Summary of Contents for UGO BASILE 47883
- Page 1 Instruction manual Librae Incapacitance tester July 2020 revision 2.2 Pain Inflammation SKU: 47883/ 47882/ 47885/ 47880-001...
- Page 2 Librae Incapacitance tester for mice and rats Product service and repair must be 47883/47882/47885/47880-001 performed by qualified personnel authorized by the Ugo Basile organization. is manufactured in compliance with the following European Union Directives and relevant harmonized standards • 2006/42/CE on machinery •...
- Page 3 Reliable data: high quality force sensor Librae package contents:: Incapacitance Tester for measuring hind paw (0.1g resolution) is easily calibrated using SKU: 47883 weight distribution using the most widely the reference weight supplied. The Librae Incapacitance tester for mice used method (>1,500 citations).
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Page 4: Table Of Contents
• The main unit, an original Ugo Basile design, see paragraph 2.1, incorporating the 2 force 3.5 Before Applying Power ............11 3.6 Intended Use . -
Page 5: Instrument Description
Back to contents 2.1.2 Animal Welfare The test results, can be browsed in a condensed view, as shown in Figure 2.1.3.3. In any analgesia test, great care must be taken to prevent the animal from experiencing any inadvertent harm. When an investigator initially begins using the incapacitance test, and when first assessing a new strain of animal, care must be taken to identify the appropriate amount of stimulus that will produce the desired response. -
Page 6: Installation
Back to contents 3 Installation 3.4 Assembling the instrument Place the instrument on a stable and flat surface where it will be used for tests. Adjust the four rubber feet until the instrument is level. Position the mouse or rat restrainer onto the base plate. 3.1 Unpacking &... -
Page 7: Intended Use
Do not operate in hazardous environments or outside prescribed environmental limita- tions, see paragraph 6.0 Do not spray any liquid on the connectors, display, or other parts Ugo Basile cannot in any way and form be held responsible for damage caused to things and people due to: •... -
Page 8: Operation
Back to contents 4 Operation On the home page, press the “UB logo” button to view software and memory information, as shown in Figure 4.1.3. Press the “UB logo”again to return to main menu page. Turn the instrument ON by using the ON/OFF power switch at the rear of the device. The instrument starts up and performs a system check, which might take up to 60 seconds. -
Page 9: Quick Setup For First Test
Back to contents 4.1.1 Quick setup for the first test 4.1.2 System Icons You are now ready to configure and run your first experiment. System icons are shown in Figure 4.1.1.1. The following steps will guide you to quickly configure Librae Incapacitance Tester and get your first results: Press the SETUP icon to configure your experiment (Refer to paragraph 4.3) Press the EXPERIMENT icon to fill in protocol, treatment, animal ID, etc... -
Page 10: Home
Back to contents 4.1.3 Home Page Icons TREATMENT: treatment or drug delivered to the animal. Depress the text field to enable a virtual keyboard (Figure 4.2.2). This is an alphanumeric field: enter a maximum of 12 characters. Figure 4.1.1 - Main Menu, with UB logo Home Page Main menu page (Figure 4.1.1) gives you access to the following commands: Figure 4.2.2 - Characters Virtual Keyboard Experiment: Enter information about the test, including treatment, protocol, stage, trials... -
Page 11: Setup
Back to contents 4.4 Start 4.3 Setup START screen (Figure 4.4.1) enables the starting and stopping of an experiment. Apply ZERO (tare) Use the Setup page (Figure 4.3.1) to configure the parameters of the experiment: to the measurement (if necessary), and see the applied force distribution. This feature is particularly useful to check the animal position inside the restrainer, and if the Animal Max Weight: this value allows you to rescale the histogram and the plot chart experiment is running correctly. -
Page 12: Calibration
NOTE: Before running the calibration wizard procedure, ensure that NO weight is applied on the Figure 4.6.1 shows the Autostart settings menu. food pads, AND a 100g calibrated weight is present. If necessary, Ugo Basile can supply a 100g calibrated weight. Refer to paragraph 7.0 for ordering details. - Page 13 Back to contents Figure 4.6.2 Figure 4.6.5- Autostart is waiting for stabilization time to elapse. AUTO icon is GREEN. START the experiment (Figure 4.6.3); Experiment runs until time-out (Figure 4.6.6) Figure 4.6.3 - Autostart is waiting for the minimum weight. AUTO icon is ORANGE. Figure 4.6.6 - Experiment is running Put the animal inside the restrainer (Figure 4.6.4);...
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Page 14: Utilities
Figure 4.7.1 4.7.1 Update This function allows you to update the software of the instrument. Before running the update procedure, check the installed firmware version (see Figure 4.1.3) and check Ugo Basile website Figure 4.7.2.1 for the latest version, (www.ugobasile.com) To perform a software update: 4.7.3 Advanced Settings... -
Page 15: Erase Db
Back to contents 4.7.4 Erase DB 4.7.6 USB Storage Erase DataBase button allows the deletion of ALL data and experiments stored on the Librae USB Storage menu (Figure 4.7.6.1) allows to save experimental data to USB memory key, Database. This funcion is normally NOT required. After the button is pressed, a Confirm window appears. -
Page 16: Communication Port Connection
Back to contents 4.8 Connections DB-15 Pin# Signal Name Signal Type Description Start/Stop TTL OUT Start -> TTL High Level 4.8.1 Communication port connection Stop -> TTL Low Level Manual/Autostart TTL OUT Manual -> TTL High Level Librae Incapacitance Tester is provided with a D-sub (DA-15 Female) TTL I/O port (see Figure Autostart ->... -
Page 17: Maintenance
Back to contents 5 Maintenance 6 Specifications General While any service or repairs of the instrument are performed by Ugo Basile, this section describes normal maintenance procedures that can be performed at your facility. Command Input 4.3’’ touch-screen (resistive) UNPLUG THE POWER CORD BEFORE CARRYING OUT ANY MAINTENANCE WORK Read-out 4.3’’... - Page 18 Back to contents Other Ugo Basile products related to this device Other Ugo Basile products related to this device visit ugobasile.com web site for details visit ugobasile.com web site for details Hot/Cold Plate for screening of thermal e-VF Handheld Electronic Von Frey of original TGR - Thermal Gradient Ring (Zimmermann’s...
- Page 19 Additional Ugo Basile products for motory coordination Visit ugobasile.com web site for details The 1st, original Mouse RotaRod for motory OPERON (Papaleo-Scheggia’s method) for coordination studies Attentional Set-Shifting Task Fear Conditioning System - ANYmaze Rodent Treadmill NG with interchangeable lane...