Lenovo ThinkCentre 6416 Maintenance Manual page 106

6. Install the new Media Card Reader into the chassis and align the screw-hole in
the Media Card Reader with the hole in the chassis.
7. Install the screw to secure the Media Card Reader to the chassis.
8. Connect the Media Card Reader cable to the system board.
9. Go to "Completing the FRU replacement" on page 103.
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Hardware Maintenance Manual