ZINEXTS MagPurix 24 EVO User Manual

ZINEXTS MagPurix 24 EVO User Manual

Automated nucleic acid purification system
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Automated Nucleic Acid Purification System
Catalog No.: ZP01019
Manual No.: QW-IH01-20
Version: 3.0
Zinexts Life Science Corp.
User Manual
Obelis s.a.
Bd Général Wahis 53
1030 Brussels Belgium
Tel: +(32) 2 732-59-54
Fax: +(32) 2 732-60-03
mail@obelis.net
24 EVO

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Summary of Contents for ZINEXTS MagPurix 24 EVO

  • Page 1 Zinexts Life Science Corp. User Manual Automated Nucleic Acid Purification System 24 EVO Catalog No.: ZP01019 Manual No.: QW-IH01-20 Version: 3.0 Obelis s.a. Bd Général Wahis 53 1030 Brussels Belgium Tel: +(32) 2 732-59-54 Fax: +(32) 2 732-60-03 mail@obelis.net...
  • Page 2: Table Of Contents

    2.2 External Features ......................... 8 2.3 Internal Features ......................... 9 3 Installation ........................... 10 3.1 Components of the MagPurix 24 EVO System ............10 3.2 Operating Environment / Conditions ................ 11 3.3 Installation Procedures ....................12 3.3.1 Unpacking ........................12 3.3.2 Control Unit ........................
  • Page 3 6.2 Cleaning of Piston ......................27 7 Troubleshooting ........................ 28 8 Specifications ........................33 8.1 UPS Specification ......................33 8.2 EMC ............................33 8.3 Safety ............................ 33 9 Contact ..........................34 9.1 Manufacturer Information ..................... 34 www.zinexts.com MagPurix 24 EVO User Manual 2 / 35...
  • Page 4 9.2 Technical Support ......................34 10 Warranty Information ...................... 34 Revision History ........................35 www.zinexts.com MagPurix 24 EVO User Manual 3 / 35...
  • Page 5: Introduction

    The MagPurix 24 EVO System is designed for the automated extraction and isolation of nucleic acids, utilizing advanced magnetic bead separation technology.
  • Page 6: Safety Symbols & Labels

    WARNING : Ignoring the following notations may lead to fire or electric shock, and to device failure.  Make sure the MagPurix 24 EVO System is installed in a well-ventilated environment and away from any water source.  Use a power cable that meets your country’s standard, or contact your local distributor/agent.
  • Page 7: About Reagent Kits

     Make sure the power source used is matching the rating as labeled on the MagPurix 24 EVO System.  Do not use the MagPurix 24 EVO System with a damaged power plug or a loose socket.  When you disconnect the plug from the outlet, be sure to hold the power plug itself, and don’t pull the power cable.
  • Page 8: About Samples

     When you use a third-party company to dispose of wastes, outsource this work to an operator licensed to handle medical waste subject to special control, and give them the medical waste manifest at the same time. www.zinexts.com MagPurix 24 EVO User Manual 7 / 35...
  • Page 9: Intended Use & General Description

    2 Intended Use & General Description 2.1 Intended Use The MagPurix 24 EVO System and any of its accessories is intended to be used to extract DNA and/or RNA from various sample types. The MagPurix 24 EVO System is intended to be used only in combination with extraction kits indicated for use with MagPurix System, for the applications described in the respective kit handbooks.
  • Page 10: Internal Features

    2.3 Internal Features www.zinexts.com MagPurix 24 EVO User Manual 9 / 35...
  • Page 11: Installation

    Please make sure all components are free of damages as soon as you get the system. If any damage is found, please contact your local distributor/agent for support. Note: The Zinexts Life Science Corp. global warranty does not cover transportation damages or improper handling and operation.
  • Page 12: Operating Environment / Conditions

    Use the MagPurix 24 EVO System in a location that meets the following conditions:  The MagPurix 24 EVO System must be placed at a minimum distance of 5 – 10 cm from all sidewalls and other instruments, to allow appropriate air circulation.
  • Page 13: Installation Procedures

    ◼ Connect the barcode reader to the instrument. ◼ Turn on the power of the MagPurix 24 EVO System with the switch on the right side of the ◼ instrument. The system will start the initialization and it will release the fixing material (white foam) ◼...
  • Page 14: Consumables For Extraction

    ◼ Important: Please keep and store the shipping box and the fixing material (white foam, transport locks), as it will be needed for any transport of the MagPurix 24 EVO System again. 3.3.3 Consumables for Extraction Note: Extraction reagent kits and consumables are not provided with the instrument and need to be ordered separately.
  • Page 15: Welcome & Login Screen

    4.1 Welcome & Login Screen After powering up the MagPurix 24 EVO System, the MagPurix 24 EVO System will start the ◼ initialization process. Click “LOGIN” and User ID and Password will appear for input. Set up the local time.
  • Page 16 Step 1- Remove the Camera as below  Step 2- Turn on the instrument and click on “Settings” → “System”  Step 3- Click “CAMERA” to turn off sensor  www.zinexts.com MagPurix 24 EVO User Manual 15 / 35...
  • Page 17 Step 5- Camera will start recording automatically after sensor is turned off. Press “OK”  button to pause. Step 6- Long press “M” button to access to Menu  Step 7- Press “M” button again to next page  www.zinexts.com MagPurix 24 EVO User Manual 16 / 35...
  • Page 18 ▲▼  Step 10- Press “M” button to return to the main menu  Step 11- On the panel, click “CAMERA” to turn on sensor. Then place Camera back on  www.zinexts.com MagPurix 24 EVO User Manual 17 / 35...
  • Page 19: Main Screen

    Once logged in, you will be able to set up at least 10 other users with their own passwords. ◼ 4.2 Main Screen The Main Screen of the MagPurix 24 EVO provides access to all functions of the system on the right MagPurix 24 EVO System.
  • Page 20: Instrument Startup And Operation

    Biohazard: Always wear appropriate gloves, a mask, and safety goggles before, during and after the operation of the instrument, as some reagents used with the MagPurix 24 EVO System may be hazardous or may become hazardous after completion of the processed protocols and/or some samples used with this instrument may contain infectious agents.
  • Page 21: Start Up The System

    5.2 Start up the System Please make sure that the plug of the MagPurix 24 EVO System is securely connected to a grounded power socket and that the power source used is matching the rating as labeled on the MagPurix 24 EVO System.
  • Page 22: Perform Extraction

    5.3 Perform Extraction Note: Before operating the MagPurix 24 EVO System, please prepare all items necessary to run the instrument, as described in Chapter 5.1. After logging in to the MagPurix 24 EVO Software, the Main Screen opens. Click the “Perform ◼...
  • Page 23 The position of Piercing Pin (on the right) and Filter Tip (on the left) are as follows. The middle row of the Tip Holder should be empty. Start Extraction process: ◼ www.zinexts.com MagPurix 24 EVO User Manual 22 / 35...
  • Page 24 Note: Zinexts does not guarantee with expired kit performance. www.zinexts.com MagPurix 24 EVO User Manual 23 / 35...
  • Page 25: System Fixing Before Transportation

    5.4 System Fixing before Transportation Enter the “Settings” menu and select “Fixing” and press “Yes”. Then place the Fixing Material (White Foam) at the position of cartridge holder. www.zinexts.com MagPurix 24 EVO User Manual 24 / 35...
  • Page 26: Cleaning & Maintenance

    MagPurix 24 EVO System. Important: If liquid is spilled on the MagPurix 24 EVO System worktables, wipe it away as soon as the run has finished, using a soft cloth and de-ionized water, followed by 75% Ethanol. Do not allow the liquid to dry.
  • Page 27: Cleaning Of Rubbish Tray And M Motor

    Schedule Maintenance Type Performed by Preventive (for details of the procedures please refer to the MagPurix 24 EVO Service Manual) Grease ball screws if required  6-months to Check motor function & axis calibration 12-months Service Engineer  interval Check air-tight status of the piston units ...
  • Page 28: Cleaning Of Piston

    ◼ Enter “Settings” menu to select “System”, and then click “Piston”. ◼ Clean piston with 75% ethanol using soft cloth. Change new piston if there is significant impurity stain or salt crystal. www.zinexts.com MagPurix 24 EVO User Manual 27 / 35...
  • Page 29: Troubleshooting

    Note: You cannot resume the protocol after stopping it, you may lose your samples. 2. Turn off the power and remove all samples and consumables. Contact your local representatives. www.zinexts.com MagPurix 24 EVO User Manual 28 / 35...
  • Page 30 Leakage from Filter Tips or Air leakage on the Filter Tip. Replace the air-leaking tip with uneven liquid handling new one. between Filter Tips. www.zinexts.com MagPurix 24 EVO User Manual 29 / 35...
  • Page 31 Poor quality of starting Be sure to process samples material. immediately after collection or store the samples at appropriate temperature. The yield and the quality of isolated DNA depend on the starting material. www.zinexts.com MagPurix 24 EVO User Manual 30 / 35...
  • Page 32 Eluate containing DNA Magnetic beads present in the Remove any magnetic beads is discolored. eluate. using a magnetic separator, or centrifuge the sample in a microcentrifuge for 1 minute at maximum speed. www.zinexts.com MagPurix 24 EVO User Manual 31 / 35...
  • Page 33 Avoid repeated freezing thawing. DNA contaminated with Maintain a sterile environment DNase. while working (i.e., wear gloves and use DNase-free reagents). For any other technical issues/errors please contact your local distributor/agent. www.zinexts.com MagPurix 24 EVO User Manual 32 / 35...
  • Page 34: Specifications

    F 5A 250 V 8.1 UPS Specification On-Line, 1.5kVA/1200W, Battery energy (Watt-hours): 500 Wh 8.2 EMC EN 61326- 1:2013 (IEC 61326-1:2012), EN 61326-2-6:2013 (IEC 61326-2-6:2012) 8.3 Safety IEC/EN61010- 1, IEC/EN 61010-2-101 www.zinexts.com MagPurix 24 EVO User Manual 33 / 35...
  • Page 35: Contact

    Center. 10 Warranty Information Zinexts Life Science Corp. warrants that each product described herein will be free from defects in materials and workmanship for a period of twelve (12) months from the date of delivery. Zinexts Life Science Corp. agrees, as its sole responsibility under this limited warranty, and upon prompt notice of a defect, to repair or replace any product discovered to be defective within the warranty period.
  • Page 36 Zinexts Life Science Corp.. in any way. In no event will Zinexts Life Science Corp. be liable for any special, incidental, or consequential damages resulting from use or malfunction of this product or the equipment or system with which it is used, loss of revenue, or cost of replacement goods.

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