Lexus RX 450h 2010 Owner's Manual page 643

6-1. Specifications
NOTICE
Notice on fuel quality
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Do not use improper fuels. If improper fuels are used the engine will be damaged.
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Do not use leaded gasoline.
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Leaded gasoline can cause damage to your vehicle' s three-way catalytic convert-
ers causing the emission control system to malfunction.
Do not use gasohol other than that stated here.
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Other gasohol may cause fuel system damage or vehicle performance problems.
Using unleaded gasoline with an octane number or rating lower than that stated
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here will cause persistent heavy knocking.
At worst, this will lead to engine damage.
Fuel-related poor driveability
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If after using a different type of fuel, poor driveability is encountered (poor hot start-
ing, vaporization, engine knocking, etc.), discontinue the use of that type of fuel.
When refueling with gasohol
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Take care not to spill gasohol. It can damage your vehicle's paint.
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