cytiva pH/C-902 Instructions Manual
cytiva pH/C-902 Instructions Manual

cytiva pH/C-902 Instructions Manual

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pH/C-902
Instruction
Important user information
All users must read the entire instructions to fully understand the
safe use of pH/C-902.
Safety notices
WARNING
WARNING indicates a hazardous situation
which, if not avoided, could result in death or
serious injury. It is important not to proceed until
all stated conditions are met and clearly
understood.
CAUTION
CAUTION indicates a hazardous situation which,
if not avoided, could result in minor or moderate
injury. It is important not to proceed until all
stated conditions are met and clearly
understood.
Note: A note is used to indicate information that is important for
trouble-free and optimal use of the product.
Declaration of conformity
This product meets the requirements of applicable CE-directives
when installed and used in an ÄKTAprocess™ system. A copy of the
corresponding Declaration of Conformity for the ÄKTAprocess
system is available on request.
The CE marking and the corresponding EU Declaration of Conformity
is valid for the instrument when it is:
used according to the Operating Instructions or user manuals,
and
used in the same state as it was delivered, except for alterations
described in the Operating Instructions or user manuals.
Introduction
The pH/C-902 Monitor is a high precision on-line monitor for
measurement of pH and conductivity in high performance liquid
chromatography applications.
cytiva.com
The monitor is suitable for pH and conductivity measurements in
pharmaceutical applications where monitoring of running conditions
is critical.
The pH/C-902 Monitor is a combined monitor with two independent
measuring channels for both pH and conductivity.
The pH/C-902 features:
Two separate pH measuring channels
Two separate conductivity measuring channels
Fast response
High accuracy and reproducibility
Flow cells with small dead volume
Flow cells that can be connected close together, minimizing band
broadening and time delays between detectors.
Control via UNICORN™ software only.
Safety
The instrument is designed for indoor use only
Do not use the instrument in a dusty environment or close to
spraying water
Only use the instrument in accordance with local safety
regulations
WARNING
The instrument must not be opened by the user.
WARNING
Always disconnect the power supply before
attempting to replace any item on the
instrument during maintenance.
WARNING
The instrument power supply must be connected
to a grounded mains socket.
14003958 AB

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Summary of Contents for cytiva pH/C-902

  • Page 1 All users must read the entire instructions to fully understand the is critical. safe use of pH/C-902. The pH/C-902 Monitor is a combined monitor with two independent Safety notices measuring channels for both pH and conductivity. The pH/C-902 features: WARNING •...
  • Page 2: Installation

    However, it is also recommended that the flow cell is recalibrated after cleaning. The pH/C-902 Monitor has no user interface for the operator. It is controlled entirely via UNICORN control software (version 5.0 or The cell constant is adjusted in the UNICORN System Control later).
  • Page 3 Note: When running chromatography using organic solvents it is recommended that the pH electrode is removed and the Fig 1. Conductivity of 1.00 M NaCl at 20-30℃ dummy electrode is inserted in its place, as organic solvents will cause pH electrode degeneration. pH/C-902 Instruction 14003958 AB...
  • Page 4 Storage CAUTION Never leave the pH electrode in the flow cell for any period of time when the system is not used since this may cause the glass membrane of the electrode to dry out. pH/C-902 Instruction 14003958 AB...
  • Page 5: Maintenance

    60 – 80°C. CAUTION Place the electrode tip in the heated KNO solution. Only spare parts approved or supplied by Cytiva Allow the electrode to cool while immersed in the KNO may be used for maintaining and servicing the solution before retesting.
  • Page 6: Troubleshooting

    It is recommended that the pH Faults and actions electrode is not used in applications If the suggested actions do not correct the fault, call Cytiva. using organic solvents. Replace the electrode with the pH plug. pH measurement 12.
  • Page 7: Reference Information

    Error messages system. If error message reappears or conductivity cell is already connected, If the suggested actions do not correct the fault, call Cytiva. contact service engineer. pH monitor Error in temp sensor If conductivity cell (where temperature...
  • Page 8: Conductivity Cell

    For use in: 6mm Polypropylene systems 3/8” Stainless steel systems 10 mm For use in: 10mm Polypropylene systems 1/2” Stainless steel systems 22 mm For use in: 1” systems (PP and SS) Fig 5. Conductivity cell – principle pH/C-902 Instruction 14003958 AB...
  • Page 9 Back pressure Max 0.1 bar at 600 l/h (8 mm cell) cytiva.com/bioprocess Cytiva and the Drop logo are trademarks of Global Life Sciences IP Holdco LLC or an affiliate. ÄKTAprocess and UNICORN are trademarks of Global Life Sciences Solutions USA LLC or an affiliate doing business as Cytiva.

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