Table of Contents
Advertisement
Quick Links
Advertisement
Table of Contents
Related Manuals for Oxford Optronix OXYFLO
Summary of Contents for Oxford Optronix OXYFLO
- Page 1 USER MANUAL...
- Page 2 Banbury Business Park Adderbury OX17 3SN United Kingdom t: +44 (0)1235 821 803 Sales www.oxford-optronix.com sales@oxford-optronix.com Support www.oxford-optronix.com/support/oxylite-support support@oxford-optronix.com OxyFlo™ and OxyLite™ are registered trademarks of Oxford Optronix Ltd. © Oxford Optronix Ltd. 2023. All rights reserved. Revision 1.4 | October 2023...
-
Page 3: Table Of Contents
Regulatory Compliance ..................... 5 Laser Safety ....................... 5 OxyFlo Symbols ......................5 Definitions ......................... 6 Summary of Warnings for the OxyFlo Monitor ............6 Summary of Cautions for OxyFlo ................7 1.10 Summary of Cautions for OxyFlo Probes ..............7 1.11 Summary of Cautions for Probe Calibration .............. - Page 4 Table 3: Display messages ...................... 19 Table 4: Calibration error codes ..................... 21 Table 5: Analogue output unit conversion ................24 Table 6: Diagnostic analogue output voltages ................ 24 Table 7: Technical specifications for OxyFlo ................33 Revision 1.4 | October 2023...
-
Page 5: Safety Information
In common with all LDF devices, quantitative measurements of tissue blood flow in absolute units (e.g. ml/min/g of tissue) are not possible with the OxyFlo. The OxyFlo has been specifically developed for use with the OxyLite, a fibre optic tissue pO and temperature monitor. The combination of these two fibre optic measurement systems provides simultaneous tissue blood flow and oxygenation data. -
Page 6: Regulatory Compliance
Never apply an OxyFlo probe directly to the eye. The laser exposure may cause permanent damage to the retina. WARNING OxyFlo is classified as a Class 1 Laser Product in accordance with the European Standard EN 60825-1:2014 and 21 CFR 1040.10 and 1040.11. Class 1 Laser Product OxyFlo incorporates semiconductor laser diode devices operating in continuous mode and emitting invisible laser radiation at a nominal operating wavelength of 785nm. -
Page 7: Definitions
To avoid the risk of electric shock or shorts, do not spray, pour or spill any liquid in or on the OxyFlo. WARNING Never apply an OxyFlo probe directly to the eye. The laser exposure may cause permanent damage to the retina. WARNING... -
Page 8: Summary Of Cautions For Oxyflo
OxyFlo User Manual Summary of Cautions for OxyFlo DO NOT attempt to operate the OxyFlo in the vicinity of imaging or therapeutic equipment that emits ionising radiation or produces a strong magnetic field as the performance of the monitor may be affected. -
Page 9: Summary Of Cautions For Probe Calibration
CAUTION Do not dilute the motility standard. CAUTION It is important that all probes to be used with any one OxyFlo monitor have different probe identification numbers to prevent possible probe calibration errors. Please contact technical support for advice. CAUTION... -
Page 10: Introduction
NTRODUCTION General description The OxyFlo is a microvascular blood flow monitor that is capable of monitoring red blood cell (erythrocyte) perfusion in the microcirculation of a tissue. The monitor uses a technique referred to as Laser Doppler Flowmetry (LDF), an established and reliable method for the measurement of blood perfusion in microvascular research. -
Page 11: Laser Doppler Flowmetry And The Oxyflo
Measurement parameters generated by the OxyFlo The blood perfusion unit (BPU) The primary function of the OxyFlo is to produce a tissue blood flow output signal that is proportional to the red blood cell perfusion (or flux) in the area of tissue being investigated. - Page 12 For the OxyFlo, tissue blood flow is indicated in relative units called Blood Perfusion Units (BPU). All OxyFlo monitors have been calibrated with a constant, known motility standard so that, for a given blood flow situation, all OxyFlo probes will read the same value of blood flow expressed in BPU.
-
Page 13: The Oxyflo Monitor
OxyFlo User Manual The OxyFlo Monitor Figure 1: OxyFlo front view 1. Power-on indicator light 2. Alphanumeric OLED display 3. Probe connector Revision 1.4 | October 2023... -
Page 14: Oxyflo Probes
The fibres terminate at one end of the probe in the probe head (of variable design, depending on probe type) and at the other end in a connector plug that attaches to the OxyFlo. The connector plug is colour-coded with a red band. -
Page 15: Figure 3: Probe Presentation
Probe Presentation OxyFlo probes consist of a pair of optical fibres used to direct weak laser light to and from the probe head. The fibres terminate at one end in the probe head (MSP300NX suturable surface probe type depicted here) and, at the other end, in a connector plug that attaches to the OxyFlo (colour-coded with a red band). -
Page 16: Accessories
CAUTION Avoid using OxyFlo probes under strong (e.g. surgical) lights. CAUTION Accessories The following accessories are available from Oxford Optronix Ltd. for use with the OxyFlo Product Code Product Description CAL KIT Calibration kit for LDF probes and MSFD NX adapter MSP140AR Double-sided adhesive rings for surface LDF probes. -
Page 17: Monitor Setup And Use
2. Ensure that the power on/off switch at the rear of the OxyFlo is in the OFF (0) position. 3. Plug the IEC power cable into the IEC mains inlet at the rear of the OxyFlo and the plug end of the IEC power cable into a wall mains supply. -
Page 18: Display Messages
Display Messages The OxyFlo front panel displays blood flow and backscatter measurements when a probe is connected and in use. Other messages, including error messages are also displayed to the user. A list of messages and their meaning is provided below:... - Page 19 OxyFlo User Manual There is no probe connected to the OxyFlo, but the monitor has completed its boot sequence and is ready for use. Analogue output during No Probe this time is -2.5V (-50% scale). Probe ID=nn When a probe is connected the probe ID is briefly displayed.
-
Page 20: Probe Calibration
Table 3: Display messages Probe Calibration The OxyFlo monitor is designed to automatically recognise and apply the correct calibration coefficient when a probe is connected. Probes purchased with a monitor will be calibrated at the factory. Since the calibration data... -
Page 21: Figure 5: Preparing A Probe For Calibration
The probe should be supported in such a way that it does not swing or move whilst in the solution. 4. Connect the probe that you wish to calibrate to the OxyFlo. NOTE: If the probe has not previously been calibrated the display will show a ‘Calibrate Probe’... -
Page 22: Table 4: Calibration Error Codes
OxyFlo User Manual displayed. This is followed by the message ‘Calibration – CAUTION’ while the calibration is in progress. IMPORTANT: This 20 - 30 second period is where any vibration or movement will cause the calibration procedure to fail. If the calibration is successful, the message ‘Calibration – Cal OK’ is displayed accompanied by an audible double ‘beep’. -
Page 23: Placement Of Probes
Placement of Probes Please note that additional guidelines for the use of probes in a variety of tissue monitoring applications are maintained on our dedicated OxyFlo support site: https://www.oxford-optronix.com/support/oxyflo-support IMPORTANT: In all cases direct ‘occlusive’ pressure on the tissue under investigation and tissue or probe movement must be avoided as far as possible. -
Page 24: Digital (Usb) Data Output
Alternatively the Oxford Optronix Device Enabler is available for download from the ‘Downloads’ section of the ADInstruments website. Dedicated instructions for setting up LabChart Pro for recording from OxyFlo monitors can be found on our support site (https://www.oxford-optronix.com/support/oxyflo-support). Revision 1.4 | October 2023... -
Page 25: Analogue Data Outputs
‘OLO-BNC’) provide compatibility with most data acquisition systems. NOTE: While the OxyFlo displays readings up to 9999 BPU, the analogue output range is limited to a max of 5000 BPU. This is a trade-off that provides improved resolution in the 0- 5000 BPU range, which is sufficient for almost all scenarios likely to be encountered. -
Page 26: Care Of Oxy Flo
The integrity of OxyFlo probes may be checked by holding the probe end to a source of bright light and inspecting the connector end for two spots equally intense light from the pins within the connector (refer to section 5.2). -
Page 27: Cleaning, Disinfection And Sterilization Of Probes
Avoid immersing the probe connector in any cleaning solution. CAUTION Disinfection OxyFlo probes can be disinfected by immersion of the probe end and cable in either 2% gluteraldehyde or in 70% alcohol (industrial methylated spirit, IMS or isopropyl alcohol IPA) in water. -
Page 28: Disposal Of Probes
The effectiveness of ETO gas, radiation or plasma methods for probe sterilization has not been validated. CAUTION It is the responsibility of the user to validate the sterility of OxyFlo probes after sterilisation. CAUTION DO NOT attempt to autoclave, pressure sterilise, or expose to radiation, any part of the monitor. -
Page 29: Troubleshooting And Maintenance
AINTENANCE Troubleshooting If you experience a problem using the OxyFlo that you are unable to correct by following the suggestions below or by reconnecting a probe and/or turning off and turning back on the monitor, please contact Oxford Optronix technical support (see p2 of this document). - Page 30 The OxyFlo may not therefore be suited to the non-continuous or repeated assessment of changes in tissue blood flow over chronic time periods. The strengths of the laser-Doppler technique lie in observing continuous, acute changes in blood flow relative to a baseline (control).
-
Page 31: The Meaning Of Zero Or Negative Bpu Values
‘Temp out of Range’ will appear on the display. If this occurs check that the fan at the rear of the OxyFlo is not obstructed and/or move the instrument to a cooler location. Analogue outputs will continue but the readings will not appear on the display. -
Page 32: Simple Probe Integrity Check
OxyFlo User Manual Simple Probe Integrity Check The integrity of the optical fibres within OxyFlo probes can be confirmed by holding the probe end to a source of bright diffuse light (e.g. a ceiling light) whilst visually inspecting the connector end. Two bright spots of light of equal intensity should be visible from the two pins within the connector. -
Page 33: Returning The Oxyflo Monitor
Declaration form MUST be obtained prior to shipping the equipment. Pack the OxyFlo in its original shipping carton where available. If the original carton is not available, pack the OxyFlo in a suitably sized STURDY cardboard box ensuring that it is surrounded on ALL sides by at least 10 cm (4”) of tightly packed polystyrene chips, bubble... -
Page 34: Technical Specifications
200Hz Measurement averaging 200ms (Flow); 200ms (Backscatter), rolling Display update interval 2s (5s rolling averaged) Probe identification Automatic; monitor stores one-time calibration Factory or user-calibrated using Oxford Optronix motility Probe calibration standard Probe shelf-life Unlimited Zeroing Automatic, controlled Table 7: Technical specifications for OxyFlo Specifications subject to change without notice. -
Page 35: Warranty
User Instructions for a period of 24 months from the date of purchase. Oxford Optronix Ltd’s sole obligation shall be to repair or to replace at Oxford Optronix’ option, FOB its factory, without charge, any part(s) that prove defective within the warranty period.
Need help?
Do you have a question about the OXYFLO and is the answer not in the manual?
Questions and answers