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Bruker BioSpec 70/30 USR V2 Manual

Bruker BioSpec 70/30 USR V2 Manual

Site planning information with magnet
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BioSpec 70/30 USR
●
Site Planning Information
with Magnet B-C 70/30 USR V2
Version V020
Preclinical Imaging
Innovation with Integrity

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Summary of Contents for Bruker BioSpec 70/30 USR V2

  • Page 1 BioSpec 70/30 USR ● Site Planning Information with Magnet B-C 70/30 USR V2 Version V020 Preclinical Imaging Innovation with Integrity...
  • Page 2 © February 21, 2018 Document Number: 9007201111482251 P/N: Site Planning Information BioSpec 70/30 USR For further technical assistance for this product, please do not hesitate to contact your nearest BRUKER dealer or contact us directly at: D-76275 Ettlingen Germany Phone: E-mail: Internet: www.bruker...

  • Page 3: Table Of Contents

    Contents Contents Introduction............................ 7 About this Manual ....................... 7 Overview .......................... 7 Additional Documents ...................... 7 Responsibilities ........................ 8 Validity .......................... 8 Safety.............................. 9 Safety during the Installation Phase ................... 9 Instructions to plan a safe and compliant MR Site............ 12 2.2.1 Magnetic Field........................ 12 2.2.1.1 Controlled Access Area .................... 13 2.2.1.2 Exposed Area ........................ 14 2.2.1.3...
  • Page 4 Contents 5.3.1.3 Effect of MR system to other equipment................ 30 5.3.1.4 Remote magnetic effects .................... 30 5.3.2 Electromagnetic interactions..................... 30 5.3.2.1 DC and LF interference..................... 31 5.3.2.2 RF interference ......................... 32 5.3.3 Mechanical interactions .................... 34 5.3.3.1 Ground and building vibrations .................. 34 5.3.3.2 Impact noise........................ 36 5.3.3.3 Acoustic .......................... 36 Planning Details.......................... 37 Measurements and room dimensions................ 37...
  • Page 5 Contents 6.10 Cold Water Supply ...................... 72 6.10.1 Connections and installation ..................... 74 6.11 Cryogenic Fluids ....................... 76 6.12 Helium Gas and Compressed Air Supply ................. 76 6.12.1 MRI CryoProbe™...................... 76 6.13 Laboratory Furnishings ..................... 78 6.13.1 Laboratory Furniture ...................... 78 Delivery and Transport ........................ 79 Maximum transport time .................... 80 Packaging ......................... 80 Magnet Transport...................... 81 7.3.1...
  • Page 6 Contents Site Planning Information BioSpec 70/30 USR_2_V020...

  • Page 7: Introduction

    System Owner, which must be met, before installation by Bruker Service may start. Chapter Laboratory infrastructure and interactions [}  27] describes the general and infrastructure specifications for the installation site within a laboratory.

  • Page 8: Responsibilities

    If there is a delay of receipt on the part of the System Owner after readiness for shipment has been sent to Bruker, the System Owner may be charged for the resulting additional costs. The regulations on a delay of receipt are established in the General Business Terms and the "Terms and Conditions"...

  • Page 9: Safety

    Installation, initial commissioning, retrofitting, repairs, adjustments or dismantling of the device must only be carried out by Bruker Service or personnel authorized by Bruker. Damage due to servicing that is not authorized by Bruker is not covered by your warranty. WARNING Warning of personal injury and/or damage to the MR Instrument and/or building.
  • Page 10 WARNING Risk of severe personal injury or explosion u Only Bruker Magnet Service may perform work on the magnet. u Do not open or remove any safety valves and/or burst disks of the magnet dewar. Site Planning Information BioSpec 70/30 USR_2_V020...
  • Page 11 Safety WARNING Risk of asphyxiation or severe burns by cryogen liquids The handling of cryogen liquids bears potential risk of severe personal injuries like burns or asphyxiation. Rapidly escaping helium or nitrogen as it occurs during the filling process of a magnet can possibly displace the air in the magnet room and can therefore be a potential risk for asphyxiation.

  • Page 12: Instructions To Plan A Safe And Compliant Mr Site

    Safety Instructions to plan a safe and compliant MR Site Laboratory infrastructure and operation of the MR instrument must be safe and compliant with regulatory. The following safety aspects need to be considered when planning the MR site. 2.2.1 Magnetic Field The super-conducting magnet of the MR instrument continually produces a very strong magnetic field inside of and outside of the magnet.
  • Page 13 Safety 2.2.1.1 Controlled Access Area The Controlled Access Area is the three-dimensional area in which the magnetic field strength is 0.5 mT and higher. It is defined by the 0.5 mT magnetic stray field line of the magnet. The contour maps of the magnetic stray field are provided in the System Owner Manual.

  • Page 14: Exhaust System

    Safety NOTICE Malfunction of laboratory equipment sensitive to magnetic fields Within the Controlled Access Area, the MR instrument can 1. interfere with electronic devices so that they might not work as intended 2. be influenced by electronic devices so that image quality can be affected u Always check accessories located in the Controlled Access Area for MR compatibility.

  • Page 15: Oxygen Supervision

    In order to establish a second safety level, most important for magnets that contain also N2, Bruker BioSpin MRI recommends the installation of an oxygen (O2) supervision and alarm system in the magnet room and in storage locations for cryogen fluid containers.

  • Page 16: Fire Prevention

    Repairs by Bruker BioSpin MRI can only be carried out after decontamination of equipment has been demonstrated in writing and any damage to the health of Bruker BioSpin MRI employees has been ruled out.

  • Page 17: User Work Safety Ds - Isoflurane - Rev0

    Safety • High noise levels originating from the magnet room and the technical room. • Ventilation in the magnet room, see Ventilation and air conditioning [} 69], Oxygen Supervision [} 15]. • Extraction of anesthetic gases where applicable, see Anesthetic gas extraction [} 71].
  • Page 18 USER WORK SAFETY Data Sheet Isoflurane Anesthesia Gas 1-Chloro-2,2,2-Trifluoroethyl Difluoromethyl Ether; 2-Chloro-2-(Difluoromethoxy)-1,1,1-trifluoro Ethane; Forane The substance/gas, ISOFLURANE, carries the CAS-no. 26675-46-7, regulated by the European REACH regulation 1907/2006. Isoflurane, a halogenated anesthetic gas, is a potential health hazard and safety procedures should be followed before/during its use to reduce risks (see MSDS of supplier)! General Information: 247-897-7 CAS#...

  • Page 19: Infrastructure Supervision And Messaging

    • automatic messaging for example via email or phone message to the supervising headquarter and/or staff in charge. Bruker BioSpin MRI is not responsible for the connection to the supervision network or messaging system and not liable for failures or any possible damage caused when connecting the MR instrument to this system.
  • Page 20 Safety Site Planning Information BioSpec 70/30 USR_2_V020...

  • Page 21: Standards

    Electrical Equipment for Measurement, Control, and Laboratory Use • IEC 61326-1 Electromagnetic Compatibility (EMC) Upgraded instruments may not be EMC compliant. Bruker does not guarantee compliance with electromagnetic compatibility for upraded MR instruments that maintain old reused parts. Environmental Conditions The following environmental conditions must be fulfilled to maintain electrical safety at the installation site.

  • Page 22: National Standards Operating Mr Instruments

    Standards National Standards Operating MR Instruments Compliance with all national standards for operating MR instruments is in the responsibility of the System Owner (responsible body). The references to national standards listed in this document should not be regarded as complete or as generally valid. Site Planning Information BioSpec 70/30 USR_2_V020...

  • Page 23: Installation Schedule

    Installation Schedule Installation Schedule Installation planning overview Planning for a BioSpec® installation comprises the following subject areas: • Characterization the planned installation site in terms of its suitability for MR • Planning the laboratory structure and operational procedures • Planning the structure of rooms and buildings •...
  • Page 24 Installation Schedule Top left Magnet front view fitted with the AutoPac™ positioning system Top right Rear view of the magnet with CCM and an installed MRI CryoProbe™ Bottom left Control electronics of an MR system with three cabinets (no cooling cabinet) Bottom right Cooling unit, compressor and gas cylinder of the MRI CryoProbe™...

  • Page 25: Planning Aids

    The chronological sequence of a complete system installation is shown in the following illustration. The deadline for transferring the magnet planned at the outset and agreed with Bruker BioSpin MRI must be confirmed as binding to Bruker BioSpin MRI 12 weeks at the latest prior to actual transfer. See chapter Giving notice of readiness for shipment [} 25]...

  • Page 26: Prerequisites For Operation

    • During the installation period, it must be guaranteed that only people authorized by the Bruker employee have access to the installation site. • The Bruker employee needs to obtain a key allowing access the installation site. If necessary, he must be allowed access to adjacent rooms and/or buildings and circuit diagrams, as well as facilities and systems in the building.

  • Page 27: Laboratory Infrastructure And Interactions

    • Data archiving on central servers. • Data exchange between the operator console and analysis consoles. If it is possible to connect externally to the Internet, support of operators by Bruker Service & Lifecycle Support is improved: • Data exchange between operator and hotline •...

  • Page 28: Magnetic Interactions

    Laboratory Infrastructure and Interactions Interactions The MR instrument and its surrounding may affect each other based on the following interactions: • magnetic interactions • electromagnetic interactions • building vibrations and impact noise • room air and cooling systems We distinguish •...

  • Page 29: Mobile Sources Of Magnetic Disturbance

    Table Table 5.1 [} 29]. If this cannot be avoided, counter-measures should be taken by the builder, e.g. by shielding with soft-magnetic iron. Consult your local Bruker BioSpin MRI branch on the use of counter-measures. Minimum distance [m] Mobile sources of magnetic disturbance ferromagnetic objects <...

  • Page 30: Effect Of Mr System To Other Equipment

    Laboratory Infrastructure and Interactions Minimum distance [m] Mobile sources of magnetic disturbance ferromagnetic objects < 250 kg ferromagnetic objects < 500 kg ferromagnetic objects < 5000 kg ferromagnetic objects > 5000 kg subways, trucks, trains Table 5.1: Limit values of magnetic disturbances 5.3.1.3 Effect of MR system to other equipment The stray field of the MR system can lead to sustained disturbance of sensitive equipment in the vicinity of the system and to irreversible damage.

  • Page 31: Dc And Lf Interference

    Laboratory Infrastructure and Interactions Electromagnetic disturbances to the MR system have a negative impact on the disturbance- free operation of an MR system. Electromagnetic disturbances are either associated with conducted disturbances or transmitted by electromagnetic fields. It can be split into the following categories: •...

  • Page 32: Rf Interference

    If this cannot be avoided, countermeasures with in the building can also be taken, e.g. by using an active shield (MACS) in the HF shielding cabin or by shielding with soft-magnetic iron. Contact the planning office of your local Bruker BioSpin MRI branch. 5.3.2.2...

  • Page 33: Figure 5.2: Installation In An Rf Shielded Cabin (Faraday Cage)

    Laboratory Infrastructure and Interactions 19F–1H X nuclei (15N-31P) 30 dBµV/m 30 dBµV/m Table 5.7: Maximum disturbance level If increased disturbance is observed in this area, the frequency range concerned must be analyzed more precisely and one of the following counter-measures taken when planning installation: Countermeasure The safest countermeasure is the installation of an MR system in an HF shield.

  • Page 34: Mechanical Interactions

    Laboratory Infrastructure and Interactions Figure 5.3: Installation with an AutoPac™ RF shield RF shielding at the user end of the magnet Acoustic insulation RF shielded magnet housing RF shielding at the service end of the magnet RF shielded electronics cabinets The magnet itself is RF shielded. Other shielded areas are marked in blue 5.3.3 Mechanical interactions 5.3.3.1...

  • Page 35: Figure 5.4: Limit Values Of The Floor Vibrations

    If none of the alternatives mentioned can be realized, additional passive or active vibration decoupling must be evaluated by the builder. Please contact an engineering firm specializing in building vibrations for this and contact your local Bruker BioSpin MRI branch. Site Planning Information BioSpec 70/30 USR_2_V020...

  • Page 36: Impact Noise

    Laboratory Infrastructure and Interactions 5.3.3.2 Impact noise No significant coupling of impact noise into the building is to be expected due to the installation of the MR magnets on passive absorbers. 5.3.3.3 Acoustic Increased sound levels occur in the following areas of an MR system: •...

  • Page 37: Planning Details

    Planning Details Planning Details Details of preparation of various parts of the installation are provided in the following chapters. Due to the fact that multiple specialists are involved in the planning, the contents are divided accordingly. Measurements and room dimensions 6.1.1 Overview The room dimensions and the distances between the different areas of an MR system are...

  • Page 38: Operating Area

    Planning Details 6.1.2 Operating area The minimum amount of space required in the operating area is indicated by the size of the laboratory furniture. This must allow installation of a PC control computer with monitor and peripherals. Additional specifications for the space required may result from local guidelines for organizing the work place, from the number of MR datastations planned and from the operational procedures and routes planned.

  • Page 39: Table 6.1: Minimum Space Required For Magnets 70/30 Usr V2

    Planning Details Space required 70/30 USR V2 Dimensions Value Access door, minimum width for He refill can 100 cm Table 6.1: Minimum space required for magnets 70/30 USR V2 Site Planning Information BioSpec 70/30 USR_2_V020...

  • Page 40: Figure 6.3: Stray Field Of Biospec® Based On Magnet 70/30 Usr V2

    Planning Details Figure 6.3: Stray field of BioSpec® based on magnet 70/30 USR V2. Site Planning Information BioSpec 70/30 USR_2_V020...

  • Page 41: Technical Area

    Planning Details RF shielded cabin (Faraday Cage) Use of a Faraday Cage increases the size of the building shell needed for the magnet area in each direction by at least 30-40 cm. The height of the ceiling may be increased depending on the design by up to 65 cm.

  • Page 42: Rf Shielded Room

    Planning Details Unit Number Size (width x length x height) Electronic Cabinets each 60 x 80 x 200 cm 90 cm 55 cm High Power Gradient 60 x 90 x 200 cm 90 cm 45 cm Cabinet Cooling Unit (DLHE) 80 x 80 x 200 cm 90 cm 55 cm Line Power Distributor...

  • Page 43: Filter Plates

    Filter plate Supplier (supplier) electronic filter plate feed of power lines • contained in the basic equipment of the control • supplied by Bruker electronics magnet filter plate feed for USR • contained with USR magnets magnets • supplied by Bruker...

  • Page 44: Table 6.4: Use Of Filter Plates

    CryoProbe™: CryoProbe™ option • supplied by Bruker in-vivo filter plate feed for lines for • optional order from Bruker animal monitoring cabin ventilation RF filters for • contained in the RF cabin option ventilation and fresh • supplied by Bruker...

  • Page 45: Figure 6.5: Assembly Of Filter Plates With An Installation Frame (Right) And Directly Screwed To The Cage (Left)

    Planning Details Figure 6.5: Assembly of filter plates with an installation frame (right) and directly screwed to the cage (left) sheet copper of the Faraday cage external insulation of the shielding box Allen screw with spring ring and washer RF sealing tape filter plate inner lining and inner frame of the filter plate opening aluminum frame on which to place the filter plate...

  • Page 46: Figure 6.6: Dimension Diagram Of Filter Plates

    Planning Details Figure 6.6: Dimension diagram of filter plates Height Width Diameter of the bores Horizontal distance to first hole Vertical distance to first hole Horizontal distance between holes Vertical distance between holes Horizontal distance from edge of filter plate to center of bore hole Vertical distance from edge of filter plate to center of bore hole Maximum frame width If there are no detailed drawings for the filter plates described below, the measurements to...

  • Page 47: Electronic Filter Plate

    Planning Details Filter plate [mm] Electronics 410 1100 Magnet Anesthetic gas 87,5 87,5 extraction Magnet exhaust vent MRI CryoProbe 12,5 12,5 122,5 12,5 12,5 In-vivo Ventilation See chapter Filter plate for Faraday cage ventilation [} 48] Table 6.5: Measurements of the individual filter plates Example calculation for the wall opening of the magnet filter plate: Wall opening magnet filter plate (width): B –...

  • Page 48: Filter Plate For Magnet Exhaust System

    Planning Details For further details, please see chapter Anesthetic gas extraction [} 71]. 6.2.1.4 Filter plate for magnet exhaust system Position, alignment, and assembly • On the ceiling or on the side wall beneath the ceiling of the Faraday cage. • The ideal position is determined by the position of the external outlet of the exhaust vent. The position should be selected so that the length between magnets and outlet is minimal and can be produced with as few bends as possible (see chapter Exhaust system...

  • Page 49: Exhaust System

    • Vent outlet design • Electrical grounding Your local Bruker BioSpin office will be happy to help you with planning the exhaust vent and is able to supply you on request with suitable quench pipe components. Site Planning Information BioSpec 70/30 USR_2_V020...

  • Page 50: Design Criteria Of The Exhaust System

    Planning Details Figure 6.7: Example of an exhaust vent system. 6.3.1 Design criteria of the exhaust system The exhaust system must be designed and calculated in such a way that: • The connection of the exhaust vent is immediately above the magnet's outlet point. •...

  • Page 51: Figure 6.8: Drawing Of The Magnet Exhaust Outlet (1) And The Exhaust System (2). Note That (1) Is Supplied By Bruker And (2) Is To Be Installed By The System Owner

    Figure 6.8: Drawing of the magnet exhaust outlet (1) and the exhaust system (2). Note that (1) is supplied by Bruker and (2) is to be installed by the System Owner. Position of the connection point between the magnet exhaust outlet and the...

  • Page 52: Calculating The Exhaust System

    Planning Details 6.3.2 Calculating the exhaust system The following aspects must be considered when calculating the exhaust system: • effects of force in the event of quenching • Pressure drop along the duct The following table provides the effects of force on 90° bends for different pipe diameters. The exhaust vent must be installed so that it is able to withstand the forces listed in the event of quenching.

  • Page 53: Figure 6.9: Schematic Of The Exhaust Vent

    Planning Details Figure 6.9: Schematic of the exhaust vent. Segment L [m] D [mm] Pos [m] DP [mbar] 0.5 x 1.4 = 0.7 90° bends 20.0 1.8 x 1.4 = 2.52 90° bends 20.0 3.5 x 1.4 = 4.9 90° bends 2 x 2.8 = 5.6 90°bends 4 x 2.8 = 11.2...

  • Page 54: Floor Construction

    Please note that the given operation weights do not include the seismic safety option which must also be considered in addition. For further information please contact your local Bruker BioSpin MRI office. Note that in addition to the footprint given in the table, additional space to access and operate the components is required (see the corresponding chapters within this document).

  • Page 55: Magnet Foundation

    Specific solutions are possible in special cases for achieving load distribution in existing buildings. These solutions should be analyzed in relation to their vibration behavior. Discuss the situation and possible counter-measures with the planners from your local Bruker BioSpin MRI office.

  • Page 56: Figure 6.11: Schematic Drawing Of The Footprint Of The Magnet: (1) Position And Size Of The Vibra

    Planning Details Figure 6.11: Schematic drawing of the footprint of the magnet: (1) Position and size of the vibration absorbers supporting the magnet. (2) Position of the magnet exhaust vent. (3) Magnet foundation: the size of the foundation as well as the exact position of the magnet on the foundation need to be determined by the local building construction engineer.

  • Page 57: Electrostatic Discharge

    When installation is completed correctly, seismic safety is verified by statistical calculations in these cases up to the limit values listed below. Copies of the verified calculations can be requested from the local Bruker BioSpin MRI office. WARNING Warning of serious injury due to uncontrolled moving objects during an earthquake.

  • Page 58: Figure 6.12: Seismic Protection System In A Rf Shielding Box With "Faraday Cage Connection Kit

    Planning Details Properties Specification Floor anchor type exclusive use of the high-performance anchor supplied by type: Fischer HFB IL Floor anchor assembly installation according to the assembly instructions of the anchor type listed Table 6.10: Floor construction and anchorage for seismic safety Figure 6.12: Seismic protection system in a RF shielding box with "Faraday Cage Connection Kit.

  • Page 59: Electrical Installations

    Planning Details Figure 6.13: Seismic protection system at the magnet. Electrical installations 6.5.1 Overview Electrical installation comprises the following planning and work package: • Preparation of the electrical house connection • Preparation of a local equipotential bonding in the technical area •...

  • Page 60: Figure 6.14: Tn-S Connection Diagram Of The Mr Instrument (60Hz)

    Planning Details Figure 6.14: TN-S connection diagram of the MR instrument (60Hz) Earthing point of the building to be connected to the Bruker Line Power Distributor (2) directly, or via an additional equipotential bonding bar (1b). Additional equipotential bonding bar to connect additional equipment other than MR instrument components.

  • Page 61: Figure 6.15: Tn-S Connection Diagram Of The Mr Instrument (50 Hz)

    Planning Details Figure 6.15: TN-S connection diagram of the MR instrument (50 Hz) Earthing point of the building to be connected to the Bruker Line Power Distributor (2) directly, or via an additional equipotential bonding bar (1b). Additional equipotential bonding bar to connect additional equipment other than MR instrument components.

  • Page 62: Equipotential Bonding

    The MR instrument requires an equipotential bonding supply from the main ground that is to be connected to the equipotential bonding within the Bruker Line Power Distributor (LPD). From the LPD, all components of the MR instrument are supported. No other equipment may be connected to the Bruker LPD.

  • Page 63: Line Power Distributor

    Planning Details 6.5.6 Line Power Distributor The installation of the Line Power Distributor and the connection to the main power supply is the System Owner's task. In order to be able to finish the electrical installation before installation of the MR instrument begins, the Line Power Distributor can be delivered in advance.

  • Page 64: Supervision Signals

    Detailed planning of cable lengths and compliance to these plans during the final installation is a basic prerequisite for smooth installation of an MR system. The local project leader must immediately notify Bruker BioSpin MRI of any change to the cable lengths required during the planning stage. Changes to construction of the installation, which only become known during installation of the system, lead to enormous time delays.

  • Page 65: Figure 6.17: Overview Of The External Line Set

    Planning Details Figure 6.17: Overview of the external line set 1 (*) Control cables to the operating room. Cables are routed through a cable duct (min 10 cm diameter) or on a small cable tray that the customer must provide. Scanner control line: Cable set in the shielded cabin. Cables are routed on a cable tray assembled at ceiling height.

  • Page 66: Figure 6.18: Cable Routing Between Technical Room And Magnet Room

    Planning Details The external cable set is run along the open cable trays assembled at ceiling height. The customer must have the cable trays installed and completely finished before installation of an MR system begins on site. Access for placing cables in the cable tray must be freely available during installation of an MR system.

  • Page 67: Figure 6.19: Construction Of Cable Carrying System

    Planning Details Figure 6.19: Construction of cable carrying system Site Planning Information BioSpec 70/30 USR_2_V020...

  • Page 68: Line Lengths For The Mri Cryoprobe

    Planning Details 6.7.1 Line lengths for the MRI CryoProbe The following additional components must be considered when planning the cable routes when an MRI CryoProbe™ is planned to be used. See Table Table 6.3 [} 42] Power supply for CRP components Helium gas cylinder CRP compressor CRP cooling unit...

  • Page 69: Lighting System

    Planning Details Lighting system The lighting facility is not an integral part of the supply and must be finished by the customer before installation begins. There are no system specific requirements for the operating and technical rooms. When selecting the lighting facility in these areas, the country specific specifications and requirements for work place lighting must be met (occupational standards).

  • Page 70: Air Conditioning Systems

    Planning Details 6.9.2 Air conditioning systems It must be noted when planning the outlet openings of the space cooling that the air flow produces indirect cooling. The cold air flow must not be directly aimed at parts of the MR system.

  • Page 71: Anesthetic Gas Extraction

    Planning Details Equipment options: Additional requirements for the Additional cooling space cooling for the technical room performance Option: High Power Gradient Amplifier 7 kW Option: MRI CryoProbe™ 1.2 kW Option: Parallel Transmit Cabinet 2.0 kW Table 6.18: Additional requirements for the space cooling in the technical room 6.9.3 Anesthetic gas extraction If anesthetic gases are to be used, attention must be paid to the local regulations on...

  • Page 72: Cold Water Supply

    Set for anesthetic gas extraction. The set shown in the figure above may be purchased from Bruker upon request (part number T11976). If the instrument is installed within an HF shielded room, suitable connectors, extensions, and HF filtered feed through elements can be purchased from Bruker, part number T11976. 6.10 Cold Water Supply Part of the heat dissipated from the MR instrument is released via a heat exchanger to a cold water supply system (Primary Water Circuit).

  • Page 73: Figure 6.21: Relation Between The Primary Water Circuit Inlet Temperature And The Required Pri- Mary Flow For The Maximum Cooling Requirement Of 12 Kw (Standard Configuration Without Cryoprobe Option)

    Planning Details Figure 6.21: Relation between the Primary Water Circuit inlet temperature and the required Primary Flow for the maximum cooling requirement of 12 kW (standard configuration without CryoProbe option). Water quality Specification pH range 6.5 – 8.2 hardness 5.6 – 11.2 °d maximum proportion of glycol in the water 30 % chloride...

  • Page 74: Connections And Installation

    2.2 m. The cold water system lines of the building side must have a cross- section of at least 1" and be thermally insulated. Bruker BioSpin MRI recommends on-site installation of a temperature and pressure probe/ regulation for monitoring the properties of the cold water system going to the MR system.
  • Page 75 (inside or outdoors) can be included in the plans. These systems are to be planned, installed, and maintained by local refrigeration technology firms. Bruker BioSpin can help with planning and supplying these systems if necessary, but not with installing and maintaining them.

  • Page 76: Cryogenic Fluids

    • He regulator (regulates pressure to 22-25 bar, 320-360 psi) and charging hose are country specific and need to be ordered from Bruker and configured when ordering the CryoProbe™. Please provide information on He gas bottle. Common outlet types are:...
  • Page 77 Planning Details • Consider the He hose connection between Cryo Platform and He gas supply in the Technical room during installation planning. • Information: Estimated He gas consumption is about a 50 liter bottle/year, depending on the use of the CryoProbe™. The He connection must not be detached while in cold operation.

  • Page 78: Laboratory Furnishings

    Laboratory Furnishings 6.13.1 Laboratory Furniture The laboratory furniture is not supplied by Bruker. At the time the MR instrument is delivered, a sufficiently large desk for the workstation and an office chair must be provided by the System Owner. CAUTION Injury by attracting magnetic objects Only non-magnetic furnishings should be used within the Controlled Access Area.

  • Page 79: Delivery And Transport

    Magnet and electronics installation must always be planned and carried out in close cooperation with the local Bruker office. On the day the magnet is placed, a Bruker employee must be on site. Planning of delivery and transport must comprise the following items: •...

  • Page 80: Maximum Transport Time

    The magnet is transported and delivered cold. This therefore results in a maximum transport time of 10 days between the time that the magnet is picked up at Bruker and installation at the customer's. If it can be predicted at the planning stage that this maximum time span cannot be adhered to, appropriate intermediate storage must be planned which includes liquid helium filling of the magnet.

  • Page 81: Magnet Transport

    Only companies qualified to carry out specialized forms of transportation may be used and the Handling Instructions specified by Bruker are to be followed. 7.3.1...

  • Page 82: Figure 7.3: Transportation Using Heavy Duty Rollers

    Delivery and Transport – The load-bearing capacity must be checked and guaranteed along the entire transport route. – The transport route must be smooth, free of joints and steps, and not have only a small slope at most. The following transport limitations should not be exceeded during any transport procedures: transport restrictions 70/30 USR V2 Limit Maximum horizontal acceleration...

  • Page 83: Transporting Electronic Cabinets

    Delivery and Transport Transporting Electronic Cabinets The electronics cabinets contain sensitive and sometimes very heavy assemblies. Sometimes the cabinets have a high center of gravity and are therefore in danger of tipping. The cabinets may not be tipped during transportation, they may not get wet and they may not be subject to high acceleration and jolting.
  • Page 84 Delivery and Transport Figure 7.4: Transport dimension of the magnet 70/30 USR V2 . If shown in the figure and where applicable, alternative transport holdings exist: (1) standard transport situation and (2) for the case, when the U-rails are removed. (3) and (A) are additional transport options that are only available for 11 cm magnets. Additional weight to be considered during transport.
  • Page 85 Delivery and Transport If necessary, the magnet's U-rails can be removed for transport in the building. Figure 7.5: Unloading situation of transport by lorry The magnet and electronics must be unloaded from the particular means of transport at the installation site with a crane and this requires adequate free surfaces in the entrance area. The transport route must have the following features along its entire stretch: •...

  • Page 86: Moving Under Special Circumstances

    If there are no suitable transport routes within the building to the magnet's installation site, special procedures for moving it may be used. In these instances, please contact the local Bruker BioSpin MRI office to plan the best solution together with them.

  • Page 87: Moving Or Dismantling The Mr Instrument

    Suitable pressure valves must be mounted. Disposal of an MR instrument must be compliant with local regulations. Contact the planning office of your local Bruker BioSpin MRI branch. Residual magnetization in the building Increased residual magnetization in the building's ferromagnetic materials can remain after an MR system has been dismantled.
  • Page 88 Moving or Dismantling the MR Instrument Site Planning Information BioSpec 70/30 USR_2_V020...

  • Page 89: Checklist In Preparation Of The Installation

    6 weeks prior to the scheduled installation date and sent, signed, to your Bruker BioSpin MRI branch. If the completed check list does not reach the local Bruker BioSpin MRI branch in time, installation on the scheduled date may be canceled or postponed.

  • Page 90: Magnet Installation

    Is the transportation company adequately insured against transport damage so that the value of the MR system is covered? (Transport from the loading ramp at Bruker BioSpin MRI to the installation site.) Did the transport company visit the installation site and did...

  • Page 91: Laboratory Rooms Features

    Is a separate and lockable room close to the MR system available that can be used solely by Bruker BioSpin MRI during the installation? Are the installation rooms (MR area) lockable and the key...
  • Page 92 Checklist in Preparation of the Installation Magnet room, area where the magnet is located: Is the quench line correctly calculated and installed, accordingly? Due to the safety aspect of the quench line, the System Owner (responsible body) has to verify the correct installation of the quench line.

  • Page 93: Declaration

    Checklist in Preparation of the Installation Declaration As the person named responsible for the MR instrument by the customer, I hereby confirm the details given beforehand: Place, date: _____________________________________________________ Name: __________________________________________________________ (in block letters) Signature: ____________________________________________________ Site Planning Information BioSpec 70/30 USR_2_V020...
  • Page 94 Checklist in Preparation of the Installation Site Planning Information BioSpec 70/30 USR_2_V020...
  • Page 95 Example of an exhaust vent system................Figure 6.8: Drawing of the magnet exhaust outlet (1) and the exhaust system (2). Note that (1) is supplied by Bruker and (2) is to be installed by the System Owner......Figure 6.9: Schematic of the exhaust vent..................
  • Page 96 Figures Figure 7.4: Transport dimension of the magnet 70/30 USR V2 . If shown in the figure and where applicable, alternative transport holdings exist: (1) standard transport situation and (2) for the case, when the U-rails are removed. (3) and (A) are additional transport options that are only available for 11 cm magnets.
  • Page 97 Tables Tables Table 5.1: Limit values of magnetic disturbances ................Table 5.2: Interference fields of equipment ..................Table 5.3: Disturbance in the magnet room..................Table 5.4: Disturbance in the technical room ..................Table 5.5: Disturbance in the vicinity ....................Table 5.6: Frequency ranges for commonly used NMR nuclei ............
  • Page 98 Tables Site Planning Information BioSpec 70/30 USR_2_V020...

  • Page 99: Index

    Index cryogen gas lines .......... 64 Index Cryogen liquids.......... 76 Cryogenic fluids handling............ 14 storage ............ 14 Transport ............. 14 cryogenic gases .......... 49 Acoustic ............ 36 sound level .......... 36 acoustic absorption .......... 36 Air conditioning systems........ 70 DC consumers.......... 31 outlet openings .......... 70 DC interference .......... 31 air pressure subways ............ 31 Consumption .......... 76 decontamination .......... 16 Minimum pressure........ 76...
  • Page 100 Index Fire department ........... 15 Floor construction .......... 58 fire extinguishers ......... 15 fluxgate magnetometer........ 31 non-magnetic emergency equipment .. 15 forklifts or cranes .......... 29 Police............ 15 Fresh and ventilation ........ 48 entrance area ........... 85 air conditioning .......... 48 Equipotential bonding ........ 62 functional specifications of the MR instrument . 28 exhaust ............. 48 exhaust Pressure drop ........ 52 exhaust vent ............. 14...
  • Page 101 Index HF shielded cabin.......... 65 Cooling performance of the air-conditioning HF shielded room system in the magnet room .... 70 disturbing HF electromagnetic radiation.. 42 magnet room lighting ........ 69 HF-interference .......... 33 Magnet Service .......... 76 High frequency interference ...... 31 Magnet transport .......... 81 Humidity ............ 70 acceleration .......... 81 jolts .............. 81 transport devices ......... 81...
  • Page 102 Index Magnet box.......... 80 Measurements of the MRI CryoProbe™ .. 42 passive vibration absorbers...... 34 Minimum space required ...... 41 Pipelines ............ 28 MRI CryoProbe™ ........ 41 preparation ............ 27 MRI Parallel Transmit™ ...... 41 pressure control.......... 76 Technical modifications ........ 8 Pressure drop in USR magnet cable elements  52 Technical room ........ 16, 17, 31 cable lengths .......... 66 condensation in the technical room..... 75...
  • Page 103 Site Planning Information BioSpec 70/30 USR_2_V020...
  • Page 104 ● Bruker Corporation info@bruker.com www.bruker.com Order No: Site Planning Information BioSpec 70/30 USR...

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