Shimadzu LC-40D X3 CL Manuals

Manuals and User Guides for Shimadzu LC-40D X3 CL. We have 3 Shimadzu LC-40D X3 CL manuals available for free PDF download: System Manual, Instruction Manual, Safety Manualline

Shimadzu LC-40D X3 CL System Manual (338 pages)

Brand: Shimadzu | Category: Laboratory Equipment | Size: 22 MB

Introduction
4
Instruction Manual Components
4
Operating Nexera CL System
7
Table of Contents
8
Overview
15
System Features
15
LC-40D XR CL, LC-40D X3 CL, or LC-40B X3 CL Solvent Delivery Unit
15
SIL-40C XR CL or SIL-40C X3 CL Autosampler
16
CTO-40C CL Column Oven
17
CL UV-VIS Detector
17
Optional Parts
17
Configuration List
20
Switching on the Power Supply and Opening the [Realtime Analysis] Window
24
Switching on the Instruments Power Supply
24
Logging in to Labsolutions and Opening the [Realtime Analysis] Window
26
Specifying Analytical Conditions
29
Editing Methods
29
Placing Mobile Phases and Autosampler Rinse Solutions
36
Placing Mobile Phase and Rinse Solution Bottles on the Reservoir Tray
36
Performing Auto-Purging
38
Manual Purging the Solvent Delivery Pump
40
Attaching the Column
43
Attaching Columns in the Column Oven
43
Warming up the System
46
Placing Samples
48
Preparing Sample Vials (or Sample Plates)
48
Placing Samples in the Autosampler
50
Performing a Single Run Analysis
54
Check List to Confirm before Starting Analysis
54
Performing a Single Run Analysis
55
Performing Postrun Analysis
57
Displaying and Printing Data Reports
61
Performing Realtime Batch (Sequence) Analysis
62
Analyzing Multiple Sets of Data Using Data Browser
65
Outputting Summary Reports
67
Stopping Analysis and Shutting off the Power Supply
69
Check List to Confirm after Analysis Is Finished
69
Purging Columns with a Column Storage Solution
69
Shutting down the Instruments
70
Setting up Startup for Next Use
72
Key Points for Analysis
72
Before Analysis
72
Precautions for Selecting and Handling Mobile Phase Solvents
78
Precautions When Replacing the Mobile Phase
78
Precautions for Selecting an Autosampler Rinse Solution
79
Using Buffer Solutions as a Mobile Phase
82
Application Operations
84
Startup and Shutdown Functions
84
Startup Function
84
Executing the Startup Process
84
Executing a Startup Process and Starting a Batch Analysis at a Specified Date/Time
86
Shutdown Function
89
Executing the Shutdown Function
89
Executing a Batch File with a Shutdown Function Specified in the File
91
Auto-Diagnostics (Pulsation Check) and Auto-Recovery
95
Auto-Diagnostics (Pulsation Check)
95
Auto-Recovery
95
Autosampler Functions
99
Pretreatment Functions
99
Cut off Loop Function
102
Low Dispersion Injection
103
Batch Action Functions
103
Using ACTO (Analytical Condition Transfer and Optimization) Functions
107
Concentration Gradient Start Adjustment Function
107
Method Migration Functions
109
Useful Data Analysis Functions
112
I-Peakfinder
112
Column Management
114
Column Management Workflow
115
Setup for Labsolutions
116
Column Registration and Replacement (Discard)
120
Analysis with Labsolutions
129
Viewing the Acquisition Log
132
Hardware Validation
136
Hardware Validation Overview
136
Hardware Validation Classifications
136
Timing for Hardware Validation
136
Periodic Inspections
136
Routine Inspections
137
Inspections During Maintenance
137
Precautions for Periodic Inspections
137
Parts Required for Periodic Inspections
137
Periodic Inspection of Solvent Delivery Pumps
141
Inspection Item
141
Testing Flowrate Accuracy
141
Periodic Inspection of Autosamplers
144
Inspection Item
144
Injection Volume Accuracy Test
144
Temperature Accuracy Test
145
Periodic Inspection of Plate Changers
148
Inspection Item
148
Checking Temperature Accuracy
148
Periodic Inspection of Column Ovens
151
Inspection Item
151
Testing the Temperature Adjustment Function
151
Periodic Inspection of UV Absorbance Detectors
154
Inspection Item
154
Wavelength Accuracy Test
154
Periodic Inspections of Systems
160
Inspection Item
161
Absorbance Linearity Test
161
Noise/Drift Test
163
Gradient Concentration Test (Gradient System)
166
Reproducibility Test
170
Injection Linearity Test
173
Carryover Test
173
Corrective Measures if Control Criteria Are Not Satisfied
175
Troubleshooting
175
Troubleshooting
176
Errors and Operating Problems
176
Resolving Common Troubleshooting Issues
177
Communication Fails
177
Solvent Flow Does Not Stabilize
178
Solvent Delivery Pressure Increases
179
Baseline Does Not Stabilize
182
Noise Appears in Baseline
183
Poor Area Value Reproducibility
185
Carryover Does Not Disappear
188
Troubleshooting
189
Hardware Status
189
Symptoms Presumably Due to an Error, Based on a Chromatogram
198
List of Error Messages
208
System Controller
208
Pump
213
Autosampler
217
Column Oven
246
UV Detector
253
Selecting Components
259
Selecting a System
259
System Installation Arrangement
260
System Tubing
262
Ultra High-Speed Analysis
264
Selecting a Mixer
265
Selecting the Cell
266
Installation
267
Installing the System
267
Removing Items Used to Secure the System During Shipping
267
Installing the Autosampler
268
Installing the Solvent Delivery Pump
271
LC-40D X3 CL, or LC-40B X3 CL)
271
Installing the Detectors (SPD-40 CL)
272
Installing the Degassing Unit (DGU-405 CL)
273
Installing the Reservoir Tray
274
Installing the Column Oven (CTO-40C CL)
275
Installing Other Instruments
276
Cable Connections
277
Connecting the Power Cord
277
Connecting Optical Cables
277
Connecting a Degassing Unit (DGU-405 CL) to the Solvent Delivery Pump
281
Tubing Connections
284
Installing Tubes and Joints for Draining Leakage
286
Connecting Low-Pressure Flow Channel Tubing
295
Connecting Tubing for High-Pressure Flow Channels (Connection Methods)
308
Connecting Tubing for High-Pressure Flow Channels (Gradient Systems)
314
Connecting Tubing for High-Pressure Flow Channels (Isocratic Systems)
318
Checking Computer and System Controller Connections
319
Setting the Computer IP Address
320
Specifying Computer Browser Settings
322
Specifying System Controller Settings
324
Other Installation Processes
326
Connecting to Labsolutions
326
Connecting the Computer to the System Controller
326
Installing Optional Column Management Functionality
327
Addendum
330
Mobile Phase Properties
330
Index
337

Shimadzu LC-40D X3 CL Instruction Manual (144 pages)

Brand: Shimadzu | Category: Laboratory Equipment | Size: 7 MB

Introduction
4
Indications Used in this Manual
4
Operating Nexera CL System
5
Table of Contents
6
Overview
11
Features
11
Component Parts
12
Optional Parts
13
Parts Identification and Function
17
Front
17
Behind
18
Back
19
Right Side and Bottom
20
Name and Functions of the Operation Panel
21
Display Area
23
Operation Area
24
Settings for the Basic Operation
26
Prior to Key Operation
26
Setting Flow Rate
26
Setting Compressibility
26
Setting Maximum Pressure Limit
27
Setting Minimum Pressure Limit
28
Operation
29
Preparation before Operation
29
Operation in Constant Flow Delivery Mode
30
Operation in Constant Pressure Delivery Mode
31
Types of Screens
33
Monitoring Screens
34
Auxiliary Functions Screen (FUNCTION)
38
Auxiliary Functions (FUNCTION) List
38
PARAMETER] Setting Group
41
CONTROL] Setting Group
47
SYSTEM] Setting Group
48
UTILITY] Setting Group
54
FILE] Operation Group
56
VP Functions Screen
57
List of VP Functions
57
Product Information Group (PRODUCT INFO)
59
Maintenance Information Group (MAINTENANCE)
59
Validation Support Information Group (VALIDATION)
63
Calibration Support Information Group (CALIBRATION)
71
Creating Time Program
79
Time Program Command List
79
Time Program Setting Screen
80
Creating a Time Program
81
Creating a Low-Pressure Gradient Program
83
Deleting a Step
84
Starting and Stopping a Time Program
84
Commands Used for Time Programs Only
85
Delivery in the Low-Pressure Gradient Mode
86
Set Value
86
Preparation for Delivery
86
Connection with the System Controller or Workstation
88
Setting the Instrument
88
Basic Parameters
88
Connection to External Input/Output Terminals
88
Periodic Inspection and Maintenance
89
Prior to Inspection and Maintenance
89
List of Periodic Inspection and Maintenance
92
Check after Inspection and Maintenance
93
Removing the Right Panel Cover and the Filter Holder
94
Removing/Installing the Pump Heads
95
Replacing the Plunger Seal
102
Replacing the Plunger Seal and Backup Ring
102
Resetting the Delivery Amount
109
Check after Replacement
109
Cleaning/ Replacing the Plunger and Diaphragm
110
Removing the Pump Head and the Head Holder
111
Cleaning and Replacement of the Plunger and the Diaphragm
113
Rinsing the Check Valve
117
Performing an Ultrasonic Cleaning of the Check Valve
120
Replacing the Check Valve
122
Inspecting the Line Filter
124
Replacing the Line Filter
125
Cleaning/Replacing the Suction Filter
127
Replacing the Drain Valve
129
Replacing the Air Filter (Right Panel)
130
Cleaning of the Leak Tray
132
Cleaning the Exterior
132
Usual Cleaning
132
Decontamination Cleaning
133
Cleaning of the Automatic Rinsing Kit
133
Technical Information
135
Specifications
135
LC-40D X3 CL Specifications
135
LC-40D XR CL Specifications
136
High-Pressure Gradient System
137
Low-Pressure Gradient System
137
Other Specifications
138
Maintenance Parts
140
Consumable Parts
141
Replacement Parts
142
Maintenance Kit
143

Shimadzu LC-40D X3 CL Safety Manualline (42 pages)

Liquid Chromatograph

Brand: Shimadzu | Category: Laboratory Equipment | Size: 3 MB

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