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Applikon ADI 1075 Installation/Hardware Manual

Pilot system
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Summary of Contents for Applikon ADI 1075

  • Page 2 SYMBOLS ADI 1075 Pilot System December 2002 SYMBOLS The following symbols are used on the equipment and in this manual: Warning; refer to this manual. Caution; electrical shock hazard. Important note; read the instructions carefully. Protective conductor terminal. Applikon Dependable Instruments...
  • Page 3 ADI 1075 Pilot System December 2002 SAFETY CLASS I APPARATUS This apparatus has been designed in accordance with IEC1010-1 "Safety Requirements for Electrical Equipment for Measurement, Control and Laboratory Use", and has been supplied in a safe condition. The installation manual...

  • Page 4: Eu Declaration Of Conformity

    CE CONFORMITY EU DECLARATION OF CONFORMITY The company Applikon Dependable Instruments B.V., Schiedam, The Netherlands, hereby certifies that the instrument: ADI 1075 PILOT SYSTEM meets the requirements of the EU Directives 89/336/EEC (Electromagnetic Compatibility) and 73/23/EEC (Low Voltage). SOURCE OF THE SPECIFICATIONS: 89/336/EEC: EN 50081-2 (1993) EMC Generic emission standard.
  • Page 5 INSTALLATION AND HARDWARE MANUAL GENERAL ADI 1075 Pilot System December 2002 CHAPTER 1 GENERAL The Applikon range of controlled in situ sterilizable Pilot Systems can be represented by the following image: Where: A = the bioreactor, the frame, t h e...

  • Page 6: Basic Unit

    PILOT SYSTEM BASIC UNIT 2.1 INTRODUCTION: The ADI 1075 Pilot System is an actuator console that is used in combination with In Situ Sterilizable ADI bioreactors and an ADI 1060 or an ADI 1030 Bio Controller. It supports gas flow regulation (with rotameters or mass flow controllers), head plate lift control (optional), stirrer speed control, level control, temperature control (with hot and cold water or steam) and liquid addition with pumps.

  • Page 7: Front View

    BASIC UNIT ADI 1075 Pilot System December 2002 2.2 FRONT VIEW: Front view of the ADI 1075 Pilot System (without frame and wet part) A = Power section B = Gas supply section C = Lift control (optional) D = Stirrer speed control...

  • Page 8: Right Hand Side View

    D = Connections for Jacket E = Position for Bioreactor The ADI 1075 Pilot System Cabinet is mounted on a frame with wheels. The dimension of the frame depends on the size of the bioreactor (graphical image shows the frame for a 20 -...

  • Page 9: Rear View

    E = Mains cable gland F = Wet part connections bulkhead The rear panel of the ADI 1075 Pilot System can be removed in order to replace fuses (refer to chapter 2.5: Installation); turn both pawl latches counter clockwise to unlock..
  • Page 10 INSTALLATION AND HARDWARE MANUAL BASIC UNIT ADI 1075 Pilot System December 2002 2.5 INSTALLATION: PHYSICAL DIMENSIONS: For physical dimensions (H x W x D) refer to the drawings in chapter 9. WATER & STEAM SUPPLY: Supply of water and steam must be connected at the rear of the frame; see pictures below:...
  • Page 11 The connections (quick connectors) for compressed air and gasses for process control (air, oxygen, nitrogen and carbon dioxide) are located at the rear (right hand lower corner) of the ADI 1075 Pilot System cabinet. Tube diameter (OD) for compressed air:...
  • Page 12 ADI 1075 Pilot System December 2002 PNEUMATIC & ELECTRIC CONNECTIONS FROM CABINET: The front of the ADI 1075 Pilot System Cabinet has a number of pneumatic and electric connections; see picture below: The pneumatic connections operate the actuators of the Wet Part Valves: V-2.04 = circulation valve...
  • Page 13 ADI 1075 Pilot System December 2002 MAINS SUPPLY: 400V3~ or 200V3~ High Voltage Current The ADI 1075 Pilot System is supplied with a voltage selection package; this package is available in two voltage versions: Z310750020 : Pilot System voltage selection package 115 Vac, Z310750030 : Pilot System voltage selection package 230 Vac.
  • Page 14 INSTALLATION AND HARDWARE MANUAL BASIC UNIT ADI 1075 Pilot System December 2002 Fuses: Internally - behind the rear panel - a number of fuses can be found. See the image below: Fuses F21 through F23 are used for the applied stirrer motor and are described in the manual of the ADI 1032 stirrer speed controller.
  • Page 15 (the image shows the internal power supply board that is located at the transformer at the bottom of the ADI 1075 cabinet): F1 = Main Fuse, F2 = Fuse circuit 24 Vdc, F3 = Fuse circuit 12 Vac, F4 = Fuse circuit 230 Vac.

  • Page 16: Power Section

    ADI 1075 Pilot System December 2002 2.6 POWER SECTION: The image of the power section of the ADI 1075 Pilot System is presented below: Where: A = Power On Indication (green LED), B = Power On Switch, C = Emergency Stop Button.

  • Page 17: Environmental Conditions

    - Transient over voltages according to INSTALLATION CATEGORIES II, - POLLUTION DEGREE 2 in accordance with IEC 664, - P-max = 6900 VA. 2.8 CLEANING INSTRUCTIONS: The ADI 1075 Pilot System (cabinet and frame) may be cleaned with a moist tissue in combination with a non-abrasive cleaner. 2-12...

  • Page 18: Gas Supply

    For Mass Flow Controllers The different gasses are internally connected to a manifold. In this manifold the gasses are mixed and directed to the gas supply bulkhead connector at the front of the ADI 1075 Pilot System. Available rotameter assemblies: Z3RM000005 Rotameter assembly 2.5 - 25 ml/min,...
  • Page 19 INSTALLATION AND HARDWARE MANUAL GAS SUPPLY ADI 1075 Pilot System December 2002 Z3RM000060 Rotameter assembly 0.5 - 5.0 l/min, Z3RM000070 Rotameter assembly 1.0 - 10 l/min, Z3RM000080 Rotameter assembly 2.3 - 23 l/min, Z3RM000090 Rotameter assembly 4.3 - 43 l/min, Z3RM000100 Rotameter assembly 6.0 - 60 l/min.
  • Page 20 - The valve module contains a non-return valve which means that other gasses (or steam) never can flow back into the supply system! Mass Flow Controllers are available in the following versions: Z3MFC0033 Mass Flow Controller Max. 30 l/min 230Vac ADI 1075, Z3MFC0036 Mass Flow Controller Max. 30 l/min 115Vac ADI 1075, Z3MFC0100 Mass Flow Controller Max.
  • Page 21 INSTALLATION AND HARDWARE MANUAL LIFT CONTROL ADI 1075 Pilot System December 2002 CHAPTER 4 LIFT CONTROL (OPTIONAL) In case electrical head plate lifting is applied, the lift control section contains a key switch for operation and two LED indicators (operation is enabled, lift motor is active).

  • Page 22: Temperature Control

    INSTALLATION AND HARDWARE MANUAL TEMPERATURE CONTROL ADI 1075 Pilot System December 2002 CHAPTER 5 TEMPERATURE CONTROL 5.1 TEMPERATURE CONTROL SECTION: A = Sterilization indication B = Cooling indication C = Illumination push button D = Tumbler switch E = Fermentation indication...
  • Page 23 Consequently the sample and bottom valve can be sterilized independently. All other valves are closed. Note: - When the main supply of the ADI 1075 Pilot System is switched off (or the Emergency Stop button is pressed), steam supply valve V-2.13 is closed.
  • Page 24 C. After pre-heating the hydrophobic filter, steam can be directed to the bioreactor itself. For more information about sterilization, refer to the operator manual of the ADI 1075 Pilot System. During the sterilization process, the temperature control section must not be switched off! Switching off the temperature control section may result in large pressure differences between jacket and environment.
  • Page 25 INSTALLATION AND HARDWARE MANUAL TEMPERATURE CONTROL ADI 1075 Pilot System December 2002 After completing the sterilization interval, the steam is closed and water is circulated through the jacket: Steam to sample & bottom valve Steam Supply Steam to air inlet filter V-2.05...
  • Page 26 INSTALLATION AND HARDWARE MANUAL TEMPERATURE CONTROL ADI 1075 Pilot System December 2002 During fermentation, the valves in the wet part are switched in such a way that recirculation and heating is possible: Steam to sample & bottom valve Steam Supply Steam to air inlet filter V-10.05...
  • Page 27 CHAPTER 6 STIRRER SPEED CONTROL 6.1 STIRRER SPEED CONTROL: The ADI 1075 Bio Console can be equipped with four different stirrer speed controllers for a range of stirrer motors (see list next page). Stirrer speed control section: A = Power / overload indication...
  • Page 28 S "Remote" = stirrer speed is controlled by the ADI 1010 Bio Controller. Note: The motor fuses are located behind the rear panel of the ADI 1075 Pilot System; refer to chapter 2.5 of this manual. Ordering information for applicable hardware:...

  • Page 29: Level Control

    CHAPTER 7 LEVEL CONTROL The Level Control option of the ADI 1075 Pilot System can be used to activate a pump on liquid contact with the level sensor; this option is used for both foam control and level control. Level control section:...
  • Page 30 INSTALLATION AND HARDWARE MANUAL PUMPS ADI 1075 Pilot System December 2002 CHAPTER 8 PUMPS The Pump Section contains four positions for pumps: Each pump position has a on/off/remote switch. In the position “on” the pump is on continuously. In the position “off” the pump is switched off.
  • Page 31 INSTALLATION AND HARDWARE MANUAL PUMPS ADI 1075 Pilot System December 2002 Ordering information: Z311500010 Fixed speed drive module 5 rpm, 230 Vac, Z311500011 Fixed speed drive module 6 rpm, 110 - 120 Vac, Z311500020 Fixed speed drive module 17 rpm, 230 Vac,...

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