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Summary of Contents for Myr M-240
- Page 1 SEMI-AUTOMATED ROTARY MICROTOME MODEL M-240 User’s Manual Version 06/20 Keep this manual always with the instrument Read carefully before installing and working with the instrument...
- Page 2 We are committed to offer you the best and most reliable service. Don’t hesitate to contact your local dealer for any question related to this semi-automated rotary Microtome. Your Especialidades Médicas Myr, S.L. team. MYR M-240...
- Page 3 These are determined only by the contract provisions agreed between ourselves and our customers. MYR reserves the right to modify manufacturing processes as well as technical specifications without prior notice. That way is it possible to continuously improve the technology and manufacturing techniques used in our products.
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Page 4: Table Of Contents
Touch control MAIN Screen ................22 5.1.2.1 Coarse feed functions ..................22 5.1.2.2 SECTIONING and TRIMMING selections ............25 5.1.2.3 Touchscreen safety lock ..................25 5.1.3 Touch control MENU Screen ................26 5.1.3.1 Overview of structure of MENU screen............26 MYR M-240... - Page 5 5.1.3.2 Detailed description of MENU screen: INFO ........... 27 5.1.3.3 Detailed description of MENU screen: RETRACTION ........27 5.1.3.4 Detailed description of MENU screen: MEMORY DISTANCE ..... 28 5.1.3.5 Detailed description of MENU screen: ROCKING .......... 28 5.1.4 Touch control SETTINGS screen ..............29 5.1.4.1 Overview of structure of SETTINGS screen ............
- Page 6 Application hints ....................55 Instrument malfunctions detection ..............56 8.2.1 Malfunctions, possible causes and troubleshooting .......... 56 8.2.2 Error messages ....................57 Warranty and Service ..................58 Warranty confirmation ..................58 Service information ................... 58 End of service life....................58 MYR M-240...
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Page 7: Important Information
Important Information 1.1 Symbols in text and their understanding Warnings appear in a gray box and are marked by a warning symbol. Notes, i.e. important user information appears in a gray box and is marked by an information symbol. Numbers in parentheses refer to item numbers in illustrations Function keys which must be touched on the touch display are shown in the text in BOLD CAPITAL LETTERS Manufacturer... -
Page 8: Qualification Of Operating Personal
The instrument complies with applicable international safety regulations. 1.2 Qualification of operating personal The MYR M-240 Rotary Microtome must only be operated by educated and trained laboratory personnel. A designated user of this instrument must read these Instructions for Use carefully and must be familiar with all aspects of operation and safety precautions before starting out to operate the instrument. -
Page 9: Instrument Type And Identification
1.4 Instrument type and identification The MYR M-240 is a rotary microtome of the semi-motorized class offering a motorized feed and coarse feed operation. Specific care is applied for a smooth running and perfect balanced handwheel. Two sectioning modes are incorporated: conventional full handwheel rotation sectioning and rocking mode with alternating handwheel movements. -
Page 10: Safety Elements
The protective mechanisms and devices incorporated in the instrument must not be modified or removed by the user. Only qualified service personnel, certified by MYR, may service and repair the instrument and access the internal components of it. MYR M-240... -
Page 11: Warnings
2.2 Warnings The incorporated safety devices of this instrument only constitute the basis for accident prevention. It is above all the responsibility of the owner and on his part designated personnel, who operate, clean and service the instrument, to ensure a safe operation. Make sure to comply with the following instructions and warnings in order to ensure a safe and trouble-free operation. - Page 12 • When sectioning brittle specimen be aware of possible splinters and apply respective safety precautions • Do not place liquids on top of the instrument and make sure that no liquids can enter the interior of the instrument MYR M-240...
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Page 13: Integrated Safety Mechanisms
Hazards – servicing and cleaning • Only qualified and authorized service personnel may service and repair the instrument and access the interior of it • Before replacing fuses always switch off the instrument at the mains switch of the instrument and remove the power cord from the instrument. Then replace fuses of the correct specification according to 7.2.3 of this Instructions for Use •... -
Page 14: Finger-Guard On The Disposable Blade Carrier Dbc, Model Mr
Fig. 4 shows the disposable blade carrier DBC (1) with the finger-guard (2) in the non-protecting position. The cutting edge (5) is unprotected. This position should only be applied while actual sectioning is ongoing. Figure 4 MYR M-240... -
Page 15: Instrument Details And Specification
Instrument Details and Specification 3.1 Overview of instrument details and elements Figure 5 Figure 6 Instructions for Use - Version 06/20... -
Page 16: Technical Data
Depth (including waste tray) 540 mm Height 298 mm Working Height (cutting edge of blade/knife) 100 mm (measured from baseplate) Working Height (cutting edge of blade/knife) 173 mm (measured from table top) Weight 33,9 kg (included waste tray) MYR M-240... -
Page 17: Instrument Specifications
3.3 Instrument specifications Sectioning and trimming thickness settings 0,5 µm – 100 µm Section thickness setting range 0,5 µm – 5 µm Available setting selections from 0,5 µm increments – 20 µm from 5 µm 1 µm increments – 60 µm from 20 µm 5 µm increments... -
Page 18: Accessory Specifications
+/- 10 mm lateral shifting possible Finger-guard close/open by shifting sideways Quick release clamp QRC Cassette clamping all standard cassettes 38-42 x 28-29 mm Standard specimen clamp SSC Rectangular specimen blocks all rectangular specimens up to 55 x 50 mm MYR M-240... -
Page 19: Instrument Setup
Instrument Setup 4.1 Standard delivery content The MYR M-240 includes the following items as standard delivery content: Knife carrier model MR (base + segment + blade holder) Orienting head Quick release clamp Antistatic section waste tray Mains cord Allen key with handle Nr. 6... -
Page 20: Requirements On Installation Site
A red color in the middle window will indicate an unacceptable high mechanical shock in transport. Note that abnormality on the shipping documents and check the instrument and the accessories for possible damage! MYR M-240... - Page 21 Figure 7 For unpacking, remove the accessories packaging (1) and top foam (2). Then pull out the instrument (3) by grabbing under the front and the rear, thru the front and rear recesses (4) at the bottom foam support (5). Finally, remove the head immobilizer (6) once the lever is mounted on the handwheel. Keep the transport case and related packaging material together and store for eventually later shipping need such as return shipment or factory maintenance request.
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Page 22: Mounting Steps For Completion
(1). Washer (2) must sit between the handle (3) and the handwheel body. The handle should be smoothly rotatable. Finally attach Cover disk (6) to close the opening by pressing it in. Figure 10 MYR M-240... -
Page 23: Electrical Connections
4.5 Electrical connections The instrument must be connected to a grounded power socket. Only use a correct power cord which is certified for the country of installation of the instrument. Do not use extension cables! Checking power conditions! Before connecting the instrument to the line voltage at the site of installation, check that the actual power conditions fulfill the power requirements of the instrument. -
Page 24: Turning-On The Instrument
After about 3 s, the initialization is finished and the display shows the main screen. The instrument will now carry out automatically a feed system positioning routine. The horizontal drive mechanism will move the specimen head to the most rear position of the feed range. MYR M-240... -
Page 25: Instrument Operation
Instrument Operation 5.1 Operating elements and their functions 5.1.1 Instrument display - MAIN Screen Figure 12 The display is organized in fields which are indication fields only and fields which are touch buttons. The touch buttons are explained within chapters 5.1.2 onwards. The indication fields include a field to monitor the RETRACTION status of the instrument. - Page 26 The SC and SS indications can be reset at any time by the small RESET button (Fig.16) next to the right of the indication field. Figure 16 MYR M-240...
- Page 27 If none of the three possible indications would be selected by the user (see 5.1.3) the field may also be blank. In a situation where the Remaining Travel is below 1000µ (1mm), there will be a flashing indication of the frame of the Information field with flashing indication of the Remaining Travel value (Fig.
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Page 28: Touch Control Main Screen
Fig.22. A stepwise forward movement of the specimen takes place each time Figure 22 the button is pressed. The size of the step depends on the pre-selections of the SECT or TRIM values which are active at that moment. MYR M-240... - Page 29 The STOP button can be used in any situation while manipulating the horizontal coarse feed functions in forward or backward direction and will stop the movement. Figure 23 When the coarse feed movement is in continuous mode, for example COARSE FEED FAST BACKWARD, it will be indicated by a red color of the sign STOP.
- Page 30 Trimming and sectioning the new block can now start right from that position. Figure 31 If the sample block is moved away from the blade with the FAST-BACKWARDS key beyond the position stored in memory, the MEM key is disabled. MYR M-240...
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Page 31: Sectioning And Trimming Selections
5.1.2.2 SECTIONING and TRIMMING selections To select a sectioning or trimming value the SECT or TRIM button must be active. This is achieved by pressing the respective button which then will be highlighted in a white filed and with red writing. The selected value is always shown in the middle of the column of values and is also highlighted in a... -
Page 32: Touch Control Menu Screen
This button (Fig. 36) on the left lower side of the MENU screen leads back to the MAIN screen. (Moreover, this button is used also at other screens and always leads back to the previous screen) Figure 36 MYR M-240... -
Page 33: Detailed Description Of Menu Screen: Info
5.1.3.2 Detailed description of MENU screen: INFO With the choice of an INFO-source it will be determined which information is displayed on the information field on the MAIN screen (Fig. 12). There is a choice between RT=Remaining Travel, which is the remaining Figure 37 distance from the current position on the feed path up to the front-end limit. -
Page 34: Detailed Description Of Menu Screen: Memory Distance
When ROCKING is activated, the handwheel (1) operation may be also a reversing forward (clockwise) and backward (counterclockwise) movement and at each reversing into the clockwise direction, a triggering for sectioning or trimming feeds will take place. Figure 42 MYR M-240... -
Page 35: Touch Control Settings Screen
5.1.4 Touch control SETTINGS screen 5.1.4.1 Overview of structure of SETTINGS screen LANGUAGE: Selection out of 4 offered languages for user dialogue DISPLAY: two functions to select; the brightness of the screen can be adjusted from 2-100% and a screensaver function can be activated if a selected time out with no activity is reached CLOCK: Time and date are available within the system and can be set to local requirements... -
Page 36: Detailed Description Of Settings Screen: Display
The SYSTEM TIME can be set to any required time. Preferably it should be set to the local time at the institution of the instrument. Just enter the 6-digit ✓ format of the actual time and press for confirmation. Figure 49 MYR M-240... -
Page 37: Detailed Description Of Settings Screen: Sound
The SYSTEM DATE can be set to any required date. Preferably it should be set to the actual date. Just enter ✓ the 8-digit format of the actual date and press confirmation. Figure 50 5.1.4.5 Detailed description of SETTINGS screen: SOUND sound effect can be selected as acoustic feedback when touching a key or button. -
Page 38: Parameter Screen
5-250µ in increments of 1µm. select value CUSTOMER RETRACTION first press the X key to delete the existing value. Then type in a new value in the range of ✓ 5-250 and confirm by pressing the key. Figure 53 MYR M-240... -
Page 39: Knife Carrier Set-Up
Ensure that the selected retraction value is compatible with sectioning speed. If high retraction values are used, there could be not enough time to complete the retraction movement. 5.2 Knife Carrier set-up 5.2.1 Installing the Knife Carrier base The Knife Carrier consists of a Knife Carrier base part and, depending on the type of the used sectioning tool, a choice of upper parts. -
Page 40: Setting Up The Disposable Blade Holder Dbc, Model Mr
Figure 57 In order to ensure a perfect stability of the knife carrier, make sure that the levers are pushed in the correct locking position as indicated by the red dotted lines in Fig. 58. Figure 58 MYR M-240... -
Page 41: Setting Up The Disposable Blade Holder Dbc, Model Me
5.2.3 Setting up the Disposable Blade Holder DBC, model ME The Disposable Blade Carrier, model ME, serves as support and clamping device to use commercially available disposable microtome blades. It supports standardized low-profile blades as well as high profile blades. The Disposable Blade Carrier (DBC), model ME consists of a holder part sitting on the Knife Carrier base. -
Page 42: Adjusting The Clearance Angle
(4). After opening the clamping, the segment (2) can be swiveled on the base (3) and the required clearance angle (1) can be adjusted according to the angular scale which is engraved on the segment (2). Figure 63 MYR M-240... -
Page 43: Quick Release Clamp Set-Up
5.3 Quick release clamp set-up The Quick Release Clamp (QRC) (1) will be inserted to the Specimen Head (2) of the microtome by guiding the QRC (1) into the center opening of the Specimen Head (2). Thereby it must be observed that the side opening (3) of the Specimen Head (2) is matching in direction with the opening (4) at the shaft end of the QRC (1). -
Page 44: Clamping The Specimen
(see also 2.3.2!)! For a correct insertion of the disposable blade, pull the clamping lever down at a maximum angle of 40°, until the clamping plate is opened. Figure 69 MYR M-240... -
Page 45: Trimming Of Specimen
5.6 Trimming of specimen The sectioning process of a new specimen starts with the trimming of the, in general, uneven sectioning surface. Make sure that all clamping at the knife carrier and the specimen orientation as well as at the specimen holder are fastened and tight. Turn the handwheel of the microtome in clockwise direction and position the center part of the specimen surface opposite the sectioning tool e.g. -
Page 46: Daily Routine Essentials
Debris should be brushed away from all clamping devices around the specimen head, specimen clamp and knife carrier. After finished with the daily workload, cleaning of the devices and the instrument according 7.1 Cleaning the instrument should be followed. MYR M-240... -
Page 47: Optional Accessories
Optional Accessories 6.1 Overview of adaption for clamps 6.1.1 Rigid fixture for specimen clamps A Fixed Specimen Head (FSH) is available for an instrument set-up where no specimen orientation in x/y direction is required or wanted. A rotation of the specimen (z-direction) is possible all 360°. -
Page 48: Specimen Clamps And Holders
A simple pull at the lever grip (2) of the cassette opens the clamping jaw (3) of the cassette for inserting a cassette. A release of the grip will clamp the cassette by internal spring force. Figure 73 MYR M-240... -
Page 49: Knife Holder Base And Knife Holders
6.3 Knife holder base and knife holders 6.3.1 Knife carrier base The knife carrier base (1) is the universal base part for all types of knife carrier top parts. It is sitting on the microtome dovetail block (2) where it can be adjusted in longitudinal position and fixed via the clamping lever (3) located on the left side of the knife carrier base. -
Page 50: Knife Carrier For Disposal Blades Dbc, Model Me
The holder also incorporates a finger guard (4) Figure 77 for user protection. 6.4 Section waste tray A spacious Section Waste Tray with an easy to clean surface due to an antistatic coating is part of the standard delivery of the microtome. Figure 78 MYR M-240... -
Page 51: Cleaning And Maintenance
Cleaning and Maintenance 7.1 Cleaning the instrument Remove the microtome blade or knife always before detaching the knife carrier from the microtome! Put the knives always back into the knife box when not in use! Never place a knife anywhere with the cutting edge facing upwards! Never try to catch a falling knife! Do not use xylene or acetone as cleaning agents! When using cleaning agents, observe the safety instructions given by the... -
Page 52: Cleaning A Solid Knife
▪ Rotate the clamping lever (1) for the lateral clamping counterclockwise to open the clamping. Figure 79 ▪ Remove the DBC top part (2) from the middle part by shifting sideways. Figure 80 MYR M-240... - Page 53 ▪ Pull out completely the clamping lever (1) ▪ Unclamp the clearance angle fixation (3) by turning the clamping lever ccw. Figure 81 ▪ Detach the middle part (4) from the base part (5) by swiveling forward and disengage. Figure 82 ▪...
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Page 54: Cleaning The Disposable Blade Carrier, Model Me
Disassemble the DBC, model ME, for a comprehensive cleaning procedure by following these steps: ▪ Unclamp the clearance angle fixation by turning the clamping lever (3) ccw. ▪ Detach the holder part (1) from the base part (2) by swiveling forward and disengage. Figure 86 MYR M-240... - Page 55 ▪ Turn the clamping lever (3) ccw to unclamp the clamping plate (2). Move the clamping plate (2) sideways and take it off from the holder part (1). Figure 87 Do not use xylene or ethanol-based solvents to clean the knife carrier! ▪...
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Page 56: Cleaning The Quick Release Clamp Qrc
Do not use xylene or ethanol-based solvents to clean the Quick Release Clamp! Now clean the QRC. The best method is to place the assembly on an absorbent underlay in a drying chamber at a temperature of 65°C max. The paraffin will melt and will be soaked by the underlay. MYR M-240... -
Page 57: Maintenance
7.2 Maintenance 7.2.1 Maintenance instructions The instrument MYR M-240 is a robust instrument which is virtually maintenance free over a long period of time and usage. In order to ensure a long trouble-free operation and a long instrument life time it is recommended to conduct maintenance service on a regular basis. -
Page 58: Lubricating The Microtome And The Accessories
The following parts may need a slight lubrication (1-2 drops) depending on the frequency of their use. Lubrication may be applied as needed or on a regular basis every month. Please use Special Oil only: Instrument: ▪ Dovetail Block (2) ▪ Microtome base plate (1) Figure 94 ▪ Pulling Piece (4) Figure 95 MYR M-240... - Page 59 Accessories: Quick Release Clamp QRC ▪ Lever axle (right and left) (2) ▪ Clamping jaw recess (right and left) (1) Figure 96 Disposable Blade Carrier DBC, model MR ▪ Segment Link Piece (1) ▪ Clamping Lever lateral displacement (2) Figure 97 ▪...
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Page 60: Replacing Fuses
Open the door of the fuse compartment (1) Figure 100 Pull out the fuse holder (2) and replace defective fuses with correct rating and characteristic Push in the fuse holder (2) and close the door (1) Figure 101 MYR M-240... -
Page 61: Troubleshooting
It is divided into application-based problems and possible instrument malfunctions. For each problem possible causes and related corrective actions are listed. If a potential problem cannot be solved by applying the listed corrective action, inform your local MYR service provider. 8.1 Application hints Problem... -
Page 62: Instrument Malfunctions Detection
Power cable lose or not Check connection and plug no display presentation connected correctly The instrument is switched on but there is no initialization Mains fuse blown Replace mains fuse(s) (see movement and no display Chapter 7.1.1) activity MYR M-240... -
Page 63: Error Messages
8.2.2 Error messages In the event that a malfunction of the instrument is detected during the initialization process, an error message may occur in the information field of the display on the main screen: Error 1 indicates that the end of horizontal travel sensing of the feed mechanism did not work properly. -
Page 64: Warranty And Service
Instructions for Use. The scope of the warranty is limited to the content of the concluded purchase agreement. The terms of warranty of your MYR sales office or the local organization from which you have purchased this product shall apply exclusively. - Page 65 Especialidades Médicas Myr, S.L. c/ Lleida, 17-23 43712 Llorenç del Penedès – Spain Tel. +34.977.66.80.20 www.myr.com.es Instructions for Use - Version 06/20...
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