Waters Alliance iS HPLC Manuals

Manuals and User Guides for Waters Alliance iS HPLC. We have 1 Waters Alliance iS HPLC manual available for free PDF download: User Manual

Waters Alliance iS HPLC User Manual (228 pages)

Brand: Waters | Category: Laboratory Equipment | Size: 7 MB

Table of Contents
2
General Information
9
Copyright Notice
9
About Alliance Is Documentation
9
Searching for Information
9
Trademarks
10
Safety Considerations
10
Safety Hazard Symbol Notice
10
FCC Radiation Emissions Notice
10
Electrical Power Safety Notice
10
Equipment Misuse Notice
11
Safety Advisories
11
Operating the Device
11
Applicable Symbols
11
Audience and Purpose
12
Intended Use of the Alliance Is HPLC System
13
Calibrating
13
Quality Control
13
EMC Considerations
13
Canada Spectrum Management Emissions Notice
13
ISM Classification: ISM Group 1 Class B
13
Additional Resources
14
Contacting Waters
15
Customer Comments
15
Safety Advisories
17
Warning Symbols
17
Specific Warnings
18
Notices
18
Bottles Prohibited Symbol
18
Required Protection
19
Warnings that Apply to All Waters Instruments and Devices
19
Warnings that Address the Replacement of Fuses
23
Electrical Symbols
25
Handling Symbols
26
System Overview
28
Features of the System
28
Flow-Through-Needle Injector
29
System Components
29
Detector Features
30
Detector Optics
31
Operational Modes
35
Spectrum Scanning
38
Pump Features
39
Sample Manager Features
40
Injection System
42
Column Heater/Cooler Features
46
Column Configuration
46
Touchscreen Features
47
Empower Features
53
Auto Additions
54
Selecting Auto-Dilution
54
Installation and Configuration
55
Setting up the System
55
External Connections
55
Network Connections
56
Power Connections
56
Making Solvent Bottle Connections
57
Making Waste Connections
58
Installing the Column
58
Powering-On the System
60
Powering-Off the System
60
Opening the Console from Empower Software
61
Priming the System
63
Priming the Seal-Wash System
64
Required Tools and Materials
65
Priming the Pump
66
Priming the Sample Manager
67
Choosing Extension Loops
68
Installing and Replacing Extension Loops
69
Installing an Extension Loop in a Single-Valve System
70
Installing an Extension Loop in a Two-Valve System
71
Modifying Needle and Extension Loop Configuration Parameters
73
Choosing a Draw Rate for the Sample Syringe
73
Choosing the Needle-Placement Setting
74
Recovering Maximum Sample from Vials
75
Creating a New Plate Type
75
Creating a New Plate Type Using an Existing Plate Type as a Template
76
Loop-Offline Option
76
Determining When to Take the Needle and Extension Loop Offline
77
Choosing the Loop-Offline Option
78
Method Management
79
Measuring Dwell Volume
79
Transferring Methods
79
Daily Routine Analysis
80
Starting the Hardware and Software
80
Setting up Solvents
81
Installing the Column
83
Equilibrating the Alliance Is System
83
Preparing and Loading Samples
86
Checking System Status and Health
88
Data Acquisition Checks
89
Monitoring from the Touchscreen
89
Monitoring from the Empower Control Panel
90
Monitoring from the Alliance Is System Console
90
Acquiring Data
91
Reviewing the Results
91
Printing the Report
91
Putting the Alliance Is System to Sleep
91
Preparing to Shut down the Alliance Is System
92
Performance Optimization
94
General Guidelines
94
Carryover
95
Preventing Leaks
96
Installation Recommendations for Fittings
96
Required Tools and Materials
101
Setting up a Method
103
Sample Chamber Considerations
104
Observing Vial and Plate Recommendations
104
Cycle Time between Injections
105
Reproducibility
105
Maximizing LC Column Lifetime
105
Preventive Maintenance
106
Maintenance
106
Maintenance Safety Guidelines
106
View Module Information
106
Safety and Handling
107
Spare Parts
107
Configuring Maintenance Warnings
107
Cleaning the Exterior of the Equipment
107
Pump Maintenance
108
Recommended Maintenance Schedule for the Pump
108
Servicing the Air Filter in the Door
109
Replacing the Leak Sensor
110
Replacing the Mixer
111
Replacing the Vent Valve Cartridge
112
Replacing the Optional Solvent Selection Valve Cartridge
114
Replacing the In-Line Filter Cartridge on the Primary Check Valve
117
Replacing the Check Valve Filter
123
Replacing the Accumulator Check Valve
124
Replacing the Accumulator Check Valve
127
Required Tools and Materials
127
Replacing the Accumulator Check Valve
129
Replacing the Accumulator Check Valve - Video
131
Replacing the Pump Plungers and Seals
133
Replacing the Primary Pump Head and Accumulator Pump Head Plunger and Seals
134
Required Materials
135
Replacing the Solvent Bottle Filters
156
Autosampler Maintenance
156
Recommended Autosampler Routine Maintenance Schedule
156
Washing the Needle's Exterior
157
Calibrating the Needle Z Axis
158
Replacing the Needle
159
Replacing the Needle Seal and Return Line > Not Return Line
169
Replacing the Inject Valve
182
Replacing the Sample Syringe
182
Cleaning the Injection Port
182
Detector Maintenance
183
Replacing the Detector's Leak Sensor
183
Replacing the Flow Cell
185
Replacing the Lamp
188
Column Heater Maintenance
191
Recommended Maintenance Schedule for the Column Heater
191
Replacing the Column
192
Servicing the Air Filter
196
Troubleshooting
197
Symptoms
197
Resolving Environmental Problems
197
Resolving Solvent Issues
198
Resolving Sample Issues
198
Resolving Quaternary Pump Problems
198
Resolving Pressure Issues
198
Resolving Leak Issues
198
Responding to a Leak Sensor Alarm
200
Diagnostic Tests
202
Running the System Leak Test
203
Running the Needle Seal Readiness Test
204
System Upgrade
205
Empower Updates
205
Empower ICS Updates
205
Kiosk/Console Updates
205
Firmware Updates
205
System Release Notes
206
Disposal Protocols
207
Description of Constituent Materials
207
Disposal of System Components
207
Solvent Considerations
208
Preventing Contamination
208
Clean Solvents
208
Solvent Quality
208
Solvent Preparation
208
Water
209
Solvent Recommendations
209
General Solvent Guidelines
209
Cleaning Agents
211
Wash Solvent Guidelines
212
Solvents to Avoid
213
Material Limitations for Strong Acids and Bases
214
System Solvent Recommendations
214
Integrated Fluidics Module Solvent Recommendations
215
Detector Solvent Recommendation
216
Common Solvent Properties
216
Solvent Miscibility
218
Using Miscibility Numbers (M-Numbers)
219
Solvent Stabilizers
220
Solvent Viscosity
220
Wavelength Selection
220
Ultraviolet Cutoffs for Common Solvents
220
Mixed Mobile Phases
221
Mobile Phase Absorbance
222
Specifications
225
System Specifications
225
Instrument Control Specifications
226
Environmental Specifications
226
Electrical Specifications
227
Physical Specifications
227
Center of Gravity
227
Wetted Materials of Construction
227
Performance Specifications
228

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Waters Alliance iS HPLC Manuals

Waters Alliance iS HPLC User Manual (228 pages)

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