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Waters Alliance iS User Manual

Column heater cooler
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Alliance iS Column Heater
Cooler (CHC)
User Guide
715008685
Copyright © Waters Corporation 2023
Version 02
All rights reserved

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Summary of Contents for Waters Alliance iS

  • Page 1 Alliance iS Column Heater Cooler (CHC) User Guide 715008685 Copyright © Waters Corporation 2023 Version 02 All rights reserved...

  • Page 2: Table Of Contents

    2 Safety advisories....................... 12 2.1 Warning symbols..........................12 2.2 Notices............................13 2.3 Required protection........................13 2.4 Warnings that apply to all Waters instruments and devices............14 2.5 Electrical symbols...........................18 2.6 Handling symbols........................... 19 July 14, 2023, 715008685 Ver. 02 Page ii...
  • Page 3 4.1 CHC power and network connections.................... 22 4.2 Setting up the instrument....................... 23 4.2.1 Replacing the column......................23 4.2.2 Powering-on the Alliance iS Column Heater Cooler (CHC)..........26 5 Daily routine analysis....................27 5.1 Using Empower software for system operation................27 5.2 Operation below ambient temperature................... 27 6 Disposal protocols....................

  • Page 4: General Information

    This document is believed to be complete and accurate at the time of publication. In no event shall Waters Corporation be liable for incidental or consequential damages in connection with, or arising from, its use. For the most recent revision of this document, consult the Waters website (www.waters.com).

  • Page 5: Electrical Power Safety Notice

    1.3.2 Electrical power safety notice Do not position the device so that it is difficult to disconnect the power cord. 1.3.3 Equipment misuse notice If equipment is used in a manner not specified by its manufacturer, the protection provided by the equipment may be impaired.
  • Page 6 For compliance with Waste Electrical and Electronic Equipment legislation, contact Waters Corporation for the correct disposal and recycling instructions For indoor use only No pushing Do not connect to an LC system...

  • Page 7: Audience And Purpose

    HPLC (High Pressure Liquid Chromatography) separations for the Alliance iS system. The CHC assembly can provide temperature to the column from 4 °C to 90 °C. If the LC column is equipped with a passive NFC tag (13.56 MHz), it is read when the front door of the CHC is closed.

  • Page 8: Near Field Communications (Nfc)/Rfid Aspects

    1.5.2 Near field communications (NFC)/RFID aspects The Alliance iS Column Heater Cooler (CHC) is used with the Alliance iS HPLC System. The CHC can be equipped with NFC/RFID technology. The national approvals associated with this RF feature are associated only with the CHC and not with other sections of the system or the system in its entirety.

  • Page 9: Other Country-Specific Emc Considerations

    être colocalisé ou fonctionner en association avec une autre antenne ou émetteur. IC: 29985-CHCPHC001 1.5.5 Other country-specific EMC considerations The following country-specific considerations apply to the use of the Alliance iS Column Heater Cooler (CHC). Brazil Este equipamento não tem direito à proteção contra interferência prejudicial e não pode causar interferência em sistemas devidamente autorizados.

  • Page 10: Additional Resources

    เครื ่ อ งโทรคมนาคมและอุ ป กรณ์ น ี ้ ม ี ค วามสอดคล้ อ งตามมาตรฐานหรื อ ข้ อ กํ า หนดทางเทคนิ ค ของ กสทช. 1.6 Additional resources Waters provides the following additional resources to ensure your continued success with our products.

  • Page 11: Contacting Waters

    1.7 Contacting Waters Contact Waters with technical questions regarding the use, transportation, removal, or disposal of any Waters product. You can reach us through the Internet, telephone, fax, or conventional mail. Contact method Information www.waters.com The Waters website includes contact information for Waters locations worldwide.

  • Page 12: Safety Advisories

    Heed all warnings when you install, repair, or operate any Waters instrument or device. Waters accepts no liability in cases of injury or property damage resulting from the failure of individuals to comply with any safety precaution when installing, repairing, or operating any of its instruments or devices.

  • Page 13: Notices

    Warning: (Risk of contacting corrosive substances.) Warning: (Risk of exposure to a toxic substance.) Warning: (Risk of personal exposure to laser radiation.) Warning: (Risk of exposure to biological agents that can pose a serious health threat.) Warning: (Risk of tipping.) Warning: (Risk of explosion.) Warning:...

  • Page 14: Warnings That Apply To All Waters Instruments And Devices

    2.4 Warnings that apply to all Waters instruments and devices When operating this device, follow standard quality-control procedures and the equipment guidelines in this section. Warning: Changes or modifications to this unit not expressly approved by the party responsible for compliance could void the user’s authority to operate the equipment.
  • Page 15 Warning: Use caution when working with any polymer tubing under pressure: • Always wear eye protection when near pressurized polymer tubing. • Extinguish all nearby flames. • Do not use tubing that has been severely stressed or kinked. • Do not use nonmetallic tubing with tetrahydrofuran (THF) or concentrated nitric or sulfuric acids.
  • Page 16 Avvertenza: Fare attenzione quando si utilizzano tubi in materiale polimerico sotto pressione: • Indossare sempre occhiali da lavoro protettivi nei pressi di tubi di polimero pressurizzati. • Spegnere tutte le fiamme vive nell'ambiente circostante. • Non utilizzare tubi eccessivamente logorati o piegati. •...
  • Page 17 • 非金属チューブには、テトラヒドロフラン (THF) や高濃度の硝酸または硫酸など を流さないでください。 • 塩化メチレンやジメチルスルホキシドは、非金属チューブの膨張を引き起こす場合 があり、その場合、チューブは極めて低い圧力で破裂します。 This warning applies to Waters instruments fitted with nonmetallic tubing or operated with flammable solvents. Warning: The user shall be made aware that if the equipment is used in a manner not specified by the manufacturer, the protection provided by the equipment may be impaired.

  • Page 18: Electrical Symbols

    警告： 使用者必須非常清楚如果設備不是按照製造廠商指定的方式使用，那麼該設備 所提供的保護將被消弱。 경고 제조업체가 명시하지 않은 방식으로 장비를 사용할 경우 장비가 제공하는 보호 수단이 제대로 작동하지 않을 수 있다는 점을 사용자에게 반드시 인식시켜야 합니다. 警告 ユーザーは、製造元により指定されていない方法で機器を使用すると、機器が 提供している保証が無効になる可能性があることに注意して下さい。 2.5 Electrical symbols The following electrical symbols and their associated statements can appear in instrument manuals and on an instrument’s front or rear panels.

  • Page 19: Handling Symbols

    2.6 Handling symbols The following handling symbols and their associated statements can appear on labels affixed to the packaging in which instruments, devices, and component parts are shipped. Symbol Description Keep upright! Keep dry! Fragile! Use no hooks! Upper limit of temperature Lower limit of temperature Temperature limitation July 14, 2023, 715008685 Ver.

  • Page 20: Alliance Is Column Heater Cooler (Chc) Overview

    3 Alliance iS Column Heater Cooler (CHC) overview The Waters Alliance iS Column Heater Cooler (CHC) (279004951) supports the Alliance iS HPLC system functions for LC separations. Refer to the system guides for all system-level functions. Figure 3–1: Alliance iS Column Heater Cooler (CHC) July 14, 2023, 715008685 Ver.

  • Page 21: Features

    Figure 3–2: Alliance iS Column Heater Cooler (CHC) with door open 3.1 Features The Alliance iS Column Heater Cooler (CHC) supports the Alliance iS HPLC System with the following features and capabilities: • Supports HPLC columns of various sizes, lengths, and diameters. The CHC can accommodate columns up to 8.0-mm ID and up to 300-mm length.

  • Page 22: Instrument Startup

    4 Instrument startup This section helps you set up and start your Waters system. Proper setup is critical to successful operation of the system. The Alliance iS Column Heater Cooler (CHC) comes preassembled as part of the Alliance iS HPLC System. Refer to the Alliance iS HPLC System startup instructions.

  • Page 23: Setting Up The Instrument

    The column, compartment, tubing, fittings, and door liner can be hot. To remove the existing column: If installing a Waters-branded column, this procedure requires no tools. You can easily replace it using the column clips and tool-free fittings. Note: Before removing the column, you can flush the column using the system touchscreen or Touchscreen App.
  • Page 24 Figure 4–2: Removing the column from the black clips Top black clip Bottom black clip c. Locate the fasteners that secure the tubing at the top of the column compartment, and then remove the tubing from fasteners 2 through 4 only. Tip: You will not remove the tubing from fastener 1 because it secures the tubing to another module and should remain connected.
  • Page 25 Figure 4–3: Four fasteners that secure the tubing d. Unscrew the fitting located on the bottom of the column and set it aside to install the new column. e. Unscrew the fitting located on the top of the column and set it aside to install the new column.

  • Page 26: Powering-On The Alliance Is Column Heater Cooler (Chc)

    Verify that the tubing is situated inside the compartment before you close the column compartment door. 4.2.2 Powering-on the Alliance iS Column Heater Cooler (CHC) After the system is plugged in and powered-on, the CHC has power. July 14, 2023, 715008685 Ver. 02...

  • Page 27: Daily Routine Analysis

    5 Daily routine analysis 5.1 Using Empower software for system operation Refer to the Alliance iS HPLC System documentation. 5.2 Operation below ambient temperature When setting the compartment temperature lower than the ambient temperature, consider disabling the leak sensor. Condensation can trigger the leak sensor, giving a false indication of a leak and stopping operation of the system.

  • Page 28: Disposal Protocols

    6 Disposal protocols Disposal of system components is performed either by Waters personnel or by the customer per local jurisdiction. 6.1 Description of constituent materials For detailed descriptions of Waters materials, see Safety Data Sheets on waters.com. 6.2 Disposal of system components Disposal of system components is performed either by Waters personnel or by the customer per local jurisdiction.

  • Page 29: Solvent Considerations

    Additionally, consult the safety representative for your organization regarding its protocols for handling such materials. This section covers the solvent considerations necessary when operating the Alliance iS System. This information applies only to the Alliance iS System and components.

  • Page 30: Water

    7.1.4 Water Use water only from a high-quality water purification system. Notice: Using 100% water can cause microbial growth. Waters recommends changing 100% water solutions daily. Adding a small amount (~10%) of an organic solvent prevents microbial growth. If the water system does not deliver filtered water, filter the water through a 0.2-μm membrane filter.

  • Page 31: Specifications

    Technical Service organization for additional information about specifications. 8.1 Instrument specifications The tables in this section detail the specifications for the Alliance iS Column Heater Cooler (CHC). Refer to the Alliance iS HPLC System Guide for system-level specifications. 8.1.1 Environmental specifications Table 8–1: Alliance iS Column Heater Cooler (CHC) environmental specifications...

  • Page 32: Physical Specifications

    Table 8–2: Alliance iS Column Heater Cooler (CHC) electrical specifications (continued) Attribute Specification Line frequency 50–60 Hz Power consumption 350 VA Protection class Class 1 Overvoltage category Pollution degree a. The insulating scheme used in the instrument to protect from electrical shock. Class I identifies a single level of insulation between live parts (wires) and exposed conductive parts (metal panels), in which the exposed conductive parts are connected to a grounding system.
  • Page 33 Table 8–4: Alliance iS Column Heater Cooler (CHC) physical specifications (continued) Attribute Specification Width 11.4 cm (4.5 inches) Depth 61.7 cm (24.3 inches) Weight 11.3 kg (25.0 lbs) July 14, 2023, 715008685 Ver. 02 Page 33...

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