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Summary of Contents for Alpha MED64 MED-A64HE1
- Page 1 A low‐noise multi‐electrode array system for in vitro electrophysiology Product Manual MED64 Head Amplifier 64-CHANNEL HEAD AMPLIFIER P/N: MED-A64HE1...
- Page 2 © 2011 Alpha MED Scientific Inc. All rights reserved Version: 1.10; September 1, 2011 Alpha MED Scientific Inc.
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Page 3: Table Of Contents
Table of Contents Safety Precautions MED64 Head Amplifier Components and Functions MED64 Head Amplifier Set-Up Connecting the MED64 Main Amplifier to other Components 6 Signal Acquisition with the MED64 system Amplifier Input-Impedance Requirements for avoiding Signal Attenuation Stimulation Using Planar Microelectrodes Stimulus Artifacts and Biphasic Stimulation Stimulus Current to be Applied to the Electrodes 10 Warranty... -
Page 4: Safety Precautions
Safety Precautions Before using this unit please read these operating instructions carefully. Take special care to follow the warnings indicated on the unit itself as well as the safety suggestions listed below. Keep these precautions at hand for future reference. Placement - Avoid placing the unit in areas of: •... -
Page 5: Environmental Conditions
Service - Never attempt to repair, disassemble or modify the unit if there seems to be a problem. A serious electric shock could result if you ignore this precautionary measure. - If a problem occurs during operation (smoke is detected, etc.) contact your dealer immediately. - Disconnect the power supply if the unit will not be used for a long time. -
Page 6: Med64 Head Amplifier Components And Functions
MED64 Head Amplifier Components and Functions The MED64 Head Amplifier (64-CHANNEL HEAD AMPLIFIER, MED-A64HE1) is the head amplifier for the MED64 system. Filed potentials (extracellular signals) are acquired from the acute or cultured biological preparations placed onto the 64 planar microelectrodes in the MED probe. The acquired raw signals are amplified by x10 with the MED64 Head Amplifier, then sent to the MED64 Main Amplifier (64-CHANNEL MAIN AMPLIFIER, MED- A64MD1), where input signals are amplified further and digitized. - Page 7 (2) OUTPUT Signal output. Connects to the [INPUT] terminal on the 64-CHANNEL MAIN AMPLIFIER (MED-A64MD1). (3) F1 STIMULUS INPUT Input for F1 stimulator. Connects to the [F1 STIMULUS OUTPUT] on the 64-CHANNEL MAIN AMPLIFIER (MED- A64MD1). (4) F2 STIMULUS INPUT Input for F2 stimulator.
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Page 8: Med64 Head Amplifier Set-Up
MED64 Head Amplifier Set-Up The MED64 system has several technical advantages due to the low-impedance platinum-black microelectrodes on the MED probe (typically 10 kΩ at 1kHz for 50 m electrodes). These include: The system is more resistant to exogenous noise (e.g. hum noise). Very low Johnson noise (baseline noise) as low as a few microvolts can be achieved. -
Page 9: Signal Acquisition With The Med64 System
Signal Acquisition with the MED64 system The MED probe has 64 recording electrodes and 4 reference electrodes. The difference between potentials at the recording electrodes and the reference electrodes are measured with the MED64 system. Fig.1 shows a schematic diagram of the circuit between the recording and reference electrodes with the MED64 system. Reference electrodes Fig.1. -
Page 10: Stimulation Using Planar Microelectrodes
Stimulation Using Planar Microelectrodes The MED64 Head Amplifier has a built-in 2 channel current-driven stimulator that enables stimulation via any of the 64 electrodes. The stimulus current amplitudes and channels are set in the [Acquire MED64R2 Data w/Stim] module in the MED64 Mobius software. Please refer to the Mobius Tutorial for setting up the stimulation parameters. - Page 11 The incoming stimulus artifacts’ amplitude often exceeds 5 mV, the maximum input voltage for the MED64 amplifier, causing a temporary saturation. The amplifier needs some time to recover. This delay becomes larger in proportion to the stimulation output voltage (Vs). The electrode often needs longer time to discharge than to charge.
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Page 12: Stimulus Current To Be Applied To The Electrodes
Stimulus Current to be Applied to Electrodes As described in the previous section, the applied current charges the electrical double-layer capacitor and causes the voltage (Vc) to change (Fig.7). When the voltage (Vc) rises beyond 1V, the electrode will undergo electrolysis and release H2 gas. -
Page 13: Warranty
It does NOT cover damage incurred during shipment or problems which are caused by products not supplied by Alpha MED Scientific. In addition, this warranty does not cover problems resulting from alteration, accident, misuse, neglect, faulty installation, maladjustment of user controls, improper maintenance, modifications or service by anyone other than AMS or damage attributable to acts of God. - Page 14 September 1, 2011 Alpha MED Scientific Inc. Manufactured by Alpha MED Scientific Inc. Saito Bio-Incubator 209, 7-7-15, Saito-asagi, ©2011 Alpha MED Scientific Inc. Ibaraki, Osaka 567-0085, Japan Phone: +81-72-648-7973 FAX:+81-72-648-7974 http://www.med64.com support@med64.com...
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