carcinogens (Group 2B).
EMERGENCY FIRST AID PROCEDURES
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• SKIN CONTACT - Do not rub or scratch exposed skin. Wash area of contact thoroughly with soap
and water. Using a skin cream or lotion after washing may be helpful. Get medical attention if
irritation persists.
Safety Data Sheet for Ceramic Fiber
Products
EYE CONTACT - Flush eyes immediately with large amounts of water for approximately 15
minutes. Eye lids should be held away from the eyeball to insure thorough rinsing. Do not
rub eyes. Get medical attention if irritation persists.
INHALATION - Remove person from source of exposure and move to fresh air. Some
people may be sensitive to fiber induced irritation of the respiratory tract. If symptoms
such as shortness of breath, coughing, wheezing or chest pain develop, seek medical
attention. If person experiences continued breathing difficulties, administer oxygen until
medical assistance can be rendered.
INGESTION - Do not induce vomiting. Get medical attention if irritation persists.
Safety Data
April 2017
25
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