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WATERS CORPORATION TQ Manuals
Manuals and User Guides for WATERS CORPORATION TQ. We have
1
WATERS CORPORATION TQ manual available for free PDF download: Operator's Manual
WATERS CORPORATION TQ Operator's Manual (192 pages)
Brand:
WATERS CORPORATION
| Category:
Security Sensors
| Size: 1 MB
Table of Contents
Copyright Notice
2
Contacting Waters
3
Safety Considerations
4
Canada Spectrum Management Emissions Notice
6
Electrical Power Safety Notice
6
Safety Hazard Symbol Notice
6
Equipment Misuse Notice
7
Safety Advisories
7
Operating this Instrument
8
Applicable Symbols
8
Intended Use
9
Calibrating
9
Quality Control
10
ISM Classification
11
EC Authorized Representative
12
Table of Contents
13
1 Waters TQ Detector
19
Overview
20
Waters TQ Detector
20
ACQUITY TQD UPLC/MS System
22
Software and Data System
22
Ionization Techniques and Source Probes
24
Electrospray Ionization (ESI)
24
Ion Optics
25
MS Operating Modes
26
MS/MS Operating Modes
27
Product (Daughter) Ion Mode
27
Precursor (Parent) Ion Mode
28
Multiple Reaction Monitoring Mode
28
Constant Neutral Loss Mode
29
Sample Inlet
30
Leak Sensors
30
Vacuum System
30
Rear Panel
31
Intellistart Fluidics System
32
Overview
32
System Operation
33
2 Preparing for Operation
35
Starting the Instrument
36
Configuring Intellistart
38
Verifying the Instrument's State of Readiness
38
Tuning and Calibration Information
38
Running the Instrument at High Flow Rates
38
Monitoring the Instrument Leds
39
Preparing the Intellistart Fluidics System
40
Installing the Solvent Manifold Drip Tray
40
Installing the Reservoir Bottles
41
Diverter Valve Positions
42
Purging the Infusion Syringe
45
Rebooting the Instrument
45
Rebooting the Instrument by Pressing the Reset Button
45
Leaving the Mass Spectrometer Ready for Operation
46
Emergency Instrument Shutdown
46
3 ESI Operation
47
Introduction
48
Installing the ESI Probe
48
Removing the ESI Probe
52
4 Maintenance Procedures
53
Contents
54
Topic Page
54
Maintenance Schedule
55
Spare Parts
56
Troubleshooting with Connections INSIGHT
56
Safety and Handling
57
Preparing the Instrument for Work Performed on the Source
59
Operating the Source Isolation Valve
60
Removing O-Rings and Seals
62
Cleaning the Instrument's Exterior
63
Emptying the Exhaust Trap Bottle
63
Emptying the Roughing Pump Exhaust Liquid Trap Bottle
65
Gas Ballasting the Roughing Pump
68
Gas Ballasting a Pump Fitted with a Screwdriver-Operated Gas Ballast Valve
69
Gas Ballasting a Pump Fitted with a Handle-Operated Gas Ballast Valve
70
Checking the Roughing Pump Oil Level
71
Adding Oil to the Roughing Pump
71
Cleaning the Source Components
73
Cleaning the Sample Cone and Gas Cone
74
Removing the Cone Gas Assembly from the Source
74
Disassembling the Cone Gas Assembly
77
Cleaning the Sample Cone and Gas Cone
78
Assembling the Cone Gas Assembly
81
Fitting the Cone Gas Assembly to the Source
82
Cleaning the Ion Block, Isolation Valve, and Extraction Cone
84
Removing the Ion Block Assembly from the Source Assembly
84
Disassembling the Source Ion Block Assembly
86
Cleaning the Ion Block, Isolation Valve, and Extraction Cone
94
Assembling the Source Ion Block Assembly
96
Fitting the Ion Block Assembly to the Source Assembly
99
Cleaning the Source Hexapole Assembly
101
Removing the Ion Block Assembly, Ion Block Support, and Hexapole from the Source Assembly
101
Cleaning the Hexapole Assembly
103
Fitting the Hexapole Assembly, PEEK Ion Block Support, and Ion Block Assembly to the Source Assembly
106
Replacing the ESI Probe Tip
108
Replacing the ESI Probe Sample Capillary
109
Replacing the Ion Block Source Heater
116
Replacing the Source Assembly Seals
121
Removing the Source Enclosure from the Instrument
121
Disassembling the Source Enclosure and Probe Adjuster Assembly
123
Fitting the New Source Enclosure and Probe Adjuster Assembly Seals
127
Assembling the Probe Adjuster Assembly and Source Enclosure
128
Fitting the Source Enclosure to the Instrument
129
Maintaining the Instrument Air Filters
131
Cleaning the Air Filter Inside the Instrument's Lower Bezel
131
Replacing the Air Filter Inside the Lower Bezel
132
Cleaning the Air Filter Behind the Source Probe
133
Replacing the Air Filter Behind the Source Probe
135
Replacing the Roughing Pump Oil
135
Replacing the Roughing Pump's Oil Demister Element
138
A Safety Advisories
145
Warning Symbols
146
Task-Specific Hazard Warnings
146
Specific Warnings
147
Caution Symbol
149
Warnings that Apply to All Waters Instruments
150
Electrical and Handling Symbols
154
Electrical Symbols
154
Handling Symbols
155
B External Connections
157
External Wiring and Vacuum Connections
158
Connecting the Oil-Filled Roughing Pump
159
Making the Electrical Connections for a Roughing Pump with an External Relay Box
164
Making the Electrical Connections for a Roughing Pump Without an External Relay Box
165
Connecting the Oil-Free Roughing Pump
166
Making the Electrical Connections for an Oil-Free Roughing Pump
173
Connecting to the Nitrogen Gas Supply
174
Connecting to the Collision Cell Gas Supply
176
Connecting the Nitrogen Exhaust Line
176
Connecting the Liquid Waste Line
179
Connecting the Workstation
181
Connecting Ethernet Cables
182
I/O Signal Connectors
182
Signal Connections
184
Connecting to the Electricity Source
187
C Materials of Construction and Compliant Solvents
189
Preventing Contamination
190
Items Exposed to Solvent
190
Solvents Used to Prepare Mobile Phases
191
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