Table of Contents
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Care and Use Procedures
Minimate
™
TFF Capsule
Table of Contents
Introduction . . . . . . . . . . . . . . . . . . . . . . . .2
Applications . . . . . . . . . . . . . . . . . . . . . . .2
Product Information . . . . . . . . . . . . . . . . .2
Instructions For Use . . . . . . . . . . . . . . . . .3
Installation . . . . . . . . . . . . . . . . . . . . . . . .3
Calibrate Feed Pump . . . . . . . . . . . . . . . .4
Flushing . . . . . . . . . . . . . . . . . . . . . . . . . .4
Sanitization . . . . . . . . . . . . . . . . . . . . . . .5
(Recommended for critical applications)
Normalized Water Permeability (NWP) . . . .5
(Optional)
System Hold-up Volume (Optional) . . . . . .5
Integrity Test (Optional) . . . . . . . . . . . . . . .5
Buffer-Conditioning (Optional) . . . . . . . . . .5
Concentration/Diafiltration . . . . . . . . . . . . .6
Product Recovery . . . . . . . . . . . . . . . . . . .6
Cleaning . . . . . . . . . . . . . . . . . . . . . . . . . .6
Storage of the Minimate TFF Capsules . . . .6
Disposal of the Minimate TFF Capsule . . . .6
Appendix A
Normalized Water Permeability . . . . . . . . .7
System Hold-up Volume . . . . . . . . . . . . .10
Minimate TFF Capsule Integrity Test . . . . .10
Flushing and Cleaning After Use . . . . . . .12
Specifications . . . . . . . . . . . . . . . . . . . . .14
Certification . . . . . . . . . . . . . . . . . . . . . .15
Ordering Information . . . . . . . . . . . . . . . .15
Support Literatures . . . . . . . . . . . . . . . . .15
Where to Find More Information . . . . . . .15
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Table of Contents
Related Manuals for Pall Minimate OA050C12
Summarization of Contents
Care and Use Procedures
Introduction
Overview of the Minimate TFF capsule and its use in biomolecule concentration and diafiltration.
Product Information
Details about the Minimate TFF Capsule and its included fittings package.
Instructions For Use
Step-by-step guide for setting up and operating the Minimate TFF Capsule system.
Installation
Procedures for connecting tubing and fittings to the Minimate TFF Capsule.
Calibrate Feed Pump
Method for calibrating the pump to ensure accurate flow rate settings.
Flushing
Steps to flush out preservatives and ensure membrane readiness for use.
Sanitization
Recommended procedures for sanitizing the capsule for critical applications.
Normalized Water Permeability (NWP) (Optional)
Procedure to measure membrane performance and evaluate cleaning effectiveness.
System Hold-up Volume (Optional)
Determining the total volume within the flow path for process calculations.
Integrity Test (Optional)
Methods to check for defects in the membrane or seals before or after use.
Buffer-Conditioning (Optional)
Preconditioning the capsule to the sample buffer before adding the sample.
Concentration/Diafiltration
Application notes for concentration and diafiltration processes using the capsule.
Product Recovery
Procedures to recover concentrated product from the system after processing.
Cleaning
Guidelines for cleaning the TFF capsule for reuse.
Storage of Minimate TFF Capsules
Recommended agents and conditions for storing the TFF capsules.
Disposal of Minimate TFF Capsule
Procedures for safely sterilizing and disposing of the TFF capsule.
Appendix A
Normalized Water Permeability
Detailed procedure for determining Normalized Water Permeability (NWP).
Appendix B
Specifications
Technical specifications of the Minimate TFF Capsule, including materials and dimensions.
Certification
Pall Corporation's certification statements for the Minimate TFF Capsule.
Where to Find More Information
Information on accessing additional documentation and support resources.
Ordering Information
Minimate TFF capsules
Product numbers and descriptions for Minimate TFF capsules with different Omega pore sizes.
Complementary Products
List of related accessories and their product numbers for the TFF system.
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Questions and answers