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Bioscience Ampulmatic-10 Operation And Maintenance Manual

Liquid filler accessory
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ISO 9001:2015 Certified
®
Ampulmatic
-10 Liquid Filler Accessory
Operation and Maintenance Manual
Bioscience, Inc.
2201 Hangar Place, Suite 200
Allentown, PA 18109
Phone: (484) 245-5232 Fax: (484) 245-5236
bioscience@bioscienceinc.com
www.bioscienceinc.com
Original Version (in English)
Revised April 19, 2018

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  • Page 1 ISO 9001:2015 Certified ® Ampulmatic -10 Liquid Filler Accessory Operation and Maintenance Manual Bioscience, Inc. 2201 Hangar Place, Suite 200 Allentown, PA 18109 Phone: (484) 245-5232 Fax: (484) 245-5236 bioscience@bioscienceinc.com www.bioscienceinc.com Original Version (in English) Revised April 19, 2018...

  • Page 2: Section Page

    Contents Section-Page Title Introduction Statement of Warranty Model Description Ampulmatic-10 Liquid Filler Features Unit Specifications Setup Initial Setup Installing the Liquid Filler Syringe Installing the Tubing Calibrating the Filling Volume Final Setup Adjusting the Syringe Speed Ampule Glass and Size...
  • Page 3 5232, 800-627-3069, or bioscience@bioscienceinc.com. All Rights Reserved The information contained in this manual is the exclusive property of Bioscience, Inc. and has been provided solely to enable the users of the equipment described herein to operate and maintain such equipment. Any other use of this information, or the reproduction or transmission of all or any portion of this manual, without prior written consent of Bioscience, Inc.

  • Page 4: Statement Of Warranty

    365 days from the date of shipment. This warranty is the only warranty made by Bioscience, Inc. (Manufacturer) and is in lieu of all other warranties, expressed or implied, except as to title and can be amended only by a written instrument signed by the Manufacturer.

  • Page 5: Model Description

    Purge Gas Injector accessory and the Ampulmatic-10 base unit. The Purge Gas Injector accessory is used to move a plunger head into each ampule prior to sealing, while the Liquid Filler accessory injects fluid through the plunger head into each ampule.
  • Page 6 Ampulmatic-10 Liquid Filler Features Safety Solenoid Switch Valve PTFE Tubing Solenoid PTFE Luer Lock Ferrules Syringe Syringe Black Knob Clamps Fasteners Lower Limit Switch Upper Limit Switch Switch Trigger Bracket...

  • Page 7: Unit Specifications

    Unit Specifications Overall Dimensions The overall dimensions of the Ampulmatic-10 Liquid Filler accessory are 8”W x 16”H x 8”D (20.3 cm W X 40.6 cm H X 20.3 cm D). Shipping Weight The shipping weight of the Ampulmatic-10 Liquid Filler accessory is approximately 27 lbs (12.25 Electrical Requirements All electrical parts are UL listed/approved.

  • Page 8: Initial Setup

    The switch on the front of the Liquid Filler accessory controls power to the Liquid Filler accessory only. Do not turn this switch on until the Ampulmatic-10 base unit, Purge Gas Injector accessory, and Liquid Filler accessory have been completely set up.
  • Page 9 NOTE: 1ml and 2.5ml syringes may be special ordered for small volume injection. Please contact Bioscience for more information. CAUTION: Use syringes provided by Bioscience, Inc. only. Other syringes may not be designed to fit in the unit. 2. Remove the front and rear white syringe clamps from the Liquid Filler base plate by unscrewing the black knob fasteners.
  • Page 10 Syringe Clamp Positioning 10ml Syringe 5ml Syringe 20ml Syringe 5. Extend the syringe plunger so that it reaches the switch trigger bracket. Insert the provided #6-32 screw through the bottom of the switch trigger bracket. Straight up and tighten with an allen wrench to grip the plunger of the syringe.

  • Page 11: Installing The Tubing

    Installing the Tubing For smaller fill volumes, 1/8” outer diameter (OD) tubing is used for 5 and 10 mL syringes (shown in the pictures below). This is preferred for more rapid startup (washing out previous solution or solvent, elimination of air bubbles, and easier sealing of connections). For larger fill volumes, ¼”...
  • Page 12 Calibrating the Filling Volume Caution: Potential pinch hazard. Do not put fingers inside the safety shield during operation. 1. Place an empty container under the Liquid Filler Injector Head to catch any fluid dispensed during the setup and calibration process. 2.

  • Page 13: Final Setup

    1. Connect the Liquid Filler accessory to the appropriate port on the Purge Gas Injector accessory using the cable provided. The Purge Gas Injector accessory should also be connected to the Ampulmatic-10 base unit. 2. If using both a Purge Gas Injector Head and a Liquid Filler Injector Head, verify that the Liquid Filler Injector Head is placed on the Purge Gas Injector Rod first.
  • Page 14 Adjusting the Syringe Speed The “Syringe Speed Adjust” controls the speed of the syringe as it dispenses liquid. The syringe must move fast enough to inject the liquid within the time it takes the Ampulmatic-10 base unit to flame seal an ampule.
  • Page 15 Standard carousels are designed for Wheaton gold band ampules or equivalent. Ampule samples or specifications should be provided to Bioscience to confirm compatibility. Custom carousels are available for non-standard ampule sizes.

  • Page 16: Maintenance

    Maintenance The Ampulmatic-10 Liquid Filler accessory was designed to require a minimum amount of maintenance. However, following the recommended maintenance procedures and intervals will ensure that you obtain the highest level of reliability and fluid injection accuracy. Daily (Before Use) •...

  • Page 17: Troubleshooting Guide

    Ampulmatic-10 base unit does not advance after connecting Liquid Filler accessory. Ampulmatic-10 base unit advances, but plunger heads do not go down into ampules. Ampulmatic-10 base unit advances, plunger heads go down into ampules, but Liquid Filler accessory does not pump syringe/inject liquid.
  • Page 18 If syringe does not move quickly enough to complete injection within cycle time of Ampulmatic- 10 base unit, you can: • Adjust dwell time on Ampulmatic-10 base unit to a longer period (turn the dwell dial counterclockwise). • Adjust “Syringe Speed Adjust” clockwise to move syringe faster.

  • Page 19: Spare Parts List

    Spare Parts List Part Syringe, 5ml 270 064 Syringe, 10ml 270 065 Syringe, 25ml 270 066 Safety shield switch 270 073 Syringe clamp, rear 270 054 Syringe clamp, front 270 055 Syringe clamp screws 270 056 Solenoid Valve 270 067 Swagelok SS ¼-28 to ¼”...

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