Microtek ScanWizard Bio Reference Manual page 20

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By the default, the Auto Focus function is not activated when your Scan Material
is set as Reflective or Transmissive. If you like to apply the Auto Focus function
to your scanned materials, you need to go to the Preference menu and to select
the More command, and then check the Auto Focus to activate this option.
14 Microtek ScanWizard Bio Reference Manual
Select and apply the Auto Focus function to a specific area of the scan
frame by yourself.
Scan Frame Scan Frame
a) Select the Scan Frame Scan Frame Scan Frame tool from the Toolbar in the Preview window,
and choose the area to be scanned by dragging a rectangle around it.
Auto Focus Auto Focus
b) Select the Auto Focus Auto Focus tool from the Toolbar in the Preview window, Auto Focus
and select the area in the scan frame to which the AF function will be
applied.
A redefined Auto Focus frame (bordered in red) will appear within the
scan frame, labeled with the tag "AF".
The Auto Focus function
is not activated.
The Auto Focus
function is activated.