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MGI MGISP-NE32RS User Manual

Automated nucleic acid extractor
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Part No.: H-020-000233-00
Address:
Building 24, Stage 3.1, BioLake Accelerator, No.388, 2nd Gaoxin Road, East Lake
High-Tech Development Zone, 430075, Wuhan, P.R.China
E-mail:
MGI-service@mgi-tech.com
Website:
www.mgi-tech.com
Automated Nucleic Acid Extractor
MGISP-NE32RS
Research Use
Only
W u h a n M G I T e c h C o . , L t d .
Version: 4.0

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  • Page 1 Part No.: H-020-000233-00 Automated Nucleic Acid Extractor MGISP-NE32RS Version: 4.0 Address: Building 24, Stage 3.1, BioLake Accelerator, No.388, 2nd Gaoxin Road, East Lake Research Use High-Tech Development Zone, 430075, Wuhan, P.R.China Only E-mail: MGI-service@mgi-tech.com W u h a n M G I T e c h C o . , L t d .
  • Page 2 MGI. Any unauthorized person should not use this manual. MGI does not make any promise of this manual, including (but not limited to) any commercial of special purpose and any reasonable implied guarantee. MGI has taken measures to guarantee the correctness of this manual.
  • Page 3 Revision history Date Version January 13, 2023 Revision March 5, 2021 November 2, 2020 Initial release June 20, 2020...

  • Page 4: Table Of Contents

    Contents Important notes Conventions Safety Components safety Biological safety Symbols Device Label Packaging Introduction Instrument features Intended use Structural composition Features Normal working conditions Transportation and storage conditions Basic parameters Basic performance Software functions Preparations Basic components Front view Rear view Site requirements...
  • Page 5 Peripheral device preparation Check before startup Placement of 96 deep-well plate Startup Operation Operation main interface New/edit file Running files UV lamp setting System setting Date and time setting Language selection Backlight adjustment Motion parameters Prompt tone setting Screen calibration Step name management System update Maintaining the device...
  • Page 6 Manufacturer information European representative information Index...
  • Page 7 - - - T h i s p a g e i s i n t e n t i o n a l l y l e f t b l a n k . - - -...

  • Page 8: Important Notes

    Important notes During the operation or maintenance of the machine, the following safety measures should be taken. Otherwise, the guard provided by the machine is likely to be damaged, the rated safety level to be reduced, and the rated operation conditions to be affected.

  • Page 9: Conventions

    Conventions The following table describes conventions that are used in the manual: Item Description Indicates that the operator should operate the device by following the instructions. Otherwise, it might result in personal injury. Indicates that the operator should operate the device by following the instructions.
  • Page 10 A.C. power’s grounding should be reliable for fear of an electric shock. The 3-pin plug with the machine’s power cable is a safety device that should be matched with a grounded socket. Never let the third ground pin floating. If the 3-pin plug cannot be inserted, it is recommended to ask an electrician to install an appropriate power socket.

  • Page 11: Components Safety

    If the machine is set aside for a long time, it is recommended to disconnect the power cable from the mains supply and cover the device with a piece of soft cloth or plastic to prevent dust from entering. Once one of the following events occurs, you are suggested to disconnect the power cable from the mains, and contact the distributor or ask a certificated maintenance personnel for help.

  • Page 12: Symbols

    Symbols Device The following table describes symbols on the device: Symbol Name Description Indicates connection to the mains "ON" (power) supply. Indicates disconnection from the "OFF" (power) mains supply. General warning Signifies a general warning. sign Warning; biological Warns of a hazard from a biological hazard hazard.

  • Page 13: Label

    Label The following table describes symbols on the label: Symbol Name Description I n d i c a t e s a d e v i ce t h a t i s fo r Research Use research use only, and cannot be Only used for clinical diagnosis I n d i c a t e s t h e m e d i c a l d e v i c e...

  • Page 14: Packaging

    Symbol Name Description I n d i c a t e s t h a t w a s t e e l e c t r i c a l and electronic equipment must not be disposed of as unsorted m u n i c i p a l w a s t e a n d m u s t b e WEEE symbol collected separately.
  • Page 15 Symbol Name Description Indicates the temperature limits to Temperature limit which the medical device can be safely exposed. Indicates the range of humidity to Humidity which the medical device can be limitation safely exposed. Indicates the range of atmospheric Atmospheric pressure to which the medical pressure limitation device can be safely exposed.

  • Page 16: Introduction

    Introduction This chapter mainly introduces the features, intended use, and structure composition of the instrument.

  • Page 17: Instrument Features

    Instrument features This product adopts a magnetic bead extraction technology to extract and purify nucleic acid through precision transmission and controlling step motor by single chip microcomputer. It has features as follows: small volume, light weight, low noise, full-closed workaround; Embedded real-time operating system; Transparent working chamber facilitating the observation of working conditions;...

  • Page 18: Features

    Features This chapter mainly introduces the usage, transportation and storage conditions of the instrument, as well as its basic parameters, performance and functions.

  • Page 19: Normal Working Conditions

    Normal working conditions z Atmospheric pressure: 80 kPa to 106 kPa z Altitude: up to 2000 m (6561.68 ft) z Ambient temperature: 10 ℃ to 30 ℃ (50 ℉ to 86 ℉ ) z Relative humidity: 20% to 70%, non-condensing z Power supply: 100 V to 240 V~, 50/60 Hz z Voltage fluctuation: ±10% z Pollution degree: 2...

  • Page 20: Basic Performance

    Sound prompt function z Fault protection and alarm function z UV lamp on and timed off z Upgrade by USB drive The above software features are for reference only. MGI reserves the right to change the software without notice.
  • Page 21 - - - T h i s p a g e i s i n t e n t i o n a l l y l e f t b l a n k . - - -...

  • Page 22: Preparations

    Preparations This chapter mainly describes the structure, the functions of screen and keys on the screen, as well as the preparations before the startup. Before the first operation of this instrument, please read this chapter carefully and make sure you are familiar with the contents of this chapter.

  • Page 23: Basic Components

    Basic components Front view Figure 1 Front view Name Name Enclosure 96 deep-well plate position Closing cover Operating room Display...

  • Page 24: Rear View

    Rear view Figure 2 Rear view Name Description USB port Connects to the external memory. Serial port Connects to the scanner. Powers on or off the device. z Switch to the position to power on Power switch the device. z Switch to the position to power off the device.

  • Page 25: Site Requirements

    Site requirements Ensure that enough space is provided around the device for ventilation, cable connection, and power switch operation. The following figure indicates distances that are required for optimal operation and access. ≥300 mm (11.8 inches) Device ≥300 mm ≥300 mm (11.8 inches) (11.8 inches) Operation area...

  • Page 26: Check Before Startup

    Check before startup The following contents should be confirmed before powering on: z Whether the power supply meets the required voltage of the instrument; Refer to Normal working conditions on Page 12 of this manual for power requirements. z Confirm that the power cord plug has been reliably inserted into the power socket;...
  • Page 27 - - - T h i s p a g e i s i n t e n t i o n a l l y l e f t b l a n k . - - -...

  • Page 28: Operation

    Operation This chapter explains in detail how to edit, review, and delete files, and how to run/stop files. It also introduces the meaning of protection interface in the process of file running.

  • Page 29: Operation Main Interface

    If there is any abnormal sound or display after the instrument is switched on, or there is a fault alarm during the instrument self-testing, please switch off the power immediately and contact the technical support. Operation main interface After the system is started, the main interface is displayed. The operation state of the instrument is displayed at the center of the interface.

  • Page 30: Run

    Item Description Copy the selected file to the default u-disk directory (under Export the \pcrex\MGI of u-disk directory). Delete Delete the selected file from the instrument. After creating the default file, go to the file editing interface to edit the new file.
  • Page 31 The following image shows the history browsing interface. Figure 6 History browsing interface A list of 9 files that were last edited and run is in the middle. The current selected file is displayed in white. Click the current selected file to enter the file editing interface.

  • Page 32: New/Edit File

    In the center is the " .ebr "file list that conforms to the file name standard in the default directory of USB drive (under the \pcrex\MGI of u-disk directory) (a legal file name consists of an English letter, a number, and an underscore, and a filename that does not include a suffix is no longer than 12 characters).
  • Page 33 The currently selected step is displayed in a different color. Click the unselected step column to select the specified step. It can save up to 30 steps program, if there are more than 5 steps, the rest of steps are to be paged by pressing the up/down button. Add or remove steps by clicking Add or Remove.
  • Page 34 Click the list box beside the name, and the name selection list will pop up. Figure 11 Name selection list It allows users to select the appropriate name in a pre-set list of step names to describe the action that the step performs. See Step name management on Page 35 for how to add or remove preset step names.
  • Page 35 The mixing parameter allows user to set up a mixing step for up to three periods. If the mixing step is not to be used, set the time to 00:00. The mixing speed can be selected from the option list by clicking on the mixing steps list.

  • Page 36: Running Files

    Click Save/Run to display the file save interface, as shown in the figure below. Figure 15 File save interface You can use the on-screen keyboard to input the file name. If you do not want a file to be viewed, modified, or run, you can enter a password.

  • Page 37: Uv Lamp Setting

    z Click Run in the file save interface. Figure 16 Running files interface The lysis and elution temperatures are displayed on top of the running interface. The lower left side of the interface shows the steps undergoing, including waiting time, mixing time, binding time, and remaining time.

  • Page 38: System Setting

    Figure 17 UV lamp setting interface System setting Click System in the operation main interface to enter the system setting interface . Figure 18 System setting interface Eight setting entries are provided. Click Main in the upper right corner to return to the main interface.

  • Page 39: Date And Time Setting

    Date and time setting Click Date&Time in the system setting interface, enter the Date & Time setting interface, and click OK or Cancel after setting time or date to return to the system setting interface. Figure 19 Date and time setting interface Language selection In the system settings interface, click Language to enter the language settings interface, select Chinese or English, click OK or...

  • Page 40: Backlight Adjustment

    Backlight adjustment Click Back Light in the system setting interface to enter the backlight adjustment interface. Turn up/down screen brightness by clicking and dragging the scroll bar, or by clicking certain spot in the scroll bar to modify the position of the indicator sign, and then click OK or Cancel to return to the system setting interface.

  • Page 41: Prompt Tone Setting

    Prompt tone setting Click Beep in the main interface to enter the prompt tone setting interface. After setting the alarm prompt, the keyboard prompt, and the closing prompt, click OK or Cancel to return to the system setting interface. Figure 22 Prompt tone setting interface Screen calibration In the operation main interface, click Touch Calibrate to enter the screen calibration interface, and click the center of the cross icon...

  • Page 42: Step Name Management

    Step name management Click Name Manage in the system setting interface to enter the step name management interface. The interface displays all the steps currently, and you can create, delete and clear the customed step name tags. Click Exit to return to the system setting interface. Figure 24 Step name management interface Item Description...
  • Page 43 After selecting the program that needs to be upgraded (according to the upgrade file in the USB drive, automatically list the items available for upgrade), click Upgrade to start the firmware upgrade process, and click Cancel to return to the main interface. Figure 25 System upgrade interface After the upgrade is completed, follow the screen prompt to shutdown the device, remove the upgrade USB drive, and restart the...

  • Page 44: Maintaining The Device

    Maintaining the device This chapter mainly introduces the possible fault phenomenon, causes analysis and solutions of this instrument.

  • Page 45: Cleaning The Device

    Cleaning the device z We do not recommend that you use other disinfectants or wash solutions except for those that are mentioned in this manual. Because other solutions are not verified for use and their effects to the device are unknown. z If you have questions about the compatibility of wash solutions, contact the technical support.

  • Page 46: Fault Analysis And Troubleshooting

    Fault analysis and troubleshooting If malfunction occurs during operation, the device beeps or a message appears on the screen. Follow the on-screen prompt to troubleshoot and solve the problem. The following table lists some of the problems and possible solutions. If problems that are not mentioned in this manual arise, or if you need additional assistance, contact the technical support.

  • Page 47: Disposal Of The Device

    Disposal of the device The service life of this device is five years, which is determined by the simulated service life evaluation method. For the date of manufacture, refer to the label on the device. Perform the maintenance according to the requirements mentioned in this manual.

  • Page 48: Compliance Information

    Compliance information The device complies with following standards: Item Standard z IEC 61326-1:2012 Electromagnetic Electrical equipment for measurement, control compatibility and laboratory use - EMC requirements - Part 1: General requirements z IEC 61010-1:2010, AMD1:2016 Safety requirements for electrical equipment for measurement, control, and laboratory use - Part 1: General requirements z IEC 61010-2-081:2019...
  • Page 49 - - - T h i s p a g e i s i n t e n t i o n a l l y l e f t b l a n k . - - -...
  • Page 50 Manufacturer information Manufacturer Wuhan MGI Tech Co., Ltd. Address Building 24, Stage 3.1, BioLake Accelerator, No.388, 2nd Gaoxin Road, East Lake High- Tech Development Zone, 430075, Wuhan, P.R.China Technical support Wuhan MGI Tech Co., Ltd. Technical support E-mail MGI-service@mgi-tech.com...
  • Page 51 - - - T h i s p a g e i s i n t e n t i o n a l l y l e f t b l a n k . - - -...
  • Page 52 European representative information Name Latvia MGI Tech SIA Address Mārupes nov., Mārupes pag., "Lidostas parks", LV-2167, Latvia...
  • Page 53 - - - T h i s p a g e i s i n t e n t i o n a l l y l e f t b l a n k . - - -...
  • Page 54 Index Fuse specification 5 Normal working conditions 12 Peripheral device 18 Safety 2 Startup 19 System update 35 Troubleshooting 39...
  • Page 55 - - - T h i s p a g e i s i n t e n t i o n a l l y l e f t b l a n k . - - -...

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