Bioscience Ampulmatic-10 Operation And Maintenance Manual
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Bioscience Ampulmatic-10 Operation And Maintenance Manual

Laboratory ampule sealer
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ISO 9001:2015 Certified
Ampulmatic
®
-10 Laboratory Ampule Sealer
Operation and Maintenance Manual
Bioscience, Inc.
2201 Hangar Place, Suite 200
Allentown, PA 18109
Phone: (484) 245-5232 Fax: (484) 245-5236
bioscience@bioscienceinc.com
www.bioscienceinc.com
Original Version (in English)
Revised March 22, 2018

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  • Page 1 ISO 9001:2015 Certified Ampulmatic ® -10 Laboratory Ampule Sealer Operation and Maintenance Manual Bioscience, Inc. 2201 Hangar Place, Suite 200 Allentown, PA 18109 Phone: (484) 245-5232 Fax: (484) 245-5236 bioscience@bioscienceinc.com www.bioscienceinc.com Original Version (in English) Revised March 22, 2018...
  • Page 2 Contents Section-Page Title Introduction Model Description Ampulmatic-10 Features – Front View Ampulmatic-10 Features – Back View Statement of Warranty Unit Specifications Where to Install Your Unit Unpacking and Assembly Setting Up Oxygen and Propane Gas Pressures/Flow Connecting to Compressed Gas Cylinders...
  • Page 3 Ampulmatic-10 ampule sealer can easily adapt to the sealing demands of a variety of ampule types, sizes and sources worldwide. We have had extensive experience dealing with the unique sealing problems of our customers over several decades and are proud to be the leader in bench-scale ampule sealing.

  • Page 4: Model Description

    (carousel). Corrosive liquids must be tested in advance of filling and sealing for compatibility with the materials of construction of the Ampulmatic-10 base unit and its accessories. Corrosion resistant replacement parts may be available. A variety of carousels are available to handle ampules of different sizes. They are designed to hold up to 20 ampules (with the exception of the 50 ml carousel which holds 10 ampules).
  • Page 5 Ampumatic-10 Features – Front View Torch Tip Bracket Torch Tip Ampule Spinning Drive Belt Optical Sensors Turntable Carousel Spindle Power Switch Dwell Time Adjustment...
  • Page 6 Ampumatic-10 Features – Back View Propane Tank Valve Attachment Torch Height Adjustment Oxygen Propane Needle Needle Valve Valve Oxygen Circuit Toggle Breaker Valve Power Inlet Propane Oxygen Tank Inlet Bracket...

  • Page 7: Statement Of Warranty

    365 days from the date of shipment. This warranty is the only warranty made by Bioscience, Inc. (Manufacturer) and is in lieu of all other warranties, expressed or implied, except as to title and can be amended only by a written instrument signed by the Manufacturer.

  • Page 8: Unit Specifications

    Unit Specifications Overall Dimensions The overall dimensions of the Ampulmatic-10 Ampule Sealer are 8.5” W x 12” H x 17” D (21.6 cm W x 30.5 cm H x 43.2 cm D). Shipping Weight The shipping weight of the Ampulmatic-10 Ampule Sealer base unit is approximately 21 lbs (9.53 Carousel Capacity Carousel racks are available from Bioscience, Inc.
  • Page 9 Note: Corrosive liquids must be tested in advance of filling and sealing for compatibility with the materials of construction of the Ampulmatic-10 base unit and its accessories. Special materials for corrosion resistant Ampulmatic-10 models may be available for specific applications by request.
  • Page 10 Where to Install Your Unit The Ampulmatic-10 ampule sealer should be installed on a level and stable bench or table with easy access to required electrical and gas supplies. It must be placed in an area with good ventilation due to its use of flammable gases and the production of by-products from combustion.

  • Page 11: Unpacking And Assembly

    1. Setting up Oxygen and Propane The Ampulmatic-10 ampule sealer requires the blending of a propane, MAPP, or natural gas source with oxygen in order to create a flame for sealing. These gases are generally available and are plumbed into the instrument with 1/8”...
  • Page 12 3. Connecting to Compressed Gas Cylinders The gas inlets to the Ampulmatic-10 base unit are 1/8” compression fittings. To connect to larger cylinders you will need to purchase a regulator and adapter for 1/8” OD tubing. McMaster-Carr is a vendor that supplies a wide range of equipment and components and will typically carry everything you need to get started.
  • Page 13 Clear Nylon Tubing 4. Placing the Carousel on the Turntable Place the carousel on the Ampulmatic-10 turntable by sliding the notched bottom of the carousel across the carousel turntable so that the center hole aligns with the hole in the turntable.
  • Page 14 Both washers should be on top of the torch tip assembly plate. Attach the rubber tubing from the torch tip to the hose barb fitting on the rear of the Ampulmatic-10. Next, place an ampule into the carousel one or two positions before the torch tip (carousel rotates clockwise).
  • Page 15 1. Lighting the Burner Each Ampulmatic-10 ampule sealer is tested by Bioscience, Inc. before leaving the factory. Factory gas flow settings should allow the flame to be ignited and (when oxygen is turned on) an ampule to be sealed with minimal adjustment of gas flows. If multiple sizes of ampules are to be sealed, however, adjustment may be necessary for each ampule size.
  • Page 16 <1 mL capacity to 50 mL capacity and made of various types of glass. As shipped from the factory, the Ampulmatic-10 sealer is set to a relatively short dwell time in order to seal more vials in a given time.
  • Page 17 Concentration of * Temperature (°C) Ice/water/NaCl* Excess -10 to -15 Ice/water/CaCl Excess Dry ice*/ethanol or isopropanol Excess -72 to -78 Dry ice*/ethylene glycol Excess Clean solvent spills up as soon as they occur to avoid damage to the Ampulmatic-10 components.
  • Page 18 Standard carousels are designed for Wheaton gold band ampules or equivalent. The Ampulmatic-10 Ampule Sealing System can be adapted to seal a variety of ampule designs and sizes. However, non-standard sizes or designs should be submitted to Bioscience to confirm suitability prior to purchase.
  • Page 19 Custom carousels may be available for other ampule sizes. Please contact your Bioscience, Inc. representative for more information. 7. Sealing Thick Glass Ampules A Dual Flame module is available for sealing thicker glass ampules. Contact your Bioscience Technical Representative for more information. 8. Opening the Sealed Ampules Sealed ampules are best opened by sliding an ampule breaker over the top of the ampule to the color break or scored line and then breaking with a bending motion.

  • Page 20: Maintenance

    Maintenance Make no attempt to service or repair the Ampulmatic-10 ampule sealer while still under warranty before consulting with Bioscience, Inc. After the warranty period, such consultation is still advised, especially when the repair may be technically sophisticated or difficult. No equipment, however, should be returned to the manufacturer without prior approval.
  • Page 21 The carousel advance motor speed is pre-set during manufacturing and does not need regular adjustment. Motor speed is controlled by an electronics board that can be programmed to operate at different speeds. Contact Bioscience if the speed needs to be reset.

  • Page 22: Troubleshooting Guide

    Troubleshooting Guide Problem Possible Causes Ampulmatic-10 Ampule • Power switch is OFF. Sealer does not turn on • Unit is not plugged in (or not plugged into a proper working outlet). • Power cord is not securely plugged into power transformer.
  • Page 23 Ampules are not properly • Flame temperature and/or dwell time should be adjusted (See “Flame sealed and Ampule Dwell Time Adjustment” under the “Operating Procedures” section of this manual). Ampules are breaking • Seals may be brittle if sealed at high temperature and quickly cooled (especially with “soft”...

  • Page 24: Replacement Parts List

    Replacement Parts List If you need replacement parts for your Ampulmatic-10 ampule sealer, please contact Bioscience, Inc. This is a list of the most commonly requested replacement parts and wear items. PART NUMBER (PCN) DESCRIPTION 210 001 Regulator valve for propane tank...

  • Page 25: Accessories List

    Accessories List PART NUMBER (PCN) DESCRIPTION 295 008 Purge Gas Injector module 295 009 Liquid Filler module Dual Flame module 290 002 Carousel rack (1 ml) – 20 ampule 290 003 Carousel rack (2 ml) – 20 ampule 290 004 Carousel rack (5 ml) –...

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