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LiCONiC BiOLiX! STC Operating Manual

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Storage
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STC

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Summary of Contents for LiCONiC BiOLiX! STC

  • Page 1: Bio.li.x

    Operating Manual BiO.Li.X! Storage Range...
  • Page 2 No license is granted by acquisition of the product for any patent or patent rights of LiCONiC. If the user does not follow the instructions given in this manual, LiCONiC does not take any responsibility for injuries or damages caused by the LiCONiC product.

  • Page 3: History Page

    History Page Document Change History Date Version Changes Author 19.08.2022 Initial Realease of updated Manual Ralf Kindle BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 4: Table Of Contents

    Table of Contents BiO.Li.X! ___________________________________________________________________ 1 History Page _______________________________________________________________ 3 Introduction _______________________________________________________________ 8 About the Product and its Manual ______________________________________________ 8 Intended Use __________________________________________________________________ 8 Unintended Use________________________________________________________________ 8 Product Identification ___________________________________________________________ 8 Scope of Delivery _______________________________________________________________ 8 General ______________________________________________________________________ 9 Definitions ____________________________________________________________________ 9 Target User Group ______________________________________________________________ 9 Importance of the Safety Instructions_______________________________________________ 9...
  • Page 5 Backup solutions for Kiwi Stores ______________________________________________ 22 Overview ____________________________________________________________________ 22 Auxiliary Refrigeration __________________________________________________________ 22 4.2.1 Redundant Refrigeration STC DF _______________________________________________ 22 Auxiliary Refrigeration ULT ______________________________________________________ 22 CO2 Backup cooling ____________________________________________________________ 22 LN2 Backup cooling ____________________________________________________________ 23 Tube Handling _____________________________________________________________ 24 General _____________________________________________________________________ 24 Options _____________________________________________________________________ 25 5.2.1...
  • Page 6 Electrics _____________________________________________________________________ 48 9.4.1 Overview __________________________________________________________________ 48 9.4.2 Electrical Connections Store ___________________________________________________ 48 9.4.3 Electrical Connections Cooling units _____________________________________________ 49 9.4.4 Electrical Connections Interface ________________________________________________ 50 9.4.5 Requirements ______________________________________________________________ 51 Gassing Installation ____________________________________________________________ 52 9.5.1 Kiwi Store Gassing and Backup Options __________________________________________ 52 9.5.2 Safety Information __________________________________________________________ 52 9.5.3...
  • Page 7 Software _________________________________________________________________ 82 Sample Management Software _____________________________________________ 82 19.1 Order File ____________________________________________________________________ 82 19.1.1 Simple order file __________________________________________________________ 82 19.1.2 Complex order file ________________________________________________________ 83 19.2 Import – Export Interface _______________________________________________________ 84 19.2.1 Import __________________________________________________________________ 85 19.2.2 Export __________________________________________________________________ 91 19.2.3 Exception Plates __________________________________________________________ 94 19.2.4...

  • Page 8: Introduction

    The LiCONiC BiOLiX! Store is intended for storage, identification and transfer of Microplates and Tubes. It is to be applied exclusively in the research field. The LiCONiC BiOLiX! Store is intended to work as a stand-alone unit or an element in an automated system.

  • Page 9: General

    General The LiCONiC BiOLiX! Store is a complete product for end users. Setup of equipment is conducted by LiCONiC Engineers or by LiCONiC trained and certified personnel. Definitions Operator: Any person who uses the equipment for its intended purpose. System Integrator:...

  • Page 10: Labels

    Labels Throughout this publication, Warning Notices are to be interpreted as follows: WARNING! Indicates the possibility of severe personal injury, loss of life or equipment damage if instructions are not followed. CAUTION! Indicates the possibility of severe equipment damage if instructions are not followed.

  • Page 11: Extreme Temperature Hazards

    Prior to executing any maintenance task on the instrument or sending it, or parts of it for repair, the instrument or the parts have to be thoroughly decontaminated. 1.10.5 Extreme Temperature Hazards All surfaces inside the storage chambers, interface and some parts of the refrigeration may be considered as potentially dangerous if touched without sufficient protective clothing.

  • Page 12: General Safety Regulations

    Only an authorized Engineer shall carry out inspection, maintenance and repair tasks. 1.11.3 Spare Parts to be used Only original LiCONiC Spare Parts may be used. If other parts are used during the normal warranty period, the manufacturer's guarantee may be invalidated. 1.11.4 Modifications Modifications shall only be carried out by an authorized Engineer.

  • Page 13: General

    General Biolix STC Kiwi Stores Kiwi Store The Biolix STC Kiwi Store is the most compact Storage with Integrated Handling that covers tube and plate storage needs at –20°C and –80°C. The Kiwi Store Series offers dry climate storage. The systems are intended for fixed installation at the customer site.

  • Page 14: Biolix Stc Kiwi Store Overview

    As for the customized nature of the systems as following some examples of systems and their configurations are shown. The pictures are of exemplary nature. For specific system details and system dimensions please contact LiCONiC AG. 2.3.1 STC7k0 DF 2.3.2 STC16k0 ULT BiO.Li.X!

  • Page 15: Stc18K5 Ult

    2.3.3 STC18k5 ULT 2.3.4 STC70k5 ULT 2.3.5 STC101k ULT BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 16: Stc118K Ult

    2.3.6 STC118k ULT BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 17: Configuration

    Configuration: Show in the following examples are basic configurations. This is a selection. Due to the customized nature of the systems a large range of possible configurations is possible due to the modular nature of the systems. 2.4.1 Side Load System This is the most common configuration.

  • Page 18: Front Load System

    2.4.2 Front Load System Systems which are configured with the interface at the narrow side are called front load systems. The physical configuration is missing the front fixed Trolley allowing for connection between store and interface. BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 19: Combinations

    The previously mentioned configuration can be combined for bigger storage capacities. As an example, a tandem system is shown consisting of two storage handling systems and one interface. Other combinations are possible, please contact Liconic AG for specific requests. BiO.Li.X! STC V1.0...

  • Page 20: Options

    Options Climate Overview Name Temperature Humidity DF Deep Freezer -20..00°C 02..45%RH ULT Ultra Low Temperature -80°C n.a. The DF Stores are designated for the use as compound storage, whereas the ULT version is mainly for Biobanking use. Cooling Within all units the air is actively dried by forcing the air through an evaporator. This allows cooling and actively drying the air.

  • Page 21: Humidity

    Humidity All units are equipped with an RH-Sensor. This allows displaying the humidity inside the storage chamber. A very high-quality sensor is used for this purpose. Quality and accuracy of the sensor is maintained by the Swiss Federal Office of Metrology and the Swiss Accreditation Service.

  • Page 22: Backup Solutions For Kiwi Stores

    Backup solutions for Kiwi Stores Overview Name Temperature Principle Auxiliary Refrigeration DF -20..00°C Refrigeration unit Auxiliary Refrigeration ULT -80°C Refrigeration unit CO2 Backup -20°C Evaporator for LN2 Backup -80°C Evaporator for The Kiwi Store auxiliary refrigeration units mainly cover the case of a failure of one main cooling unit whereas the gas backup solutions are made to cover power outages.

  • Page 23: Ln2 Backup Cooling

    If the CO2 backup cooling is coming into action large amounts of CO2 are released through the options exhaust. Therefore the exhaust needs to be lead out of the building to not endanger personnel working in the area of the system. WARNING ! ➢...

  • Page 24: Tube Handling

    The Kiwi units are distinguished through the capability to hold a tub handling unit under climatized conditions. The tube Handling is able to handle most tube types. The tube handling is integrated into the Liconic System and allows it to work under control climate conditions.

  • Page 25: Options

    SBS 138 SBS 48 SBS 60 The use of HD formats on existing devices is possible but should be confirmed with a Liconic representative. Software configuration changes and teaching is required in any case. 5.2.2 Revolving Head Option This option allows the tube handling to hold two endeffectors for different tube formats.

  • Page 26: Side Code Reader With Rotating Endeffector

    5.2.3 Side Code Reader with Rotating Endeffector For tubes with side labels a solution is offered to read such labels. The reader is located at the side of the actual picking are. Each tube needs to be lifted up individually to be read. The reader is capable to identify 1D Barcodes and 2D Codes.

  • Page 27: Custom Tube Handlings

    5.2.6 Custom Tube Handlings For specific application custom solutions may be offered. These custom solutions will build on the mentioned features or a combination of them. Please contact Liconic for further information. BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 28: Identification

    Identification Plate Presence Sensor A Plate Presence Sensor is installed under the shovel on the Handling Assembly. It allows the check the present of the plates stored in the stackers. Plate Present Sensor is an optical sensor. Barcode Reader Camera PPS - Plate Presence Sensor Shovel Assembly...

  • Page 29: Barcode Reader

    Barcode reader A Bar Code Reader is installed on the Lift Assembly. It allows the reading of Bar Codes on plates stored in the cassettes. Bar Codes have to be printed on the shorter side of the plates and have to face outwards to the Lift Assembly. Barcode Reader Camera Shovel Assembly...
  • Page 30 Barcode Specifications • Light Source: Semiconductor Laser • Wavelength: 650nm • Output: 1.0mW • Class: FDA: Class II IEC 825-1 11.1993: Class 2 DIN EN 608251 07.1994: Klasse 2 Reading Bar Width: 0.125 – 1.0 mm • Reading Bar Width: 0.15 –...

  • Page 31: Plate Code Reader 1D/2D

    6.2.2 Plate Code Reader 1D/2D Optional a camera-based reader is available providing the possibility to read 1D and 2D codes. This reader is used when it is required to identify plates with 2D codes or the conditions for reading require the flexibility of this reader. Supported Barcode Types The barcode reader recognizes the following barcode types.

  • Page 32: Falcon Eye Fe2D-138 Scanner

    Falcon Eye FE2D-138 scanner A 2D code whole rack scanner can be integrated into the systems. It allows the reading of 2D Codes of a whole rack at once under controlled climate condition. To read the 2D codes, the rack needs moved as a whole to the reader. 6.3.1 Supported 2D code Types The optional 2D code reader recognizes the following 2D code types.

  • Page 33: Accessories

    The System Capacity depends on the cassette pitch configuration. The cassette pitch is suited to the used labware. The Kiwi Store can handle almost every plate or tube racks in SBS format currently available on the market. For optimum performance LiCONiC offers a variety of cassettes. Buffer Cassette...

  • Page 34: Transfer Stations

    Transfer Stations LiCONiC offer a wide range of transfer stations for different applications. Please contact LiCONiC for detailed information on compatibility and special hand off requirements. Slide Station The STC systems require by default a slide station to bridge the distance from the interior robotic to the outside.

  • Page 35: System Installation

    System Installation BiOLiX Store STC installation Complete System Overview 9.1.1 3D-View Main Cooler Backup Cooler Dryer Service Area Cold Store Interface Interface Cooling Unit 9.1.2 Top view Main Cooler 400 VAC Insulation Panels Aux. Cooler 400VAC Cold Store –80°C Backup Cooler Application Interface Integration...

  • Page 36: Panel Locations

    9.1.3 Panel Locations 3.2 Electrical Connection Store 3.4 Electrical Connection Interface 2.4 LN2 inlet and exhaust Store Backup Auxiliary Interface Cooling Store Main Cooling 3.3 Electrical Connection 2.6 Cooling Water Cooling unit Connection BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 37: General Requirements

    3.5 m (If not specified differently) Ground cooling 10W/m^2 (Cooling energy loss passed on to the ground) Floor load Recommended 1'000 kg/m^2 (for smaller load specifications please consult clearance recommendations with Liconic Applications team, case-by-case approval required) Point load 250 kg Heat dissipation <...

  • Page 38: Refrigeration

    Refrigeration 9.3.1 Refrigeration Elements Overview Cold Store –80°C Backup Cooler Main Cooler LN2 Dewar 2 400 VAC Backup Cooler Aux. Cooler LN2 Dewar 1 400 VAC BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 39: Electrical Refrigeration Principles Ult

    9.3.2 Electrical Refrigeration Principles ULT 1 stage Condenser Water Cooler Inlet Water Cooler Outlet Stage R410A/R449A Stage R508b 9.3.3 Electrical Refrigeration Principles DF Water Cooler Inlet Coolant R410A/R449A Water Cooler Outlet BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 40: Cold Water Cooler

    9.3.4 Cold Water Cooler External water cooler Cold water in typ. ~14°C Room AC STC cooler unit Liconic STC Store STC Cold water return typ. ~30°C BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 41: Connections Cooler To Cold Store

    9.3.5 Connections Cooler to Cold Store Auxiliary Cooler Back plane cold store LN2 Inlet Main Cooler LN2 Exhaust Connections Main Cooler Connections Dryer Power In Main Cooler Main Cooler Cold store Power In aux. Cooler Aux. Cooler Connections auxiliary cooler Cooler BiO.Li.X! STC V1.0...

  • Page 42: Typical Water Cooler Integration

    9.3.6 Typical Water Cooler Integration Cooling water return line Cooling water inlet Water shut-off valve BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 43: Cooling Water Connection

    9.3.7 Cooling Water Connection ULT Cooling Unit Refrigeration cooling water OUT ¾” Refrigeration cooling water IN ¾“ BiO.Li.X! STC V1.0 RKi, 19.08.2022...
  • Page 44 DF Cooling Interface Refrigeration cooling water OUT ¾” Refrigeration cooling water IN ¾“ BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 45: Requirements Cooling Water

    3/4" male Individual connections for main and redundant cooling Mixture of Water with Glycol may require modifications of refrigeration components. Confirmation by Liconic in such cases mandatory. Typical pump used for Grundfos CR Series (e.g.: CR 1-8 AN-FGJ-G-E-HQQE or regulated for...
  • Page 46 Requirement Details Water Connections Main: 1x Inlet; 1x Return (per specified cooling unit) Auxiliary: 1x Inlet; 1x Drain/Return Interface Unit: 1x Inlet; 1x Return Auxiliary cooling mandatory to be connected to second (redundant) water circuit or fresh water supply. Drain Peripheral Unit and Storage Dryer may perform regular defrost cycles.

  • Page 47: Ln2 Backup Connections

    9.3.9 LN2 Backup Connections Auxiliary Cooler Chamber cold store Manual shut off valve Automatic valve LN2 Inlet Main Cooler LN2 Exhaust 9.3.10 LN2 Requirements Requirement Details Media Refill intervall Depending on DEWAR-Volume With respect to the Leak rate the DEWAR has to be refilled to maintain the minimum desired backup time.

  • Page 48: Electrics

    Electrics 9.4.1 Overview Power 400VAC main cooler Power 400VAC Power 230VAC auxiliary cooler Interface unit Power 230VAC UPS Store Power 230VAC non UPS Store 9.4.2 Electrical Connections Store BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 49: Electrical Connections Cooling Units

    9.4.3 Electrical Connections Cooling units Communication Power 400VAC cooler Main Power switch IEC 60309 3P+N+PE 400V / 16A ¾” BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 50: Electrical Connections Interface

    9.4.4 Electrical Connections Interface Interface unit comm. Ports Handling / BCR / Tube Picker / 2D-BCR Interface unit low Power 230VAC (handling) Interface unit 230VAC high power (climate) BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 51: Requirements

    9.4.5 Requirements Requirement Details Supply Refrigeration Store 400V / 50Hz 3 Phases (per Main Cooling unit) Fuse: 16A (Type: D ; 3-Phase circuit breaker (coupled)) Connector: CEE Type 611, 16A 5-Pol: 3xL, N, PE (IEC 60309) Phase sequence: clock wise Supply Auxiliary 400V / 50Hz 3 Phases Refrigeration Store (optional)

  • Page 52: Gassing Installation

    Gassing Installation 9.5.1 Kiwi Store Gassing and Backup Options The Kiwi Store series supports a wide selection of gassing and backup options. Typical properties of some commonly used options are described next. There are other gassing options available. Note that each gassing and backup option is linked to specific risks and hazards.
  • Page 53 WARNING ! ➢ In their liquid state inert gases are extremely cold fluids which can cause serious burns when in contact with the skin ➢ A cryogenic spill often gives a low-lying cloud of vapor that creeps along the ground When a cryogenic liquid is released into the atmosphere, it evaporates and forms a dense cloud.
  • Page 54 General Safety Instructions When working with inert gases prevent contact of liquid gas, cold vapors, or "snow" with exposed skin. Prevent entrapment of liquid in closed systems. Use only in well ventilated areas. Compressed gas cylinders contain gaseous and liquid gas at extremely high pressure and should be handled with care.

  • Page 55: Installation Safety Recommendations

    9.5.3 Installation Safety Recommendations Preventive Measures The very first preventive measure is to inform all persons who handle or who use inert gases: • Of the hazard represented by the refraction of oxygen in atmosphere • Of the preventive means to be employed in handling the gases •...
  • Page 56 Testing of Oxygen or Gas Content At present, various types of oxygen analyzers are available, which are often simple and reliable to operate. Such a monitor should at least have • A readout of the actual gas concentration • A settable alarm threshold value •...
  • Page 57 Personnel Protection Depending on the type of work to be performed, and the layout of the premises, the decision to provide additional protection for personnel may be taken on the initiative of the person in charge. Such additional protection may involve: •...

  • Page 58: Backup Refrigeration Installation

    9.5.4 Backup Refrigeration installation On installations preferably choose pressurized liquid gas storage cylinders rather than wall outlets. The use of cylinders will limit the amount of gas being spilled in case of fatal failure. Whenever a wall outlet installation is chosen, make sure that there is a remote shut off valve installed outside the room where the liquid is used.

  • Page 59: Specific Advice For Ln2 Liquid Nitrogen

    9.5.5 Specific Advice for LN2 Liquid Nitrogen Properties of Nitrogen Nitrogen is colorless, odorless and tasteless, as gas or liquid. It is nontoxic and non-flammable at atmospheric temperatures and pressures. A specific gravity of 0.9669 makes nitrogen slightly lighter than air. Nitrogen is mainly found in the atmosphere, where it accounts for 78.1% by volume of the air we breathe.
  • Page 60 In case of an accident evacuate all personnel from the affected area. Persons suffering from lack of oxygen should be removed to fresh air. If victim is not breathing, use trained personnel to administer a supplemental oxygen supply and artificial respiration to support vital functions. If breathing is difficult, administer oxygen.

  • Page 61: Refill Ln2 Liquid Nitrogen Cylinder

    9.5.6 Refill LN2 Liquid Nitrogen cylinder Whenever working with liquid Nitrogen use of personal safety equipment is required. Thermal gloves and protective glasses have to be worn at least. Refill interval of LN2 cylinder is depending on the required minimum backup time and the available LN2 cylinder volume.

  • Page 62: Manual Operation

    Manual Operation Alert System The systems have a combined acoustic / visual alert system. An alert occurs when one or more abnormal statuses occur or when interaction is required. When the system is operating properly there is no alert. The various alerts are distinguished by the alert signal duration and the pause between the signals.

  • Page 63: Doors

    Doors 11.1 User Door The user doors may be opened with the present door handle. They should be kept closed at all times. A spring inside the hinge of the door ensures the door to be closed. When access is necessary it should be for as short as possible periods. In order to avoid condensation and to allow a stable temperature inside the instrument, the glass doors are specially coated.
  • Page 64 CAUTION ! ➢ Use the door handle to open the user door ➢ Keep user door closed when it is not being accessed ➢ Keep user door access to a minimum ➢ seal must firmly close ➢ Keep seal clean WARNING ! ➢...

  • Page 65: Service Door

    11.2 Service Door The service door should be kept close all the time. Access through the service door is for authorized personnel and trained technicians only. The service door must be closed after entrance into the service area to minimize the intrusion of moisture into the system.
  • Page 66 During access through the service door check the seal of the door for ice formation. Any ice formation should be checked regarding proper sealing of the service door. CAUTION ! ➢ Use the door handle to open the service door ➢...

  • Page 67: Cassettes

    Cassettes 12.1 Buffer Cassettes Cassettes allow simple and comfortable loading and unloading of storage samples and can be prepared outside the climate chamber. Once prepared, the samples can be quickly transferred into the climate chamber of the Kiwi unit. There is a wide variety of cassette types available. Make sure that you work with the proper cassette size that matches the type of plates you are using.
  • Page 68 The carousel must be kept clean as particles may cause the cassette to tilt. Do not place cassettes on the floor as they may pick-up dust etc. Always store cassettes inside the climate chamber or on clean surfaces. Use the cassette handle for transport of the cassettes. When lifting the cassette by its handle it will tilt backward slightly in order to prevent plates from shifting to the front.
  • Page 69 Cassette Handle Cassette Cassette Back Carousel The cassettes are secured by alignment rails to the carousel. The cassettes may be tilted slightly backwards (towards the front opening) for removal. In order to load a cassette align the back of the stacker base plate to the cassette alignment rail. Push the cassette forward until it stands vertically.

  • Page 70: Storage Cassettes

    CAUTION ! ➢ Make sure that ALL plates are pushed to the back of the cassette. Plates jutting out the front side of the cassette may cause collision with the handler shovel. ➢ Lift cassettes by their cassette handles only ➢...
  • Page 71 To re install cassettes the have to be lowered from the service area down into the storage area. The cassette needs to be lined up with the openings in the trolleys. The hooks on the back of the cassette need to match with the openings. As this is matched up the cassette needs to be pushed down until it is all the way down.

  • Page 72: Power On

    Power On 13.1 Power-On Interface The instruments power is activated by the main switch. The instrument is turned on by pressing the power switch located at the front of the instrument. After power- on the climate portion of the instrument is activated automatically. An alarm will sound.

  • Page 73: Power-On Stc Store

    13.2 Power-On STC Store The instruments power is activated by the main switch. The instrument is turned on by pressing the power switch located at the front of the instrument. The climate portion of the instrument is activated Independently. An alarm will sound. If the green light of the power switch does not turn on, check the fuse in the mains supply.

  • Page 74: Climate Settings

    Climate Settings 14.1 Temperature Settings System Temperature is pre-set. Temperature should only be changed by a qualified system administrator or LiCONiC engineer. 14.2 Humidity Settings Humidity is kept as low as possible and is not adjustable. BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 75: Cooling Unit Operation

    Cooling Unit Operation 15.1 Switch on Cooling STC ULT The cooling units should stay switched on all the time. Initial power up of cooling should be performed with switched off handling of store. All cables should be connected before start up. To switch on the cooling unit the main power switch needs to be turned into the position stating ON.
  • Page 76 Pressure CAUTION ! ➢ Do not disconnect any cables, except a LiCONiC engineer did advise to do ➢ All cooling units have to be permanently switched on. ➢ The key switch has to stay in automatic position, for normal operation.

  • Page 77: Recovery After Backup Activation

    CAUTION ! ➢ Ensure normal conditions being restored to operate the main cooling ➢ Ask for assistance from a LiCONiC engineer in case of insecurity about normal conditions and performing the recovery procedure. ➢ Observe cooling after recovery. Contact immediately a LiCONiC engineer in case of repeated stop of cooling after recovery.

  • Page 78: Service Operation Of Backup Cooling

    CAUTION ! ➢ Ensure normal conditions being restored to operate the main cooling ➢ Ask for assistance from a LiCONiC engineer in case of insecurity about normal conditions and performing the recovery procedure. ➢ Observe cooling after recovery. Contact immediately a LiCONiC engineer in case of repeated stop of cooling after recovery.

  • Page 79: Barcode Reader

    Barcode Reader 16.1 1D Reader for racks and plates The Barcode reader for plate/rack identification is mounted onto the handling mechanism. The Barcodes must be placed on the shorter side of the plates and must face towards the open side of the cassette. The barcodes should be parallel to the plate’s lower edge.

  • Page 80: The Robot Gate

    16.3 The Robot Gate The robot gate is located on the side of the Interface unit. Through the robot gate the storage samples are transported by the handler. The robot gate has the same sealing system as the front door. Because of the frequent accessing through the gate, special care must be taken with the sealing performance of the gate.

  • Page 81: Routine Safety Checks

    Routine Safety Checks Carefully read all safety instructions before operating the instrument. Be sure that you fully understand their content. Although the KIWI STORE is intended to be operated as a remote-controlled system, there still are some manual interactions required for operation. Apart from these operations there are also some very important safety checks the operator should be familiar with.

  • Page 82: Software

    In an integrated environment such as a connection to a LIMS system the pick orders are sent through a direct connection to the Liconic System. These files are only used in a stand alone configuration.

  • Page 83: Complex Order File

    18.1.2 Complex order file In case of the complex order file, the file consists of a parameter list. This file can be passed onto the system as a CSV (Comma Separated Values) file. The file can be populated manually by a user or exported from Excel© or a database too. Picture 4 below shows an example of a complex order file.

  • Page 84: Import - Export Interface

    Import – Export Interface 18.2 The Liconic Import and Export interface is used to create and execute operations with the result to load samples to the system or unload them from the system. In stand-alone configuration this can be used to introduce samples to the system, start pick orders and unload samples from the system.

  • Page 85: Import

    18.2.1 Import The import view provides an overview of all registered jobs for loading plates into the system. One import job can consist of several tasks. The application allows to create import jobs with tasks. A listing of the possible tasks is provided at the chapter BiO.Li.X! STC V1.0 RKi, 19.08.2022...
  • Page 86 Create Import. Picture 6: Import View with Rack details Selecting the import job, provides a detailed view of additional information in the “Properties” view (See Picture 6: Import View with Rack details). Information such as barcode, lab ware type and target storage partition are displayed. By right clicking on the import job it is possible to delete a created job.
  • Page 87 Picture 8: Detail Information on Task 1 By selecting an individual task of an import job additional information and properties are shown. The shown information depends on the current state each task is in. Picture 9: Detail Information on Task 1 In the “History”...
  • Page 88 Create Import The Import – Export Interface does allow to create import jobs. To do so the menu entry “Tools” is selected and in there the entry “Import Plate” is selected. This will call a dialogue to enter details and select the properties for the import. Picture 10: Tools Menu Import Picture 11: Import Plate Dialogue The import dialogue will require to enter a barcode of the plate going to be loaded...
  • Page 89 The “Type” menu allows the selection of the lab ware type. The menu will only provide the lab ware types the system is configured for. The lab ware type can not be changed once the plate has been introduced into the system. If the lab ware type has be set wrongly the import has to be deleted and created newly.
  • Page 90 Trigger Import To trigger an import either the door icon or the transfer station icon has to be pressed. The door icon will show a dialogue and guide through the steps of loading samples through the user door into the buffer cassettes. Picture 12: Icons to trigger Import The dialogue will tell when you need to open the user door.

  • Page 91: Export

    18.2.2 Export The export view provides an overview of all registered jobs for collecting individual samples and plates to be unloaded. One export job can consist of several tasks. The application allows to create export jobs. Create Export Selecting in the Tools menu the entry “Pick Job” will open up the Windows file dialogue.
  • Page 92 Picture 15: Export Task Detail 1 If the actual pick task is selected the detail view varies according the state the pick task is in. In the created state only the list of tubes is shown. During the running state tubes vanish according them to be moved within the progress of the pick task. In the done state all tubes are listed with their target position and the status.
  • Page 93 By right clicking onto the pick task the context menu is provided. This menu is active in the states created, running and error. The “Retry” and the “Continue” functions are solely used in the error status. Is the error state caused by a hardware error this needs to be resolved in order to continue operating the system.

  • Page 94: Exception Plates

    Picture 19: Unload plate from system The second possibility requires to select in the context menu the item “Export Rack to Buffer” the plate will be moved into the buffer area inside the interface unit. To remove the rack the door icon in the interface has to be clicked. Follow the dialogues.

  • Page 95: Connections

    18.2.4 Connections In the connection menu the connection to the scheduler can be reestablished. Also the “Update content” can manually be triggered. This function is used if an expected entry in the Import or Export view is not present. Update content will recheck in the database if there are new entries not yet visualized.

  • Page 96: Plateexplorer

    18.3 PlateExplorer The PlateExplorer is the more sophisticated administrational access possibility to the Storage system. It allows to manage the system and use some functions manually. The functions accessible may vary according to user permissions. Administrator user have the least restrictions. The PlateExplorer is a network based application and can run therefore on a remote computer over the network.

  • Page 97: General Functionalities

    18.3.1 General Functionalities In this chapter the functionality accessible to the administrator and the normal user are described. There is only one difference between user and administrator. Whilst the user has only access to the assigned area, the administrator has access to the full store.

  • Page 98: Layout Of The Plateexplorer

    18.3.2 Layout of the PlateExplorer The main window of the PlateExplorer is subdivided into the Menu bar, the contents tree on the left and the detailed information view on the right (see Picture 25). Picture 25: Main screen of the PlateExplorer BiO.Li.X! STC V1.0 RKi, 19.08.2022...
  • Page 99 The Menu Bar The menu bar of the PlateExplorer covers four main entries. The “File”-menu item offers the user to “Exit” the program. Picture 26: File Menu Entry The “View” options enable the user to define the way to look at the items being displayed in the PlateExplorer’s Detail View on the right.
  • Page 100 The “Service” allows access to the Service functions. Currently it contains only the entry to reestablish the connection to the server. Picture 28: Service Menu Entry (to be checked) The “About” window will show information on the running PlateExplorer software. Picture 29: About Menu Entry BiO.Li.X! STC V1.0...
  • Page 101 Tree View The tree view is located on the left side of the PlateExplorer window. All accessible positions plates are held are represented in the tree view. Transfer positions such as internal upper and bottom position, 2D Reader, Tube handling source/target and cassette positions can be accessed.
  • Page 102 Picture 31: Tree View Overview BiO.Li.X! STC V1.0 RKi, 19.08.2022...
  • Page 103 The Detail Information Screen The detail information screen on the right of the PlateExplorer shows the user all properties of the item selected within the tree view on the left. Its functionality can mostly be accessed with the help of the right-click action menus. The Partition management will be described in the corresponding chapter of this manual.
  • Page 104 Alternative to the detail view a location view can be selected. It is only available on plate level. A visualization of the plate with its physical positions is presented. The positions are represented as grey if they are empty or as green if a tube is present. A red position with a question mark indicates a tube present with an unreadable 2D code.

  • Page 105: User Management And Alarm Notification

    18.3.3 User Management and Alarm Notification The Administrator mode allows the creation, modification and deletion of users and their rights. In the picture below (Picture 34) the “User Manager” is shown. All users accessing to the system have to be created with this tool, even users accessing only through the Web-Access.
  • Page 106 To edit a user the desired user is selected from the list on the right and the “Edit” button pressed. The fields on the left side will get editable. Change the information and press the “Save” button to store the changes made. When finished, press “Close”...

  • Page 107: Partitions Tool

    18.3.4 Partitions Tool Depending on the use of the system different partitions can be created. Partitions are virtual subdivisions and can be used to split the storage capacity for different uses, user groups or experiments. To launch the partition tool mark the system unit with a left click, then right click and select “Partition”...
  • Page 108 Picture 38: Right Click Menu Table Existing partitions can easily be manipulated. Just right click into the graphic or the table and select the option. The “Add Partition” in the graphic is only available if unassigned cassettes (represented in grey) are available. (Picture 39) Picture 39: Add Partition Unassigned Cassette BiO.Li.X! STC V1.0...
  • Page 109 Picture 40: Add Partition Dialogue BiO.Li.X! STC V1.0 RKi, 19.08.2022...
  • Page 110 Unassigned cassettes can be used to create a new partition (Picture 41) or assign them to an existing partition (Picture 42). Adding cassettes to existing partition will be represented by the same coloring. In the table the cassettes will be displayed in order only the partition name will show their association.
  • Page 111 Picture 43: Dialogue Rename If cassettes are “scattered” meaning a partition consists of cassettes not being next to each other the partition segments have to be deleted individually (Picture 44). Picture 44: Deleted Partition A BiO.Li.X! STC V1.0 RKi, 19.08.2022...
  • Page 112 Also partitions may be resized (Picture 45). The partitions may be made larger if unassigned cassettes are available or made smaller if they consist of more than one cassette. Resizing is not available if the minimal partition size of one cassette is present and no unassigned cassettes next to the partition available (Picture 46).

  • Page 113: Right-Click Action Menus In The Tree View

    18.3.5 Right-Click Action Menus in the Tree View The right-click action menus are the most powerful tool within the PlateExplorer. They cover most of the commands and their content is depending on where they get activated. Right-Click a “Unit” When right-clicking a unit, a sub menu appears as shown in Picture 47 below. Picture 47: Right Click Menu Unit “Initialize”...
  • Page 114 Picture 48: Unit properties Right-Click a “Partition” When right-clicking a partition, a sub menu with several options appears. Picture 49: Right Click Menu Partition “Inventory” starts a 1D barcode inventory on the selected partition. “Search” lets the user search within the partition for key words such a plate barcode, tube code or fragments of them.
  • Page 115 Right-Click a “Cassette” When right-clicking a cassette, there are two options to choose from: Picture 50: Right Click Menu Cassette “Properties” will show the usage graph of the clicked cassette and a check box to block the complete cassette for administrative reasons. BiO.Li.X! STC V1.0 RKi, 19.08.2022...
  • Page 116 Right-Click a “Level” When right-clicking a level, several options will appear: Picture 51: Right Click Menu Level (to be checked) “Cut” and “Paste” will enable the user to move plates within the system as described in 1.3.1. under “Using Cut&Paste”. “Load”...
  • Page 117 The “Properties” of a rack in a level allows under the tab “Plate” to set the PlateID, add some note, see location information of the chosen Level. Furthermore, the plate type can be removed or the plate type changed. Changes of the plate type are only possible with certain limitations.
  • Page 118 Under the tab “Tubes” it is possible to set the tube type if not yet set and load content from an XML file. Furthermore, the content of the plate can be saved as a file. Some general information about the tube configuration and the content of the plate is shown such as the tube parameters, number of tubes and free locations.

  • Page 119: History

    18.3.6 History The “History” tab in the level and plate properties allows to access the history data for the respective. The history contains the information which user did conduct, the respective Event at which date and what Barcode and User ID was involved. Picture 54: Properties History Level If no plate is present when selecting a level only the history of the respective level is available.
  • Page 120 Is a plate present on the selected level, the history of this plate is available. Similar to the level history the User manipulating the plate, the date, the performed Event and the location of the plate are displayed. Picture 55: Properties History Plate BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 121: Right-Click Menu On Tubes At Tube Handling

    18.3.7 Right-Click Menu on Tubes at Tube Handling The right-click menu on the tube handling unit covers the following items: “Cut” and “Paste” enable the user to manually move tubes from plate to plate on the device. “Check Presence” will work only depending on the model of the tube handling. If integrated, the function checks if a tube exists on the clicked location within the rack.

  • Page 122: Right-Click Action Menu On 2D Rack Reader

    18.3.8 Right-Click Action Menu on 2D Rack Reader The right-click menu on the 2D Rack Reader allows to select the following items: “Cut” and “Paste” enable the user to manually move plates and racks from and to the reader. “Check Presence” will check if a plate or rack is present on the reader. “Property”...
  • Page 123 Selecting the “Scan” option will trigger a scanning process when a plate is present on the scanner. An additional Window is opened showing the result of the scan. This window allows to re-scan or safe the scan results into the database. It has two display options one shows the locations of the tubes in a visual representation and the other one as a list.

  • Page 124: Job Manager

    18.4 Job Manager The JobManager Web based interface allows to manipulate jobs. The different coloring of the jobs are indicating their status and manipulation can be performed upon them such as Cancel, Continue, Retry, Delete. The available functions are provided by each job/task. If a job/task is in error it will offer the options Continue, Retry and Cancel if they are possible.
  • Page 125 Picture 62: JobManager Main Page Jobs in the different states allow for different manipulations. To delete a job from the queue it has to be first cancelled. The cancelation of a job can be easily performed by pressing the “X” within the circle at the right of each job. Only after the cancelation the delete icon in the shape of a trash bin becomes available.
  • Page 126 Picture 63: JobManager Task Options Picture 64: JobManager Task Details BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 127: Climate Reporting

    18.5 Climate Reporting The climate reporting interface is used to extract climate data from the database. The historic and current climate values can be accessed, displayed and saved for further use. To access the Climate Reporting user interface, it is required to log in. The access to this may be restricted, depending on the user access rights Picture 65: Climate Reporting Log In The main page after the log in will show an overview of all device which have...
  • Page 128 To access the detail view for a device, the device is selected and clicked. Afterward a graph view is presented. Picture 67: Climate Reporting Device Selection The graph view allows to view current and historic data. The displayed data can be selected by device.
  • Page 129 From the graph view it is possible to extract the climate data. The graphs can be saved as picture or directly printed. The climate data can also be exported as a CSV file for further use. Picture 69: Climate Reporting Save BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 130: Software Tools

    This terminal should only be used by trained personnel or under the supervision of a Liconic engineer. If there are any uncertainty in the use of the terminal please contact your local engineer or the Liconic service organization.

  • Page 131: Trouble Shooting

    Trouble shooting Troubleshooting The following chapter does give assistance to the customer to fix some errors which eventually could appear. 20.1 Basic Errors The following table shows some basic errors of the Kiwi Stores which can be fixed by the customer. If the steps below aren’t successful, please contact an authorized service person.

  • Page 132: Error Listing

    (column $Hex), for manual Read out the decimal number (column #Dec) may be helpful. Liconic provides an error converter tool. The errors may also be manually translated it the tool is unavailable. Therefore the following procedure may be used:...

  • Page 133: Tubepicker

    20.2.2 TubePicker #Dec $Hex Description General time out; Operation took longer than 15 Minutes General time out; Time out after previus time out; Operation longer than 5 Minutes Init time out; Initialization has taken to long Tube Trace Error; Tube has not been taken into or moved out of gripper as expected Wrong Tube Y;...

  • Page 134: Handling Errors

    Should any mechanical resistance be observed while the robotics are moving, reset the system immediately and ask a trained engineer for assistance. Should non of the procedures be of help contact a Liconic trained engineer for further support. CAUTION ! ➢...

  • Page 135: Gerneral

    20.3.1 Gerneral BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 136: Free Shovel Procedure

    20.3.2 Free Shovel Procedure BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 137: Init Error Analysis

    20.3.3 Init Error Analysis BiO.Li.X! STC V1.0 RKi, 19.08.2022...

  • Page 138: Technical Data

    Technical Data Technical Data 21.1 Mechanics • Cassettes Depending on system configuration • Levels Depending on used lab ware • Position drives Stepper Motor, bipolar, micro-stepping mode • Shovel drive DC-Motor • Gate Linear movement, heated • Noise <82dBA / 1m •...

  • Page 139: Cooling

    For detailed installation requirements refer to the section installation. 21.6 Overall Dimensions System dimensions do depend on the configuration. Dimension for specific systems may be retrieved from LiCONiC according to the needs and room constraints. 21.7 Weights System weights do depend on the configuration. Weights for specific systems may be retrieved from LiCONiC according to the needs and room constraints.

  • Page 140: Appendix

    Appendix BiO.Li.X! STC V1.0 RKi, 19.08.2022...

This manual is also suitable for:

Biolix! stc7k0 dfBiolix! stc16k0 ultBiolix! stc18k5 ultBiolix! stc70k5 ultBiolix! stc101k ultBiolix! stc118k ult

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